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The ADAMs family of metalloproteases: multidomain proteins with multiple functions

Data up to Jan 2025

Published2003
Citations1,052
References199

Total Citations Per Year

Abstract

References (199)

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

1997 • 3,094 citations

The Biology of Chemokines and their Receptors

2000 • 2,416 citations

Tissue inhibitors of metalloproteinases: evolution, structure and function

2000 • 1,873 citations

Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

2001 • 1,715 citations

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

1997 • 1,608 citations

An Essential Role for Ectodomain Shedding in Mammalian Development

1998 • 1,607 citations

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

1999 • 1,484 citations

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1996 • 1,473 citations

Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype

1995 • 1,457 citations

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

1990 • 1,423 citations

Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease

1999 • 1,115 citations

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

2002 • 1,108 citations

A Novel Proteolytic Cleavage Involved in Notch Signaling

2000 • 1,080 citations

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

1995 • 1,035 citations

Strain-Dependent Epithelial Defects in Mice Lacking the EGF Receptor

1995 • 1,016 citations

Notch Signaling: From the Outside In

2000 • 958 citations

The selecting: vascular adhesion molecules

1995 • 954 citations

Seven-transmembrane-spanning receptors and heart function

2002 • 926 citations

Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor

1998 • 922 citations

Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

2002 • 846 citations

A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1

2000 • 841 citations

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10

2001 • 788 citations

Development of Matrix Metalloproteinase Inhibitors in Cancer Therapy

2001 • 788 citations

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

1997 • 782 citations

Families of zinc metalloproteases

1994 • 769 citations

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

2002 • 727 citations

The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases

1995 • 691 citations

A potential fusion peptide and an integrin ligand domain in a protein active in sperm–egg fusion

1992 • 680 citations

The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis

2001 • 677 citations

MEMBRANE-ANCHORED GROWTH FACTORS

1993 • 676 citations

TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice

1993 • 659 citations

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

2002 • 657 citations

Tumor Necrosis Factor-α-converting Enzyme (ADAM17) Mediates the Cleavage and Shedding of Fractalkine (CX3CL1)

2001 • 623 citations

Epidermal growth factor receptors: critical mediators of multiple receptor pathways

1999 • 610 citations

The ADAM gene family: surface proteins with adhesion and protease activity

2000 • 582 citations

Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding

1999 • 558 citations

Determination of protease cleavage site motifs using mixture-based oriented peptide libraries

2001 • 547 citations

A metalloprotease-disintegrin, MDC9/meltrin-gamma /ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor

1998 • 523 citations

Regulated Cleavage of a Contact-Mediated Axon Repellent

2000 • 522 citations

Kuzbanian Controls Proteolytic Processing of Notch and Mediates Lateral Inhibition during Drosophila and Vertebrate Neurogenesis

1997 • 516 citations

Fertilization Defects in Sperm from Mice Lacking Fertilin β

1998 • 497 citations

Functional Analysis of the Domain Structure of Tumor Necrosis Factor-α Converting Enzyme

2000 • 496 citations

TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5)

2001 • 493 citations

A metalloprotease-disintegrin participating in myoblast fusion

1995 • 492 citations

Mouse egg integrin α6β1functions as a sperm receptor

1995 • 472 citations

ADAMs: focus on the protease domain

1998 • 472 citations

Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor

1997 • 456 citations

Tumor Necrosis Factor-α Converting Enzyme (TACE) Regulates Epidermal Growth Factor Receptor Ligand Availability

2002 • 415 citations

Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian

1999 • 413 citations

Diverse Cell Surface Protein Ectodomains Are Shed by a System Sensitive to Metalloprotease Inhibitors

1996 • 404 citations

The in vitro activity of ADAM‐10 is inhibited by TIMP‐1 and TIMP‐3

2000 • 396 citations

Defining brain wiring patterns and mechanisms through gene trapping in mice

2001 • 391 citations

Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

2001 • 385 citations

Crystal structure of the catalytic domain of human tumor necrosis factor-α-converting enzyme

1998 • 376 citations

Molecular mechanisms regulating myogenic determination and differentiation

2000 • 375 citations

Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion.

1987 • 368 citations

Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells

2002 • 354 citations

Intracellular maturation and localization of the tumour necrosis factor α convertase (TACE)

2000 • 350 citations

Tumor necrosis factor-α converting enzyme

2002 • 341 citations

ADAMTS: a novel family of extracellular matrix proteases

2001 • 339 citations

KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis

1996 • 331 citations

Protein Kinase C-dependent α-Secretase Competes with β-Secretase for Cleavage of Amyloid-β Precursor Protein in the Trans-Golgi Network

2000 • 320 citations

The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein–coupled receptors

2002 • 318 citations

A Novel, Secreted Form of Human ADAM 12 (Meltrin α) Provokes Myogenesis in Vivo

1998 • 315 citations

Metalloprotease-Disintegrin MDC9: Intracellular Maturation and Catalytic Activity

1999 • 312 citations

Tumor Necrosis Factor-α-converting Enzyme Is Required for Cleavage of erbB4/HER4

2000 • 310 citations

ADAM 12-S Cleaves IGFBP-3 and IGFBP-5 and Is Inhibited by TIMP-3

2000 • 309 citations

Extracellular Signal-regulated Kinase Phosphorylates Tumor Necrosis Factor α-converting Enzyme at Threonine 735: A Potential Role in Regulated Shedding

2002 • 296 citations

Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme

1995 • 289 citations

Neutrophil rolling altered by inhibition of L-selectin shedding in vitro

1996 • 285 citations

The Disintegrins ADAM10 and TACE Contribute to the Constitutive and Phorbol Ester-regulated Normal Cleavage of the Cellular Prion Protein

2001 • 285 citations

Neuregulin, a factor with many functions in the life of a Schwann cell

2000 • 282 citations

Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein

1999 • 260 citations

Analysis of Loss of Adhesive Function in Sperm Lacking Cyritestin or Fertilin β

2001 • 258 citations

Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades

1999 • 248 citations

The Cysteine-Rich Domain of Human Adam 12 Supports Cell Adhesion through Syndecans and Triggers Signaling Events That Lead to β1 Integrin–Dependent Cell Spreading

2000 • 246 citations

Regulation of the α‐secretase ADAM10 by its prodomain and proprotein convertases

2001 • 232 citations

kuzbanian-mediated cleavage of Drosophila Notch

2002 • 226 citations

Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin α6β1: Implications for murine fertilization

1999 • 223 citations

Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence.

1990 • 219 citations

Specific Interaction of the Recombinant Disintegrin-like Domain of MDC-15 (Metargidin, ADAM-15) with Integrin αvβ3

1998 • 214 citations

Insulin-Like Growth Factor Binding Proteins: New Proteins, New Functions

1999 • 213 citations

MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.

1996 • 213 citations

RGD-independent Binding of Integrin α9β1 to the ADAM-12 and -15 Disintegrin Domains Mediates Cell-Cell Interaction

2000 • 211 citations

Cysteine-Rich Domain of Human ADAM 12 (Meltrin α) Supports Tumor Cell Adhesion

1999 • 209 citations

Mice Lacking the Metalloprotease-Disintegrin MDC9 (ADAM9) Have No Evident Major Abnormalities during Development or Adult Life

2002 • 209 citations

Calmodulin Regulates L-Selectin Adhesion Molecule Expression and Function through a Protease-Dependent Mechanism

1998 • 204 citations

Identification and Characterization of a Pro-tumor Necrosis Factor-α-processing Enzyme from the ADAM Family of Zinc Metalloproteases

1997 • 204 citations

Interaction of metargidin (ADAM-15) with αvβ3 and α5β1 integrins on different haemopoietic cells

1999 • 193 citations

Meltrin γ (ADAM-9) mediates cellular adhesion through α6β1 integrin, leading to a marked induction of fibroblast cell motility

2000 • 190 citations

Human ADAM 12 (Meltrin α) Is an Active Metalloprotease

1998 • 188 citations

Role of Src Kinases in the ADAM-mediated Release of L1 Adhesion Molecule from Human Tumor Cells

2000 • 186 citations

The Shedding of Membrane-anchored Heparin-binding Epidermal-like Growth Factor Is Regulated by the Raf/Mitogen-activated Protein Kinase Cascade and by Cell Adhesion and Spreading

1999 • 185 citations

The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila

1996 • 183 citations

Interaction of the Metalloprotease Disintegrins MDC9 and MDC15 with Two SH3 Domain-containing Proteins, Endophilin I and SH3PX1

1999 • 182 citations

ADAM 12, a Disintegrin Metalloprotease, Interacts with Insulin-like Growth Factor-binding Protein-3

2000 • 182 citations

Roles of Meltrin β/ADAM19 in the Processing of Neuregulin

2001 • 181 citations

Reactive oxygen species mediate tumor necrosis factor alpha‐converting, enzyme‐dependent ectodomain shedding induced by phorbol myristate acetate

2000 • 180 citations

Coordinated Expression of β‐Amyloid Precursor Protein and the Putative β‐Secretase BACE and α‐Secretase ADAM10 in Mouse and Human Brain

2000 • 179 citations

Normal Fertilization Occurs with Eggs Lacking the Integrin α6β1 and Is Cd9-Dependent

2000 • 178 citations

Heparin-binding EGF-like growth factor

1997 • 172 citations

Metargidin, a Membrane-anchored Metalloprotease-Disintegrin Protein with an RGD Integrin Binding Sequence

1996 • 170 citations

Shedding of interleukin-6 receptor and tumor necrosis factor α

2000 • 168 citations

Intracellular Maturation of the Mouse Metalloprotease Disintegrin MDC15

1998 • 167 citations

Function of an Axonal Chemoattractant Modulated by Metalloprotease Activity

2000 • 165 citations

Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration

2001 • 162 citations

Functional Classification of ADAMs Based on a Conserved Motif for Binding to Integrin α9β1

2002 • 159 citations

The Metalloprotease Disintegrin ADAM8

2002 • 159 citations

TACE and other ADAM proteases as targets for drug discovery

2001 • 156 citations

Specific Sequence Elements Are Required for the Expression of Functional Tumor Necrosis Factor-α-converting Enzyme (TACE)

1999 • 156 citations

SUP-17, a Caenorhabditis elegans ADAM protein related to Drosophila KUZBANIAN, and its role in LIN-12/NOTCH signalling

1997 • 155 citations

Binding of ADAM12, a Marker of Skeletal Muscle Regeneration, to the Muscle-specific Actin-binding Protein, α-Actinin-2, Is Required for Myoblast Fusion

2000 • 154 citations

Characterization of the Binding of Recombinant Mouse Sperm Fertilin β Subunit to Mouse Eggs: Evidence for Adhesive Activity via an Egg β1Integrin-Mediated Interaction

1997 • 153 citations

The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs

1997 • 152 citations

TNF-α-Converting Enzyme Cleaves the Macrophage Colony-Stimulating Factor Receptor in Macrophages Undergoing Activation

2001 • 150 citations

Fertilin β and other ADAMs as integrin ligands: insights into cell adhesion and fertilization

2001 • 145 citations

Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism.

1995 • 144 citations

The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs

2002 • 144 citations

Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-α converting enzyme

2001 • 143 citations

Refined 2·0 Å X-ray Crystal Structure of the Snake Venom Zinc-endopeptidase Adamalysin II

1994 • 142 citations

Distinctive effects of the viral oncogenes myc, erb, fps, and src on the differentiation program of quail myogenic cells.

1985 • 141 citations

Structure, function and evolutionary relationship of proteins containing a disintegrin domain

1992 • 138 citations

Shedding light on sheddases: role in growth and development

2002 • 134 citations

Biochemical and Pharmacological Criteria Define Two Shedding Activities for TRANCE/OPGL That Are Distinct from the Tumor Necrosis Factor α Convertase

2001 • 133 citations

Purification of ADAM 10 from bovine spleen as a TNFα convertase

1997 • 133 citations

Metalloprotease-dependent Protransforming Growth Factor-α Ectodomain Shedding in the Absence of Tumor Necrosis Factor-α-converting Enzyme

2001 • 133 citations

TNF-alpha convertase enzyme from human arthritis-affected cartilage: isolation of cDNA by differential display, expression of the active enzyme, and regulation of TNF-alpha.

1998 • 130 citations

Transendothelial migration of lymphocytes across high endothelial venules into lymph nodes is affected by metalloproteinases

2001 • 130 citations

Multiple signals activate cleavage of the membrane transforming growth factor-alpha precursor.

1991 • 129 citations

Phosphorylation-dependent Interactions between ADAM15 Cytoplasmic Domain and Src Family Protein-tyrosine Kinases

2002 • 128 citations

Tissue Inhibitor of Metalloproteinases-3 Inhibits Shedding of L-selectin from Leukocytes

1999 • 126 citations

Regulation of Human ADAM 12 Protease by the Prodomain

1999 • 125 citations

Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28

2000 • 123 citations

Sequence-Specific Interaction between the Disintegrin Domain of Mouse ADAM 3 and Murine Eggs: Role of β1 Integrin-associated Proteins CD9, CD81, and CD98

2001 • 122 citations

The Metallo-Disintegrin ADAM10 (MADM) from Bovine Kidney Has Type IV Collagenase Activityin Vitro

1998 • 121 citations

Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity

2002 • 121 citations

Role of the Juxtamembrane Domains of the Transforming Growth Factor-α Precursor and the β-Amyloid Precursor Protein in Regulated Ectodomain Shedding

1997 • 120 citations

Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin-binding EGF-like growth factor independently of protein kinase C

1998 • 119 citations

The Role of ADAM 15 in Glomerular Mesangial Cell Migration

2002 • 117 citations

Constitutive Proteolysis of the ErbB-4 Receptor Tyrosine Kinase by a Unique, Sequential Mechanism

1997 • 117 citations

Cell Volume-dependent Regulation of L-selectin Shedding in Neutrophils

1999 • 115 citations

ADAM 23/MDC3, a Human Disintegrin That Promotes Cell Adhesion via Interaction with the αvβ3 Integrin through an RGD-independent Mechanism

2000 • 115 citations

Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase

2014 • 112 citations

New Type of Metalloproteinase Inhibitor: Design and Synthesis of New Phosphonamide-Based Hydroxamic Acids

2002 • 110 citations

Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes: functional consequences for neutrophil aggregation.

1996 • 106 citations

Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase

2001 • 105 citations

CD156 (Human ADAM8): Expression, Primary Amino Acid Sequence, and Gene Location

1997 • 104 citations

Spatially- and temporally-restricted expression of meltrin α (ADAM12) and β (ADAM19) in mouse embryo

1998 • 102 citations

Expression of Members of the Novel Membrane Linked Metalloproteinase Family ADAM in Cells Derived from a Range of Haematological Malignancies

1997 • 102 citations

Cutting edge: a dominant negative form of TNF-alpha converting enzyme inhibits proTNF and TNFRII secretion.

1999 • 101 citations

Sequence-specific Interaction between the Disintegrin Domain of Mouse ADAM 2 (Fertilin β) and Murine Eggs

2000 • 100 citations

TNF-α Convertase Enzyme from Human Arthritis-Affected Cartilage: Isolation of cDNA by Differential Display, Expression of the Active Enzyme, and Regulation of TNF-α

1998 • 99 citations

Evidence that Distinct States of the Integrin α6β1 Interact with Laminin and an ADAM

1999 • 96 citations

A secreted form of human ADAM9 has an α-secretase activity for APP

2002 • 96 citations

L-selectin shedding does not regulate human neutrophil attachment, rolling, or transmigration across human vascular endothelium in vitro.

1997 • 92 citations

New α-Substituted Succinate-Based Hydroxamic Acids as TNFα Convertase Inhibitors

1999 • 90 citations

The role of cell adhesion molecule L1 in axonal extension, growth cone motility, and signal transduction

1997 • 89 citations

ADAM13 Disintegrin and Cysteine-rich Domains Bind to the Second Heparin-binding Domain of Fibronectin

2002 • 89 citations

Pro-Tumor Necrosis Factor-α Processing Activity Is Tightly Controlled by a Component That Does Not Affect Notch Processing

1998 • 88 citations

Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain

1998 • 88 citations

Metalloproteinase-mediated release of the ectodomain of L1 adhesion molecule

1999 • 87 citations

Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta.

1999 • 84 citations

Cutting Edge: A Dominant Negative Form of TNF-α Converting Enzyme Inhibits ProTNF and TNFRII Secretion

1999 • 81 citations

Identification of Key Functional Amino Acids of the Mouse Fertilin β (ADAM2) Disintegrin Loop for Cell-Cell Adhesion during Fertilization

2000 • 80 citations

Netrins and netrin receptors

1999 • 77 citations

Analysis of the Roles of RGD-Binding Integrins, α4/α9 Integrins, α6 Integrins, and CD9 in the Interaction of the Fertilin β (ADAM2) Disintegrin Domain with the Mouse Egg Membrane1

2002 • 75 citations

Metalloprotease–disintegrin ADAM 12 binds to the SH3 domain of Src and activates Src tyrosine kinase in C2C12 cells

2000 • 75 citations

The Lymphocyte Metalloprotease MDC-L (ADAM 28) Is a Ligand for the Integrin α4β1

2002 • 74 citations

Catalytic activity of ADAM28

2001 • 72 citations

PACSIN2 Is a Regulator of the Metalloprotease/Disintegrin ADAM13

2000 • 70 citations

MDC-L, a Novel Metalloprotease Disintegrin Cysteine-rich Protein Family Member Expressed by Human Lymphocytes

1999 • 70 citations

Trafficking of Human ADAM 12-L: Retention in the trans-Golgi Network

2000 • 69 citations

Isolation of Two Novel Metalloproteinase-Disintegrin (ADAM) cDNAs That Show Testis-Specific Gene Expression

1999 • 65 citations

IMPLICATION OF TNF-α CONVERTASE (TACE/ADAM17) IN INDUCIBLE NITRIC OXIDE SYNTHASE EXPRESSION AND INFLAMMATION IN AN EXPERIMENTAL MODEL OF COLITIS

2001 • 64 citations

Human Metalloprotease-Disintegrin Kuzbanian Regulates Sympathoadrenal Cell Fate in Development and Neoplasia

1998 • 64 citations

ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-α

1998 • 62 citations

Meltrin α cytoplasmic domain interacts with SH3 domains of Src and Grb2 and is phosphorylated by v-Src

2000 • 61 citations

Disintegrin-like/Cysteine-Rich Region of ADAM 12 Is an Active Cell Adhesion Domain

1999 • 60 citations

Intracellular Activation of Human Adamalysin 19/Disintegrin and Metalloproteinase 19 by Furin Occurs via One of the Two Consecutive Recognition Sites

2002 • 60 citations

Human metalloprotease/disintegrin-like (MDC) gene: exon-intron organization and alternative splicing

1995 • 59 citations

Evidence for an interaction of the metalloprotease–disintegrin tumour necrosis factor α convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease–disintegrin MDC9 with a novel MAD2-related protein, MAD2β

1999 • 53 citations

Structure−Activity Relationship of Hydroxamate-Based Inhibitors on the Secretases that Cleave the Amyloid Precursor Protein, Angiotensin Converting Enzyme, CD23, and Pro-Tumor Necrosis Factor-α

2002 • 52 citations

β-Aryl-Succinic Acid Hydroxamates as Dual Inhibitors of Matrix Metalloproteinases and Tumor Necrosis Factor Alpha Converting Enzyme

2002 • 51 citations

Direct Interaction between the Cytoplasmic Tail of ADAM 12 and the Src Homology 3 Domain of p85α Activates Phosphatidylinositol 3-Kinase in C2C12 Cells

2001 • 51 citations

Skeletal muscle cell hypertrophy induced by inhibitors of metalloproteases; myostatin as a potential mediator

2001 • 48 citations

Regulation of Alzheimer β-amyloid precursor trafficking and metabolism11Portions of this review have previously appeared in Trends in Endocrinology and Metabolism and are reprinted here with the permission of Elsevier Publishing.

2000 • 42 citations

Analysis for transcript expression of meltrin alpha in normal, regenerating, and denervated rat muscle.

2000 • 41 citations

Metalloprotease-disintegrin ADAM 12 interacts with α-actinin-1

2001 • 41 citations

Molecular Cloning of the Human Fertilin β Subunit

1996 • 39 citations

The identification of seven metalloproteinase-disintegrin (ADAM) genes from genomic libraries

1999 • 39 citations

Human tMDC III: a sperm protein with a potential role in oocyte recognition

2002 • 23 citations

Cloning and Characterization of a Complementary DNA Encoding a Human Epididymis-Associated Disintegrin and Metalloprotease 7 Protein1

2001 • 23 citations

A novel metalloproteinase originally isolated from brain myelin membranes is present in many tissues

1990 • 22 citations

Expression of meltrin-α mRNA is not restricted to fusagenic cells

1997 • 22 citations

Molecular Cloning and Mapping of a Novel ADAM Gene (ADAM29) to Human Chromosome 4

1999 • 21 citations

The Specific Expression of Three Novel Splice Variant Forms of Human Metalloprotease‐like Disintegrin‐like Cysteine‐rich Protein 2 Gene in Brain Tissues and Glioma

2000 • 19 citations

Endogenous Meltrin Is Ubiquitously Expressed and Associated with the Plasma Membrane but Exogenous Meltrin Is Retained in the Endoplasmic Reticulum

2000 • 17 citations

Spontaneous Propeptide Processing of Mini-Stromelysin-1 Mutants Blocked by APMA ((4-Aminophenyl)mercuric Acetate)

1998 • 6 citations

Deleted Work

1955 • 0 citations

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