The ADAMs family of metalloproteases: multidomain proteins with multiple functions
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Abstract
References (199)
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
1997 • 3,094 citations
The Biology of Chemokines and their Receptors
2000 • 2,416 citations
Tissue inhibitors of metalloproteinases: evolution, structure and function
2000 • 1,873 citations
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
2001 • 1,715 citations
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
1997 • 1,608 citations
An Essential Role for Ectodomain Shedding in Mammalian Development
1998 • 1,607 citations
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
1999 • 1,484 citations
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
1996 • 1,473 citations
Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype
1995 • 1,457 citations
The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.
1990 • 1,423 citations
Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease
1999 • 1,115 citations
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
2002 • 1,108 citations
A Novel Proteolytic Cleavage Involved in Notch Signaling
2000 • 1,080 citations
Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor
1995 • 1,035 citations
Strain-Dependent Epithelial Defects in Mice Lacking the EGF Receptor
1995 • 1,016 citations
Notch Signaling: From the Outside In
2000 • 958 citations
The selecting: vascular adhesion molecules
1995 • 954 citations
Seven-transmembrane-spanning receptors and heart function
2002 • 926 citations
Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor
1998 • 922 citations
Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
2002 • 846 citations
A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1
2000 • 841 citations
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10
2001 • 788 citations
Development of Matrix Metalloproteinase Inhibitors in Cancer Therapy
2001 • 788 citations
Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins
1997 • 782 citations
Families of zinc metalloproteases
1994 • 769 citations
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
2002 • 727 citations
The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases
1995 • 691 citations
A potential fusion peptide and an integrin ligand domain in a protein active in sperm–egg fusion
1992 • 680 citations
The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis
2001 • 677 citations
MEMBRANE-ANCHORED GROWTH FACTORS
1993 • 676 citations
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 • 659 citations
The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts
2002 • 657 citations
Tumor Necrosis Factor-α-converting Enzyme (ADAM17) Mediates the Cleavage and Shedding of Fractalkine (CX3CL1)
2001 • 623 citations
Epidermal growth factor receptors: critical mediators of multiple receptor pathways
1999 • 610 citations
The ADAM gene family: surface proteins with adhesion and protease activity
2000 • 582 citations
Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding
1999 • 558 citations
Determination of protease cleavage site motifs using mixture-based oriented peptide libraries
2001 • 547 citations
A metalloprotease-disintegrin, MDC9/meltrin-gamma /ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor
1998 • 523 citations
Regulated Cleavage of a Contact-Mediated Axon Repellent
2000 • 522 citations
Kuzbanian Controls Proteolytic Processing of Notch and Mediates Lateral Inhibition during Drosophila and Vertebrate Neurogenesis
1997 • 516 citations
Fertilization Defects in Sperm from Mice Lacking Fertilin β
1998 • 497 citations
Functional Analysis of the Domain Structure of Tumor Necrosis Factor-α Converting Enzyme
2000 • 496 citations
TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5)
2001 • 493 citations
A metalloprotease-disintegrin participating in myoblast fusion
1995 • 492 citations
Mouse egg integrin α6β1functions as a sperm receptor
1995 • 472 citations
ADAMs: focus on the protease domain
1998 • 472 citations
Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
1997 • 456 citations
Tumor Necrosis Factor-α Converting Enzyme (TACE) Regulates Epidermal Growth Factor Receptor Ligand Availability
2002 • 415 citations
Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian
1999 • 413 citations
Diverse Cell Surface Protein Ectodomains Are Shed by a System Sensitive to Metalloprotease Inhibitors
1996 • 404 citations
The in vitro activity of ADAM‐10 is inhibited by TIMP‐1 and TIMP‐3
2000 • 396 citations
Defining brain wiring patterns and mechanisms through gene trapping in mice
2001 • 391 citations
Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins
2001 • 385 citations
Crystal structure of the catalytic domain of human tumor necrosis factor-α-converting enzyme
1998 • 376 citations
Molecular mechanisms regulating myogenic determination and differentiation
2000 • 375 citations
Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion.
1987 • 368 citations
Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells
2002 • 354 citations
Intracellular maturation and localization of the tumour necrosis factor α convertase (TACE)
2000 • 350 citations
Tumor necrosis factor-α converting enzyme
2002 • 341 citations
ADAMTS: a novel family of extracellular matrix proteases
2001 • 339 citations
KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis
1996 • 331 citations
Protein Kinase C-dependent α-Secretase Competes with β-Secretase for Cleavage of Amyloid-β Precursor Protein in the Trans-Golgi Network
2000 • 320 citations
The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein–coupled receptors
2002 • 318 citations
A Novel, Secreted Form of Human ADAM 12 (Meltrin α) Provokes Myogenesis in Vivo
1998 • 315 citations
Metalloprotease-Disintegrin MDC9: Intracellular Maturation and Catalytic Activity
1999 • 312 citations
Tumor Necrosis Factor-α-converting Enzyme Is Required for Cleavage of erbB4/HER4
2000 • 310 citations
ADAM 12-S Cleaves IGFBP-3 and IGFBP-5 and Is Inhibited by TIMP-3
2000 • 309 citations
Extracellular Signal-regulated Kinase Phosphorylates Tumor Necrosis Factor α-converting Enzyme at Threonine 735: A Potential Role in Regulated Shedding
2002 • 296 citations
Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme
1995 • 289 citations
Neutrophil rolling altered by inhibition of L-selectin shedding in vitro
1996 • 285 citations
The Disintegrins ADAM10 and TACE Contribute to the Constitutive and Phorbol Ester-regulated Normal Cleavage of the Cellular Prion Protein
2001 • 285 citations
Neuregulin, a factor with many functions in the life of a Schwann cell
2000 • 282 citations
Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein
1999 • 260 citations
Analysis of Loss of Adhesive Function in Sperm Lacking Cyritestin or Fertilin β
2001 • 258 citations
Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades
1999 • 248 citations
The Cysteine-Rich Domain of Human Adam 12 Supports Cell Adhesion through Syndecans and Triggers Signaling Events That Lead to β1 Integrin–Dependent Cell Spreading
2000 • 246 citations
Regulation of the α‐secretase ADAM10 by its prodomain and proprotein convertases
2001 • 232 citations
kuzbanian-mediated cleavage of Drosophila Notch
2002 • 226 citations
Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin α6β1: Implications for murine fertilization
1999 • 223 citations
Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence.
1990 • 219 citations
Specific Interaction of the Recombinant Disintegrin-like Domain of MDC-15 (Metargidin, ADAM-15) with Integrin αvβ3
1998 • 214 citations
Insulin-Like Growth Factor Binding Proteins: New Proteins, New Functions
1999 • 213 citations
MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.
1996 • 213 citations
RGD-independent Binding of Integrin α9β1 to the ADAM-12 and -15 Disintegrin Domains Mediates Cell-Cell Interaction
2000 • 211 citations
Cysteine-Rich Domain of Human ADAM 12 (Meltrin α) Supports Tumor Cell Adhesion
1999 • 209 citations
Mice Lacking the Metalloprotease-Disintegrin MDC9 (ADAM9) Have No Evident Major Abnormalities during Development or Adult Life
2002 • 209 citations
Calmodulin Regulates L-Selectin Adhesion Molecule Expression and Function through a Protease-Dependent Mechanism
1998 • 204 citations
Identification and Characterization of a Pro-tumor Necrosis Factor-α-processing Enzyme from the ADAM Family of Zinc Metalloproteases
1997 • 204 citations
Interaction of metargidin (ADAM-15) with αvβ3 and α5β1 integrins on different haemopoietic cells
1999 • 193 citations
Meltrin γ (ADAM-9) mediates cellular adhesion through α6β1 integrin, leading to a marked induction of fibroblast cell motility
2000 • 190 citations
Human ADAM 12 (Meltrin α) Is an Active Metalloprotease
1998 • 188 citations
Role of Src Kinases in the ADAM-mediated Release of L1 Adhesion Molecule from Human Tumor Cells
2000 • 186 citations
The Shedding of Membrane-anchored Heparin-binding Epidermal-like Growth Factor Is Regulated by the Raf/Mitogen-activated Protein Kinase Cascade and by Cell Adhesion and Spreading
1999 • 185 citations
The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila
1996 • 183 citations
Interaction of the Metalloprotease Disintegrins MDC9 and MDC15 with Two SH3 Domain-containing Proteins, Endophilin I and SH3PX1
1999 • 182 citations
ADAM 12, a Disintegrin Metalloprotease, Interacts with Insulin-like Growth Factor-binding Protein-3
2000 • 182 citations
Roles of Meltrin β/ADAM19 in the Processing of Neuregulin
2001 • 181 citations
Reactive oxygen species mediate tumor necrosis factor alpha‐converting, enzyme‐dependent ectodomain shedding induced by phorbol myristate acetate
2000 • 180 citations
Coordinated Expression of β‐Amyloid Precursor Protein and the Putative β‐Secretase BACE and α‐Secretase ADAM10 in Mouse and Human Brain
2000 • 179 citations
Normal Fertilization Occurs with Eggs Lacking the Integrin α6β1 and Is Cd9-Dependent
2000 • 178 citations
Heparin-binding EGF-like growth factor
1997 • 172 citations
Metargidin, a Membrane-anchored Metalloprotease-Disintegrin Protein with an RGD Integrin Binding Sequence
1996 • 170 citations
Shedding of interleukin-6 receptor and tumor necrosis factor α
2000 • 168 citations
Intracellular Maturation of the Mouse Metalloprotease Disintegrin MDC15
1998 • 167 citations
Function of an Axonal Chemoattractant Modulated by Metalloprotease Activity
2000 • 165 citations
Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration
2001 • 162 citations
Functional Classification of ADAMs Based on a Conserved Motif for Binding to Integrin α9β1
2002 • 159 citations
The Metalloprotease Disintegrin ADAM8
2002 • 159 citations
TACE and other ADAM proteases as targets for drug discovery
2001 • 156 citations
Specific Sequence Elements Are Required for the Expression of Functional Tumor Necrosis Factor-α-converting Enzyme (TACE)
1999 • 156 citations
SUP-17, a Caenorhabditis elegans ADAM protein related to Drosophila KUZBANIAN, and its role in LIN-12/NOTCH signalling
1997 • 155 citations
Binding of ADAM12, a Marker of Skeletal Muscle Regeneration, to the Muscle-specific Actin-binding Protein, α-Actinin-2, Is Required for Myoblast Fusion
2000 • 154 citations
Characterization of the Binding of Recombinant Mouse Sperm Fertilin β Subunit to Mouse Eggs: Evidence for Adhesive Activity via an Egg β1Integrin-Mediated Interaction
1997 • 153 citations
The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs
1997 • 152 citations
TNF-α-Converting Enzyme Cleaves the Macrophage Colony-Stimulating Factor Receptor in Macrophages Undergoing Activation
2001 • 150 citations
Fertilin β and other ADAMs as integrin ligands: insights into cell adhesion and fertilization
2001 • 145 citations
Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism.
1995 • 144 citations
The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs
2002 • 144 citations
Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-α converting enzyme
2001 • 143 citations
Refined 2·0 Å X-ray Crystal Structure of the Snake Venom Zinc-endopeptidase Adamalysin II
1994 • 142 citations
Distinctive effects of the viral oncogenes myc, erb, fps, and src on the differentiation program of quail myogenic cells.
1985 • 141 citations
Structure, function and evolutionary relationship of proteins containing a disintegrin domain
1992 • 138 citations
Shedding light on sheddases: role in growth and development
2002 • 134 citations
Biochemical and Pharmacological Criteria Define Two Shedding Activities for TRANCE/OPGL That Are Distinct from the Tumor Necrosis Factor α Convertase
2001 • 133 citations
Purification of ADAM 10 from bovine spleen as a TNFα convertase
1997 • 133 citations
Metalloprotease-dependent Protransforming Growth Factor-α Ectodomain Shedding in the Absence of Tumor Necrosis Factor-α-converting Enzyme
2001 • 133 citations
TNF-alpha convertase enzyme from human arthritis-affected cartilage: isolation of cDNA by differential display, expression of the active enzyme, and regulation of TNF-alpha.
1998 • 130 citations
Transendothelial migration of lymphocytes across high endothelial venules into lymph nodes is affected by metalloproteinases
2001 • 130 citations
Multiple signals activate cleavage of the membrane transforming growth factor-alpha precursor.
1991 • 129 citations
Phosphorylation-dependent Interactions between ADAM15 Cytoplasmic Domain and Src Family Protein-tyrosine Kinases
2002 • 128 citations
Tissue Inhibitor of Metalloproteinases-3 Inhibits Shedding of L-selectin from Leukocytes
1999 • 126 citations
Regulation of Human ADAM 12 Protease by the Prodomain
1999 • 125 citations
Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28
2000 • 123 citations
Sequence-Specific Interaction between the Disintegrin Domain of Mouse ADAM 3 and Murine Eggs: Role of β1 Integrin-associated Proteins CD9, CD81, and CD98
2001 • 122 citations
The Metallo-Disintegrin ADAM10 (MADM) from Bovine Kidney Has Type IV Collagenase Activityin Vitro
1998 • 121 citations
Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity
2002 • 121 citations
Role of the Juxtamembrane Domains of the Transforming Growth Factor-α Precursor and the β-Amyloid Precursor Protein in Regulated Ectodomain Shedding
1997 • 120 citations
Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin-binding EGF-like growth factor independently of protein kinase C
1998 • 119 citations
The Role of ADAM 15 in Glomerular Mesangial Cell Migration
2002 • 117 citations
Constitutive Proteolysis of the ErbB-4 Receptor Tyrosine Kinase by a Unique, Sequential Mechanism
1997 • 117 citations
Cell Volume-dependent Regulation of L-selectin Shedding in Neutrophils
1999 • 115 citations
ADAM 23/MDC3, a Human Disintegrin That Promotes Cell Adhesion via Interaction with the αvβ3 Integrin through an RGD-independent Mechanism
2000 • 115 citations
Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase
2014 • 112 citations
New Type of Metalloproteinase Inhibitor: Design and Synthesis of New Phosphonamide-Based Hydroxamic Acids
2002 • 110 citations
Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes: functional consequences for neutrophil aggregation.
1996 • 106 citations
Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase
2001 • 105 citations
CD156 (Human ADAM8): Expression, Primary Amino Acid Sequence, and Gene Location
1997 • 104 citations
Spatially- and temporally-restricted expression of meltrin α (ADAM12) and β (ADAM19) in mouse embryo
1998 • 102 citations
Expression of Members of the Novel Membrane Linked Metalloproteinase Family ADAM in Cells Derived from a Range of Haematological Malignancies
1997 • 102 citations
Cutting edge: a dominant negative form of TNF-alpha converting enzyme inhibits proTNF and TNFRII secretion.
1999 • 101 citations
Sequence-specific Interaction between the Disintegrin Domain of Mouse ADAM 2 (Fertilin β) and Murine Eggs
2000 • 100 citations
TNF-α Convertase Enzyme from Human Arthritis-Affected Cartilage: Isolation of cDNA by Differential Display, Expression of the Active Enzyme, and Regulation of TNF-α
1998 • 99 citations
Evidence that Distinct States of the Integrin α6β1 Interact with Laminin and an ADAM
1999 • 96 citations
A secreted form of human ADAM9 has an α-secretase activity for APP
2002 • 96 citations
L-selectin shedding does not regulate human neutrophil attachment, rolling, or transmigration across human vascular endothelium in vitro.
1997 • 92 citations
New α-Substituted Succinate-Based Hydroxamic Acids as TNFα Convertase Inhibitors
1999 • 90 citations
The role of cell adhesion molecule L1 in axonal extension, growth cone motility, and signal transduction
1997 • 89 citations
ADAM13 Disintegrin and Cysteine-rich Domains Bind to the Second Heparin-binding Domain of Fibronectin
2002 • 89 citations
Pro-Tumor Necrosis Factor-α Processing Activity Is Tightly Controlled by a Component That Does Not Affect Notch Processing
1998 • 88 citations
Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain
1998 • 88 citations
Metalloproteinase-mediated release of the ectodomain of L1 adhesion molecule
1999 • 87 citations
Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta.
1999 • 84 citations
Cutting Edge: A Dominant Negative Form of TNF-α Converting Enzyme Inhibits ProTNF and TNFRII Secretion
1999 • 81 citations
Identification of Key Functional Amino Acids of the Mouse Fertilin β (ADAM2) Disintegrin Loop for Cell-Cell Adhesion during Fertilization
2000 • 80 citations
Netrins and netrin receptors
1999 • 77 citations
Analysis of the Roles of RGD-Binding Integrins, α4/α9 Integrins, α6 Integrins, and CD9 in the Interaction of the Fertilin β (ADAM2) Disintegrin Domain with the Mouse Egg Membrane1
2002 • 75 citations
Metalloprotease–disintegrin ADAM 12 binds to the SH3 domain of Src and activates Src tyrosine kinase in C2C12 cells
2000 • 75 citations
The Lymphocyte Metalloprotease MDC-L (ADAM 28) Is a Ligand for the Integrin α4β1
2002 • 74 citations
Catalytic activity of ADAM28
2001 • 72 citations
PACSIN2 Is a Regulator of the Metalloprotease/Disintegrin ADAM13
2000 • 70 citations
MDC-L, a Novel Metalloprotease Disintegrin Cysteine-rich Protein Family Member Expressed by Human Lymphocytes
1999 • 70 citations
Trafficking of Human ADAM 12-L: Retention in the trans-Golgi Network
2000 • 69 citations
Isolation of Two Novel Metalloproteinase-Disintegrin (ADAM) cDNAs That Show Testis-Specific Gene Expression
1999 • 65 citations
IMPLICATION OF TNF-α CONVERTASE (TACE/ADAM17) IN INDUCIBLE NITRIC OXIDE SYNTHASE EXPRESSION AND INFLAMMATION IN AN EXPERIMENTAL MODEL OF COLITIS
2001 • 64 citations
Human Metalloprotease-Disintegrin Kuzbanian Regulates Sympathoadrenal Cell Fate in Development and Neoplasia
1998 • 64 citations
ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-α
1998 • 62 citations
Meltrin α cytoplasmic domain interacts with SH3 domains of Src and Grb2 and is phosphorylated by v-Src
2000 • 61 citations
Disintegrin-like/Cysteine-Rich Region of ADAM 12 Is an Active Cell Adhesion Domain
1999 • 60 citations
Intracellular Activation of Human Adamalysin 19/Disintegrin and Metalloproteinase 19 by Furin Occurs via One of the Two Consecutive Recognition Sites
2002 • 60 citations
Human metalloprotease/disintegrin-like (MDC) gene: exon-intron organization and alternative splicing
1995 • 59 citations
Evidence for an interaction of the metalloprotease–disintegrin tumour necrosis factor α convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease–disintegrin MDC9 with a novel MAD2-related protein, MAD2β
1999 • 53 citations
Structure−Activity Relationship of Hydroxamate-Based Inhibitors on the Secretases that Cleave the Amyloid Precursor Protein, Angiotensin Converting Enzyme, CD23, and Pro-Tumor Necrosis Factor-α
2002 • 52 citations
β-Aryl-Succinic Acid Hydroxamates as Dual Inhibitors of Matrix Metalloproteinases and Tumor Necrosis Factor Alpha Converting Enzyme
2002 • 51 citations
Direct Interaction between the Cytoplasmic Tail of ADAM 12 and the Src Homology 3 Domain of p85α Activates Phosphatidylinositol 3-Kinase in C2C12 Cells
2001 • 51 citations
Skeletal muscle cell hypertrophy induced by inhibitors of metalloproteases; myostatin as a potential mediator
2001 • 48 citations
Regulation of Alzheimer β-amyloid precursor trafficking and metabolism11Portions of this review have previously appeared in Trends in Endocrinology and Metabolism and are reprinted here with the permission of Elsevier Publishing.
2000 • 42 citations
Analysis for transcript expression of meltrin alpha in normal, regenerating, and denervated rat muscle.
2000 • 41 citations
Metalloprotease-disintegrin ADAM 12 interacts with α-actinin-1
2001 • 41 citations
Molecular Cloning of the Human Fertilin β Subunit
1996 • 39 citations
The identification of seven metalloproteinase-disintegrin (ADAM) genes from genomic libraries
1999 • 39 citations
Human tMDC III: a sperm protein with a potential role in oocyte recognition
2002 • 23 citations
Cloning and Characterization of a Complementary DNA Encoding a Human Epididymis-Associated Disintegrin and Metalloprotease 7 Protein1
2001 • 23 citations
A novel metalloproteinase originally isolated from brain myelin membranes is present in many tissues
1990 • 22 citations
Expression of meltrin-α mRNA is not restricted to fusagenic cells
1997 • 22 citations
Molecular Cloning and Mapping of a Novel ADAM Gene (ADAM29) to Human Chromosome 4
1999 • 21 citations
The Specific Expression of Three Novel Splice Variant Forms of Human Metalloprotease‐like Disintegrin‐like Cysteine‐rich Protein 2 Gene in Brain Tissues and Glioma
2000 • 19 citations
Endogenous Meltrin Is Ubiquitously Expressed and Associated with the Plasma Membrane but Exogenous Meltrin Is Retained in the Endoplasmic Reticulum
2000 • 17 citations
Spontaneous Propeptide Processing of Mini-Stromelysin-1 Mutants Blocked by APMA ((4-Aminophenyl)mercuric Acetate)
1998 • 6 citations
Deleted Work
1955 • 0 citations