Human ADAM 12 (Meltrin α) Is an Active Metalloprotease

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

1997 • 3,094 citations

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

1997 • 1,608 citations

Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.

1997 • 1,510 citations

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

1990 • 1,423 citations

Proteolytic remodeling of extracellular matrix

1995 • 1,086 citations

[13] Evolutionary families of metallopeptidases

1995 • 794 citations

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation.

1990 • 699 citations

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

1995 • 620 citations

Hemorrhagic metalloproteinases from snake venoms

1994 • 618 citations

Kuzbanian Controls Proteolytic Processing of Notch and Mediates Lateral Inhibition during Drosophila and Vertebrate Neurogenesis

1997 • 516 citations

ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions.

1995 • 507 citations

A metalloprotease-disintegrin participating in myoblast fusion

1995 • 492 citations

Molecular Cloning of a Gene Encoding a New Type of Metalloproteinase-disintegrin Family Protein with Thrombospondin Motifs as an Inflammation Associated Gene

1997 • 480 citations

Metalloprotease-Disintegrins: Links to Cell Adhesion and Cleavage of TNFα and Notch

1997 • 363 citations

KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis

1996 • 331 citations

Purification, cloning, and molecular characterization of a high molecular weight hemorrhagic metalloprotease, jararhagin, from Bothrops jararaca venom. Insights into the disintegrin gene family

1992 • 325 citations

A Novel, Secreted Form of Human ADAM 12 (Meltrin α) Provokes Myogenesis in Vivo

1998 • 315 citations

[21] Snake venom metalloendopeptidases: Reprolysins

1995 • 278 citations

ADAMs in Fertilization and Development

1996 • 259 citations

cDNA Sequences for Four Snake Venom Metalloproteinases: Structure, Classification, and Their Relationship to Mammalian Reproductive Proteins

1994 • 239 citations

Zinc Metalloproteases In Health And Disease

1996 • 210 citations

Identification and Characterization of a Pro-tumor Necrosis Factor-α-processing Enzyme from the ADAM Family of Zinc Metalloproteases

1997 • 204 citations

Snake venom metalloproteinases: Structure, function and relationship to the ADAMs family of proteins

1996 • 184 citations

The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila

1996 • 183 citations

ADAMs and cell fusion

1996 • 143 citations

Purification of ADAM 10 from bovine spleen as a TNFα convertase

1997 • 133 citations

Molecular cloning of MADM: a catalytically active mammalian disintegrin-metalloprotease expressed in various cell types

1996 • 121 citations

Activation of snake venom metalloproteinases by a cysteine switch‐like mechanism

1993 • 118 citations

Sequence requirements for precursor cleavage within the constitutive secretory pathway.

1992 • 113 citations

Proteolytic and non-proteolytic activation of human neutrophil progelatinase B

1995 • 102 citations

Mutational analysis of the transin (rat stromelysin) autoinhibitor region demonstrates a role for residues surrounding the “cysteine switch”

1991 • 99 citations

Furin/PACE/SPC1: A convertase involved in exocytic and endocytic processing of precursor proteins

1996 • 70 citations

Identification of Metalloprotease/Disintegrins inXenopus laevisTestis with a Potential Role in Fertilization

1997 • 69 citations

Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway

1993 • 66 citations

APMA (4-Aminophenylmercuric Acetate) Activation of Stromelysin-1 Involves Protein Interactions in Addition to Those with Cysteine-75 in the Propeptide

1996 • 64 citations

Disruption of the cysteine-75 and zinc ion coordination is not sufficient to activate the precursor of human matrix metalloproteinase 3 (stromelysin 1)

1993 • 58 citations

Interaction of α₂‐Macroglobulin with Matrix Metalloproteinases and Its Use for Identification of Their Active Forms^a

1994 • 57 citations

The Proteinase‐Binding Reaction of α₂M

1994 • 29 citations

Proteolytic processing of the α-subunit of rat endopeptidase-24.18 by furin

1995 • 21 citations

Role of Internal Thiol Esters in the α‐Macroglobulin‐Proteinase Binding Mechanism^a

1994 • 21 citations