Mouse egg integrin α6β1functions as a sperm receptor

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

The Physiology of Reproduction

1988 • 7,765 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Membrane Fusion

1990 • 2,458 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes

1990 • 1,592 citations

Integrins.

1991 • 1,369 citations

Physiology of Reproduction

2000 • 1,184 citations

Integrin cytoplasmic domains mediate inside-out signal transduction

1994 • 682 citations

A potential fusion peptide and an integrin ligand domain in a protein active in sperm–egg fusion

1992 • 680 citations

Laminin receptor on platelets is the integrin VLA-6

1988 • 679 citations

Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo.

1992 • 669 citations

Membrane Fusion

1992 • 613 citations

A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin.

1985 • 517 citations

Disintegrins: A Family of Integrin Inhibitory Proteins from Viper Venoms

1990 • 497 citations

Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling

1993 • 447 citations

ADAM, a Widely Distributed and Developmentally Regulated Gene Family Encoding Membrane Proteins with A̱Ḏisintegrin A̱nd M̱etalloprotease Domain

1995 • 406 citations

Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion.

1987 • 368 citations

Profile of a mammalian sperm receptor1,2

1990 • 367 citations

A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

1989 • 352 citations

Developmental regulation of integrin expression at the time of implantation in the mouse embryo

1993 • 321 citations

A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.

1989 • 314 citations

The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrin.

1990 • 288 citations

Association of the VLA a Subunit with a Novel Protein

1989 • 285 citations

Kalinin is more efficient than laminin in promoting adhesion of primary keratinocytes and some other epithelial cells and has a different requirement for integrin receptors.

1994 • 252 citations

Solution Structure of Kistrin, a Potent Platelet Aggregation Inhibitor and GP IIb-IIIa Antagonist

1991 • 251 citations

Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion.

1994 • 241 citations

cDNA Sequences for Four Snake Venom Metalloproteinases: Structure, Classification, and Their Relationship to Mammalian Reproductive Proteins

1994 • 239 citations

Structural domains in venom proteins: Evidence that metalloproteinases and nonenzymatic platelet aggregation inhibitors (disintegrins) from snake venoms are derived by proteolysis from a common precursor

1992 • 237 citations

The α6β1 (VLA-6) and α6β4 protein complexes: tissue distribution and biochemical properties

1990 • 219 citations

Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence.

1990 • 219 citations

Three-dimensional structure of echistatin, the smallest active RGD protein

1991 • 199 citations

Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains.

1991 • 197 citations

Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures.

1988 • 186 citations

Molecular cloning of the human α6 integrin subunit

1991 • 183 citations

The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications.

1993 • 182 citations

Integrin, A Transmembrane Glycoprotein Complex Mediating Cell-Substratum Adhesion

1987 • 176 citations

Sea Urchin Egg Receptor for Sperm: Sequence Similarity of Binding Domain and hsp70

1993 • 164 citations

Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation.

1991 • 160 citations

Integrin heterodimer and receptor complexity in avian and mammalian cells.

1989 • 156 citations

An improved culture medium for mouse blastocysts

1980 • 146 citations

A 28-kDa Protein with Disintegrin-like Structure (Jararhagin-C) Purified from Bothrops jararaca Venom Inhibits Collagen- and ADP-Induced Platelet Aggregation

1994 • 142 citations

Evidence that an Arg-Gly-Asp Adhesion Sequence Plays a Role in Mammalian Fertilization

1990 • 140 citations

Molecular Mechanisms of Sperm-Egg Membrane Binding and Fusion in Mammals

1993 • 139 citations

Structure, function and evolutionary relationship of proteins containing a disintegrin domain

1992 • 138 citations

Expression of β1 integrin complexes on the surface of unfertilized mouse oocyte

1993 • 127 citations

Integrin Receptor α6β1 is Localized at Specific Sites of Cell-to-Cell Contact in Rat Seminiferous Epithelium1

1995 • 126 citations

Integrin alpha v beta 8. Interaction with vitronectin and functional divergence of the beta 8 cytoplasmic domain.

1994 • 122 citations

Expression and function of the cytoplasmic variants of the integrin alpha 6 subunit in transfected K562 cells. Activation-dependent adhesion and interaction with isoforms of laminin.

1993 • 117 citations

Expression of syndecan, a putative low affinity fibroblast growth factor receptor, in the early mouse embryo

1991 • 115 citations

Variants of the α₆β₁Laminin Receptor in Early Murine Development: Distribution, Molecular Cloning and Chromosomal Localization of the Mouse Integrin α₆Subunit

1993 • 108 citations

Mammalian oocytes exhibit specific recognition of the RGD (ARG‐Gly‐Asp) tripeptide and express oolemmal integrins

1993 • 97 citations

Inside-out integrin signaling in macrophages. Analysis of the role of the alpha 6A beta 1 and alpha 6B beta 1 integrin variants in laminin adhesion by cDNA expression in an alpha 6 integrin-deficient macrophage cell line

1993 • 86 citations

Evaluation of mouse sperm acrosomal status and viability by flow cytometry

1993 • 80 citations

Pre-loading of mouse oocytes with DNA-specific fluorochrome (Hoechst 33342) permits rapid detection of sperm-oocyte fusion

1988 • 73 citations

Targeted deletion of beta 1 integrins in F9 embryonal carcinoma cells affects morphological differentiation but not tissue-specific gene expression.

1993 • 73 citations

Suppression of mouse melanoma metastasis by EA-1, a monoclonal antibody specific for alpha 6 integrins.

1993 • 73 citations

Laminin binding proteins

1991 • 72 citations

Regulation of cellular interactions with laminin by integrin cytoplasmic domains: the A and B structural variants of the alpha 6 beta 1 integrin differentially modulate the adhesive strength, morphology, and migration of macrophages.

1994 • 68 citations

Integrins : molecular and biological responses to the extracellular matrix

1994 • 66 citations

Suppression of Mouse Melanoma Metastasis by EA-1, A Monoclonal Antibody Specific for α6 Integrins

1993 • 55 citations

Male Germ Cell‐Expressed Mouse Gene TAZ83 Encodes a Putative, Cysteine‐rich Transmembrane Protein (cyritestin) Sharing Homologies with Snake Toxins and Sperm‐Egg Fusion Proteins

1994 • 52 citations

Acrosome reaction induced by immunoaggregation of a proteinase inhibitor bound to the murine sperm head

1991 • 44 citations

Initial evaluation of fertilin as an immunocontraceptive antigen and molecular cloning of the cynomolgus monkey fertilin β subunit

1996 • 42 citations

Integrins: Molecular and biological responses to the extracellular matrix

1995 • 22 citations

Fertilization of the mouse oocyte

1991 • 21 citations

Integrins in Development

1994 • 15 citations