Back to search

The ADAM gene family: surface proteins with adhesion and protease activity

Data up to Jan 2025

Published2000
Citations582
References47

Total Citations Per Year

Abstract

References (47)

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

1997 • 3,094 citations

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

1997 • 1,608 citations

An Essential Role for Ectodomain Shedding in Mammalian Development

1998 • 1,607 citations

Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease

1999 • 1,115 citations

Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor

1998 • 922 citations

A potential fusion peptide and an integrin ligand domain in a protein active in sperm–egg fusion

1992 • 680 citations

Membrane protein secretases

1997 • 634 citations

VIRUS-CELL AND CELL-CELL FUSION

1996 • 559 citations

A metalloprotease-disintegrin, MDC9/meltrin-gamma /ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor

1998 • 523 citations

Kuzbanian Controls Proteolytic Processing of Notch and Mediates Lateral Inhibition during Drosophila and Vertebrate Neurogenesis

1997 • 516 citations

Fertilization Defects in Sperm from Mice Lacking Fertilin β

1998 • 497 citations

A metalloprotease-disintegrin participating in myoblast fusion

1995 • 492 citations

Cloning and Characterization of ADAMTS11 , an Aggrecanase from the ADAMTS Family

1999 • 485 citations

Mouse egg integrin α6β1functions as a sperm receptor

1995 • 472 citations

ADAMs: focus on the protease domain

1998 • 472 citations

Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian

1999 • 413 citations

Crystal structure of the catalytic domain of human tumor necrosis factor-α-converting enzyme

1998 • 376 citations

Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion.

1987 • 368 citations

Metalloprotease-Disintegrins: Links to Cell Adhesion and Cleavage of TNFα and Notch

1997 • 363 citations

KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis

1996 • 331 citations

A Novel, Secreted Form of Human ADAM 12 (Meltrin α) Provokes Myogenesis in Vivo

1998 • 315 citations

Metalloprotease-Disintegrin MDC9: Intracellular Maturation and Catalytic Activity

1999 • 312 citations

Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion.

1994 • 241 citations

A Role for the Disintegrin Domain of Cyritestin, a Sperm Surface Protein Belonging to the ADAM Family, in Mouse Sperm–Egg Plasma Membrane Adhesion and Fusion

1997 • 235 citations

Specific Interaction of the Recombinant Disintegrin-like Domain of MDC-15 (Metargidin, ADAM-15) with Integrin αvβ3

1998 • 214 citations

Cysteine-Rich Domain of Human ADAM 12 (Meltrin α) Supports Tumor Cell Adhesion

1999 • 209 citations

Disintegrins and other naturally occurring antagonists of platelet fibrinogen receptors.

1994 • 206 citations

Interaction of metargidin (ADAM-15) with αvβ3 and α5β1 integrins on different haemopoietic cells

1999 • 193 citations

Human ADAM 12 (Meltrin α) Is an Active Metalloprotease

1998 • 188 citations

Control of organ shape by a secreted metalloprotease in the nematode Caenorhabditis elegans

1999 • 182 citations

Inhibition of collagen-induced platelet aggregation as the result of cleavage of α2β1-integrin by the snake venom metalloproteinase jararhagin

1996 • 169 citations

Mouse sperm-egg plasma membrane interactions: analysis of roles of egg integrins and the mouse sperm homologue of PH-30 (fertilin) β

1995 • 157 citations

Function of Disintegrin-like/Cysteine-rich Domains of Atrolysin A

1997 • 141 citations

Regulation of Human ADAM 12 Protease by the Prodomain

1999 • 125 citations

Molecular cloning of MADM: a catalytically active mammalian disintegrin-metalloprotease expressed in various cell types

1996 • 121 citations

Evidence for Distinct Serine Protease Activities with a Potential Role in Processing the Sperm Protein Fertilin

1997 • 113 citations

Mediation of sperm-egg fusion: evidence that mouse egg α6β1 integrin is the receptor for sperm fertilinβ

1999 • 108 citations

Evidence that Distinct States of the Integrin α6β1 Interact with Laminin and an ADAM

1999 • 96 citations

ADAMTS: A novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats

1999 • 86 citations

Characterization of the Binding of Recombinant Mouse Sperm Fertilin α Subunit to Mouse Eggs: Evidence for Function as a Cell Adhesion Molecule in Sperm-Egg Binding

1997 • 70 citations

Expression of the rabbit sperm protein Sp17 in cos cells and interaction of recombinant Sp17 with the rabbit zona pellucida

1995 • 68 citations

Decreased in vitro fertilization efficiencies in the presence of specific cyritestin peptides

1997 • 54 citations

A model for sperm-egg binding and fusion based on ADAMs and integrins

1997 • 48 citations

Peptides corresponding to the epidermal growth factor-like domain of mouse fertilin: Synthesis and biological activity

1998 • 11 citations

Roles of Metalloprotease-Disintegrins in Cell-Cell Interactions, in Neurogenesis, and in the Cleavage of TNFα

1999 • 5 citations

Deleted Work

1955 • 0 citations

Cited By (0)

No citing papers found in database

The ADAM gene family: surface proteins with adhesion and protease activity (2000) – Trends in Genetics | Metascience Observatory Explorer