Corticotropin Releasing Hormone and Proopiomelanocortin Involvement in the Cutaneous Response to Stress

Dermatology in General Medicine.

1987 • 4,066 citations

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

1982 • 3,896 citations

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

1998 • 1,666 citations

The Cloning of a Family of Genes That Encode the Melanocortin Receptors

1992 • 1,616 citations

Immune-Neuro-Endocrine Interactions: Facts and Hypotheses

1996 • 1,477 citations

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

1995 • 1,469 citations

Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action

1999 • 1,254 citations

Physiology and pharmacology of corticotropin-releasing factor.

1991 • 1,138 citations

Signal transduction through NF-κB

1998 • 1,103 citations

Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin

1999 • 1,000 citations

Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans

1995 • 972 citations

Expression cloning of a human corticotropin-releasing-factor receptor.

1993 • 923 citations

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1

1998 • 919 citations

Localization of novel corticotropin-releasing factor receptor (CRF2) mRNA expression to specific subcortical nuclei in rat brain: comparison with CRF1 receptor mRNA expression

1995 • 917 citations

A placental clock controlling the length of human pregnancy

1995 • 897 citations

Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function

1993 • 873 citations

A molecular basis for bidirectional communication between the immune and neuroendocrine systems.

1989 • 842 citations

Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.

1995 • 836 citations

Proopiomelanocortin Neurons Are Direct Targets for Leptin in the Hypothalamus

1997 • 731 citations

The syntax of immune-neuroendocrine communication

1994 • 720 citations

Molecular cloning of a novel melanocortin receptor.

1993 • 683 citations

Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA

1992 • 595 citations

Intraadrenal Interactions in the Regulation of Adrenocortical Steroidogenesis

1998 • 585 citations

The opiomelanotropinergic neuronal and endocrine systems

1982 • 540 citations

High endothelial venules (HEVs): specialized endothelium for lymphocyte migration

1995 • 539 citations

Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain

1993 • 536 citations

Proopiomelanocortin Processing in the Pituitary, Central Nervous System, and Peripheral Tissues

1988 • 535 citations

Hypothalamic Pro-Opiomelanocortin mRNA Is Reduced By Fasting in ob/ob and db/db Mice, but Is Stimulated by Leptin

1998 • 518 citations

Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary.

1994 • 514 citations

The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation.

1996 • 513 citations

Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart.

1995 • 497 citations

Autocrine or Paracrine Inflammatory Actions of Corticotropin-Releasing Hormone in Vivo

1991 • 485 citations

Exocrine Gland Dysfunction in MC5-R-Deficient Mice: Evidence for Coordinated Regulation of Exocrine Gland Function by Melanocortin Peptides

1997 • 477 citations

Physiology, biochemistry, and molecular biology of the skin

1991 • 434 citations

Corticotropin-Releasing Hormone Induces Skin Mast Cell Degranulation and Increased Vascular Permeability, A Possible Explanation for Its Proinflammatory Effects*

1998 • 426 citations

Regulation of Hypothalamic Proopiomelanocortin mRNA by Leptin in ob/ob Mice

1997 • 425 citations

Isolation and sequence analysis of the human corticotropin-releasing factor precursor gene.

1983 • 420 citations

Corticotrophin-releasing factor receptors: from molecular biology to drug design

1996 • 399 citations

Control and function of sebaceous glands

1989 • 382 citations

A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle.

1995 • 373 citations

Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides.

1995 • 373 citations

Corticotropin releasing factor induction of leukocyte-derived immunoreactive ACTH and endorphins

1986 • 361 citations

Cloning and characterization of the cDNAs for human and rat corticotropin releasing factor-binding proteins

1991 • 358 citations

Proopiomelanocortin-derived peptides are synthesized and released by human keratinocytes.

1994 • 341 citations

IN VITROBIOASSAY FOR THE MELANOCYTE STIMULATING HORMONE¹

1954 • 340 citations

The pigmentary system : physiology and pathophysiology

1998 • 339 citations

Evidence for local stimulation of ACTH secretion by corticotropin-releasing factor in human placenta

1987 • 334 citations

Peptide Signaling in Human Placenta and Membranes: Autocrine, Paracrine, and Endocrine Mechanisms*

1996 • 334 citations

Feeding and body-weight regulation by hypothalamic neuropeptides—mediation of the actions of leptin

1999 • 330 citations

Effect of Alpha- and Beta-Melanocyte Stimulating Hormones on the Skin Colour of Man

1961 • 328 citations

Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors

1993 • 320 citations

Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B

1996 • 320 citations

Binding of melanotropic hormones to the melanocortin receptor MC1R on human melanocytes stimulates proliferation and melanogenesis.

1996 • 313 citations

The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma

1996 • 309 citations

Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue.

1994 • 294 citations

Melanogenesis is coupled to murine anagen: Toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth

1993 • 287 citations

Corticotropin-Releasing Hormone in Humans*

1992 • 283 citations

Evidence of autocrine modulation of macrophage nitric oxide synthase by alpha-melanocyte-stimulating hormone.

1995 • 282 citations

.alpha.-Melanotropin: the minimal active sequence in the frog skin bioassay

1987 • 272 citations

The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing.

1993 • 259 citations

Molecular Identification and Analysis of a Novel Human Corticotropin-Releasing Factor (CRF) Receptor: The CRF2γ Receptor

1998 • 258 citations

Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary.

1992 • 256 citations

Melanocortin 1 Receptor Variants in an Irish Population

1998 • 252 citations

Alpha-melanocyte-stimulating hormone inhibits the nuclear transcription factor NF-kappa B activation induced by various inflammatory agents.

1998 • 245 citations

New regulators of melanin biosynthesis and the autodestruction of melanoma cells

1980 • 244 citations

Independent and Additive Effects of Central POMC and Leptin Pathways on Murine Obesity

1997 • 242 citations

Evidence Suggesting That Galanin (GAL), Melanin-Concentrating Hormone (MCH), Neurotensin (NT), Proopiomelanocortin (POMC) and Neuropeptide Y (NPY) Are Targets of Leptin Signaling in the Hypothalamus

1998 • 241 citations

Regulation of Proopiomelanocortin Gene Expression in Pituitary

1988 • 239 citations

Cloning and characterization of the human corticotropin-releasing factor-2 receptor complementary deoxyribonucleic acid.

1996 • 228 citations

Stress-induced intracranial mast cell degranulation: a corticotropin- releasing hormone-mediated effect

1995 • 225 citations

Identification of alpha-melanocyte stimulating hormone as a potential immunosuppressive factor in aqueous humor

1992 • 225 citations

Corticotropin-Releasing Hormone Directly and Preferentially Stimulates Dehydroepiandrosterone Sulfate Secretion by Human Fetal Adrenal Cortical Cells*

1998 • 223 citations

Pituitary Cytokine and Growth Factor Expression and Action

1997 • 221 citations

Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1.

1986 • 221 citations

Pro-opiomelanocortin messenger ribonucleic acid and posttranslational processing of beta endorphin in spleen macrophages.

1986 • 221 citations

Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart.

1995 • 218 citations

Rat Corticotropin-Releasing Hormone Gene: Sequence and Tissue-Specific Expression*

1987 • 217 citations

Post-Translational Processing of Proopiomelanocortin in the Pituitary and in the Brain

1997 • 211 citations

Complete amino acid sequence of mouse pro-opiomelanocortin derived from the nucleotide sequence of pro-opiomelanocortin cDNA.

1983 • 207 citations

α-Melanocyte-Stimulating Hormone Inhibits the Nuclear Transcription Factor NF-κB Activation Induced by Various Inflammatory Agents

1998 • 206 citations

Induction of Skin Tanning by Subcutaneous Administration of a Potent Synthetic Melanotropin

1991 • 205 citations

α-Melanocyte Stimulating Hormone in the Modulation of Host Reactions*

1993 • 201 citations

ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin.

1996 • 201 citations

The neuropeptide α-MSH has specific receptors on neutrophils and reduces chemotaxis in vitro

1996 • 198 citations

Pro-opiomelanocortin-derived peptides induce IL-10 production in human monocytes.

1996 • 197 citations

Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line.

1996 • 196 citations

The Results of Extirpation of the Anterior Lobe of the Hypophysis and of the Thyroid of Rana pipiens Larvæ

1916 • 196 citations

Human pigmentation genetics: the difference is only skin deep

1998 • 188 citations

Corticotropin Releasing Hormone, Receptor Regulation and the Stress Response

1998 • 188 citations

Structural organization of human genomic DNA encoding the pro-opiomelanocortin peptide.

1980 • 181 citations

Factors involved in the regulation of adrenocorticotropic hormone/beta-lipotropic hormone.

1988 • 180 citations

Characterization of Agouti-Related Protein Binding to Melanocortin Receptors

1999 • 177 citations

Agouti Signaling Protein Inhibits Melanogenesis and the Response of Human Melanocytes to α-Melanotropin

1997 • 175 citations

Characterisation of ACTH Peptides in Human Skin and Their Activation of the Melanocortin‐1 Receptor

1997 • 173 citations

Adrenocorticotrophic and melanocyte-stimulating peptides in the human pituitary

1974 • 171 citations

ACTH induces up-regulation of ACTH receptor mRNA in mouse and human adrenocortical cell lines

1994 • 170 citations

Melanogenesis During the Anagen-Catagen-Telogen Transformation of the Murine Hair Cycle

1994 • 170 citations

MSH peptides are present in mammalian skin

1983 • 161 citations

Detection of proopiomelanocortin-derived antigens in normal and pathologic human skin.

1993 • 160 citations

α-MSH production, receptors, and influence on neopterin in a human monocyte/macrophage cell line

1996 • 160 citations

Control of Phenotypic Expresssion of Cultured Melanoma Cells by Melanocyte Stimulating Hormones

1973 • 160 citations

Newcastle disease virus-infected splenocytes express the proopiomelanocortin gene.

1986 • 160 citations

Proopiomelanocortin, corticotropin releasing hormone and corticotropin releasing hormone receptor genes are expressed in human skin

1995 • 159 citations

Hormonal Regulation of Human Corticotropin-Releasing Hormone Gene Expression: Implications for the Stress Response and Immune/Inflammatory Reaction

1994 • 158 citations

Autoradiographic Localization of CRF1 and CRF2 Binding Sites in Adult Rat Brain

1997 • 158 citations

Melanocyte-stimulating hormone promotes activation of pre-existing tyrosinase molecules in Cloudman S91 melanoma cells

1975 • 157 citations

Melanocytes as "Sensory" and Regulatory Cells in the Epidermis

1993 • 156 citations

Evidence for the differential expression of the functional alpha-melanocyte-stimulating hormone receptor MC-1 on human monocytes.

1997 • 156 citations

Proopiomelanocortin-Derived Peptides

1994 • 155 citations

alpha-Melanocyte-stimulating hormone induces hapten-specific tolerance in mice.

1996 • 153 citations

Obesity, Diabetes and Functions for Proopiomelanocortin-derived Peptides

1997 • 152 citations

Relief of Intractable Pruritus With Naloxone

1979 • 152 citations

β-endorphin in the immune system: a role at last?

1997 • 151 citations

Corticotropin releasing hormone in colonic mucosa in patients with ulcerative colitis.

1995 • 150 citations

Differential Expression and Activity of Melanogenesis-Related Proteins During Induced Hair Growth in Mice

1991 • 149 citations

Corticotropin positively regulates its own receptors and cAMP response in cultured bovine adrenal cells.

1989 • 147 citations

Cutaneous Expression of CRH and CRH‐R: Is There a “Skin Stress Response System?”

1999 • 145 citations

Corticotropin-releasing hormone-induced vasodilatation in the human fetal-placental circulation: involvement of the nitric oxide-cyclic guanosine 3',5'-monophosphate-mediated pathway.

1995 • 145 citations

Proopiomelanocortin Gene Product Regulation in Keratinocytes

1996 • 145 citations

Structure and function of adhesion receptors in leukocyte trafficking

1995 • 145 citations

Animals under the sun: effects of ultraviolet radiation on mammalian skin

1998 • 143 citations

After Dopachrome?

1991 • 143 citations

Mast Cell Involvement in Murine Hair Growth

1994 • 142 citations

Activation of the cyclic AMP pathway by alpha-melanotropin mediates the response of human melanocytes to ultraviolet B radiation.

1998 • 141 citations

Alpha-melanocyte-stimulating hormone reduces endotoxin-induced liver inflammation.

1996 • 140 citations

Expression and protective effects of urocortin in cardiac myocytes

1998 • 139 citations

Specific Receptors for α-Melanocyte-Stimulating Hormone Are Widely Distributed in Tissues of Rodents

1987 • 138 citations

A Murine Model for Inducing and Manipulating Hair Follicle Regression (Catagen): Effects of Dexamethasone and Cyclosporin A

1994 • 137 citations

Human placenta and fetal membranes express human urocortin mRNA and peptide.

1996 • 136 citations

Corticotrophin-releasing factor-like immunoreactivity and mRNA in human leukocytes

1990 • 136 citations

On the potential role of proopiomelanocortin in skin physiology and pathology

1993 • 135 citations

Cytokines

1998 • 135 citations

Expression of corticotropin-releasing factor in inflamed tissue is required for intrinsic peripheral opioid analgesia.

1996 • 134 citations

Human dermal microvascular endothelial cells express the melanocortin receptor type 1 and produce increased levels of IL-8 upon stimulation with alpha-melanocyte-stimulating hormone.

1997 • 134 citations

Proopiomelanocortin Gene is Expressed in Many Normal Human Tissues and in Tumors not Associated with Ectopic Adrenocorticotropin Syndrome

1988 • 133 citations

Corticotropin-releasing factor (CRF) and glucocorticoids modulate the expression of type 1 CRF receptor messenger ribonucleic acid in rat anterior pituitary cell cultures.

1996 • 132 citations

Binding of α-melanocyte-stimulating hormone to its G-protein-coupled receptor on B-lymphocytes activates the Jak/STAT pathway

1998 • 132 citations

Hormonal Regulation Of POMC Gene Expression

1989 • 130 citations

Proopiomelanocortin, Its Derived Peptides, and the Skin

1996 • 128 citations

Adenosine 3′,5′-Monophosphate (Cyclic AMP) as the Mediator of the Actions of Melanocyte Stimulating Hormone (MSH) and Norepinephrine on the Frog Skin¹

1969 • 127 citations

Human Lymphocytes Produce Urocortin, But Not Corticotropin-Releasing Hormone

1998 • 125 citations

Corticotropin‐releasing factor: an antireproductive hormone of the testis

1993 • 125 citations

Bacterial lipopolysaccharide induction of leukocyte-derived corticotropin and endorphins

1985 • 123 citations

Expression of pro-opiomelanocortin gene and quantification of adrenocorticotropic hormone-like immunoreactivity in human normal peripheral mononuclear cells and lymphoid and myeloid malignancies.

1989 • 123 citations

Regulation of Melanocyte Stimulating Hormone Action at the Receptor Level: Discontinuous Binding of Hormone to Synchronized Mouse Melanoma Cells During the Cell Cycle

1974 • 120 citations

Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth.

1993 • 120 citations

Ultraviolet B and Melanocyte-Stimulating Hormone (MSH) Stimulate mRNA Production for ∝MSH Receptors and Proopiomelanocortin-Derived Peptides in Mouse Melanoma Cells and Transformed Keratinocytes

1995 • 118 citations

Proopiomelanocortin expression in the skin during induced hair growth in mice

1992 • 118 citations

Evidence for alpha‐melanocyte‐stimulating hormone (α‐MSH) receptors on human malignant melanoma cells

1988 • 117 citations

POTENTIAL MECHANISM OF SKIN RESPONSE TO STRESS

1996 • 117 citations

Expression of Melanocortin-5 Receptor in Secretory Epithelia Supports a Functional Role in Exocrine and Endocrine Glands¹

1998 • 117 citations

A new functional isoform of the human CRF2 receptor for corticotropin-releasing factor

1997 • 116 citations

Expression of the mouse corticotropin-releasing hormone gene in vivo and targeted inactivation in embryonic stem cells.

1994 • 115 citations

Murine Leukemia Inhibitory Factor Gene Disruption Attenuates the Hypothalamo-Pituitary-Adrenal Axis Stress Response¹

1998 • 113 citations

Expression of μ-Opiate Receptor in Human Epidermis and Keratinocytes

1998 • 111 citations

The effect of melanocyte-stimulating hormone on coat color in the mouse.

1972 • 111 citations

Stress, Neuropeptides, and Systemic Disease

1991 • 111 citations

Cutaneous Immunomodulation and Coordination of Skin Stress Responses by α‐Melanocyte‐Stimulating Hormone^a

1998 • 110 citations

Corticotropin-releasing factor-binding protein is produced by human placenta and intrauterine tissues.

1993 • 109 citations

Human decidua and in vitro decidualized endometrial stromal cells at term contain immunoreactive corticotropin-releasing factor (CRF) and CRF messenger ribonucleic acid.

1992 • 109 citations

Molecular Cascades in UV Induced Melanogenesis: A Central Role for Melanotropins?

1992 • 108 citations

Melanotropin and Corticotropin Are Encoded on Two Distinct Genes in the Lamprey, the Earliest Evolved Extant Vertebrate

1995 • 108 citations

Neural Mechanisms of Hair Growth Control

1997 • 108 citations

Corticotropin-releasing factor in antinociception and inflammation

1997 • 108 citations

Activated skin mast cells are involved in murine hair follicle regression (catagen).

1997 • 103 citations

Nonsteroidal signals originating in the gonads

1992 • 103 citations

Response of mouse melanoma cells to melanocyte stimulating hormone

1974 • 103 citations

The mouse genome contains two nonallelic pro-opiomelanocortin genes.

1983 • 100 citations

Isolation and Characterization of the Bovine Corticotropin/β-Lipotropin Precursor Gene

2005 • 100 citations

Characterization of Corticotropin-Releasing Hormone (CRH) in Human Skin¹

1998 • 99 citations

Melanocortin Receptor Genes in the Chicken—Tissue Distributions

1998 • 98 citations

Systematic Mutation Screening of the Pro-Opiomelanocortin Gene: Identification of Several Genetic Variants Including Three Different Insertions, One Nonsense and Two Missense Point Mutations in Probands of Different Weight Extremes

1998 • 98 citations

CRF Type I Receptor-Deficient Mice Exhibit a Pronounced Pituitary-Adrenal Response to Local Inflammation

1999 • 94 citations

The expression of proopiomelanocortin (POMC) and of corticotropin releasing hormone receptor (CRH-R) genes in mouse skin

1996 • 93 citations

The Structures of the Mouse and Human Urocortin Genes (Ucn and UCN)

1998 • 93 citations

Secretion of Peptides and Proteins Lacking Hydrophobic Signal Sequences: The Role of Adenosine Triphosphate-Driven Membrane Translocators*

1992 • 92 citations

Cytokine Regulation of the Rat Proopiomelanocortin Gene Expression in AtT-20 Cells

1998 • 92 citations

Corticotropin-releasing hormone modulates cytokines release in cultured human peripheral blood mononuclear cells

1993 • 91 citations

Hair cycle-dependent expression of corticotropin-releasing factor (CRF) and CRF receptors in murine skin

1998 • 90 citations

UV Light and MSH Receptors

1999 • 89 citations

Unusual Proopiomelanocortin Ribonucleic Acids in Extrapituitary Tissues: Intronless Transcripts in Testes and Long Poly(A) Tails in Hypothalamus

1987 • 89 citations

Pituitary Corticotroph SOCS-3: Novel Intracellular Regulation of Leukemia-Inhibitory Factor-Mediated Proopiomelanocortin Gene Expression and Adrenocorticotropin Secretion

1998 • 89 citations

Corticotropin-releasing hormone stimulates Ca2+ entry through L- and P-type Ca2+ channels in rat corticotropes.

1996 • 87 citations

The human melanocyte stimulating hormone receptor has evolved to become “super-sensitive” to melanocortin peptides

1994 • 86 citations

Antiinflammatory Effects of the Neuropeptide α‐MSH in Acute, Chronic, and Systemic Inflammationa

1994 • 85 citations

Pro-opiomelanocortin gene expression and protein processing in rat mononuclear leukocytes

1997 • 85 citations

Immunosuppressive effects of corticotropin and melanotropin and their possible significance in human immunodeficiency virus infection.

1992 • 83 citations

Expression of Corticotropin-Releasing Hormone and Its R1 receptor in Human Endometrial Stromal Cells

1997 • 83 citations

Regional Distribution of Urocortin-like Immunoreactivity and Expression of Urocortin mRNA in the Human Brain

1998 • 83 citations

The corticotrophin-releasing factor-binding protein: an act of several parts

1998 • 82 citations

Association of cell surface receptors for melanotropin with the Golgi region in mouse melanoma cells.

1976 • 82 citations

Action of the e Locus of Mice in the Response of Phaeomelanic Hair Follicles to α-Melanocyte-Stimulating Hormone in Vitro

1984 • 82 citations

Alpha-Melanocyte Stimulating Hormone Modulates Contact Hypersensitivity Responsiveness in C57/BL6 Mice

1989 • 82 citations

Characterization of the relaxant action of urocortin, a new peptide related to corticotropin‐releasing factor in the rat isolated basilar artery

1998 • 81 citations

Skin immune system (SIS)

2000 • 81 citations

Interleukin 1 beta mediates stress-induced immunosuppression via corticotropin-releasing factor.

1992 • 81 citations

Urocortin, a corticotropin-releasing factor-related mammalian peptide, inhibits edema due to thermal injury in rats

1996 • 81 citations

Distribution and concentration of urocortin, and effect of adrenalectomy on its content in rat hypothalamus

1998 • 80 citations

Mechanisms of Antiinflammatory Action of the Neuroimmunomodulatory Peptide α‐MSH

1998 • 79 citations

Peripheral beta-endorphin and pain modulation.

1991 • 79 citations

The natural history of a family of transplantable melanomas in hamsters

1988 • 78 citations

Retinoic Acid is a Potent Inhibitor of Inducible Pigmentation in Murine and Hamster Melanoma Cell Lines

1990 • 78 citations

Human lymphocytes produce pro-opiomelanocortin gene-related transcripts. Effects of lymphotropic viruses.

1988 • 78 citations

Ultraviolet B stimulates production of corticotropin releasing factor (CRF) by human melanocytes

1996 • 78 citations

Mechanism of action of interleukin-1β in increasing corticotropin-releasing factor and adrenocorticotropin hormone release from cultured human placental cells

1990 • 77 citations

Modulation of melanocyte-stimulating hormone receptor expression on normal human melanocytes: evidence for a regulatory role of ultraviolet B, interleukin-1α, interleukin-1β, endothelin-1 and tumour necrosis factor-α

1998 • 77 citations

On the Nature of the Pigmentation Changes Following Hypophysectomy in the Frog Larva

1919 • 76 citations

The Skin Produces Urocortin¹

2000 • 76 citations

Activation of melanoma tyrosinase by a cyclic AMP-dependent protein kinase in a cell-free system

1977 • 76 citations

Cloning and expression of two proopiomelanocortin mRNAs in the common carp (Cyprinus carpio L.)

1998 • 76 citations

Urocortin, a Newly Identified Corticotropin-Releasing Factor-Related Mammalian Peptide, Stimulates Atrial Natriuretic Peptide and Brain Natriuretic Peptide Secretions from Neonatal Rat Cardiomyocytes

1998 • 74 citations

Regulation of Melanogenesis in Melanocytes

1988 • 73 citations

Induction of β-Endorphin Secretion by Lymphocytes after Subcutaneous Administration of Corticotropin-Releasing Factor

1990 • 72 citations

Human Peripheral Blood‐Derived Dendritic Cells Express Functional Melanocortin Receptor MC‐1R

1999 • 71 citations

Mechanisms of the Antiinflammatory Effects of α‐MSH: Role of Transcription Factor NF‐κB and Adhesion Molecule Expression

1999 • 71 citations

The Skin POMC System (SPS): Leads and Lessons from the Hair Follicle

1999 • 70 citations

Opioid peptides modulate immune functions. A review

1988 • 70 citations

α-MSH peptides inhibit acute inflammation induced in mice by rIL-1β, rIL-6, rTNF-α and endogenous pyrogen but not that caused by LTB4, PAF and rIL-8

1992 • 70 citations

The melanocortin 1, 3, 4 or 5 receptors do not have a binding epitope for ACTH beyond the sequence of alpha-MSH

1997 • 70 citations

The Human Placenta and Fetal Membranes Express the Corticotropin-Releasing Hormone Receptor 1α (CRH-1α) and the CRH-C Variant Receptor¹

1998 • 69 citations

Alpha‐Melanocyte‐Stimulating Hormone Modulates Activation of NF‐κB and AP‐1 and Secretion of Interleukin‐8 in Human Dermal Fibroblasts

1999 • 69 citations

In Vitroandin VivoAnalysis of the Processing and Fate of the Peptide Products of the Short Proopiomelanocortin mRNA

1990 • 69 citations

Regulation of the Rat Proopiomelanocortin Gene Expression in AtT-20 Cells. I: Effects of the Common Secretagogues

1997 • 68 citations

Vasodilator Actions of Urocortin and Related Peptides in the Human Perfused Placenta in Vitro1

1998 • 67 citations

Production of POMC, CRH-R1, MC1, and MC2 Receptor mRNA and Expression of Tyrosinase Gene in Relation to Hair Cycle and Dexamethasone Treatment in the C57BL/6 Mouse Skin

1997 • 66 citations

Human Corticotropin-Releasing Hormone Receptor: Differences in Subtype Expression between Pregnant and Nonpregnant Myometria¹

1998 • 66 citations

The three-way interactions between the hypothalamic-pituitary-adrenal and gonadal axes and the immune system

1996 • 66 citations

Melanoma cells resistant to inhibition of growth by melanocyte stimulating hormone.

1975 • 65 citations

Relationship between antigen-induced immune stimulation and activation of the hypothalamic-pituitary-adrenal axis in the rat.

1993 • 65 citations

Corticotropin-Releasing Hormone Receptor Subtype 1 Is Significantly Up-Regulated at the Time of Labor in the Human Myometrium1

1998 • 64 citations

Novel processing pathway for proopiomelanocortin in lymphocytes: Endotoxin induction of a new prohormone‐Cleaving enzyme

1987 • 64 citations

Effects of corticotropin-releasing hormone on ovarian estrogen production in vitro.

1996 • 64 citations

Cellular and Extracellular Regulatory Mechanisms of Hypothalamic Corticotropin-Releasing Hormone Neurons.

1998 • 63 citations

Melanoma cells which require cyclic AMP for growth

1975 • 62 citations

Absence of Dopaminergic Control on Melanotrophs Leads to Cushing’s-Like Syndrome in Mice

1998 • 62 citations

Interferons modulate the expression of hormone receptors on the surface of murine melanoma cells.

1989 • 62 citations

Expression of Proopiomelanocortin, Corticotropin-Releasing Hormone (CRH), and CRH Receptor in Melanoma Cells, Nevus Cells, and Normal Human Melanocytes

1999 • 61 citations

Expression of proopiomelanocortin (POMC)-derived melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH) peptides in skin of basal cell carcinoma patients

1999 • 61 citations

Glucocorticoid Regulation of Hypothalamic Proopiomelanocortin

1998 • 61 citations

Involvement of nitric oxide in basal and interleukin-1β-induced CRH and ACTH release in vitro

1993 • 61 citations

The Opioid Growth Factor, [Met5]-Enkephalin, and the ζ(Zeta) Opioid Receptor Are Present in Human and Mouse Skin and Tonically Act to Inhibit DNA Synthesis in the Epidermis

1996 • 60 citations

MSH receptors in immortalized human epidermal keratinocytes: A potential mechanism for coordinate regulation of the epidermal‐melanin unit

1993 • 60 citations

Alpha-MSH peptides inhibit acute inflammation and contact sensitivity

1990 • 59 citations

Enhanced Expression of Melanocortin-1 Receptor (MC1-R) in Normal Human Keratinocytes During Differentiation: Evidence for Increased Expression of POMC Peptides Near Suprabasal Layer of Epidermis

1999 • 59 citations

Structural/functional relationships between internal and external MSH receptors: Modulation of expression in Cloudman melanoma cells by UVB radiation

1991 • 59 citations

Production of Immunosuppressing Melanotropins By Human Keratinocytes^a

1993 • 59 citations

Central Actions of Corticotropin‐Releasing Factor on Autonomic Nervous Activity and Cardiovascular Functioning

2007 • 58 citations

The Genomic Structure of the Rat Corticotropin Releasing Factor Receptor

1996 • 58 citations

Immunoreactivity of alpha-melanocyte-stimulating hormone, adrenocorticotrophic hormone and beta-endorphin in cutaneous malignant melanoma and benign melanocytic naevi

1998 • 58 citations

Role of tyrosine kinase and protein kinase C in the steroidogenic actions of angiotensin II, α-melanocyte-stimulating hormone and corticotropin in the rat adrenal cortex

1995 • 58 citations

Leukemia Inhibitory Factor Modulates Interleukin-1β-Induced Activation of the Hypothalamo-Pituitary-Adrenal Axis¹

1998 • 57 citations

CORTICOTROPIN RELEASING HORMONE AND RELATED PEPTIDES CAN ACT AS BIOREGULATORY FACTORS IN HUMAN KERATINOCYTES

2000 • 57 citations

Corticotropin-releasing hormone differentially modulates the interleukin-1 system according to the level of monocyte activation by endotoxin.

1995 • 57 citations

Pharmacological Disruption of Hair Follicle Pigmentation by Cyclophosphamide as a Model for Studying the Melanocyte Response to and Recovery from Cytotoxic Drug Damage In Situ

1996 • 57 citations

Alpha-Melanocyte-Stimulating Hormone Immunoreactivity in Melanoma Cells

1990 • 56 citations

α-Melanocyte Stimulating Hormone-Induced Pigmentation Is Blocked by Depletion of Protein Kinase C

1996 • 56 citations

Effect of PUVA on plasma and skin immunoreactive α-melanocyte stimulating hormone concentrations

1987 • 56 citations

Local production of corticotropin releasing hormone is increased in experimental intestinal inflammation in rats.

1996 • 55 citations

α-MSH regulates interleukin-10 expression by human keratinocytes

1998 • 55 citations

α-melanocyte-stimulating hormone reduces interleukin-lβ effects on rat stomach preparations possibly through interference with a type I receptor

1991 • 55 citations

Effect of CRF and related peptides on calcium signaling in human and rodent melanoma cells

1998 • 54 citations

Melanocyte stimulating hormone induces the differentiation of mouse epidermal melanocytes in serum‐free culture

1992 • 54 citations

POMC gene expression in mouse and hamster melanoma cells

1991 • 54 citations

Corticotropin-Releasing Hormone and Proopiomelanocortin-Derived Peptides Are Present in Human Myometrium

1998 • 54 citations

The Pilosebaceous Unit Is Part of the Skin Immune System

1998 • 53 citations

Cloning and Characterization of a Short Variant of the Corticotropin-Releasing Factor Receptor Subtype from Rat Amygdala

1999 • 53 citations

In VivoImmunoreactive Adrenocorticotropin (ACTH) Production by Human Mononuclear Leukocytes from Normal and ACTH-Deficient Individuals*

1987 • 52 citations

Molecular Basis of the α‐MSH/IL‐1 Antagonism

1999 • 52 citations

Detection of melanocortin‐1 receptor antigenicity on human skin cells in culture and in situ

1999 • 52 citations

Expression of Genes Encoding Corticotropin-Releasing Factor (CRF), Type 1 CRF Receptor, and CRF-Binding Protein and Localization of the Gene Products in the Human Ovary1

1997 • 52 citations

Proopiomelanocortin gene expression in a distinct population of rat spleen and lung leukocytes.

1992 • 52 citations

Neuronal histamine and expression of corticotropin-releasing hormone, vasopressin and oxytocin in the hypothalamus: relative importance of H1 and H2 receptors

1998 • 51 citations

The Anticytokine Neuropeptide α-Melanocyte-Stimulating Hormone in Synovial Fluid of Patients with Rheumatic Diseases: Comparisons with Other Anticytokine Molecules

1994 • 51 citations

Immunosuppressive activity of corticotrophin-releasing factor. Inhibition of interleukin-1 and interleukin-6 production by human mononuclear cells

1992 • 51 citations

Tissue-specific activity of the pro-opiomelanocortin (POMC) gene and repression by glucocorticoids

1989 • 51 citations

Comparison of hCRF and oCRF effects on cardiovascular responses after central, peripheral, and in vitro application

1995 • 50 citations

UVB-Induced melanogenesis may be mediated through the MSH-receptor system

1989 • 50 citations

Nucleotide sequence and expression of the mouse corticotropin-releasing hormone gene

1991 • 50 citations

Studies on the Cloudman melanoma cell line as a model for the action of MSH.

1985 • 50 citations

Hair cycle-dependent production of ACTH in mouse skin

1998 • 49 citations

Modulation of ICAM-1 expression by α-MSH in human melanoma cells and melanocytes

1998 • 49 citations

Evidence suggesting that a cyclic AMP‐dependent protein kinase is a positive regulator of proliferation in Cloudman S91 melanoma cells

1979 • 48 citations

Proliferation of the murine corticotropic tumour cell line AtT20 is affected by hypophysiotrophic hormones, growth factors and glucocorticoids

1995 • 48 citations

The Discovery of the Melanotropins: A History of Pituitary Endocrinology^a

1993 • 48 citations

Molecular Properties of the CRF Receptor

1998 • 48 citations

Role of Epidermal Cell-Derived α-Melanocyte Stimulating Hormone in Ultraviolet Light Mediated Local Immunosuppression

1999 • 48 citations

MSH inhibits growth in a line of amelanotic hamster melanoma cells and induces increases in cyclic AMP levels and tyrosinase activity without inducing melanogenesis

1989 • 47 citations

Post-translational modification of bovine pro-opiomelanocortin. Tyrosine sulfation and pyroglutamate formation, a mass spectrometric study.

1990 • 47 citations

Effect of acetylcholine on corticotropin-releasing factor gene expression in the hypothalamic paraventricular nucleus of conscious rats.

1995 • 46 citations

Regulation of corticotropin-releasing factor secretion from Leydig cells by serotonin.

1992 • 46 citations

α-Melanocyte-stimulating hormone stimulates protein kinase C activity in murine B16 melanoma

1992 • 46 citations

Corticotropin-releasing hormone receptor expression and functional coupling in neonatal cardiac myocytes and AT-1 cells.

1996 • 45 citations

L-Tyrosine stimulates induction of tyrosinase activity by MSH and reduces cooperative interactions between MSH receptors in hamster melanoma cells

1989 • 45 citations

The bigger the burn, the greater the stress

1997 • 45 citations

The genomic organization of the human corticotropin-releasing factor type-1 receptor

1998 • 45 citations

Stimulation of Follicular Melanogenesis in the Mouse by Topical and Injected Melanotropins

1987 • 45 citations

Plasma α-melanocyte-stimulating hormone, β-endorphin, met-enkephalin, and natural killer cell activity in vitiligo

1992 • 44 citations

Cytokines as mediators in the regulation of the hypothalamic-pituitary-adrenocortical function

1994 • 44 citations

Calcium Ion as a Second Messenger for o-Nitrophenylsulfenyl-Adrenocorticotropin (NPS-ACTH) and ACTH in Bovine Adrenal Steroidogenesis**This work was supported, in part, by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan (09680623, Priority Area 09235223).

1998 • 43 citations

α-Melanocyte Stimulating Hormone Induces Collagenase/Matrix Metalloproteinase-1 in Human Dermal Fibroblasts

1995 • 42 citations

What controls melanogenesis?

1998 • 42 citations

Increased concentration of beta-endorphin in the sera of patients with severe atopic dermatitis.

1995 • 41 citations

Human beta-melanocyte-stimulating hormone revisited.

1986 • 41 citations

Localization of Corticotropin-Releasing Factor in Primary and Secondary Lymphoid Organs of the Rat

1998 • 41 citations

Expression of corticotrophin-releasing hormone receptor mRNA and protein in the human myometrium

1998 • 41 citations

Dynorphin peptides: antagonists of melanocortin receptors.

1997 • 41 citations

Alpha-melanocyte-stimulating hormone antagonizes the neuroendocrine effects of corticotropin-releasing factor and interleukin-1 alpha in the primate.

1992 • 40 citations

Corticotropin-releasing hormone, proopiomelanocortin, and glucocorticoid receptor gene expression in adrenocorticotropin-producing tumors in vitro.

1993 • 40 citations

The cDNA structure of the porcine pro‐hormone convertase PC2 and the comparative processing by PC1 and PC2 of the N‐terminal glycopeptide segment of porcine POMC

1992 • 39 citations

The Expression of Proopiomelanocortin and Various POMC‐Derived Peptides in Mouse and Human Skin

1993 • 39 citations

Involvement of serotonergic pathways in mediating the neuronal activity and genetic transcription of neuroendocrine corticotropin-releasing factor in the brain of systemically endotoxin-challenged rats

1999 • 39 citations

Regulation of the Rat Proopiomelanocortin Gene Expression in AtT-20 cells. II: Effects of the Pituitary Adenylate Cyclase-Activating Polypeptide and Vasoactive Intestinal Polypeptide

1997 • 39 citations

Corticotropin-releasing hormone (CRH) receptors in the mesenteric small arteries of rats resemble the (2)-subtype

1996 • 39 citations

Pro-opiomelanocortin mRNA size heterogeneity in ACTH-dependent Cushing's syndrome

1989 • 38 citations

Propiomelanocortin (POMC) gene expression by normal skin and keloid fibroblasts in culture: modulation by cytokines

1997 • 38 citations

Receptors for .beta.-melanocyte-stimulating hormone exhibit positive cooperativity in synchronized melanoma cells

1988 • 38 citations

Role of leukocyte-derived pro-opiomelanocortin peptides in endotoxic shock.

1991 • 37 citations

Expression of Functional Melanocortin Receptors and Proopiomelanocortin Peptides by Human Dermal Microvascular Endothelial Cells

1999 • 37 citations

Secretion of Immunoreactive Corticotropin Releasing Factor and Adrenocorticotropic Hormone by T- and B-Lymphocytes in Response to Cellular Stress Factors

1994 • 37 citations

Steroid hormones regulate the release of immunoreactive beta-endorphin from the Ishikawa human endometrial cell line.

1992 • 36 citations

Phosphorylated isomers of L-dopa stimulate MSH binding capacity and responsiveness to MSH in cultured melanoma cells

1987 • 36 citations

Selective properties of C- and N-terminals and core residues of the melanocyte-stimulating hormone on binding to the human melanocortin receptor subtypes

1998 • 36 citations

NEUROPEPTIDES IN PSORIASIS: POSSIBLE ROLE OF BETA‐ENDORPHIN IN THE PATHOMECHANISM OF THE DISEASE

1994 • 35 citations

Interactions between ultraviolet light and interleukin-1 on MSH binding in both mouse melanoma and human squamous carcinoma cells

1991 • 35 citations

Internal binding sites for MSH: Analyses in wild‐type and variant Cloudman melanoma cells

1990 • 35 citations

The kinetics of ACTH expression in rat leukocyte subpopulations

1995 • 35 citations

A molecular mechanism for stress-induced alterations in susceptibility to disease

1995 • 34 citations

Corticotropin-releasing hormone is produced by rat corticotropes and modulates ACTH secretion in a paracrine/autocrine fashion.

1998 • 34 citations

Peptide biosynthetic processing: distinguishing prohormone convertases PC1 and PC2

1996 • 34 citations

Melanocyte-Stimulating Hormone: A Regulator of Human Melanocyte Physiology

1995 • 34 citations

α‐melanocyte stimulating hormone inhibits tumour necrosis factor‐α stimulated intercellular adhesion molecule‐1 expression in normal cutaneous human melanocytes and in melanoma cell lines

1998 • 34 citations

Stable expression of normal and mutant human ACTH receptor

1997 • 34 citations

Anti-neoplastic properties of human corticotropin releasing factor: involvement of the nitric oxide pathway.

1998 • 34 citations

Paracrine regulation of human placenta: control of hormonogenesis

1998 • 34 citations

Genetic Control of Melanization: Isolation and Analysis of Amelanotic Variants from Cultured Melanotic Melanoma Cells

1974 • 33 citations

Melanocyte-stimulating hormone and the regulation of tyrosinase activity in hair follicular melanocytes of the mouse

1986 • 33 citations

Immunoreactive α‐Melanotropin as an Autocrine Effector in Human Melanoma Cells

1997 • 33 citations

Melanocortins and their implication in melanoma

1995 • 33 citations

α-Melanocyte Stimulating Hormone Downregulates Differentiation-Driven Heat Shock Protein 70 Expression in Keratinocytes

1997 • 33 citations

The Distribution of Forms of Adrenocorticotropin and Endorphin in Normal, Tumorous, and Autopsy Human Anterior Pituitary Tissue: Virtual Absence of 13K Adrenocorticotropin*

1980 • 33 citations

Raised β-endorphin serum levels in children with atopic dermatitis and pruritus

1994 • 33 citations

Corticotrophin-releasing hormone-binding protein in human fetal plasma

1995 • 33 citations

[Modification of alpha-MSH by UVA irradiation of the skin].

1983 • 33 citations

Expression of melanocyte stimulating hormone receptors correlates with mammalian pigmentation, and can be modulated by interferons

1988 • 32 citations

Corticotropin-Releasing Factor (CRF) Agonists Stimulate Testosterone Production in Mouse Leydig Cells through CRF Receptor-1*

1998 • 32 citations

Effects of β-MSH, Cortisol and ACTH on Tyrosinase in the Skin of Newborn Hamsters and Mice

1970 • 32 citations

Characteristics and kinetics of proopiomelanocortin mRNA expression by human leucocytes

1991 • 31 citations

Protein kinase-C activation increases the quantity and poly(A) tail length of corticotropin-releasing hormone messenger RNA in NPLC cells.

1992 • 31 citations

Hormonal Control of Pelage Cycles In The Mink

1965 • 31 citations

Peripheral Anti-Inflammatory Actions of Corticotropin-Releasing Factor

2007 • 30 citations

Nitric oxide regulation of corticotropin-releasing hormone release from the human perfused placenta in vitro.

1996 • 30 citations

Stimulation of tyrosinase in human melanocytes by pro-opiomelanocortin-derived peptides

1995 • 30 citations

Studies on the intracellular mechanism of action of -melanocyte-stimulating hormone on rat adrenal zona glomerulosa

1992 • 30 citations

Regulation of tyrosinase synthesis by α-melanocyte-stimulating hormone in hair follicular melanocytes of the mouse

1988 • 30 citations

Stimulation of cAMP and phosphomonoester production by melanotropin in melanoma cells: 31P NMR studies.

1991 • 29 citations

A case of skin hyperpigmentation due to α-MSH hypersecretion

1992 • 29 citations

Modulation of skin cell functions by transforming growth factor-beta1 and ACTH after ultraviolet irradiation

1998 • 28 citations

d-amino acid-substituted analogs of corticotropin-releasing hormone (CRH) and urocortin with selective agonist activity at CRH1 and CRH2β receptors

1998 • 28 citations

Evidence for γ-Melanocyte Stimulating Hormone Containing Nerves and Neutrophilic Granulocytes in the Human Skin by Indirect Immunofluorescence

1990 • 28 citations

Stimulation of Adenosine 3′,5′-Monophosphate Production in Rat Sertoli Cells byα-Melanotropin- Stimulating Hormone (αMSH) and Des-AcetylαMSH*

1986 • 28 citations

Localization of Immunoreactive β-Endorphin and Adrenocorticotropic Hormone and Pro-Opiomelanocortin mRNA to Rat Testicular Interstitial Tissue Macrophages

1991 • 28 citations

Identification and measurement of β-endorphin levels in the skin during induced hair growth in mice

1997 • 27 citations

Ultraviolet B-Exposed and Soluble Factor-Pre-Incubated Epidermal Langerhans Cells Fail to Induce Contact Hypersensitivity and Promote DNP-Specific Tolerance

1997 • 27 citations

Characterization of a Human-Specific Regulator of Placental Corticotropin-Releasing Hormone

1998 • 26 citations

Stimulation of the receptor for melanocyte‐stimulating hormone by retinoic acid

1990 • 26 citations

UVA EXPOSURE AND PITUITARY SECRETION. VARIATIONS OF HUMAN LIPOTROPIN CONCENTRATIONS (βLPH) AFTER UVA EXPOSURE

1985 • 26 citations

Corticotropin-releasing factor-like peptides increase cytosolic [Ca2+] in human epidermoid A-431 cells

1997 • 26 citations

Degradation of alpha‐melanocyte stimulating hormone (alpha‐MSH) by CALLA/endopeptidase 24. 11 expressed by human melanoma cells in culture

1990 • 26 citations

Up-regulation of MSH receptors by MSH in cloudman melanoma cells

1992 • 25 citations

Melanocortin receptors and antagonists regulate pigmentation and body weight

1998 • 25 citations

N-Acetyl-β-endorphin1–31 antagonizes the suppressive effect of β-endorphin1–31 on murine splenocyte proliferation via A naloxone-resistant receptor

1991 • 25 citations

Effect of corticotropin-releasing factor on prostaglandin synthesis in endothelial cells and fibroblasts.

1995 • 25 citations

Hairless Pigmented Guinea Pigs: A New Model for the Study of Mammalian Pigmentation

1990 • 25 citations

Corticotropin-releasing factor increases [Ca2+]i via receptor-mediated Ca2+ channels in human epidermoid A-431 cells

1994 • 25 citations

Distribution of Lys-γ2-melanocyte-stimulating hormone-(Lys-γ2-MSH)-like immunoreactivity in neuronal elements in the brain and peripheral tissues of the rat

1996 • 25 citations

Plasma Concentration of Cytokine Antagonists in Patients with HIV Infection

1994 • 25 citations

Carboxyl-terminal tripeptide of α-melanocyte-stimulating hormone antagonizes interleukin-1-induced anorexia

1992 • 25 citations

Melanotropic activity of gamma MSH peptides in melanoma cells

1992 • 25 citations

Human endometrium as a neuroendocrine tissue: Expression, regulation and biological roles of endometrial corticotropin-releasing hormone (CRH) and opioid peptides

1997 • 24 citations

Transcriptional regulation of human corticotropin releasing factor gene expression by cyclic adenosine 3',5'-monophosphate: differential effects at proximal and distal promoter elements

1993 • 24 citations

BOMIRSKI MELANOMAS - A VERSATILE AND POWERFUL MODEL FOR PIGMENT CELL AND MELANOMA RESEARCH (REVIEW)

1993 • 24 citations

Local injections of corticotropin releasing factor reduce doxorubicin-induced acute inflammation in the eyelid.

1997 • 24 citations

Alpha‐Melanocyte‐Stimulating Hormone Immunoreactivity in Human Melanoma Metastases Extracts

1989 • 24 citations

Influence of alpha-melanocyte stimulating hormone on induction of contact hypersensitivity and tolerance

1994 • 23 citations

Corticotropin-Releasing Factor Inhibits Luteinizing Hormone-Stimulated P450c17 Gene Expression and Androgen Production by Isolated Thecal Cells of Human Ovarian Follicles1

1998 • 23 citations

Thy‐1 + dendritic cells express truncated form of POMC mRNA

1995 • 23 citations

The Effect of Ultraviolet B Induced Adult T Cell Leukemia‐Derived Factor/Thioredoxin (ADF/TRX) on Survival and Growth of Human Melanocytes

1997 • 23 citations

Post-translational processing of pro-opiomelanocortin (POMC)-derived peptides during fetal monkey pituitary development

1988 • 23 citations

Studies on factors influencing human plasma alpha-MSH.

1989 • 22 citations

Effect of pituitary autografts on hair color in the short-tailed weasel

1968 • 22 citations

Partial characterization of IR-α-MSH peptides found in melanoma tumors

1992 • 22 citations

C/EBP activates the human corticotropin-releasing hormone gene promoter

1997 • 22 citations

Alpha tocopheryl succinate inhibits melanocyte-stimulating hormone (MSH)-sensitive adenylate cyclase activity in melanoma cells

1987 • 22 citations

Corticotropin releasing factor and its binding protein

1996 • 22 citations

Corticotropin-releasing hormone inhibits lowering of interstitial pressure in rat trachea after neurogenic inflammation

1998 • 21 citations

Identification and Sequencing of a Putative Variant of Proopiomelanocortin in Human Epidermis and Epidermal Cells in Culture

1998 • 21 citations

Effects of Exogenous MSH on the Transformation from Phaeo- to Eumelanogenesis Within C57BL/6J-Ay/a Hairbulb Melanocytes

1991 • 21 citations

MSH binding in bomirski amelanotic hamster melanoma cells is stimulated by L-tyrosine

1987 • 20 citations

The effect of group size on metabolism in huddling grey partridge (Perdix perdix)

1995 • 20 citations

Procorticotrophin-releasing hormone: endoproteolytic processing and differential release of its derived peptides within AtT20 cells

1998 • 20 citations

Effects of Ultraviolet Irradiation on the Cell Cycle

1994 • 19 citations

Homologous Regulation of the MSH Receptor in Melanoma Cells

1993 • 18 citations

Immunohistochemical evidence of α-, β- and γ3-melanocyte stimulating hormone expression in cutaneous malignant melanoma of nodular type

1995 • 17 citations

Differential 5-HT-mediated regulation of stress-induced activation of proopiomelanocortin (POMC) gene expression in the anterior and intermediate lobe of the pituitary in male rats

1997 • 17 citations

Correlation of neuroendocrine and anti-edema activities of alanine-corticotropin-releasing factor analogs

1994 • 17 citations

Alpha-melanocyte-stimulating hormone and N-acetyl-beta-endorphin immunoreactivities are localized in the human pituitary but are not restricted to the zona intermedia.

1994 • 16 citations

The number of receptors for beta-melanocyte stimulating hormone in Cloudman melanoma cells is increased by dibutyryl adenosine 3':5'-cyclic monophosphate or cholera toxin.

1977 • 16 citations

Studies of the role of endothelium‐dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine

1999 • 16 citations

Binding and Biological Activity of C-Terminally Modified Melanocortin Peptides: A Comparison Between Their Actions at Rodent MC1 and MC3 Receptors

1997 • 16 citations

Post-translational processing of human procorticotrophin-releasing factor in transfected mouse neuroblastoma and Chinese hamster ovary cell lines

1997 • 16 citations

The role of the adrenal glands in regulating onset of winter fur growth in mink (Mustela vison)

1992 • 16 citations

Pro‐opiomelanocortin Expression and Potential Function of Pro‐opiomelanocortin Products during Induced Hair Growth in Mice^a

1991 • 14 citations

Modulation of endothelial prostaglandin synthesis by corticotropin releasing factor and antagonists

1998 • 14 citations

Initiation of pro-opiomelanocortin mRNA from a normally quiescent promoter in a human small cell lung cancer cell line

1989 • 14 citations

Corticotropin-releasing factor stimulates cyclic AMP, arachidonic acid release, and growth of lung cancer cells

1994 • 13 citations

Effects of α-melanocyte-stimulating hormone on the cyclic AMP and phospholipid metabolism of rat adrenocortical cells

1986 • 13 citations

EFFECTS OF α-MELANOCYTE-STIMULATING HORMONE AND [8-ARGININE]-VASOTOCIN UPON MELANOGENESIS IN HAIR FOLLICLE MELANOCYTES IN VITRO

1981 • 12 citations

Corticotropin releasing factor modulates interleukin-1-induced prostaglandin synthesis in fibroblasts: receptor binding and effects of antagonists

1998 • 11 citations

Bilateral adrenalectomy induces early onset of summer fur growth in mink (Mustela vison)

1995 • 11 citations

γ‐melanocyte stimulating hormone (γ‐MSH)‐like immunoreactivity is present in certain normal human keratinocytes

1993 • 11 citations

Expression of alpha-melanocyte stimulating hormone and the invasive ability of the B16 murine melanoma.

1992 • 11 citations

Alpha-melanocyte-stimulating hormone reduces endotoxin-induced activation of nuclear factor-κB in endothelial cells

1998 • 10 citations

-Melanocyte-stimulating hormone-induced inhibition of angiotensin II receptor-mediated events in the rat adrenal zona glomerulosa

1994 • 9 citations

Mystixin-7 and mystixin-11 increase cytosolic free Ca2+ and inositol trisphosphates in human A-431 cells

1995 • 8 citations

Proopiomelanocortin‐Derived Peptides and mRNA Are Expressed in Rat Heart

1993 • 8 citations

Immunohistochemical Localization of the Pro-Peptide Processing Enzymes PC1/PC3 and PC2 in the Human Anal Canal

1997 • 8 citations

α-Melanotropin immunoreactivity in human melanoma exudate is related to necrosis

1998 • 7 citations

A Potential for Mutual Regulation of Proopiomelanocortin Gene and Epstein‐Barr Virus Expression in Human Lymphocytes

1990 • 7 citations

Melanocyte-stimulating hormone (alpha-MSH) inhibits the growth of human malignant melanoma cells with the induction of phosphatidyl inositol and myo-inositol phosphate levels.

1991 • 6 citations

Calmodulin-binding peptides interfere with melanocyte-stimulating hormone receptor activity and stimulate adenosine 3',5'-monophosphate production in M2R mouse melanoma cells.

1994 • 6 citations

Expression of Proopiomelanocortin Peptides and Prohormone Convertases by Human Dermal Microvascular Endothelial Cells

1999 • 6 citations

Differential Temporal and Spatial Expression of POMC mRNA and of the Production of POMC Peptides During the Murine Hair Cycle

1999 • 4 citations

Intracellular Retention of the Corticotrophin-releasing Hormone (CRH) Precursor Within COS-7 Cells

1998 • 1 citations

Deleted Work

1955 • 0 citations