Agouti Signaling Protein Inhibits Melanogenesis and the Response of Human Melanocytes to α-Melanotropin

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

1997 • 1,891 citations

The Cloning of a Family of Genes That Encode the Melanocortin Receptors

1992 • 1,616 citations

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

1994 • 1,055 citations

Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans

1995 • 972 citations

Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function

1993 • 873 citations

Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation.

1993 • 428 citations

Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides.

1995 • 373 citations

Binding of melanotropic hormones to the melanocortin receptor MC1R on human melanocytes stimulates proliferation and melanogenesis.

1996 • 313 citations

Obesity, diabetes, and neoplasia in yellow A ^vy /‐ mice: ectopic expression of the agouti gene

1994 • 306 citations

α-melanocyte stimulating hormone and its analogue nle4dphe7α-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes

1994 • 229 citations

Structure and function of ASP, the human homolog of the mouse agouti gene

1995 • 184 citations

Photodestruction of pheomelanin: role of oxygen.

1978 • 180 citations

Molecular structure and chromosomal mapping of the human homolog of the agouti gene.

1994 • 160 citations

Agouti regulation of intracellular calcium: role in the insulin resistance of viable yellow mice.

1995 • 142 citations

The agouti gene: turned on to yellow

1994 • 116 citations

Successful culture of adult human melanocytes obtained from normal and vitiligo donors.

1990 • 114 citations

Nle4DPhe7α-Melanocyte-Stimulating Hormone Increases the Eumelanin:Phaeomelanin Ratio in Cultured Human Melanocytes

1995 • 113 citations

L-Tyrosine-3, 5- ³ H Assay for Tyrosinase Development in Skin of Newborn Hamsters

1969 • 104 citations

α Melanocyte stimulating hormone (αmsh) stimulates normal human melanocyte growth by binding to high-affinity receptors

1993 • 97 citations

Modulation of murine melanocyte function invitro by agouti signal protein

1997 • 96 citations

Action of the e Locus of Mice in the Response of Phaeomelanic Hair Follicles to α-Melanocyte-Stimulating Hormone in Vitro

1984 • 82 citations

Mechanisms for the pleiotropic effects of the agouti gene.

1995 • 75 citations

Agouti Antagonism of Melanocortin Binding and Action in the B16F10 Murine Melanoma Cell Line

1995 • 73 citations

ACTH STIMULATES MELANOGENESIS IN CULTURED HUMAN MELANOCYTES

1994 • 73 citations

Mitogenic, melanogenic, and cAMP responses of cultured neonatal human melanocytes to commonly used mitogens

1992 • 72 citations

Altered patterns of agonist-stimulated cAMP accumulation in cells expressing mutant beta 2-adrenergic receptors lacking phosphorylation sites.

1989 • 70 citations

Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes

1993 • 56 citations

An experimental approach to action of genes at the agouti locus in the mouse. III. Transplants of newborn A^w‐, A‐ and a^t‐ skin to A^y‐, A^w‐, A‐ and aa hosts

1958 • 53 citations

Agouti Protein Inhibits Growth of B16 Melanoma Cellsin Vitroby Acting through Melanocortin Receptors

1996 • 50 citations

AGOUTI PROTEIN CAN ACT INDEPENDENTLY OF MELANOCYTE-STIMULATING HORMONE TO INHIBIT MELANOGENESIS

1995 • 45 citations

The implications of insulin-like growth factor mRNA heterogeneity

1994 • 42 citations

Stimulation of S91 melanoma tyrosinase activity by superpotent α-melanotropins

1985 • 37 citations

Genetic control of signal transduction in mouse melanocytes.

1989 • 31 citations

The neuroendocrine bag cells of Aplysia: a model system for neural control of hormone secretion

1995 • 22 citations

Genetic Control of Signal Transduction in Mouse Melanocytes

1989 • 11 citations