Antiinflammatory Effects of the Neuropeptide α‐MSH in Acute, Chronic, and Systemic Inflammationa

Studies of polyarthritis and other lesions induced in rats by injection of mycobacterial adjuvant. I. General clinical and pathologic characteristics and some modifying factors

1959 • 421 citations

DETECTION OF CYTOKINES AT THE CARTILAGE/PANNUS JUNCTION IN PATIENTS WITH RHEUMATOID ARTHRITIS: IMPLICATIONS FOR THE ROLE OF CYTOKINES IN CARTILAGE DESTRUCTION AND REPAIR

1992 • 233 citations

Neuroimmune networks: physiology and diseases

1990 • 228 citations

Identification of alpha-melanocyte stimulating hormone as a potential immunosuppressive factor in aqueous humor

1992 • 225 citations

Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1.

1986 • 221 citations

α-Melanocyte Stimulating Hormone in the Modulation of Host Reactions*

1993 • 201 citations

Neural control of vascular permeability: interactions between primary afferents, mast cells, and sympathetic efferents

1989 • 193 citations

Histamine: an early messenger in inflammatory and immune reactions

1992 • 187 citations

The Melanotropic Peptides

1988 • 168 citations

Intracerebroventricular infusion of interleukin 1 rapidly decreases peripheral cellular immune responses.

1989 • 150 citations

The Neuropeptide Alpha-Melanocyte-Stimulating Hormone Inhibits Experimental Arthritis in Rats

1994 • 104 citations

The Inflammatory Reaction

1986 • 100 citations

Interleukin-1, Inflammation and Disease

1990 • 98 citations

Antiinflammatory influences of alpha-MSH molecules: central neurogenic and peripheral actions

1994 • 98 citations

The role of platelet-activating factor in inflammation

1990 • 90 citations

CYTOKINE INTER-RELATIONSHIPS AND THEIR ASSOCIATION WITH DISEASE ACTIVITY IN ARTHRITIS

1992 • 86 citations

Human immunodeficiency virus glycoprotein (gp120) infused into rat brain induces interleukin 1 to elevate pituitary-adrenal activity and decrease peripheral cellular immune responses.

1991 • 86 citations

Modulation of IL-1, tumor necrosis factor, and C5a-mediated murine neutrophil migration by alpha-melanocyte-stimulating hormone.

1989 • 84 citations

Central Neurogenic Antiinflammatory Action of α-MSH: Modulation of Peripheral Inflammation Induced by Cytokines and Other Mediators of Inflammation

1994 • 84 citations

Alpha-Melanocyte Stimulating Hormone Modulates Contact Hypersensitivity Responsiveness in C57/BL6 Mice

1989 • 82 citations

Interleukin 1 beta mediates stress-induced immunosuppression via corticotropin-releasing factor.

1992 • 81 citations

Central administration of the peptide α-MSH inhibits inflammation in the skin

1991 • 79 citations

α-MSH peptides inhibit acute inflammation induced in mice by rIL-1β, rIL-6, rTNF-α and endogenous pyrogen but not that caused by LTB4, PAF and rIL-8

1992 • 70 citations

Complement research: biosynthesis, genetics, immunoregulatory role and clinical studies

1992 • 67 citations

Antiinflammatory activity of a COOH-terminal fragment of the neuropeptide alpha-MSH.

1989 • 66 citations

Inhibition of acute inflammation in the periphery by central action of salicylates.

1991 • 60 citations

Modulation of host defense by the neuropeptide alpha-MSH.

1990 • 59 citations

Production of Immunosuppressing Melanotropins By Human Keratinocytes^a

1993 • 59 citations

Alpha-MSH peptides inhibit acute inflammation and contact sensitivity

1990 • 59 citations

The Melanotropic peptides

1993 • 59 citations

Recombinant Human Interleukin-8 Is a Potent Activator of Canine Neutrophil Aggregation, Migration, and Leukotriene B4 Biosynthesis

1991 • 56 citations

Antiinflammatory activity of a COOH‐terminal fragment of the neuropeptide α‐MSH

1989 • 56 citations

Inhibition of IL-1β-induced peripheral inflammation by peripheral and central administration of analogs of the neuropeptide α-MSH

1993 • 55 citations

Neuroimmunology of fever

1993 • 49 citations

Interleukin 1 beta mediates stress-induced immunosuppression via corticotropin-releasing factor

1992 • 45 citations

Anti-inflammatory activity of α-MSH(11–13) analogs: Influences of alteration in stereochemistry

1991 • 40 citations

Double blind controlled phase III multicenter clinical trial with interferon gamma in rheumatoid arthritis

1992 • 32 citations

Interferon-gamma increases human neutrophil-mediated cartilage proteoglycan degradation.

1992 • 11 citations

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