Characterization of a Human-Specific Regulator of Placental Corticotropin-Releasing Hormone

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Current protocols in molecular biology

1988 • 4,543 citations

Textbook of Endocrinology

1952 • 1,475 citations

A placental clock controlling the length of human pregnancy

1995 • 897 citations

Expression of a large family of POU-domain regulatory genes in mammalian brain development

1989 • 828 citations

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

Glucocorticoid stimulates expression of corticotropin-releasing hormone gene in human placenta.

1988 • 437 citations

Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

1987 • 409 citations

A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally.

1989 • 352 citations

A one-hour minipreparation technique for extraction of DNA-binding proteins from animal tissues.

1994 • 341 citations

Modulators of cyclic AMP metabolism induce syncytiotrophoblast formation in vitro

1990 • 317 citations

Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element.

1987 • 293 citations

A sensitive method for the detection of beta-galactosidase in transfected mammalian cells.

1991 • 283 citations

Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.

1995 • 274 citations

Characterization and gestational regulation of corticotropin-releasing hormone messenger RNA in human placenta.

1988 • 267 citations

Cyclic AMP responsiveness of human gonadotropin-alpha gene transcription is directed by a repeated 18-base pair enhancer. Alpha-promoter receptivity to the enhancer confers cell-preferential expression.

1987 • 216 citations

Regulation of jun -B Messenger RNA and AP-1 Activity by Light and a Circadian Clock

1992 • 215 citations

Trophoblast Cell Differentiation: Establishment, Characterization, and Modulation of a Rat Trophoblast Cell Line Expressing Members of the Placental Prolactin Family*

1991 • 204 citations

Identification of a Cyclic Adenosine Monophosphate-Responsive Element in the Rat Corticotropin-Releasing Hormone Gene

1988 • 187 citations

A Single Domain of the Estrogen Receptor Confers Deoxyribonucleic Acid Binding and Transcriptional Activation of the Rat Prolactin Gene

1988 • 173 citations

Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors.

1993 • 164 citations

Both Isoforms of the cAMP-dependent Protein Kinase Catalytic Subunit Can Activate Transcription of the Prolactin Gene

1989 • 162 citations

Expression of the Glycoprotein Hormone a-Subunit Gene in the Placenta Requires a Functional Cyclic AMP Response Element, whereas a Different cis-Acting Element Mediates Pituitary-Specific Expression

1989 • 136 citations

Expression of the mouse corticotropin-releasing hormone gene in vivo and targeted inactivation in embryonic stem cells.

1994 • 115 citations

Identification and characterization of a 3',5'-cyclic adenosine monophosphate-responsive element in the human corticotropin-releasing hormone gene promoter.

1992 • 115 citations

The cAMP signalling system and human trophoblast function

1992 • 111 citations

Species-specific placental corticotropin releasing hormone messenger RNA and peptide expression

1989 • 94 citations

Evolution of Placenta-Specific Gene Expression: Comparison of the Equine and Human Gonadotropin α-Subunit Genes

1991 • 88 citations

Neurotransmitter-synthesizing enzymes in 14 human neuroblastoma cell lines

1981 • 84 citations

Expression of the glycoprotein hormone alpha-subunit gene in the placenta requires a functional cyclic AMP response element, whereas a different cis-acting element mediates pituitary-specific expression.

1989 • 82 citations

Identification and characterization of a 3',5'-cyclic adenosine monophosphate-responsive element in the human corticotropin-releasing hormone gene promoter

1992 • 58 citations

Regulated expression of the human corticotropin releasing hormone gene by cyclic AMP

1990 • 54 citations

Coordinate control of the alpha- and beta-subunit genes of human chorionic gonadotropin by trophoblast-specific element-binding protein.

1993 • 54 citations

Different Combinations of Regulatory Elements May Account For Expression of the Glycoprotein Hormone α-Subunit Gene in Primate and Horse Placenta

1990 • 50 citations

Transcriptional Control of Gene Expression by cAMP‐Response Element Binding Proteins

1994 • 46 citations

A variant insulin promoter in non-insulin-dependent diabetes mellitus.

1992 • 44 citations

Textbook of Endocrinology

2010 • 31 citations

Trans-acting factors dictate the species-specific placental expression of corticotropin-releasing factor genes in choriocarcinoma cell lines.

1996 • 26 citations

Placental corticotrophin-releasing hormone: there by accident or design?

1995 • 18 citations

Molecular and Transgenic Studies of the Corticotropin‐Releasing Hormone Genea

1995 • 13 citations