Dynorphin peptides: antagonists of melanocortin receptors.

Endogenous Opioids: Biology and Function

1984 • 1,223 citations

Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

1982 • 1,160 citations

ACTH-(1–24) and α-MSH antagonize feeding behavior stimulated by kappa opiate agonists

1986 • 240 citations

Nonopiate Effects of Dynorphin and Des-Tyr-Dynorphin

1982 • 235 citations

The Melanotropic Peptides

1988 • 168 citations

Interaction between acth fragments, brain opiate receptors and morphine-induced analgesia

1976 • 164 citations

Action of Light on Frog Pigment Cells in Culture

1990 • 160 citations

Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction.

1996 • 138 citations

Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism

1992 • 120 citations

Non-opioid effects of dynorphins: possible role of the NMDA receptor

1994 • 99 citations

The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin

1995 • 95 citations

α-MSH and other ACTH fragments improve cardiovascular function and survival in experimental hemorrhagic shock

1986 • 94 citations

Attenuation of morphine tolerance and dependence by α-melanocyte stimulating hormone (α-MSH)

1979 • 88 citations

Antagonism of morphine-induced analgesia, tolerance and dependence by alpha-melanocyte-stimulating hormone.

1984 • 83 citations

Suppression by dynorphin A and [des-Tyr1]dynorphin A peptides of the expression of opiate withdrawal and tolerance in morphine-dependent mice.

1993 • 67 citations

Combinatorial diffusion assay used to identify topically active melanocyte-stimulating hormone receptor antagonists.

1995 • 67 citations

Spinal opioid systems in inflammation

1995 • 65 citations

Identification of Dynorphins as Endogenous Ligands for an Opioid Receptor-like Orphan Receptor

1995 • 49 citations

Dynorphin (1–17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects

1982 • 47 citations

Adrenocorticotropin reversal of experimental hemorrhagic shock is antagonized by morphine

1986 • 45 citations

Dynorphin A modulates acute and chronic opioid effects.

1995 • 40 citations

Induction of analgesia by central administration of ORG 2766, an analog of ACTH4–9

1981 • 39 citations

Attenuation of morphine analgesia by α-MSH, MIF-I, melatonin and naloxone in the rat

1982 • 23 citations

Characterization of non-opioid [3H]Dynorphin A-(1-13) Binding Sites in the Rat Heart

1993 • 14 citations

Structure-based search for peptide ligands that cross-react with melanocortin receptors.

1996 • 14 citations

Studies on neuropeptide Y receptors in a mouse adrenocortical cell line.

1995 • 10 citations

Dynorphin binds to neuropeptide Y and peptide YY receptors in human neuroblastoma cell lines

1994 • 9 citations

Desensitization of melanotropin receptors in COS-7 cells

1996 • 5 citations