Molecular Cascades in UV Induced Melanogenesis: A Central Role for Melanotropins?

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

1975 • 7,413 citations

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

1991 • 1,946 citations

Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 830 published cases

1987 • 1,070 citations

Xeroderma Pigmentosum

1987 • 774 citations

Mechanism of immune suppression by ultraviolet irradiation in vivo. I. Evidence for the existence of a unique photoreceptor in skin and its role in photoimmunology.

1983 • 541 citations

Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.

1988 • 489 citations

Systemic alteration induced in mice by ultraviolet light irradiation and its relationship to ultraviolet carcinogenesis.

1977 • 400 citations

Interleukin 1 gene expression in cultured human keratinocytes is augmented by ultraviolet irradiation.

1987 • 352 citations

Dermatology in General Medicine

1988 • 338 citations

Effect of Alpha- and Beta-Melanocyte Stimulating Hormones on the Skin Colour of Man

1961 • 328 citations

Effects of endothelins on signal transduction and proliferation in human melanocytes.

1991 • 269 citations

New regulators of melanin biosynthesis and the autodestruction of melanoma cells

1980 • 244 citations

Regulation of Human Melanocyte Growth, Dendricity, and Melanization by Keratinocyte Derived Factors

1989 • 237 citations

Epidemiology of Malignant Melanoma: Intermittent or Total Accumulated Exposure to the Sun?

1988 • 229 citations

Ultraviolet Light Induces Increased Circulating Interleukin-6 in Humans

1990 • 222 citations

Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells.

1986 • 215 citations

Induction of Skin Tanning by Subcutaneous Administration of a Potent Synthetic Melanotropin

1991 • 205 citations

Stimulation of Growth of Keratinocytes by Basic Fibroblast Growth Factor

1988 • 172 citations

Control of Phenotypic Expresssion of Cultured Melanoma Cells by Melanocyte Stimulating Hormones

1973 • 160 citations

UVB-Induced Melanogenesis May Be Mediated Through the MSH-Receptor System.

1989 • 120 citations

Part III: General Considerations of Skin Pigmentation: The Melanocyte: Cytology and Cytochemistry11From the Division of Dermatology, University of Oregon Medical School, Portland, Oregon and the Department of Anatomy, Emory University Medical School, Atlanta, Georgia.

1959 • 120 citations

UVB Irradiation Induces Melanocyte Increase in Both Exposed and Shielded Human Skin

1989 • 118 citations

Proopiomelanocortin expression in the skin during induced hair growth in mice

1992 • 118 citations

Mechanisms in the suppression of tumor rejection produced in mice by repeated UV irradiation.

1984 • 107 citations

Influence of Age and UV on the Populations of Dopa-positive Melanocytes in Human Skin**From the Division of Biological and Medical Sciences, Brown University, Providence, R.I., the Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Mass., and the Rhode Island Medical Center, Howard, R.I.

1969 • 101 citations

Effect of Seawater Soluble Fraction of Kerosene on Chemotaxis in a Marine Snail, Nassarius obsoletus

1973 • 89 citations

Modulation of intercellular Adhesion Molecule-1 Expression on Human Melanocytes and Melanoma Cells: Evidence for a Regulatory Role of IL-6, IL-7, TNFβ, and UVB Light

1992 • 81 citations

Methods in Neurosciences

1991 • 80 citations

Human Melanocytic Neoplasms and Their Etiologic Relationship with Sunlight

1989 • 73 citations

Ultraviolet stimulated melanogenesis by human melanocytes is augmented by di‐acyl glycerol but not TPA

1990 • 71 citations

Local and Systemic Effects on the Epidermal Melanocyte Population in UV-irradiated Mouse Skin

1979 • 66 citations

Hormonal control of melanocytes: MSH-sensitive adenyl cyclase in the Cloudman melanoma.

1973 • 66 citations

Long-Wave Ultraviolet Light Induces Phospholipase Activation in Cultured Human Epidermal Keratinocytes

1990 • 63 citations

Pigment Transfer in Mammalian Epidermis

1969 • 61 citations

Structural/functional relationships between internal and external MSH receptors: Modulation of expression in Cloudman melanoma cells by UVB radiation

1991 • 59 citations

Pigment transfer in mammalian epidermis

1969 • 58 citations

Melanocyte-keratinocyte interactions in vivo: the fate of melanosomes.

1973 • 58 citations

Melanin Monomers Within Coated Vesicles and Premelanosomes in Melanin Synthesizing Cells

1988 • 55 citations

The Effect of Ultraviolet Irradiation on Melanogenesis**From the Department of Anatomy, the Medical School, King's College, University of Durham, Newcastle upon Tyne, England.

1963 • 53 citations

Evidence suggesting that a cyclic AMP‐dependent protein kinase is a positive regulator of proliferation in Cloudman S91 melanoma cells

1979 • 48 citations

Inhibition of Skin Allograft Rejection and Acute Graft-Versus-Host Disease by Cis-Urocanic Acid

1992 • 46 citations

DIETARY HISTIDINE INCREASES MOUSE SKIN UROCANIC ACID LEVELS AND ENHANCES UVB‐INDUCED IMMUNE SUPPRESSION OF CONTACT HYPERSNSITIVITY

1991 • 40 citations

Interactions between ultraviolet light and interleukin-1 on MSH binding in both mouse melanoma and human squamous carcinoma cells

1991 • 35 citations

Internal binding sites for MSH: Analyses in wild‐type and variant Cloudman melanoma cells

1990 • 35 citations

[Modification of alpha-MSH by UVA irradiation of the skin].

1983 • 33 citations

Identification and Characterization of Melanotropin Binding Proteins from M2R Melanoma Cells by Covalent Photoaffinity Labeling*

1988 • 26 citations

Action of cyclic AMP on pigment donation between mammalian melanocytes and keratinocytes.

1973 • 22 citations

Photogeneration of free radicals from eumelanogenic intermediates and metabolites

1987 • 17 citations

Formation of an Ommatin Pigment from Tyrosine by Ultra-violet Irradiation

1961 • 9 citations

Enzymic and Light-Induced Conversion of 5,6-Dihydroxyindole(s) to Melanin(s)

1988 • 2 citations

Regulation of Melanogenesis at the Sub-Cellular Level in Cloudman Murine Melanoma Cells

1992 • 1 citations