Immunohistochemical Localization of the Pro-Peptide Processing Enzymes PC1/PC3 and PC2 in the Human Anal Canal

Histology for Pathologists

1992 • 820 citations

The chromogranins A and B: The first 25 years and future perspectives

1992 • 653 citations

Neuropeptides in perspective: The last ten years

1991 • 620 citations

Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2.

1990 • 579 citations

Cloning and Primary Sequence of a Mouse Candidate Prohormone Convertase PC1 Homologous to PC2, Furin, and Kex2: Distinct Chromosomal Localization and Messenger RNA Distribution in Brain and Pituitary Compared to PC2

1991 • 475 citations

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans.

1991 • 449 citations

Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease.

1989 • 386 citations

Derivation of mouse intestinal crypts from single progenitor cells

1985 • 330 citations

Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary.

1992 • 256 citations

Gene expression of prohormone and proprotein convertases in the rat CNS: a comparative in situ hybridization analysis

1993 • 236 citations

cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells.

1993 • 223 citations

Testicular expression of PC4 in the rat: molecular diversity of a novel germ cell-specific Kex2/subtilisin-like proprotein convertase.

1992 • 203 citations

Molecular anatomy of the neuro-immune connection

1991 • 202 citations

Identification and Functional Expression of a New Member of the Mammalian Kex2-Like Processing Endoprotease Family: Its Striking Structural Similarity to PACE41

1993 • 185 citations

Proprotein conversion is determined by a multiplicity of factors including convertase processing, substrate specificity, and intracellular environment. Cell type-specific processing of human prorenin by the convertase PC1.

1992 • 149 citations

Mammalian Neural and Endocrine Pro-Protein and Pro-Hormone Convertases Belonging to the Subtilisin Family of Serine Proteinases

1991 • 96 citations

Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets.

1994 • 87 citations

Neural and Pharmacologic Factors Affecting Motility of the Internal Anal Sphincter

1983 • 73 citations

Furin: The Prototype Mammalian Subtilisin-Like Proprotein-Processing Enzyme

1991 • 58 citations

The neuro-B cell link of peptidergic innervation in the Bursa Fabricii

1991 • 51 citations

Renewal of enterochromaffin cells in the rat caecum

1992 • 31 citations

Distribution and chemical phenotypes of neuroendocrine cells in the human anal canal

1994 • 24 citations

Neuroanatomical and Functional Studies of Peptide Precursor-Processing Enyzmes

1991 • 24 citations

Regional specificities in the distribution, chemical phenotypes, and coexistence patterns of neuropeptide containing nerve fibres in the human anal canal

1993 • 13 citations

Dual presence of chromogranin A-like immunoreactivity in a population of endocrine-like cells and in nerve fibers in the human anal canal

1991 • 11 citations

Distribution and coexistence of chromogranin A-, serotonin-and pancreastatin-like immunoreactivity in endocrine-like cells of the human anal canal

1992 • 10 citations

Influence of Peptides on Anorectal Function

1990 • 9 citations