Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1998 • 14,674 citations

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

2000 • 4,834 citations

Role for a bidentate ribonuclease in the initiation step of RNA interference

2001 • 4,804 citations

HOW CELLS RESPOND TO INTERFERONS

1998 • 3,937 citations

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

1999 • 3,775 citations

RNA interference is mediated by 21- and 22-nucleotide RNAs

2001 • 3,271 citations

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

2000 • 2,945 citations

A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA

2001 • 2,623 citations

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

2000 • 1,767 citations

Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi

2001 • 1,492 citations

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

2001 • 1,430 citations

The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans

1999 • 1,286 citations

On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing

2001 • 1,282 citations

Algorithms and Thermodynamics for RNA Secondary Structure Prediction: A Practical Guide

1999 • 1,146 citations

Use of dsRNA-Mediated Genetic Interference to Demonstrate that frizzled and frizzled 2 Act in the Wingless Pathway

1998 • 1,116 citations

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

2001 • 1,055 citations

ATP Requirements and Small Interfering RNA Structure in the RNA Interference Pathway

2001 • 1,008 citations

Gene silencing as an adaptive defence against viruses

2001 • 985 citations

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

2000 • 867 citations

Targeted mRNA degradation by double-stranded RNA in vitro

1999 • 845 citations

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways

2000 • 832 citations

mut-7 of C. elegans, Required for Transposon Silencing and RNA Interference, Is a Homolog of Werner Syndrome Helicase and RNaseD

1999 • 745 citations

RNA interference—2001

2001 • 698 citations

RNA Silencing in Plants--Defense and Counterdefense

2001 • 605 citations

The Serine Protease Omi/HtrA2 Regulates Apoptosis by Binding XIAP through a Reaper-like Motif

2002 • 533 citations

Cell biology of tissue factor, the principal initiator of blood coagulation

1996 • 418 citations

Mitochondrial endonuclease G is important for apoptosis in C. elegans

2001 • 416 citations

Functional Anatomy of a dsRNA Trigger

2000 • 397 citations

RNAi as Random Degradative PCR

2001 • 370 citations

RNA interference: listening to the sound of silence.

2001 • 365 citations

RNA Interference and Small Interfering RNAs

2001 • 299 citations

The major mRNA-associated protein YB-1 is a potent 5' cap-dependent mRNA stabilizer

2001 • 269 citations

dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference

2000 • 232 citations

RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposon-derived 24-26-nucleotide RNAs.

2001 • 178 citations

A Short Primer on RNAi

2001 • 176 citations

Functional characterization of SR and SR-related genes in Caenorhabditis elegans

2000 • 166 citations

A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements

2001 • 165 citations

Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development

2001 • 119 citations

Short 5′-phosphorylated double-stranded RNAs induce RNA interference in Drosophila

2001 • 104 citations

Studies on tissue thromboplastin

1966 • 71 citations

Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymes

2000 • 67 citations

Use of cDNA subtraction and RNA interference screens in combination reveals genes required for germ-line development in Caenorhabditis elegans

2001 • 64 citations

Opposite sorting of tissue factor in human umbilical vein endothelial cells and Madin-Darby canine kidney epithelial cells

1996 • 32 citations

Characterization of PSKH1, a Novel Human Protein Serine Kinase with Centrosomal, Golgi, and Nuclear Localization

2000 • 26 citations

Effects of Binding of Ligand (FVIIa) to Induced Tissue Factor in Human Endothelial Cells

2000 • 6 citations