Short 5′-phosphorylated double-stranded RNAs induce RNA interference in Drosophila

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1998 • 14,674 citations

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

Role for a bidentate ribonuclease in the initiation step of RNA interference

2001 • 4,804 citations

RNA interference is mediated by 21- and 22-nucleotide RNAs

2001 • 3,271 citations

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

2000 • 2,945 citations

RNAi

2000 • 2,596 citations

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

2000 • 1,767 citations

Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA

1998 • 1,121 citations

Use of dsRNA-Mediated Genetic Interference to Demonstrate that frizzled and frizzled 2 Act in the Wingless Pathway

1998 • 1,116 citations

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

2001 • 1,055 citations

Gene silencing as an adaptive defence against viruses

2001 • 985 citations

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

2000 • 867 citations

Transcriptional silencing and promoter methylation triggered by double-stranded RNA

2000 • 866 citations

Post-transcriptional gene silencing by double-stranded RNA

2001 • 833 citations

RNA silencing as a plant immune system against viruses

2001 • 752 citations

RNA interference—2001

2001 • 698 citations

Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana

2000 • 647 citations

RNA Silencing in Plants--Defense and Counterdefense

2001 • 605 citations

RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans

1998 • 561 citations

On the phenotype and development of mutants of early neurogenesis inDrosophila melanogaster

1983 • 493 citations

Double-Stranded RNA as a Template for Gene Silencing

2000 • 421 citations

Functional Anatomy of a dsRNA Trigger

2000 • 397 citations

RNA: Guiding Gene Silencing

2001 • 375 citations

Isolation of quelling-defective ( qde ) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa

1997 • 307 citations

Transcriptional and posttranscriptional gene silencing are mechanistically related

2001 • 266 citations

Replicating potato spindle tuber viroid RNA is accompanied by short RNA fragments that are characteristic of post-transcriptional gene silencing

2001 • 242 citations

Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos

2000 • 239 citations

Function, mechanism and regulation of bacterial ribonucleases

1999 • 237 citations

Maternal effects of zygotic mutants affecting early neurogenesis inDrosophila

1982 • 66 citations

Resistance of RNA-mediated TGS to HC-Pro, a viral suppressor of PTGS, suggests alternative pathways for dsRNA processing

2001 • 57 citations