Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Role for a bidentate ribonuclease in the initiation step of RNA interference

2001 • 4,804 citations

HOW CELLS RESPOND TO INTERFERONS

1998 • 3,937 citations

RNA interference is mediated by 21- and 22-nucleotide RNAs

2001 • 3,271 citations

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

2000 • 2,945 citations

RNAi

2000 • 2,596 citations

Loss of a-Type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy

1999 • 1,180 citations

Transcriptional silencing and promoter methylation triggered by double-stranded RNA

2000 • 866 citations

Post-transcriptional gene silencing by double-stranded RNA

2001 • 833 citations

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways

2000 • 832 citations

CpG methylation, chromatin structure and gene silencing---a three-way connection

1998 • 791 citations

Specific interference with gene function by double-stranded RNA in early mouse development

1999 • 719 citations

RNA interference—2001

2001 • 698 citations

RNA-triggered gene silencing

1999 • 623 citations

Interactions between double-stranded RNA regulators and the protein kinase DAI.

1992 • 475 citations

Inhibition of cell-free protein synthesis by pppA2′ p5′ A2′ p5′ A: a novel oligonucleotide synthesized by interferon-treated L cell extracts

1978 • 435 citations

Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference

2000 • 412 citations

Functional Anatomy of a dsRNA Trigger

2000 • 397 citations

Guidebook to the cytoskeletal and motor proteins

1994 • 374 citations

RNA Interference and Small Interfering RNAs

2001 • 299 citations

Structural requirements of double-stranded RNA for the activation of 2‘,5‘-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells.

1979 • 263 citations

RNA-directed DNA methylation.

2000 • 258 citations

dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference

2000 • 232 citations

Guidebook to the Cytoskeletal and Motor Proteins

1999 • 209 citations

Nucleocytoplasmic Shuttling Factors Including Ran and CRM1 Mediate Nuclear Export of NFAT In Vitro

1998 • 175 citations

Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes

2000 • 116 citations

Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice

1999 • 114 citations

Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target

2000 • 105 citations

Replicating satellite RNA induces sequence-specific DNA methylation and truncated transcripts in plants

2001 • 97 citations

Transcriptional and Posttranscriptional Silencing of Rodent α1(I) Collagen by a Homologous Transcriptionally Self-Silenced Transgene

1999 • 50 citations

Induction of nuclear lamins A/C in macrophages in in vitro cultures of rat bone marrow precursor cells and human blood monocytes, and in macrophages elicited in vivo by thioglycollate stimulation

1990 • 41 citations