The role of cytokines in classical Hodgkin lymphoma

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group [see comments]

1994 • 6,495 citations

Interleukin-10 and the Interleukin-10 Receptor

2001 • 6,422 citations

World Health Organization Classification of Tumours

2002 • 5,829 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues

2002 • 4,781 citations

Chemokines

2000 • 3,773 citations

The TNF and TNF Receptor Superfamilies

2001 • 3,533 citations

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues

2003 • 2,031 citations

JAKS AND STATS: Biological Implications

1998 • 1,788 citations

STATs in oncogenesis

2000 • 1,723 citations

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

1999 • 1,715 citations

Germinal Centers

1994 • 1,680 citations

Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

1996 • 1,618 citations

Essential role of Stat6 in IL-4 signalling

1996 • 1,563 citations

The Molecular Cell Biology of Interferon-gamma and its Receptor

1993 • 1,323 citations

Interleukin-6 family of cytokines and gp130

1995 • 1,314 citations

TUMOR NECROSIS FACTOR RECEPTOR AND Fas SIGNALING MECHANISMS

1999 • 1,309 citations

The CD40 Antigen and its Ligand

1994 • 1,259 citations

THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses

1998 • 1,253 citations

Aberrant rel/nfkb genes and activity in human cancer

1999 • 1,127 citations

The cytokine handbook

1994 • 1,121 citations

In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death

1997 • 1,091 citations

Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

1993 • 1,084 citations

Constitutive Nuclear Factor κB Activity Is Required for Survival of Activated B Cell–like Diffuse Large B Cell Lymphoma Cells

2001 • 1,035 citations

Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

1998 • 918 citations

Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1

2001 • 896 citations

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1994 • 888 citations

Interleukin-4: a prototypic immunoregulatory lymphokine

1991 • 878 citations

Interleukin-5, eosinophils, and disease

1992 • 874 citations

[Hodgkin's disease].

1988 • 829 citations

Eosinophilia

1998 • 802 citations

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

1997 • 780 citations

Interleukin-5, eosinophils, and disease

1992 • 771 citations

Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine

1999 • 710 citations

An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2–dominated inflammatory response

1999 • 601 citations

The IL-2 Receptor Complex: Its Structure, Function, and Target Genes

1993 • 601 citations

Tumor necrosis factor receptor-associated factors (TRAFs)—a family of adapter proteins that regulates life and death

1998 • 597 citations

Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.

1993 • 565 citations

CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

1993 • 541 citations

Hodgkin and Reed-Sternberg cells represent an expansion of a single clone originating from a germinal center B-cell with functional immunoglobulin gene rearrangements but defective immunoglobulin transcription

2000 • 493 citations

CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy

1995 • 446 citations

Tumor Necrosis Factor Receptor-Associated Factor (TRAF) Family: Adapter Proteins That Mediate Cytokine Signaling

2000 • 436 citations

Mimicry of CD40 Signals by Epstein-Barr Virus LMP1 in B Lymphocyte Responses

1999 • 430 citations

Schistosome Infection of Transgenic Mice Defines Distinct and Contrasting Pathogenic Roles for IL-4 and IL-13: IL-13 Is a Profibrotic Agent

2000 • 402 citations

High Expression of the CC Chemokine TARC in Reed-Sternberg Cells

1999 • 379 citations

Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IκBα

1999 • 347 citations

Latent membrane protein 1of Epstein-Barr virus interacts with JAK3 and activates STAT proteins

1999 • 346 citations

High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells

1996 • 328 citations

Fibrosis of the Lung and Other Tissues: New Concepts in Pathogenesis and Treatment

2001 • 325 citations

THE ORIGIN OF HODGKIN AND REED/STERNBERG CELLS IN HODGKIN'S DISEASE

1998 • 314 citations

The biology of Stat4 and Stat6

2000 • 310 citations

Epstein-Barr virus and Hodgkin's disease. A correlative in situ hybridization and polymerase chain reaction study.

1991 • 304 citations

Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines

1994 • 303 citations

Interleukin 13 is a B cell stimulating factor.

1994 • 298 citations

Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

2002 • 291 citations

Clonal Deleterious Mutations in the Iκbα Gene in the Malignant Cells in Hodgkin's Lymphoma

2000 • 287 citations

Interleukin 13 Is Secreted by and Stimulates the Growth of Hodgkin and Reed-Sternberg Cells

1999 • 285 citations

Molecular mechanisms of constitutive NF-κB/Rel activation in Hodgkin/Reed-Sternberg cells

1999 • 285 citations

Inducible Expression of a Th2-Type CC Chemokine Thymus- and Activation-Regulated Chemokine by Human Bronchial Epithelial Cells

2000 • 285 citations

Soluble cytokine receptors

1996 • 282 citations

STCP-1 (MDC) CC Chemokine Acts Specifically on Chronically Activated Th2 Lymphocytes and Is Produced by Monocytes on Stimulation with Th2 Cytokines IL-4 and IL-13

1998 • 275 citations

Soluble IL-2 receptor in rheumatoid arthritis. Correlation with disease activity, IL-1 and IL-2 inhibition.

1988 • 274 citations

Overexpression of I Kappa B Alpha Without Inhibition of NF-κB Activity and Mutations in the I Kappa B Alpha Gene in Reed-Sternberg Cells

1999 • 267 citations

Transcription factor NF-κB is constitutively activated in acute lymphoblastic leukemia cells

2000 • 266 citations

Constitutive NF-κB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells

2001 • 263 citations

Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice.

1996 • 243 citations

STAT3 is constitutively activated in Hodgkin cell lines

2001 • 220 citations

Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophilia

1990 • 220 citations

Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts.

2000 • 217 citations

Expression of functional CD40 antigen on Reed-Sternberg cells and Hodgkin's disease cell lines

1995 • 212 citations

Jak3 Is Associated with CD40 and Is Critical for CD40 Induction of Gene Expression in B Cells

1997 • 207 citations

CD40 molecules induce down-modulation and endocytosis of T cell surface T cell-B cell activating molecule/CD40-L. Potential role in regulating helper effector function.

1994 • 205 citations

Divergent Effects of Interleukin-4 and Interferon-γ on Macrophage-Derived Chemokine Production: An Amplification Circuit of Polarized T Helper 2 Responses

1998 • 203 citations

Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

2001 • 200 citations

Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells

1996 • 194 citations

Frequent expression of interleukin-10 by Epstein-Barr virus-harboring tumor cells of Hodgkin's disease

1996 • 193 citations

Recent Results on the Biology of Hodgkin and Reed-Sternberg cells: II. Continuous Cell Lines

1993 • 190 citations

Signal Transducer and Activator of Transcription 6 Controls Chemokine Production and T Helper Cell Type 2 Cell Trafficking in Allergic Pulmonary Inflammation

2001 • 182 citations

Distribution and phenotype of Epstein-Barr virus-harboring cells in Hodgkin's disease

1992 • 179 citations

Local suppression of Epstein-Barr virus (EBV)-specific cytotoxicity in biopsies of EBV-positive Hodgkin's disease

1995 • 175 citations

Interleukin-9 expression in human malignant lymphomas: unique association with Hodgkin's disease and large cell anaplastic lymphoma

1991 • 173 citations

Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed- Sternberg cells of a Hodgkin's lymphoma patient

1996 • 170 citations

JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen‐activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells

2000 • 170 citations

Serum interleukin 6 levels are elevated in lymphoma patients and correlate with survival in advanced Hodgkin's disease and with B symptoms.

1993 • 169 citations

Interleukin-13 Upregulates Eotaxin Expression in Airway Epithelial Cells by a STAT6-Dependent Mechanism

2001 • 169 citations

In situ immunologic characterization of cellular constituents in lymph nodes and spleens involved by Hodgkin's disease

1982 • 169 citations

JAK3, STAT, and MAPK Signaling Pathways as Novel Molecular Targets for the Tyrphostin AG-490 Regulation of IL-2-Mediated T Cell Response

1999 • 164 citations

Single-cell analysis of Hodgkin and Reed-Sternberg cells: molecular heterogeneity of gene expression and p53 mutations

1993 • 159 citations

CD40 ligand is constitutively expressed in a subset of T cell lymphomas and on the microenvironmental reactive T cells of follicular lymphomas and Hodgkin's disease.

1995 • 156 citations

Analysis of major histocompatibility complex class I expression on Reed- Sternberg cells in relation to the cytotoxic T-cell response in Epstein- Barr virus-positive and -negative Hodgkin's disease

1996 • 152 citations

Hodgkin/Reed-Sternberg Cells Induce Fibroblasts to Secrete Eotaxin, a Potent Chemoattractant for T Cells and Eosinophils

1999 • 152 citations

Differential regulation of IL-13 and IL-4 production by human CD8⁺ and CD4⁺ T_h0, T_h1 and T_h2 T cell clones and EBV-transformed B cells

1995 • 145 citations

Differential Chemokine Expression in Tissues Involved by Hodgkin’s Disease: Direct Correlation of Eotaxin Expression and Tissue Eosinophilia

1999 • 142 citations

Activated Cytotoxic T Cells as Prognostic Marker in Hodgkin's Disease

1997 • 138 citations

Human eosinophils express functional CD30 ligand and stimulate proliferation of a Hodgkin's disease cell line

1996 • 137 citations

Expression of interleukin-6 and interleukin-6 receptor in Hodgkin's disease

1991 • 133 citations

Functional expression of receptor activator of nuclear factor κB in Hodgkin disease cell lines

2001 • 133 citations

Mast cells express functional CD30 ligand and are the predominant CD30L‐positive cells in Hodgkin's disease

2001 • 130 citations

STAT6 Mediates Eotaxin-1 Expression in IL-4 or TNF-α-Induced Fibroblasts

2001 • 129 citations

Defective IκBα in Hodgkin cell lines with constitutively active NF-κB

1998 • 129 citations

EBV infection patterns in Hodgkin's disease and normal lymphoid tissue: expression and cellular localization of EBV gene products

1992 • 126 citations

The immunophenotype of reed-sternberg cells. A study of 50 cases of Hodgkin' disease using fixed frozen tissues

1989 • 126 citations

Differential Chemokine Expression in Tissues Involved by Hodgkin’s Disease: Direct Correlation of Eotaxin Expression and Tissue Eosinophilia

1999 • 125 citations

Lymphotoxin, tumour necrosis factor and interleukin‐6 gene transcripts are present in Hodgkin and Reed‐Sternberg cells of most Hodgkin's disease cases

1993 • 105 citations

Characterization of NF-κB Expression in Hodgkin's Disease: Inhibition of Constitutively Expressed NF-κB Results in Spontaneous Caspase-Independent Apoptosis in Hodgkin and Reed-Sternberg Cells

2001 • 104 citations

Role of IL-9 in the pathophysiology of allergic diseases

2001 • 102 citations

Cytokine expression in T-cell lymphomas and Hodgkin's disease. Its possible implication in autocrine or paracrine production as a potential basis for neoplastic growth.

1991 • 98 citations

Expression and function of CD40 on Hodgkin and Reed-Sternberg cells and the possible relevance for Hodgkin's disease

1994 • 96 citations

Interleukin‐13 and interleukin‐13 receptor in Hodgkin's disease: possible autocrine mechanism and involvement in fibrosis

2001 • 92 citations

Cutting Edge: Differential Expression of Chemokines in Th1 and Th2 Cells Is Dependent on Stat6 But Not Stat4

2000 • 90 citations

Epstein-Barr virus-specific cytotoxic T lymphocyte responses in the blood and tumor site of Hodgkin's disease patients: implications for a T-cell-based therapy.

2001 • 90 citations

Quantitative immunohistochemical analysis of cytokine profiles in Epstein-Barr virus-positive and -negative cases of Hodgkin's disease

2000 • 88 citations

Cytokine Production (IL-1α, IL-1β, and TNFα) and Endothelial Cell Activation (ELAM-1 and HLA-DR) in Reactive Lymphadenitis, Hodgkin's Disease, and in Non-Hodgkin's Lymphomas: An Immunocytochemical Study

1990 • 85 citations

Distribution of lymphocytes with interleukin-2 receptors (TAC antigens) in reactive lymphoproliferative processes, Hodgkin's disease, and non-Hodgkin's lymphomas. An immunohistologic study of 300 cases.

1987 • 85 citations

The impact of Hodgkin's disease on the immune system.

1990 • 84 citations

Immunohistochemical evidence of a role for transforming growth factor beta in the pathogenesis of nodular sclerosing Hodgkin's disease.

1990 • 84 citations

Expression of cytokine and chemokine genes in Epstein-Barr virus-associated nasopharyngeal carcinoma: comparison with Hodgkin's disease

2001 • 84 citations

Epstein-Barr virus and hodgkin’s disease

1993 • 84 citations

Clinical Correlates of Elevated Serum Levels of Interleukin-6 in Patients with Untreated Hodgkin's Disease

1997 • 83 citations

IL-2 receptor expression in human lymphoid lesions. Immunohistochemical study of 166 cases.

1987 • 83 citations

Tumor Necrosis Factor Receptor-Associated Factor 1 Is Overexpressed in Reed-Sternberg Cells of Hodgkin’s Disease and Epstein-Barr Virus-Transformed Lymphoid Cells

1999 • 83 citations

Interleukin-13 in Combination With CD40 Ligand Potently Inhibits Apoptosis in Human B Lymphocytes: Upregulation of Bcl-xL and Mcl-1

1997 • 81 citations

Induction of Subcutaneous Tissue Fibrosis in Newborn Mice by Transforming Growth Factor β—Simultaneous Application with Basic Fibroblast Growth Factor Causes Persistent Fibrosis

1997 • 78 citations

Eosinophils are the major source of transforming growth factor-beta 1 in nodular sclerosing Hodgkin's disease.

1993 • 77 citations

CD30 ligand expression in nonmalignant and Hodgkin's disease-involved lymphoid tissues.

1996 • 76 citations

TARC, a CC Chemokine, Is Frequently Expressed in Classic Hodgkin's Lymphoma But Not in NLP Hodgkin's Lymphoma, T-Cell-Rich B-Cell Lymphoma, and Most Cases of Anaplastic Large Cell Lymphoma

2001 • 73 citations

Recombinant CD30 ligand and CD40 ligand share common biological activities on Hodgkin and Reed‐Sternberg cells

1995 • 71 citations

CD40 expression in Hodgkin's disease.

1994 • 70 citations

L-428 nodular sclerosing Hodgkin's cell secretes a unique transforming growth factor-beta active at physiologic pH.

1988 • 69 citations

Production of tumor necrosis factor-alpha and lymphotoxin by cells of Hodgkin's neoplastic cell lines HDLM-1 and KM-H2.

1989 • 68 citations

Soluble IL-2 receptor as an agent of serum-mediated suppression in human visceral leishmaniasis.

1991 • 67 citations

Expression of interleukin-1 in Reed-Sternberg cells and neoplastic cells from true histiocytic malignancies.

1986 • 64 citations

Transforming growth factor beta 1 messenger RNA in Reed-Sternberg cells in nodular sclerosing Hodgkin's disease.

1995 • 64 citations

CC chemokines and the receptors CCR3 and CCR5 are differentially expressed in the nonneoplastic leukocytic infiltrates of Hodgkin disease

2001 • 63 citations

Frequent expression of IL-7 gene transcripts in tumor cells of classical Hodgkin's disease.

1995 • 63 citations

Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines.

1994 • 62 citations

Production of transforming growth factor-beta activity by Ki-1 positive lymphoma cells and analysis of its role in the regulation of Ki-1 positive lymphoma growth.

1988 • 62 citations

Expression of the macrophage growth factor, CSF-1 and its receptor c-fms by a Hodgkin's disease-derived cell line and its variants.

1990 • 61 citations

Serum cytokine levels correlate with clinical parameters in Hodgkin’s disease

1995 • 61 citations

Hodgkin disease: pharmacologic intervention of the CD40-NFκB pathway by a protease inhibitor

2000 • 57 citations

Tumor necrosis factor receptors in lymphoid tissues and lymphomas. Source and site of action of tumor necrosis factor alpha.

1991 • 56 citations

Immune reactions in classical Hodgkin's lymphoma.

1999 • 55 citations

Interleukin-8 in Hodgkin's disease. Preferential expression by reactive cells and association with neutrophil density.

1996 • 55 citations

Tumor necrosis factor/cachectin and lymphotoxin gene expression in lymph nodes from lymphoma patients

1990 • 53 citations

High serum and ascitic soluble interleukin-2 receptor alpha levels in advanced epithelial ovarian cancer [see comments]

1993 • 51 citations

Macrophage-Derived Chemokine Expression in Classical Hodgkin's Lymphoma: Application of Tissue Microarrays

2001 • 51 citations

Low serum interleukin-2 receptor levels correlate with a good prognosis in patients with Hodgkin's lymphoma

1991 • 51 citations

Modulation of interleukin-6 expression in Hodgkin and Reed-Sternberg cells by Epstein-Barr virus

1997 • 51 citations

Amplification of TCRβ gene rearrangements from micromanipulated single cells: T cells rosetting around Hodgkin and Reed-Sternberg cells in Hodgkin's disease are polyclonal

1998 • 50 citations

Tumor necrosis factor alpha and lymphotoxin production in Hodgkin's disease.

1990 • 49 citations

Cytokines in Hematopoiesis

1998 • 49 citations

Lymph node T cells in Hodgkin's disease: analysis of suspensions with monoclonal antibody and rosetting techniques

1982 • 47 citations

Interleukin-6, but not interleukin-4, is expressed by Reed-Sternberg cells in Hodgkin's disease with or without histologic features of Castleman's disease.

1992 • 47 citations

T-lymphocyte subpopulations in B-cell-derived non-hodgkin's lymphomas and hodgkin's disease

1984 • 46 citations

Autocrine Growth Regulation of CD30 Ligand in CD30-Expressing Reed-Sternberg Cells: Distinction Between Hodgkin's Disease and Anaplastic Large Cell Lymphoma

2000 • 46 citations

Displacement of T Lymphocytes with the ‘Helper/Inducer’ Phenotype from Peripheral Blood to Lymphoid Organs in Untreated Patients with Hodgkin's Disease

1983 • 43 citations

B- and T-lymphocytes in Hodgkin's disease. An immunohistochemical study utilizing heterologous and monoclonal antibodies

1985 • 43 citations

Interleukin-12 expression in human lymphomas and nonneoplastic lymphoid disorders

1995 • 40 citations

Heterogeneity of interleukin 1 production in cultured Reed-Sternberg cell lines HDLM-1, HDLM-1d, and KM-H2.

1989 • 39 citations

Production of multiple cytokines by Hodgkin's disease derived cell lines

1992 • 38 citations

Tumor necrosis factor/cachectin and lymphotoxin gene expression in lymph nodes from lymphoma patients

1990 • 37 citations

High serum and ascitic soluble interleukin-2 receptor alpha levels in advanced epithelial ovarian cancer [see comments]

1993 • 36 citations

Expression of the tumour necrosis factor receptor-associated factors 1 and 2 in Hodgkin's disease

2001 • 36 citations

Serum levels of soluble interleukin-2 receptor in Hodgkin disease. Relationship with clinical stage, tumor burden, and treatment outcome

1993 • 36 citations

Potentiation of fibroblast growth by nodular sclerosing Hodgkin's disease cell cultures

1982 • 35 citations

Increased levels of circulating interleukin‐6 in patients with hodgkin's disease

1991 • 34 citations

Expression of the Tumor Necrosis Factor Receptor-Associated Factors (TRAFs) 1 and 2 is a Characteristic Feature of Hodgkin and Reed-Sternberg Cells

2000 • 33 citations

Antiapoptotic marker, Bcl-XL, expression on Reed-Sternberg cells of Hodgkin's disease using a novel monoclonal marker, YTH-2H12

1999 • 32 citations

Suppression of an IL-13 Autocrine Growth Loop in a Human Hodgkin/Reed-Sternberg Tumor Cell Line by a Novel IL-13 Antagonist

2001 • 30 citations

in situ expression of the IL‐I‐α and tnf‐α genes by reed‐sternberg cells in Hodgkin's disease

1992 • 29 citations

Basic Fibroblast Growth Factor and Fibrosis in Hodgkin's Disease

1999 • 28 citations

Cytokine production (IL-1 alpha, IL-1 beta, and TNF alpha) and endothelial cell activation (ELAM-1 and HLA-DR) in reactive lymphadenitis, Hodgkin's disease, and in non-Hodgkin's lymphomas. An immunocytochemical study.

1990 • 28 citations

The correlation of Epstein-Barr virus expression and lymphocyte subsets with the clinical presentation of nodular sclerosing Hodgkin disease

2001 • 27 citations

Expression of interleukin-2R alpha and interleukin-2R beta in Hodgkin's disease.

1993 • 26 citations

Lack of effect of colony-stimulating factors, interleukins, interferons, and tumor necrosis factor on the growth and differentiation of cultured Reed-Sternberg cells. Comparison with effects of phorbol ester and retinoic acid.

1990 • 26 citations

Interleukin-4 is an autocrine growth factor secreted by the L-428 Reed- Sternberg cell

1992 • 26 citations

Serum concentrations of cytokines in patients with Hodgkin's disease

1994 • 24 citations

CD8+ T Cells in Hodgkin’s Disease Tumor Tissue Are a Polyclonal Population with Limited Clonal Expansion but Little Evidence of Selection by Antigen

2000 • 24 citations

Hyperproduction of IgE and T-Cell Dysfunction in Hodgkin’s Disease

1980 • 24 citations

Potentiation of fibroblast growth by nodular sclerosing Hodgkin's disease cell cultures

1982 • 23 citations

Expression of p55 (Tac) interleukin-2 receptor (IL-2R), but not p75 IL-2R, in cultured H-RS cells and H-RS cells in tissues.

1990 • 22 citations

Immunoenzymatic assessment of interferon-γ in hodgkin and sternberg-reed cells

1990 • 21 citations

Expression of Membrane-Associated Macrophage Colony-Stimulating Factor (M-CSF) in Hodgkin's Disease and Other Hematologic Malignancies

1999 • 21 citations

Immunoprecipitation of the interleukin‐2 receptor from Hodgkin's disease derived cell lines by monoclonal antibodies

1987 • 20 citations

CD40-ligation-mediated protection from apoptosis of a Fas-sensitive Hodgkin's-disease-derived cell line

1998 • 19 citations

Anti-interleukin-1 reactive cells in Hodgkin's disease

1987 • 18 citations

Analysis of regulation of T‐cell responses by soluble inhibitory factors from the sera of patients with Hodgkin's disease

1992 • 14 citations

Biological Basis of Angiogenesis and Vascular Remodeling. Transforming growth factor-.BETA. and its receptors.

1996 • 14 citations

High affinity IL-2 receptors on a Hodgkin's derived cell line

1990 • 13 citations

Hypergammaglobulnaemia E in Hodgkin’s Disease and Its Relationship to Atopy or a Familial Predisposition to Atopy

1981 • 13 citations

Expression of B7 (CD80) and CD40 antigens and the CD40 ligand in Hodgkin's disease is independent of latent Epstein--Barr virus infection

1995 • 12 citations

Interleukin-1 and tumor necrosis factor-alpha in the Reed-Sternberg cells of Hodgkin's disease. Correlation with clinical and morphological "inflammatory" features.

1996 • 12 citations

Immunohistochemical detection of cells positive for colony-stimulating factor 1 in lymph nodes from reactive lymphadenitis, and Hodgkin's disease.

1992 • 11 citations

Lack of CSF-1 receptor message in Reed-Sternberg cells.

1989 • 4 citations

Deleted Work

1955 • 0 citations