Expression of interleukin-6 and interleukin-6 receptor in Hodgkin's disease

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

The biology of interleukin-6

1989 • 1,964 citations

The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells

1985 • 1,817 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

1987 • 1,667 citations

Cloning and Expression of the Human Interleukin-6 (BSF-2/IFNβ 2) Receptor

1988 • 1,063 citations

Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's Disease

1989 • 917 citations

Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease

1989 • 870 citations

Excessive production of interleukin 6/B cell stimulatory factor‐2 in rheumatoid arthritis

1988 • 793 citations

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells.

1988 • 791 citations

Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6

1989 • 775 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

IgG1 plasmacytosis in interleukin 6 transgenic mice.

1989 • 597 citations

B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes.

1988 • 537 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes.

1988 • 382 citations

Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production.

1987 • 363 citations

B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells.

1987 • 357 citations

Structural analysis of the sequence coding for an inducible 26‐kDa protein in human fibroblasts

1986 • 343 citations

Regulation of BSF-2/IL-6 production by human mononuclear cells. Macrophage-dependent synthesis of BSF-2/IL-6 by T cells.

1988 • 286 citations

Monocyte-Derived Human B-Cell Growth Factor Identified as Interferon-β ₂ (BSF-2, IL-6)

1988 • 281 citations

Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophilia

1990 • 220 citations

Human β ₂ Interferon and B-Cell Differentiation Factor BSF-2 Are Identical

1987 • 204 citations

Immunoglobulin gene rearrangements in Hodgkin's disease

1986 • 194 citations

Characterization of IL-6 receptor expression by monoclonal and polyclonal antibodies.

1989 • 179 citations

Interleukin-HP1, a T cell-derived hybridoma growth factor that supports the in vitro growth of murine plasmacytomas.

1987 • 174 citations

Rearranged antigen receptor genes in Hodgkin's disease [published erratum appears in Blood 1987 Sep;70(3):893]

1987 • 154 citations

The nature of the lymphocytes surrounding Reed-Sternberg cells in nodular lymphocyte predominance and in other types of Hodgkin's disease.

1989 • 142 citations

Interleukin-6 immunoreactivity in human tumors.

1989 • 136 citations

Involvement of the bcl-2 Gene in Hodgkin's Disease

1990 • 126 citations

Rearranged antigen receptor genes in Hodgkin's disease [published erratum appears in Blood 1987 Sep;70(3):893]

1987 • 104 citations

Immunophenotypes of Reed-Sternberg cells: a study of 19 cases of Hodgkin's disease in plastic-embedded sections

1989 • 84 citations

Interleukin-6 (B-cell stimulatory factor 2)-dependent growth of a Lennert's lymphoma-derived T-cell line (KT-3)

1988 • 79 citations

L-428 nodular sclerosing Hodgkin's cell secretes a unique transforming growth factor-beta active at physiologic pH.

1988 • 69 citations

Production of tumor necrosis factor-alpha and lymphotoxin by cells of Hodgkin's neoplastic cell lines HDLM-1 and KM-H2.

1989 • 68 citations

Expression of interleukin-1 in Reed-Sternberg cells and neoplastic cells from true histiocytic malignancies.

1986 • 64 citations

DNA rearrangement and constitutive expression of the interleukin 6 gene in a mouse plasmacytoma.

1990 • 64 citations

Persistent active herpes virus infection associated with atypical polyclonal lymphoproliferation (APL) and malignant lymphoma.

1989 • 61 citations

Production of colony‐stimulating factors by Hodgkin cell lines

1983 • 49 citations

Heterogeneity of interleukin 1 production in cultured Reed-Sternberg cell lines HDLM-1, HDLM-1d, and KM-H2.

1989 • 39 citations

Growth factors in Hodgkin's disease.

1982 • 36 citations

Potentiation of fibroblast growth by nodular sclerosing Hodgkin's disease cell cultures

1982 • 35 citations

Heterogeneous expression of proto‐oncogenes in Hodgkin's disease derived cell lines

1990 • 33 citations

Immunogenotyping in Hodgkin's disease

1988 • 32 citations

Human granulocyte-macrophage colony-stimulating factor purified from a Hodgkin's tumor cell line

1986 • 24 citations

Analysis of Immunoglobulin, T Cell Receptor and bcr Rearrangements in Human Malignant Lymphoma and Hodgkin’s Disease

1990 • 16 citations

Immunologic, functional and moleculargenetic properties of Hodgkin-derived cell lines

1988 • 13 citations

High affinity IL-2 receptors on a Hodgkin's derived cell line

1990 • 13 citations

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