Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Generation and Analysis of Interleukin-4 Deficient Mice

1991 • 1,266 citations

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

1987 • 1,060 citations

Molecular and biological characterization of a murine ligand for CD40

1992 • 1,029 citations

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

1988 • 939 citations

IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants.

1988 • 713 citations

Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.

1992 • 641 citations

Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.

1993 • 565 citations

Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40

1991 • 554 citations

CD21 is a ligand for CD23 and regulates IgE production

1992 • 479 citations

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

1987 • 449 citations

Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor.

1984 • 438 citations

Serum-free medium for generation and propagation of functional human cytotoxic and helper T cell clones

1984 • 392 citations

Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1.

1986 • 355 citations

Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production.

1990 • 353 citations

Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones.

1991 • 333 citations

IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma.

1988 • 315 citations

The B-cell surface protein CD72/Lyb-2 is the ligand for CDS

1991 • 305 citations

Interleukin 4 induces synthesis of IgE and IgG4 in human B cells

1989 • 300 citations

Mitogen- and IL-4-regulated expression of germ-line Ig γ2b transcripts: Evidence for directed heavy chain class switching

1988 • 277 citations

Interleukin 5 enhances interleukin 4‐induced IgE production by normal human B cells. The role of soluble CD23 antigen

1988 • 265 citations

Recombinant interleukin 4 promotes the growth of human T cells.

1987 • 252 citations

Transforming growth factor-beta directs IgA switching in human B cells.

1992 • 232 citations

Endogenous interleukin 6 plays an obligatory role in interleukin 4‐dependent human IgE synthesis

1989 • 221 citations

CD40 stimulation provides an IFN-gamma-independent and IL-4-dependent differentiation signal directly to human B cells for IgE production.

1991 • 219 citations

Recombinant interleukin-12 suppresses the synthesis of immunoglobulin E by interleukin-4 stimulated human lymphocytes.

1992 • 209 citations

Mitogen plus interleukin 4 induction of C epsilon transcripts in B lymphoid cells.

1988 • 208 citations

A simple and rapid method for the preparation of plasma membranes

1983 • 181 citations

Possible role of human lymphocyte receptor for IgE (CD23) or its soluble fragments in the in vitro synthesis of human IgE.

1988 • 175 citations

Interleukin-4 mediates CDS induction on human CD4+ T-cell clones

1988 • 163 citations

Regulation of Human B-Cell Activation and Adhesion

1991 • 161 citations

Nucleotide sequence of the human γ cytoskeletal actin mRNA: anomalous evolution of vertebrate non-muscle actin genes

1986 • 161 citations

Interleukin 8 (IL-8) selectively inhibits immunoglobulin E production induced by IL-4 in human B cells.

1992 • 113 citations

Modulation of IL-4 induced germline ε RNA synthesis in human B cells by tumor necrosis factor-α, anti-CD40 monoclonal antibodies or transforming growth factor-β correlates with levels of IgE production

1992 • 112 citations

In vitro synthesis of IgE by human lymphocytes. II. Enhancement of the spontaneous IgE synthesis by IgE-binding factors secreted by RPMI 8866 lymphoblastoid B cells.

1984 • 110 citations

Stimulation of B-cell proliferation by membrane-associated molecules from activated T cells.

1988 • 98 citations

Regulation of IgE synthesis by cytokines

1991 • 97 citations

Lymphocytes with Immunoglobulin E Fc Receptors in Patients with Atopic Disorders

1979 • 92 citations

Induction of human IgE synthesis by CD4+ T cell clones. Requirement for interleukin 4 and low molecular weight B cell growth factor.

1989 • 80 citations

Induction of isotype switching and Ig production by CD5+ and CD10+ human fetal B cells.

1992 • 69 citations

Autoreactive T cell clones specific for class I and class II HLA antigens isolated from a human chimera.

1988 • 63 citations

Membranes of activated CD4⁺ T cells expressing T cell receptor (TcR) αβ or TcR γδ induce IgE synthesis by human B cells in the presence of interleukin‐4

1992 • 43 citations

IL-2 and a contact-mediated signal provided by TCR alpha beta + or TCR gamma delta + CD4+ T cells induce polyclonal Ig production by committed human B cells. Enhancement by IL-5, specific inhibition of IgA synthesis by IL-4.

1992 • 35 citations