Dopamine Receptors: From Structure to Function

Multiple receptors for dopamine

1979 • 3,739 citations

D ₁ and D ₂ Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons

1990 • 2,873 citations

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1990 • 2,630 citations

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1996 • 2,452 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

Brain Dopamine and Reward

1989 • 1,899 citations

The neostriatal mosaic: multiple levels of compartmental organization

1992 • 1,450 citations

D1 Dopamine Receptors in Prefrontal Cortex: Involvement in Working Memory

1991 • 1,365 citations

Responses of monkey dopamine neurons to reward and conditioned stimuli during successive steps of learning a delayed response task

1993 • 1,279 citations

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.

1993 • 1,213 citations

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

1991 • 1,157 citations

Cloning and expression of a rat D2 dopamine receptor cDNA

1988 • 1,125 citations

Mesocorticolimbic dopaminergic network: functional and regulatory roles

1991 • 1,104 citations

Multiple dopamine D4 receptor variants in the human population

1992 • 967 citations

Dopamine receptor pharmacology

1994 • 959 citations

Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum.

1990 • 958 citations

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA

1991 • 859 citations

Sequence Alignment of the G-Protein Coupled Receptor Superfamily

1992 • 847 citations

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

1993 • 769 citations

Recent Advances in the Molecular Biology of Dopamine Receptors

1993 • 768 citations

Dopamine: A Prolactin-Inhibiting Hormone*

1985 • 735 citations

Alternative splicing directs the expression of two D2 dopamine receptor isoforms

1989 • 692 citations

Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin

1983 • 689 citations

Molecular cloning and expression of the gene for a human D1 dopamine receptor

1990 • 675 citations

Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin.

1992 • 672 citations

Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implications

1987 • 664 citations

The role of D1-dopamine receptor in working memory: local injections of dopamine antagonists into the prefrontal cortex of rhesus monkeys performing an oculomotor delayed-response task

1994 • 663 citations

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

1995 • 649 citations

Multiple D2 dopamine receptors produced by alternative RNA splicing

1989 • 642 citations

A family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 636 citations

Dopamine D4 receptors elevated in schizophrenia

1993 • 632 citations

The role of dopamine in drug abuse viewed from the perspective of its role in motivation

1995 • 632 citations

Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies.

1993 • 610 citations

Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia

1989 • 600 citations

Palmitoylation of the human β2-adrenergic receptor

1989 • 599 citations

The dopamine D2 receptor: two molecular forms generated by alternative splicing.

1989 • 596 citations

Neuro‐Psychopharmacology

1962 • 595 citations

Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation.

1992 • 587 citations

Cloning and expression of human and rat Dt dopamine receptors

1990 • 566 citations

D1 and D2 dopamine receptor gene expression in the rat striatum: Sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAS in distinct neuronal populations of the dorsal and ventral striatum

1995 • 566 citations

Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons

1995 • 542 citations

Conserved aspartic acid residues 79 and 113 of the beta-adrenergic receptor have different roles in receptor function.

1988 • 533 citations

Identification of Two Serine Residues Involved in Agonist Activation of the β-Adrenergic Receptor

1989 • 522 citations

Molecular Diversity of the Dopamine Receptors

1993 • 506 citations

Effects of Dopamine in Man: Augmentation of Sodium Excretion, Glomerular Filtration Rate, and Renal Plasma Flow*

1964 • 505 citations

Localization of dopamine D4 receptors in GABAergic neurons of the primate brain

1996 • 494 citations

Opposite Modulation of Cocaine-Seeking Behavior by D ₁ - and D ₂ -Like Dopamine Receptor Agonists

1996 • 493 citations

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

1994 • 490 citations

Dopamine receptors: Molecular biology, biochemistry and behavioural aspects

1994 • 489 citations

Cloning of the cDNA and gene for a human D2 dopamine receptor.

1989 • 488 citations

Regional, cellular, and subcellular variations in the distribution of D1 and D5 dopamine receptors in primate brain

1995 • 486 citations

D1 and D2 dopamine receptor mRNA in rat brain.

1991 • 483 citations

Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents

1995 • 483 citations

Neuroleptics increase C-FOS expression in the forebrain: Contrasting effects of haloperidol and clozapine

1992 • 477 citations

Phenotypical characterization of the rat striatal neurons expressing the D1 dopamine receptor gene.

1991 • 477 citations

Dopamine receptor gene expression by enkephalin neurons in rat forebrain.

1990 • 469 citations

Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine.

1992 • 466 citations

Molecular cloning and expression of a D1 dopamine receptor linked to adenylyl cyclase activation.

1990 • 458 citations

Modulation of Cocaine Self-Administration in the Rat Through D-3 Dopamine Receptors

1993 • 452 citations

Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2 receptors, clozapine occupies D4.

1992 • 445 citations

Dopamine receptor subtypes colocalize in rat striatonigral neurons.

1992 • 428 citations

Comparative systemic and regional hemodynamic effects of dopamine and dobutamine in patients with cardiomyopathic heart failure.

1978 • 426 citations

The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP.

1989 • 423 citations

Modeling of G-protein-coupled receptors: application to dopamine, adrenaline, serotonin, acetylcholine, and mammalian opsin receptors

1992 • 415 citations

The Mechanism of Action of Novel Antipsychotic Drugs

1991 • 410 citations

Two adjacent cysteine residues in the C‐terminal cytoplasmic fragment of bovine rhodopsin are palmitylated

1988 • 409 citations

Dissociation of hippocampus and caudate nucleus memory systems by posttraining intracerebral injection of dopamine agonists.

1991 • 396 citations

D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines.

1994 • 384 citations

Dopaminergic receptors in the anterior pituitary gland. Correlation of [3H]dihydroergocryptine binding with the dopaminergic control of prolactin release.

1978 • 376 citations

Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor.

1991 • 359 citations

Localization of D1 dopamine receptor mRNA in brain supports a role in cognitive, affective, and neuroendocrine aspects of dopaminergic neurotransmission.

1991 • 354 citations

Phenotypical characterization of neurons expressing the dopamine D3 receptor in the rat brain

1995 • 351 citations

Altered striatal function in a mutant mouse lacking D1A dopamine receptors.

1994 • 350 citations

A Comparison of the Vascular Dopamine Receptor with Other Dopamine Receptors

1978 • 335 citations

Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

1994 • 334 citations

Differential expression of c-fos and zif268 in rat striatum after haloperidol, clozapine, and amphetamine.

1992 • 334 citations

Reciprocal Influence of Salt Intake on Adrenal Glomerulosa and Renal Vascular Responses to Angiotensin II in Normal Man

1974 • 333 citations

D1 and D2 dopamine receptors differentially regulate c-fos expression in striatonigral and striatopallidal neurons

1992 • 331 citations

Dissociation of hippocampus and caudate nucleus memory systems by posttraining intracerebral injection of dopamine agonists.

1991 • 330 citations

Three-dimensional models of neurotransmitter G-binding protein-coupled receptors.

1991 • 330 citations

Behavioral studies following lesions of the mesolimbic and mesostriatal serotonergic pathways

1976 • 311 citations

Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme.

1991 • 307 citations

D1-like and D2-like dopamine receptors synergistically activate rotation and c-fos expression in the dopamine-depleted striatum in a rat model of Parkinson's disease

1992 • 300 citations

Novel dopamine receptors half a decade later

1995 • 296 citations

Dopamine receptor subtypes: beyond the D1/D2 classification

1990 • 295 citations

Inhibition by dopamine of (Na+ + K+)ATPase activity in neostriatal neurons through D1 and D2 dopamine receptor synergism

1990 • 286 citations

Effects of Dietary Sodium and of Acute Saline Infusion on the Interrelationship between Dopamine Excretion and Adrenergic Activity in Man

1974 • 277 citations

Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas

1979 • 271 citations

An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium.

1990 • 266 citations

Distribution of D2 dopamine receptor mRNA in rat brain.

1989 • 263 citations

Resistance to Bromocriptine in Prolactinomas

1989 • 263 citations

Dopamine activation of the arachidonic acid cascade as a basis for D1D2 receptor synergism

1991 • 262 citations

High agonist-independent activity is a distinguishing feature of the dopamine D1B receptor subtype.

1994 • 261 citations

Studies on the pharmacological properties of dopamine receptors in various areas of the central nervous system.

1978 • 260 citations

The dopamine D3-receptor: A postsynaptic receptor inhibitory on rat locomotor activity

1993 • 259 citations

Dopamine D2 receptor mechanisms contribute to age-related cognitive decline: the effects of quinpirole on memory and motor performance in monkeys

1995 • 259 citations

Immunohistochemical localization of the D1 dopamine receptor in rat brain reveals its axonal transport, pre- and postsynaptic localization, and prevalence in the basal ganglia, limbic system, and thalamic reticular nucleus.

1992 • 258 citations

G(olf) and Gs in rat basal ganglia: possible involvement of G(olf) in the coupling of dopamine D1 receptor with adenylyl cyclase

1993 • 255 citations

Pharmacological characterization of the D2 dopamine receptor negatively coupled with adenylate cyclase in rat anterior pituitary.

1983 • 254 citations

Mechanisms of action of atypical antipsychotic drugs

1991 • 254 citations

Activation of heterologously expressed D3 dopamine receptors: comparison with D2 dopamine receptors.

1994 • 253 citations

Dopamine and the Kidney

1982 • 246 citations

Regionally specific effects of atypical antipsychotic drugs on striatal Fos expression: The nucleus accumbens shell as a locus of antipsychotic action

1992 • 238 citations

Characterization of dopamine receptors mediating inhibition of adenylate cyclase activity in rat striatum.

1985 • 236 citations

Differential coupling of dopaminergic D2 receptors expressed in different cell types. Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in LtK- fibroblasts, hyperpolarization, and cytosolic-free Ca2+ concentration decrease in GH4C1 cells.

1990 • 235 citations

Direct Renal Vasodilatation Produced by Dopamine in the Dog

1965 • 233 citations

Effects of Metoclopramide and Bromocriptine on the Renin-Angiotensin-Aldosterone System in Man

1979 • 222 citations

Site-directed mutagenesis of alpha 2A-adrenergic receptors: identification of amino acids involved in ligand binding and receptor activation by agonists.

1991 • 221 citations

Expression of the d3 dopamine receptor in peptidergic neurons of the nucleus accumbens: Comparison with the D1 and D2 dopamine receptors

1996 • 220 citations

Activation of facilitation calcium channels in chromaffin cells by D1 dopamine receptors through a cAMP/protein kinase A-dependent mechanism

1990 • 218 citations

Expression and pharmacological characterization of the human D3 dopamine receptor.

1994 • 218 citations

Stimulation of a dopamine D1 receptor enhances inositol phosphates formation in rat brain.

1990 • 217 citations

Differential G protein-mediated coupling of D2 dopamine receptors to K+ and Ca2+ currents in rat anterior pituitary cells

1992 • 216 citations

Role of extracellular disulfide-bonded cysteines in the ligand binding function of the .beta.2-adrenergic receptor

1990 • 215 citations

Multiple human D5 dopamine receptor genes: a functional receptor and two pseudogenes.

1991 • 210 citations

Expression of striatal D1 dopamine receptors coupled to inositol phosphate production and Ca2+ mobilization in Xenopus oocytes.

1990 • 208 citations

Anterior pituitary development: Short tales from dwarf mice

1992 • 208 citations

Drugs acting on brain dopamine receptors: A conceptual re-evaluation five years after the first selective D-1 antagonist

1989 • 207 citations

Unique binding characteristics of antipsychotic agents interacting with human dopamine D2A, D2B, and D3 receptors.

1993 • 207 citations

Dopamine receptors: applications in clinical cardiology.

1985 • 206 citations

Dopamine inhibits Na(+)-H+ exchanger activity in renal BBMV by stimulation of adenylate cyclase

1990 • 206 citations

The rat dopamine D4 receptor: sequence, gene structure, and demonstration of expression in the cardiovascular system.

1992 • 204 citations

6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.

1987 • 201 citations

Photoreceptors of mouse retinas possess D4 receptors coupled to adenylate cyclase.

1992 • 200 citations

Pharmacological and functional characterization of D2, D3 and D4 dopamine receptors in fibroblast and dopaminergic cell lines.

1994 • 197 citations

Mammalian Na+/H+ exchanger gene family: structure and function studies

1995 • 196 citations

Dopamine D3 receptor mRNA and binding sites in human brain

1993 • 193 citations

The renal dopamine receptors.

1992 • 192 citations

The D2 dopamine receptor isoforms signal through distinct Gi alpha proteins to inhibit adenylyl cyclase. A study with site-directed mutant Gi alpha proteins.

1994 • 191 citations

Behavioral correlations of dopamine receptor activation

1983 • 188 citations

Evidence for a Distinct D₁Like Dopamine Receptor that Couples to Activation of Phosphoinositide Metabolism in Brain

1994 • 187 citations

Pivotal role for aspartate-80 in the regulation of dopamine D2 receptor affinity for drugs and inhibition of adenylyl cyclase.

1991 • 185 citations

Striatal Fos expression is indicative of dopamine D1/D2 synergism and receptor supersensitivity.

1993 • 185 citations

Dopaminergic Inhibition of Metoclopramide-induced Aldosterone Secretion in Man

1980 • 183 citations

Behavioural effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other “D-2-like” agonists

1993 • 183 citations

A paradoxical regulation of the dopamine D3 receptor expression suggests the involvement of an anterograde factor from dopamine neurons.

1995 • 183 citations

Sodium Diuresis Produced by Dopamine in Patients with Congestive Heart Failure

1963 • 180 citations

Role of D1 and D2 dopamine receptors in mediating locomotor activity elicited from the nucleus accumbens of rats

1989 • 178 citations

The dopamine-1 agonist, SKF 82526, stimulates phospholipase-C activity independent of adenylate cyclase.

1989 • 177 citations

The nature of the trophic action of brain-derived neurotrophic factor, des(1-3)-insulin-like growth FACTOR-1, and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture

1993 • 176 citations

Differential Visualization of Dopamine D2 and D3 Receptor Sites in Rat Brain. A Comparative Study Using In Situ Hybridization Histochemistry and Ligand Binding Autoradiography

1993 • 176 citations

Distribution of D5 dopamine receptor mRNA in rat brain

1992 • 176 citations

Alternative Splicing of the Dopamine D2 Receptor Directs Specificity of Coupling to G-proteins

1995 • 172 citations

D1 and D2 dopamine receptors differentially increase fos-like immunoreactivity in accumbal projections to the ventral pallidum and midbrain

1995 • 170 citations

Site-directed mutagenesis of the human dopamine D2 receptor

1992 • 165 citations

Structure/function studies of mammalian Na‐H exchangers‐‐an update.

1995 • 162 citations

The Dopamine Receptor in the Intermediate Lobe of the Rat Pituitary Gland: Pharmacological Characterization

1980 • 159 citations

Site-directed mutagenesis and continuous expression of human beta-adrenergic receptors. Identification of a conserved aspartate residue involved in agonist binding and receptor activation.

1988 • 158 citations

D1 dopamine receptors in the nucleus accumbens modulate cocaine self-administration in the rat

1993 • 157 citations

Beyond the Dopamine Hypothesis

1989 • 155 citations

Site-directed Mutagenesis of β-Adrenergic Receptors

1989 • 155 citations

Dopamine receptor interactions: some implications for the treatment of Parkinson's disease

1992 • 154 citations

Evidence for the coupling of Gq protein to D1-like dopamine sites in rat striatum: possible role in dopamine-mediated inositol phosphate formation.

1995 • 150 citations

Dopamine receptor mRNA expression patterns by opioid peptide cells in the nucleus accumbens of the rat: A double in situ hybridization study

1995 • 150 citations

Coupling of a cloned rat dopamine-D2 receptor to inhibition of adenylyl cyclase and prolactin secretion.

1990 • 149 citations

Dopamine D2 and D3 receptors inhibit dopamine release.

1994 • 149 citations

Tonic Dopaminergic Suppression of Plasma Aldosterone*

1980 • 148 citations

G protein specificity in receptor-effector coupling. Analysis of the roles of G0 and Gi2 in GH4C1 pituitary cells.

1994 • 146 citations

Histofluorescence Techniques Provide Evidence for Dopamine-Containing Neuronal Elements in Canine Kidney

1979 • 146 citations

Defective dopamine-1 receptor adenylate cyclase coupling in the proximal convoluted tubule from the spontaneously hypertensive rat.

1989 • 144 citations

Inhibition of proximal tubule Na(+)-K(+)-ATPase activity requires simultaneous activation of DA1 and DA2 receptors

1990 • 142 citations

Full-length cDNA cloning and distribution of human dopamine D4 receptor

1995 • 141 citations

Behavioral and neurochemical data suggest functional differences between dopamine D2 and D3 receptors

1994 • 140 citations

Proximal tubule Na+-K+-ATPase activity is inhibited during high-salt diet: evidence for DA-mediated effect

1988 • 139 citations

Partial and full dopamine D1 receptor agonists in mice and rats: relation between behavioural effects and stimulation of adenylate cyclase activity in vitro

1992 • 138 citations

Shorter variants of the D3 dopamine receptor produced through various patterns of alternative splicing

1991 • 138 citations

Structures of Dopamine Receptors

1993 • 137 citations

The dopamine receptor in adult and maturing kidney

1989 • 137 citations

Na+-K+-ATPase is an effector protein for protein kinase C in renal proximal tubule cells

1989 • 134 citations

Preferential coupling between dopamine D2 receptors and G-proteins.

1993 • 132 citations

Biochemical and Physiological Studies of the Beta-Adrenoceptor and the D-2 Dopamine Receptor in the Intermediate Lobe of the Rat Pituitary Gland: A Review

1982 • 125 citations

Molecular cloning and characterization of a high affinity dopamine receptor (D1 beta) and its pseudogene.

1991 • 125 citations

Dopaminergic inhibition of adenylate cyclase correlates with high affinity agonist binding to anterior pituitary D2 dopamine receptors

1984 • 125 citations

Dopamine regulation of renal Na+,K(+)-ATPase activity is lacking in Dahl salt-sensitive rats.

1993 • 125 citations

Prostaglandin E2 inhibits sodium transport in rabbit cortical collecting duct by increasing intracellular calcium.

1991 • 125 citations

Transfected D2 dopamine receptors mediate the potentiation of arachidonic acid release in Chinese hamster ovary cells.

1991 • 124 citations

Contributions of Conserved Serine Residues to the Interactions of Ligands with Dopamine D2 Receptors

1992 • 123 citations

Dopamine-1-mediated Stimulation of Phospholipase C Activity in Rat Renal Cortical Membranes

1989 • 122 citations

D1–D2 dopamine receptor synergy in striatum: effects of intrastriatal infusions of dopamine agonists and antagonists on immediate early gene expression

1995 • 121 citations

Functional coupling of the human dopamine D3 receptor in a transfected NG 108-15 neuroblastoma-glioma hybrid cell line

1994 • 121 citations

No Linkage Between D2 Dopamine Receptor Gene Region and Schizophrenia

1991 • 121 citations

Striatal c-fos Induction by Cocaine or Apomorphine Occurs Preferentially in Output Neurons Projecting to the Substantia Nigra in the Rat

1992 • 120 citations

Dopaminergic modulation of adenylate cyclase stimulation by vasoactive intestinal peptide in anterior pituitary.

1981 • 118 citations

Intracellular signaling in the regulation of renal Na-K-ATPase. II. Role of eicosanoids.

1993 • 118 citations

Dopamine decreases fluid reabsorption in straight portions of rabbit proximal tubule

1982 • 118 citations

Characterization of the human dopamine D3 receptor expressed in transfected cell lines

1994 • 117 citations

D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells.

1994 • 115 citations

Dopamine Inhibits Two Characterized Voltage-Dependent Calcium Currents in Identified Rat Lactotroph Cells

1990 • 115 citations

A Family of POU-Domain and Pit-1 Tissue-Specific Transcription Factors in Pituitary and Neuroendocrine Development

1990 • 115 citations

Intracellular signaling in the regulation of renal Na-K-ATPase. I. Role of cyclic AMP and phospholipase A2.

1992 • 114 citations

DOPAMINE‐CONTAINING VASOMOTOR NERVES IN THE DOG KIDNEY

1978 • 114 citations

Transcription mediated by a cAMP-responsive promoter element is reduced upon activation of dopamine D2 receptors.

1991 • 114 citations

Inhibitory control of prolactin and Pit-1 gene promoters by dopamine. Dual signaling pathways required for D2 receptor-regulated expression of the prolactin gene.

1991 • 113 citations

Bilateral intra-accumbens self-administration ofd-amphetamine: Antagonism with intra-accumbens SCH-23390 and sulpiride

1994 • 113 citations

Colocalization of D1 and D2 dopamine receptor mRNAs in striatal neurons

1993 • 113 citations

Dopamine fails to inhibit renal tubular sodium pump in hypertensive rats.

1993 • 112 citations

Immediate-early genes, neuronal plasticity, and memory

1992 • 110 citations

Protein kinase C-dependent and -independent activation of Na+/H+ exchanger by G alpha 12 class of G proteins.

1994 • 109 citations

Acute and chronic amphetamine treatments differently regulate neuropeptide messenger RNA levels and Fos immunoreactivity in rat striatal neurons

1995 • 109 citations

Metabolic Substrates, Cellular Energy Production, and the Regulation of Proximal Tubular Transport

1985 • 108 citations

Attenuated renal response to dopaminergic drugs in spontaneously hypertensive rats.

1990 • 108 citations

The Dopamine D1D Receptor

1995 • 107 citations

Receptor subtype-specific dopaminergic agents and conditioned behavior

1989 • 106 citations

Relationship between the Adrenergic Nervous System and Renin during Adaptation to Upright Posture: A Possible Role for 3,4-Dihydroxyphenethylamine (Dopamine)

1972 • 106 citations

Dopaminergic Control of Plasma Catecholamine and Aldosterone Responses to Acute Stimuli in Normal Man

1980 • 106 citations

Comparison of the Effects of the Neurotrophins on the Morphological Structure of Dopaminergic Neurons in Cultures of Rat Substantia Nigra

1995 • 106 citations

A novel short isoform of the D3 dopamine receptor generated by alternative splicing in the third cytoplasmic loop.

1993 • 104 citations

Hormonal interactions with the proximal Na(+)-H+ exchanger

1990 • 103 citations

Role of kidney dopamine in the natriuretic response to volume expansion in rats.

1989 • 103 citations

Cholinergic and dopaminergic modulation of potassium conductances in neostriatal neurons.

1993 • 103 citations

Opposing Roles for Dopamine D₂ and D₃ Receptors on Neurotensin mRNA Expression in Nucleus Accumbens

1994 • 102 citations

Localization of multiple dopamine receptor subtype mRNAs in human and monkey motor cortex and striatum

1992 • 100 citations

Dopamine and the pharmacology of schizophrenia: The state of the evidence

1974 • 99 citations

Dopamine induces neurite retraction in retinal horizontal cells via diacylglycerol and protein kinase C.

1990 • 99 citations

Linkage analysis of schizophrenia with five dopamine receptor genes in nine pedigrees.

1993 • 98 citations

Plasma and Urine Dopamine in Man Given Sodium Chloride in the Diet

1979 • 98 citations

Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells.

1989 • 97 citations

This is not a G protein-coupled receptor

1993 • 97 citations

Cortical tubular and glomerular dopamine receptors in the rat kidney

1984 • 96 citations

Different mechanisms of renal Na-K-ATPase regulation by protein kinases in proximal and distal nephron

1993 • 95 citations

The D-1 Dopamine Receptor and the Search for its Functional Role: From Neurochemistry to Behaviour

1987 • 95 citations

Inhibition of inositol phospholipid breakdown by D2 dopamine receptors in dissociated bovine anterior pituitary cells

1985 • 95 citations

Dopamine receptor subtypes in renal brush border and basolateral membranes

1989 • 95 citations

Electrophysiological responses to dopamine of rat hypophysial cells in lactotroph‐enriched primary cultures.

1987 • 94 citations

Epidermal growth factor exerts neuronotrophic effects on dopaminergic and GABAergic CNS neurons: Comparison with basic fibroblast growth factor

1991 • 94 citations

Dopaminergic inhibition of DNA synthesis in pituitary tumor cells is associated with phosphotyrosine phosphatase activity.

1992 • 93 citations

Localized intracaudate dopamine D2 receptor activation during the post-training period improves memory for visual or olfactory conditioned emotional responses in rats

1991 • 92 citations

Nerve growth factor suppresses the transforming phenotype of human prolactinomas.

1993 • 92 citations

The Inhibition of Phosphatidylinositol Turnover: A Possible Postreceptor Mechanism for the Prolactin Secretion-Inhibiting Effect of Dopamine^*

1983 • 88 citations

Morphogenic potentials of D2, D3, and D4 dopamine receptors revealed in transfected neuronal cell lines.

1994 • 88 citations

Dopamine actions on calcium currents, potassium currents and hormone release in rat melanotrophs.

1991 • 87 citations

D2 dopamine receptor activation of potassium channels in identified rat lactotrophs: whole-cell and single-channel recording

1991 • 87 citations

The effect of dopamine receptor blockade on natriuresis is dependent on the degree of hypervolemia

1991 • 86 citations

Functional expression and characterization of human D2 and D3 dopamine receptors

1994 • 86 citations

Localization of dopamine D1A receptor protein in rat kidneys

1995 • 85 citations

Dopamine-modulated potassium channels on rat striatal neurons: specific activation and cellular expression

1995 • 85 citations

The D2S and D2L dopamine receptor isoforms are differentially regulated in Chinese hamster ovary cells.

1994 • 85 citations

Reward and detection thresholds for brain stimulation: dissociative effects of cocaine

1981 • 85 citations

An evolutionary view of drug-receptor interaction: the bioamine receptor family

1995 • 85 citations

Management of prolactinomas

1991 • 85 citations

A transduction pathway associated with receptors coupled to the inhibitory guanine nucleotide binding protein Gi that amplifies ATP-mediated arachidonic acid release.

1991 • 84 citations

Coupling of Human D-1 Dopamine Receptors to Different Guanine Nucleotide Binding Proteins. EVIDENCE THAT D-1 DOPAMINE RECEPTORS CAN COUPLE TO BOTH Gs AND Go

1995 • 83 citations

Response of isolated renal arterioles to acetylcholine, dopamine, and bradykinin

1985 • 83 citations

Decreased Plasma and Urinary Dopamine during Dietary Sodium Depletion in Man*

1981 • 81 citations

Effects of dopamine on renal function and hemodynamics in the dog.

1967 • 80 citations

Receptor Subtypes in Opioid and Stimulant Reward

1992 • 80 citations

Selective peripheral dopamine-1 receptor stimulation with fenoldopam in human essential hypertension.

1984 • 80 citations

Reward and Abuse of Opiates

1992 • 79 citations

Differential Sensitivity of the Short and Long Human Dopamine D₂ Receptor Subtypes to Protein Kinase C

1992 • 79 citations

Changes in dopamine D1, D2 and D3 receptor mRNA levels in rat brain following antipsychotic treatment

1992 • 78 citations

Dopaminergic Modulation of Aldosterone Secretion in Man is Unaffected by Glucocorticoids and Angiotensin Blockade

1981 • 78 citations

Striatal neurons express increased level of dopamine D2 receptor mRNA in response to haloperidol treatment: A quantitative in situ hybridization study

1991 • 77 citations

Differences in the Ligand Binding Properties of the Short and Long Versions of the D₂Dopamine Receptor

1993 • 77 citations

Defective G protein activation of the cAMP pathway in rat kidney during genetic hypertension.

1995 • 73 citations

Blockade of renal effects of dopamine in the dog by the DA1 antagonist SCH 23390

1985 • 73 citations

Neurochemical Evidence that Postsynaptic Nucleus Accumbens D₃ Receptor Stimulation Enhances Cocaine Reinforcement

1996 • 73 citations

Epidermal Growth Factor and Basic Fibroblast Growth Factor Protect Dopaminergic Neurons from Glutamate Toxicity in Culture

1995 • 71 citations

Sulpiride and Haloperidol in Schizophrenia: A Double-blind Cross-over Study of Therapeutic Effect, Side Effects and Plasma Concentrations

1985 • 71 citations

Hormone responses of proximal Na(+)-H+ exchanger in spontaneously hypertensive rats

1991 • 70 citations

Adenosinergic modulation of caffeine-induced c-fos mRNA expression in mouse brain

1989 • 70 citations

Cloning and characterization of the opossum kidney cell D1 dopamine receptor: expression of identical D1A and D1B dopamine receptor mRNAs in opossum kidney and brain.

1993 • 70 citations

Dopamine D1A Receptor Regulation of Phospholipase C Isoform

1996 • 69 citations

Dopaminergic Inhibition of Prolactin Release and Calcium Influx Induced by Neurotensin in Anterior Pituitary Is Independent of Cyclic AMP System

1986 • 69 citations

Distribution of dopamine D1, D2, and D5 receptor mRNAs in the monkey brain: ribonuclease protection assay analysis

1995 • 69 citations

Analysis of the D4 Dopamine Receptor Gene Variant in an Italian Schizophrenia Kindred

1994 • 69 citations

Differential effects of dopamine D2 and D3 receptor antagonists in regard to dopamine release, in vivo receptor displacement and behaviour

1994 • 69 citations

Dopamine inhibits Na/K-ATPase in single tubules and cultured cells from distal nephron

1992 • 68 citations

Evidence from functional and autoradiographic studies for the presence of tubular dopamine-1 receptors and their involvement in the renal effects of fenoldopam.

1989 • 68 citations

Dopamine D2 receptor stimulation of Na+/H+ exchange assessed by quantification of extracellular acidification.

1992 • 67 citations

Excretion of Phosphate and Calcium

1973 • 67 citations

Dopaminergic modulation of salt sensitivity in patients with essential hypertension

1986 • 67 citations

Multiple receptors coupled to adenylate cyclase regulate Na-H exchange independent of cAMP.

1990 • 66 citations

Potassium Channel Blockers Inhibit D₂ Dopamine, but Not A₁Adenosine, Receptor‐Mediated Inhibition of Striatal Dopamine Release

1991 • 66 citations

Phosphaturic effect of dopamine in dogs. Possible role of intrarenally produced dopamine in phosphate regulation.

1976 • 66 citations

Expression of dopamine D2 receptor and choline acetyltransferase mRNA in the dopamine deafferented rat caudate-putamen

1990 • 66 citations

Functional interactions between D-1 and D-2 dopamine receptor systems: their role in the regulation of psychomotor behaviour, putative mechanisms, and clinical relevance

1989 • 65 citations

Acute Dopaminergic Inhibition of Aldosterone Secretion Is Independent of Angiotensin II and Adrenocorticotropin*

1982 • 65 citations

Different expression of the two dopaminergic D2 receptors, D2₄₁₅and D2₄₄₄, in two types of lactotroph each characterised by their response to dopamine, and modification of expression by sex steroids.

1991 • 64 citations

Synaptic modulation by dopamine of calcium currents in rat pars intermedia

1990 • 64 citations

D1A, D1B, and D1C dopamine receptors from Xenopus laevis.

1994 • 64 citations

Exclusion of Linkage Between Schizophrenia and the D2 Dopamine Receptor Gene Region of Chromosome 11q in 112 Irish Multiplex Families

1993 • 64 citations

Alternative transcripts of the rat and human dopamine D3 receptor

1991 • 63 citations

Functional expression of human D₃ dopamine receptors in differentiated neuroblastoma × glioma NG108–15 cells

1994 • 63 citations

Epidermal Growth Factor Induces the Functional Expression of Dopamine Receptors in the GH3 Cell Line*

1991 • 63 citations

D2 dopamine receptor localization on striatonigral neurons

1992 • 62 citations

Memory enhancement by post-training peripheral administration of low doses of dopamine agonists: Possible autoreceptor effect

1993 • 62 citations

D2 dopamine receptor stimulation of mitogenesis in transfected Chinese hamster ovary cells: relationship to dopamine stimulation of tyrosine phosphorylations.

1993 • 62 citations

Nonlinkage of bipolar illness to tyrosine hydroxylase, tyrosinase, and D2 and D4 dopamine receptor genes on chromosome 11

1994 • 62 citations

Heterogeneous distribution of D1, D2 and D5 receptor mRNAs in monkey striatum

1993 • 62 citations

Cholera toxin-sensitive 3',5'-cyclic adenosine monophosphate and calcium signals of the human dopamine-D1 receptor: selective potentiation by protein kinase A.

1992 • 61 citations

Further evidence of no linkage between schizophrenia and the dopamine D₃ receptor gene locus

1994 • 61 citations

Methamphetamine-induced changes in the striatal-nigral dynorphin system: role of D-1 and D-2 receptors

1987 • 61 citations

Potassium channels involved in the transduction mechanism of dopamine D2 receptors in rat lactotrophs.

1989 • 61 citations

Effects of Dopamine on Voltage-Dependent Potassium Currents in Identified Rat Lactotroph Cells

1990 • 61 citations

Acute and Chronic Nicotinic Interactions with Dopamine Systems and Working Memory Performance^a

1995 • 60 citations

Derivation of urinary dopamine from plasma dopa

1988 • 60 citations

Source and Handling of Renal Dopamine: Its Physiological Importance

1994 • 60 citations

Modulation of mesolimbic dopamine release by the selective dopamine D3 receptor antagonist, (+)-S 14297

1994 • 59 citations

High-affinity uptake of 67Cu into a veratridine-releasable pool in brain tissue

1989 • 59 citations

Anatomical study of enkephalin gene expression in the rat forebrain following haloperidol treatment

1987 • 58 citations

Response of striatonigral substance P systems to a dopamine receptor agonist and antagonist

1981 • 58 citations

Dopaminergic mediation of the natriuretic response to volume expansion.

1985 • 57 citations

Renal tubular reabsorption of sodium and water during infusion of low-dose dopamine in normal man

1990 • 57 citations

Expression of the D2 subfamily of dopamine receptor genes in kidney

1994 • 56 citations

Dopaminergic Modulation of Aldosterone Secretion Is Independent of Alterations in Renin Secretion*

1980 • 56 citations

Grooming and vacuous chewing induced by SK&F 83959, and agonist of dopamine ‘D1-like’ receptors that inhibits dopamine-sensitive adenylyl cyclase

1993 • 56 citations

A dopaminergic inhibitory postsynaptic potential mediated by an increased potassium conductance

1989 • 55 citations

Urinary Dopamine Excretion in Normotensive Subjects wiht or without Family History of Hypertension

1986 • 55 citations

Role of the Nucleus Accumbens and the Striatum in the Production of Turning Behaviour in Intact Rats

1994 • 55 citations

Characterization of subtype-specific antibodies to the human D5 dopamine receptor: studies in primate brain and transfected mammalian cells.

1995 • 54 citations

Effects of Dopaminergic Transmission Interruption on the D₂ Receptor Isoforms in Various Cerebral Tissues

1992 • 54 citations

Towards More Effective Antipsychotic Treatment

1994 • 54 citations

Organ specificity of the dopamine1 receptor/adenylyl cyclase coupling defect in spontaneously hypertensive rats

1993 • 54 citations

Genetic Transmission

1993 • 54 citations

Inhibition of Na+, K+-ATPase in rat renal proximal tubules by dopamine involved DA-1 receptor activation

1993 • 53 citations

Expression of dopamine D1A receptor gene in proximal tubule of rat kidneys

1993 • 51 citations

Pharmacology of high‐threshold calcium currents in GH₄C₁ pituitary cells and their regulation by activation of human D₂ and D₄ dopamine receptors

1994 • 50 citations

Induction of classical lactotropes by epidermal growth factor in rat pituitary cell cultures.

1995 • 50 citations

Endogenous Dopamine (DA) and DA2 Receptors: A Mechanism Limiting Excessive Sympathetic-Adrenal Discharge in Humans*

1988 • 50 citations

A Paradoxical Fall in Urine Dopamine Output When Patients with Essential Hypertension Are Given Added Dietary Salt

1984 • 49 citations

Dopamine D1 receptor family agonists, SK&F38393, SK&F77434, and SK&F82958, Differentially affect locomotor activities in rats

1993 • 49 citations

Opposing Actions of D1 and D2-Dopamine Receptors on Arachidonic Acid Release and Cyclic AMP Production in Striatal Neurons

1994 • 49 citations

Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype.

1994 • 48 citations

Rat Juxtaglomerular Cells are Endowed with DA-1 Dopamine Receptors Mediating Renin Release

1988 • 48 citations

Diminished phospholipase C activation by dopamine in spontaneously hypertensive rats.

1992 • 48 citations

Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C

1993 • 48 citations

Dopamine DA2-receptor activation inhibits noradrenaline release in human kidney slices

1993 • 47 citations

Identification and Characterization of Postsynaptic D1- and D2-Dopamine Receptors in the Cardiovascular System

1988 • 47 citations

Na-K-ATPase in nephron segments of rats developing spontaneous hypertension

1985 • 47 citations

Exclusion of close linkage of Tourette's syndrome to D1 dopamine receptor

1993 • 46 citations

Quantitative in situ hybridization evidence for differential regulation of proenkephalin and dopamine D2 receptor mRNA levels in the rat striatum: effects of unilateral intrastriatal injections of 6-hydroxydopamine

1992 • 46 citations

Dopaminergic mediation of the diuretic and natriuretic effects of ANF in the rat

1986 • 46 citations

Dopaminergic inhibition of the action of vasopressin on the cortical collecting tubule

1985 • 46 citations

Dual mechanisms of inhibition by dopamine of basal and thyrotropin-releasing hormone-stimulated inositol phosphate production in anterior pituitary cells. Evidence for an inhibition not mediated by voltage-dependent Ca2+ channels.

1990 • 46 citations

Differential influence of haloperidol and sulpiride on dopamine receptors and peptide mRNA levels in the rat striatum and pituitary

1994 • 45 citations

D2 dopamine receptors modulate calcium channel currents and catecholamine secretion in bovine adrenal chromaffin cells.

1990 • 45 citations

Differential Coupling of D1 and D5 Dopamine Receptors to Guanine Nucleotide Binding Proteins in Transfected GH4C1 Rat Somatomammotrophic Cells

1995 • 45 citations

Cloning and characterization of a truncated dopamine D1 receptor from goldfish retina: stimulation of cyclic AMP production and calcium mobilization.

1993 • 45 citations

Characterization of cloned human dopamine D1 receptor-mediated calcium release in 293 cells.

1995 • 45 citations

Behavioural evidence for “D-1-like” dopamine receptor subtypes in rat brain using the new isochroman agonist A 68930 and isoquinoline antagonist BW 737C

1993 • 44 citations

D1A dopamine receptor stimulation inhibits Na+/K(+)-ATPase activity through protein kinase A.

1993 • 44 citations

D₁ Dopamine Receptors Can Interact with Both Stimulatory and Inhibitory Guanine Nucleotide Binding Proteins

1991 • 44 citations

Dialysis of lactotropes with antisense oligonucleotides assigns guanine nucleotide binding protein subtypes to their channel effectors.

1992 • 43 citations

K+ channel and adenylate cyclase involvement in regulation of Ca2+-evoked release of [3H]dopamine from synaptosomes.

1989 • 43 citations

Dopamine Receptors on Adrenal Chromaffin Cells Modulate Calcium Uptake and Catecholamine Release

1988 • 43 citations

Dopamine D1 Receptor Mutagenesis: Role of Amino Acids in Agonist and Antagonist Binding

1993 • 43 citations

Chimeric D₂/D₃ Dopamine Receptors Efficiently Inhibit Adenylyl Cyclase in HEK 293 Cells

1996 • 43 citations

Dopamine neuron membrane physiology: Characterization of the transient outward current (I_A) and demonstration of a common signal transduction pathway for I_A and I_K

1994 • 43 citations

Epidermal Growth Factor and Basic Fibroblast Growth Factor Have Independent Actions on Mesencephalic Dopamine Neurons in Culture

1994 • 42 citations

Functional Coupling of Human D₂, D₃, and D₄ Dopamine Receptors in HEK293 Cells

1995 • 42 citations

Intrarenally produced angiotensin II opposes the natriuretic action of the dopamine-1 receptor agonist fenoldopam in rats.

1991 • 41 citations

Endogenous renal dopamine production regulates phosphate excretion

1994 • 41 citations

Characterization of Dopamine Receptors Associated with Aldosterone Secretion in Rat Adrenal Glomerulosa*

1986 • 40 citations

Autoradiographic Localization of Vascular Dopamine Receptors

1990 • 40 citations

Characteristics of stably expressed human dopamine D1a and D1b receptors: Atypical behavior of the dopamine D1b receptor

1994 • 39 citations

Characterization of a dopamine receptor (DA2K) in the kidney inner medulla.

1991 • 39 citations

Dopaminergic suppression of angiotensin II-induced aldosterone secretion in man: Differential responses during sodium loading and depletion

1984 • 39 citations

Role of dopaminergic mechanisms in the kidney for the pathogenesis of hypertension

1990 • 39 citations

Dopaminergic Receptor Mechanisms Modulating the Renin-Angiotensin System and Aldosterone Secretion

1989 • 38 citations

Persistent defective coupling of dopamine-1 receptors to G proteins after solubilization from kidney proximal tubules of hypertensive rats.

1992 • 38 citations

Evidence that specific dopamine-1 receptor activation is involved in dopamine-induced renin release.

1989 • 38 citations

Effects of Different Dopaminergic Antagonists on Bromocriptine-Induced Inhibition of Norepinephrine Release*

1984 • 37 citations

Autoradiographic localization of dopamine DA1 receptors in rat kidney with [3H]Sch 23390

1989 • 37 citations

Neural not tubular dopamine increases glomerular filtration rate in perfused rat kidneys

1986 • 37 citations

Increased Urinary Dopamine Excretion in Young Patients with Essential Hypertension

1994 • 36 citations

The D2 dopamine receptor mediates inhibition of growth in GH4ZR7 cells: involvement of protein kinase-C epsilon.

1994 • 36 citations

Depression of high‐threshold calcium currents by activation of human D₂ (short) dopamine receptors expressed in differentiated NG108‐15 cells

1994 • 35 citations

Nerve growth factor promotes the differentiation of pituitary mammotroph cells in vitro.

1995 • 35 citations

High affinity agonist binding to the dopamine D3 receptor: chimeric receptors delineate a role for intracellular domains.

1994 • 35 citations

Dopamine D4‐Like Receptor Elevation in Schizophrenia: Cloned D2 and D4 Receptors Cannot Be Discriminated by Raclopride Competition Against [³H]Nemonapride

1995 • 34 citations

Dopamine Stimulates K⁺ Efflux in the Chick Retina via D₁ Receptors Independently of Adenylyl Cyclase Activation

1993 • 34 citations

Endogenous dopamine regulates phosphate reabsorption but not NaK-ATPase in spontaneously hypertensive rat kidneys.

1994 • 34 citations

Renal dopamine receptors and pre- and post-cAMP-mediated Na+ transport defect in spontaneously hypertensive rats

1992 • 34 citations

Estrogen receptors in the cardiovascular system

1996 • 33 citations

Characteristics of the vascular dopamine receptor: comparison with other receptors.

1978 • 33 citations

Recent developments in alcoholism:genetic transmission.

1993 • 33 citations

The D2 Dopamine Receptor Gene and Alcoholism: A Genetic Effect in the Liability for Alcoholism

1994 • 32 citations

Localization of dopamine-1 receptors along the microdissected rat nephron

1991 • 32 citations

Dopamine D2 receptor gene expression and binding sites in adrenal medulla and pheochromocytoma.

1994 • 32 citations

D₂Dopamine Receptors on Bovine Chromaffin Cell Membranes: Identification and Characterization by [³H]N-Methylspiperone Binding

1987 • 32 citations

Dopamine1 receptors in rat kidneys identified with 125I-Sch 23982

1988 • 31 citations

Dopamine Inhibits the Aldosterone Response to Upright Posture*

1986 • 31 citations

Nephron specificity of dopamine receptor-adenylyl cyclase defect in spontaneous hypertension

1993 • 31 citations

BROMOCRIPTINE-INDUCED MODULATION OF PLASMA ALDOSTERONE RESPONSE TO ACUTE STIMULATIONS

1979 • 31 citations

Comparison of the effects of fenoldopam, SK&F R-87516 and dopamine on renal arterioles in vitro

1986 • 31 citations

Reserpine treatment stimulates enkephalin and D2 dopamine receptor gene expression in the rat striatum

1992 • 30 citations

Transfected D2 short dopamine receptors inhibit voltage-dependent potassium current in neuroblastoma x glioma hybrid (NG108-15) cells.

1993 • 30 citations

A Renal Dopamine-1 Receptor Defect in Two Genetic Models of Hypertension

1990 • 30 citations

Effect of Decreased Dopamine Synthesis on the Development of Hypertension Induced by Salt Loading in Spontaneously Hypertensive Rats

1987 • 29 citations

Desensitization of DA1 dopamine receptors coupled to adenylyl cyclase in opossum kidney cells

1991 • 29 citations

Dopamine is taken up from the circulation by, and released from, local noradrenergic varicose axon terminals in zona glomerulosa of the rat: a neurochemical and immunocytochemical study

1993 • 29 citations

Pharmacology and biochemistry of dopamine receptors in the central nervous system and peripheral tissue.

1986 • 28 citations

Effect of dopamine on phosphate reabsorption in isolated perfused rabbit proximal tubules.

1983 • 28 citations

Role of Endogenous Dopamine in the Natriuretic Response to Various Degrees of Iso-Osmotic Volume Expansion in Rats

1991 • 28 citations

Dopaminergic stimulation of cAMP accumulation in cultured rat mesangial cells

1987 • 28 citations

A Dopamine-responsive Domain in the N-terminal Sequence of Pit-1

1995 • 27 citations

Analysis of new D4 dopamine receptor (DRD4) coding region variants and TH microsatellite in the Old Order Amish family (OOA110)

1994 • 27 citations

Suppressed dopaminergic activity and water‐sodium handling in the kidneys at the prehypertensive stage of essential hypertension

1990 • 27 citations

Stimulation of lactotrope differentiation in vitro by fibroblast growth factor.

1994 • 27 citations

Selective peripheral dopamine-1 receptor stimulation. Differential responses to sodium loading and depletion in humans.

1990 • 27 citations

Lack of coupling of D-2 receptors to adenylate cyclase in GH-3 cells exposed to epidermal growth factor. Possible role of a differential expression of Gi protein subtypes.

1991 • 27 citations

Abnormal regulation of renal proximal tubule Na(+)-K(+)-ATPase by G proteins in spontaneously hypertensive rats

1994 • 26 citations

Linkage Analysis of the D1 Dopamine Receptor Gene and Manic Depression in Six Families

1992 • 26 citations

Proximal tubular dopamine production regulates basolateral Na-K-ATPase

1992 • 26 citations

Pharmacological characterization and autoradiographic localization of dopamine receptors in the human adrenal cortex

1994 • 25 citations

Dopamine selectively inhibits angiotensin II-induced aldosterone secretion by interacting with D-2 receptors.

1988 • 25 citations

Dopamine-1 receptors in the proximal convoluted tubule of Dahl rats: defective coupling to adenylate cyclase

1995 • 25 citations

DA1 dopamine receptors in renal cortical collecting duct

1991 • 25 citations

The Pathophysiological Role of Renal Dopamine, Kallikrein Kinin and Prostaglandin Systems in Essential Hypertension

1987 • 25 citations

Nerve growth factor and bromocriptine: a sequential therapy for human bromocriptine-resistant prolactinomas

1995 • 24 citations

Dopamine selectively inhibits aldosterone responses to angiotensin II in humans.

1986 • 23 citations

Enhanced dopamine renal responsiveness in patients with hypertension

1986 • 22 citations

High salt diet down‐regulates proximal tubule Na+, K⁺‐ATPase activity in Dahl salt‐resistant but not in Dahl salt‐sensitive rats: evidence of defective dopamine regulation

1992 • 22 citations

Contrasting Dopaminergic Patterns in two Forms of Genetic Hypertension

1987 • 22 citations

Mechanism of dopamine inhibition of renal phosphate transport.

1992 • 22 citations

Selective dopamine-1 receptor stimulation produces natriuresis by a direct tubular action.

1986 • 22 citations

A Genetic Linkage Study of Bipolar Disorder and 13 Markers on Chromosome 11 Including the D2 Dopamine Receptor

1993 • 21 citations

Locally formed dopamine stimulates cAMP accumulation in LLC-PK1 cells via a DA1 dopamine receptor

1991 • 21 citations

Renal Dopamine and Sodium Excretion

1990 • 21 citations

Mechanisms involved in the interaction of dopamine with angiotensin II on aldosterone secretion in isolated and cultured rat adrenal glomerulosa cells

1991 • 20 citations

Dopamine blocks T-type calcium channels in cultured rat adrenal glomerulosa cells.

1994 • 20 citations

Renal dopamine and the tubular handling of sodium

1995 • 20 citations

Chronic Dopamine D₂Receptor Activation Does Not Affect Survival and Differentiation of Cultured Dopaminergic Neurons: Morphological and Neurochemical Observations

1993 • 19 citations

Five years’ experience with y‐ν‐glutamyl L‐dopa: a relatively renally specific dopaminergic prodrug in man

1990 • 19 citations

Multiple Control of Calcium Channel Gating by Dopamine D₂ Receptors in Frog Pituitary Melanotrophs^a

1993 • 19 citations

Autoradiographic localization of dopamine DA‐1 receptors in the rat renal vasculature using [³H]‐SCH 23390 as a ligand

1990 • 19 citations

Further evidence against the coupling of dopamine receptors to phosphoinositide hydrolysis in rat striatum

1990 • 19 citations

Attenuated Renal Production of Dopamine in Patients with Low Renin Essential Hypertension

1989 • 19 citations

A Regulatory Protein

1981 • 18 citations

Expression and functional characterisation of a synthetic version of the human D₄dopamine receptor in a stable human cell line

1994 • 18 citations

Role of dopamine receptors and the utility of dopamine agonists in heart failure.

1990 • 18 citations

Dietary Sodium Intake and Urinary Dopamine and Sodium Excretion During the Course of Blood Pressure Development in DAHL Salt-Sensitive and Salt-Resistant Rats

1987 • 18 citations

Effect of dopamine2 blockade on renal function under varied sodium intake.

1994 • 16 citations

Renal Dopamine Containing Nerves

1990 • 16 citations

Involvement of Endogenous Dopamine and Da-1 Receptors in the Renal Effects of Atrial Natriuretic Factor in Rats

1991 • 15 citations

Pharmacotherapy of schizophrenia: a review.

1994 • 15 citations

Lack of Renal Dopamine Production During Acute Volume Expansion in Dahl Salt-Sensitive Rats

1994 • 15 citations

Dopamine Produces Forearm Vasodilatation Following ??- Adrenoceptor Blockade by an Action on Vascular Dopamine (DA1Receptors in Man

1987 • 15 citations

DA₁Receptor Mediated Regulation of Na⁺-H⁺Antiport Activity in Rat Renal Cortical Brush Border Membrane Vesicles

1992 • 15 citations

Effect of reserpine treatment on enkephalin mRNA level in the rat striatum: an in situ hybridization study

1995 • 15 citations

Expression of Functional D₂ Dopamine Receptors Following Differentiation of Y‐79 Human Retinoblastoma Cells

1990 • 15 citations

Linkage analysis between schizophrenia and a microsatellite polymorphism for the D5 dopamine receptor gene

1994 • 14 citations

Characterization with 3H-haloperidol of the dopamine receptor in the rat kidney particulate preparation.

1980 • 14 citations

Dopaminergic defect in hypertension

1993 • 13 citations

Mechanisms of dopamine effects on Na-K-ATPase activity in Madin-Darby canine kidney (MDCK) epithelial cells

1995 • 13 citations

Cloning of the porcine D1A dopamine receptor gene expressed in renal epithelial LLC-PK1 cells

1995 • 13 citations

Epidermal Growth Factor Treatment Induces D2 Dopamine Receptors Functionally Coupled to Delayed Outward Potassium Current (l<sub>K</sub>) in GH4C1 Clonal Anterior Pituitary Cells

1994 • 13 citations

Differential effects of amphetamine isomers on SN self-stimulation: Evidence for DA neuron subtypes

1983 • 12 citations

Comparison of the Central and Renal Dopamine-1 Receptor

1990 • 12 citations

Dopamine D1 receptor mRNA in rat kidney: localization by in situ hybridization

1991 • 12 citations

Dopamine DA-2 receptor sites in the rat renal cortex: A light microscope autoradiographic study

1991 • 11 citations

Dopamine receptors mediating inhibition of the cyclic adenosine monophosphate generating system in the rat renal cortex

1991 • 11 citations

Dopaminergic Modulation of the Renal Effect of Arginine-Vasopressin in Water-Loaded Rats

1985 • 10 citations

Characterization of the dopamine receptor expressed by rat glomerular mesangial cells in culture

1992 • 10 citations

Increased Urinary Dopamine in Salt Loaded Rats

1977 • 10 citations

Studies concerning dopamine diuresis in the rat.

1976 • 10 citations

POSSIBLE ROLE OF INTRARENALLY PRODUCED DOPAMINE IN PHOSPHATE REGULATION

1976 • 9 citations

Pharmacological characterization of rat renal medulla dopamine-sensitive cyclic adenosine monophosphate generating system.

1990 • 9 citations

MODULATION OF ADRENAL CATECHOLAMINE RELEASE BY DA₂ DOPAMINE RECEPTORS IN THE ANAESTHETIZED DOG

1988 • 9 citations

Increased Dopamine-Induced Nephrogenous cAMP Formation in Hypertension

1991 • 8 citations

Effect of DA1 Receptor Blockade with SCH 23390 on the Renal Response to Electrical Stimulation of the Renal Nerves

1986 • 8 citations

Specific binding of 125I SCH 23982, a selective dopamine (D1) receptor ligand to plasma membranes derived from human kidney cortex

1989 • 8 citations

The Heterogeneity of Dopamine Involvement in Essential Hypertension

1989 • 7 citations

Renal Dopamine and Changes in Dopamine Receptor Ligand Binding During High Sodium Intake

1991 • 7 citations

Demonstration of Vascular Dopamine Receptors in the Human Forearm Arterial Circulation

1986 • 6 citations

Stimulation of Renal Dopamine Production During Acute Volume Expansion Requires the Presence of Intact Vagi But not Renal Nerves

1992 • 6 citations

EFFECT OF APOMORPHINE ON ADRENAL MEDULLARY CATECHOLAMINE LEVELS

1989 • 6 citations

Long-Term Renal Handling of Sodium and Calcium in Spontaneously Hypertensive Rats

1992 • 6 citations

Effects of dopamine, high potassium concentration and field stimulation on the secretion of aldosterone by the perfused rat adrenal gland

1992 • 6 citations

Dopaminergic Receptor Mechanisms Modulating the Renin-Angiotensin System and Aldosterone Secretion

1989 • 6 citations

New classes of selective D-1 dopamine receptor antagonist provide further evidence for two directions of D-1:D-2 interaction

1992 • 5 citations

Inhibition of the aldosterone response to sodium depletion in man by stimulation of dopamine DA2 receptors

1988 • 5 citations

Role of Renal Nerves and Dopamine on Prostaglandin E Release from the Kidney of Rats

1987 • 3 citations

Autoradiographic localization of dopamine D1 receptors in human renal cortex

1989 • 2 citations

Pharmacological characterization of the dopamine receptor expressed by rat glomerular mesangial cells in culture

1990 • 2 citations

Binding of [3H]SCH23390 to a non-dopaminergic site in bovine kidney

1992 • 2 citations