Regionally specific effects of atypical antipsychotic drugs on striatal Fos expression: The nucleus accumbens shell as a locus of antipsychotic action

Clozapine for the Treatment-Resistant Schizophrenic

1988 • 4,030 citations

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1990 • 2,630 citations

The regulation and function of c-fos and other immediate early genes in the nervous system

1990 • 2,392 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

Expression of c- fos Protein in Brain: Metabolic Mapping at the Cellular Level

1988 • 1,916 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

The use of c-fos as a metabolic marker in neuronal pathway tracing

1989 • 1,390 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

1989 • 1,313 citations

Specificity in the projection patterns of accumbal core and shell in the rat

1991 • 1,186 citations

Cloning and expression of a rat D2 dopamine receptor cDNA

1988 • 1,125 citations

Role of ion flux in the control of c-fos expression

1986 • 1,006 citations

The neostriatal mosaic: II. Patch- and matrix-directed mesostriatal dopaminergic and non-dopaminergic systems

1987 • 788 citations

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

The neostriatal mosaic: compartmental distribution of calcium-binding protein and parvalbumin in the basal ganglia of the rat and monkey.

1985 • 633 citations

Parallel Association of Fos and Jun Leucine Zippers Juxtaposes DNA Binding Domains

1989 • 607 citations

Neuroleptics increase C-FOS expression in the forebrain: Contrasting effects of haloperidol and clozapine

1992 • 477 citations

Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell

1992 • 457 citations

Acute Effects of Typical and Atypical Antipsychotic Drugs on the Release of Dopamine from Prefrontal Cortex, Nucleus Accumbens, and Striatum of the Rat: An In Vivo Microdialysis Study

1990 • 407 citations

Heterogeneity of striatal and limbic dopamine innervation: Highly fluorescent islands in developing and adult rats

1972 • 404 citations

Two transpallidal pathways originating in the rat nucleus accumbens

1990 • 388 citations

Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes.

1984 • 348 citations

D2 dopamine receptor antagonists induce fos and related proteins in rat striatal neurons

1990 • 344 citations

D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics

1989 • 322 citations

Correspondence between the Dopamine islands and striosomes of the mammalian striatum

1984 • 283 citations

Neurotensin: perchance an endogenous neuroleptic?

1980 • 272 citations

Neural mechanisms in disorders of movement

1989 • 270 citations

Mechanisms of action of atypical antipsychotic drugs

1991 • 254 citations

Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos.

1990 • 247 citations

The developing neostriatum of the rabbit: Correlation of fluorescence histochemistry, electron microscopy, endogenous dopamine levels, and [3H]dopamine uptake

1972 • 223 citations

Remoxipride, a new potential antipsychotic compound with selective anti-dopaminergic actions in the rat brain

1984 • 213 citations

Pharmacological characterization of the receptor mediating electrophysiological responses to dopamine in the rat medial prefrontal cortex: a microiontophoretic study.

1989 • 201 citations

Metoclopramide-induced movement disorders. Clinical findings with a review of the literature

1989 • 190 citations

Representation of the body by single neurons in the dorsolateral striatum of the awake, unrestrained rat

1991 • 183 citations

Differential effect of neuroleptic drugs on dopamine turnover in the extrapyramidal and limbic system

1976 • 176 citations

Induction of c‐fos mRNA Expression in Rat Striatum by Neuroleptic Drugs

1990 • 165 citations

Topographical distribution of dopaminergic innervation and of dopaminergic receptors in the rat striatum. I. Microestimation of [3H]dopamine uptake and dopamine content in microdiscs

1976 • 164 citations

Stress Selectively Increases Fos Protein in Dopamine Neurons Innervating the Prefrontal Cortex

1991 • 137 citations

Mechanisms of striatal pattern formation: conservation of mammalian compartmentalization

1990 • 132 citations

Clinical profile of remoxipride ‐ a combined analysis of a comparative double‐blind multicentre trial programme

1990 • 132 citations

Compartments in rat dorsal and ventral striatum revealed following injection of 6-hydroxydopamine into the ventral mesencephalon

1991 • 124 citations

Differential effects of haloperidol and clozapine on neurotensin gene transcription in rat neostriatum

1992 • 120 citations

Comparison of the pharmacological characteristics of [3H]raclopride and [3H]SCH 23390 binding to dopamine receptors in vivo in mouse brain

1988 • 111 citations

Striatal C-fos induction by drugs and stress in neonatally dopamine-depleted rats given nigral transplants: Importance of NMDA activation and relevance to sensitization phenomena

1991 • 110 citations

A neurochemical heterogeneity of the rat striatum as measured by in vivo electrochemistry and microdialysis

1990 • 103 citations

Differential effects of antipsychotic drugs on the neurotensin concentration of discrete rat brain nuclei

1988 • 102 citations

The striatal mosaic in primates: Patterns of neuropeptide immunoreactivity differentiate the ventral striatum from the dorsal striatum

1991 • 97 citations

Dissociable motor roles of the rat's striatum conform to a somatotopic model.

1988 • 92 citations

The Prevalence of Tardive Dyskinesia in Neuroleptic-Treated Diabetics

1991 • 91 citations

Ergebnisse eines Doppelblindversuches von HF 1854^*(8-Chlor-11-(4-methyl-1-piperazinyl)-5H-dibenzo (b, e) (1,4) diazepin) im Vergleich zu Levomepromazin

1971 • 90 citations

Mutually dependent response elements in the Cis-regulatory region of the neurotensin/neuromedin N gene integrate environmental stimuli in PC12 cells

1990 • 85 citations

Biochemical pharmacology of the atypical neuroleptic remoxipride

1990 • 84 citations

Variation in the ability of neuroleptics to block the inhibitory influence of dopaminergic neurons on the activity of cells in the rat prefrontal cortex

1986 • 80 citations

Dissociable motor roles of the rat's striatum conform to a somatotopic model.

1988 • 80 citations

Effects of acute and long-term treatment with neuroleptics on regional telencephalic neurotensin levels in the male rat

1986 • 78 citations

Effects of dopamine depletion on striatal neurotensin: biochemical and immunohistochemical studies

1989 • 73 citations

Neuropharmacological and behavioural properties of remoxipride in the rat

1990 • 71 citations

Metoclopramide: Antipsychotic efficacy of a drug lacking potency in receptor models

1980 • 58 citations

The Current Status of Neurotensin‐Dopamine Interactions

1992 • 51 citations

Progress in Parkinson's disease research--2

1992 • 50 citations

Distinct factors bind the AP-1 consensus sites in gibbon ape leukemia virus and simian virus 40 enhancers

1989 • 50 citations

Distribution of remoxipride to the human brain and central D2‐ dopamine receptor binding examined in vivo by PET

1990 • 49 citations

Clozapine for the treatment-resistant schizophrenic: results of a US multicenter trial

1989 • 49 citations

MPTP produces a pattern of nigrostriatal degeneration which coincides with the mosaic organization of the caudate nucleus

1988 • 48 citations

Subsets of neurotensin-immunoreactive neurons revealed following antagonism of the dopamine-mediated suppression of neurotensin immunoreactivity in the rat striatum

1992 • 47 citations

Regional Distribution of Neurotransmitter Synthesizing Enzymes in the Basal Ganglia of Human Brain

1980 • 46 citations

Comparative Psychotropic Effects of Metoclopramide and Prochlorperazine in Normal Subjects

1975 • 44 citations

[Effect profile of a chemically new broad spectrum neuroleptic of the dibenzo-diazepine group].

1966 • 40 citations

Dopamine receptors and ergot drugs. Evidence that an ergolene derivative is a differential agonist at subcortical limbic dopamine receptors

1978 • 38 citations

The prevalence of schizophrenia in three counties in Ireland

1990 • 34 citations

Acute and chronic treatment with neuroleptics: similarities and differences in their action on nigrostriatal, mesolimbic, and mesocortical dopaminergic neurons.

1977 • 31 citations

Experiences of long‐term treatment with remoxipride: efficacy and tolerability

1990 • 25 citations

New selective dopamine D-2 antagonists as antipsychotic agents. Pharmacological, chemical, structural and theoretical considerations.

1987 • 25 citations

Remoxipride and haloperidol in schizophrenia: a double‐blind multicentre study.

1990 • 24 citations

Cooperative Regulation of Neurotensin/Neuromedin N Gene Expression in PC12 Cells Involves AP‐1 Transcription Factors

1992 • 23 citations

Remoxipride versus thioridazine in elderly psychotic patients

1990 • 21 citations

A double‐blind multicentre study comparing remoxipride, controlled release formulation, with haloperidol in schizophrenia

1990 • 21 citations

A double-blind comparative study of remoxipride and haloperidol in schizophrenic and schizophreniform disorders

1990 • 19 citations

A double‐blind comparative study of remoxipride and thioridazine in the acute phase of schizophrenia

1990 • 19 citations

Computer-assisted image analysis techniques allow a characterization of the compartments within the basal ganglia. Focus on functional compartments produced by d-amphetamine activation of the c-fos gene and its relationship to the glucocorticoid receptor

1991 • 16 citations

Selective dopamine D2 antagonist and prolactin response in acute schizophrenia — Results from remoxipride studies

1990 • 12 citations

The unique effect of remoxipride on dopamine utilization in the basal ganglia

1991 • 9 citations