Exclusion of Linkage Between Schizophrenia and the D2 Dopamine Receptor Gene Region of Chromosome 11q in 112 Irish Multiplex Families

A Coefficient of Agreement for Nominal Scales

1960 • 37,524 citations

Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

1989 • 3,458 citations

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

1990 • 2,505 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

Dopamine in schizophrenia: a review and reconceptualization

1991 • 1,963 citations

Schizophrenia: The epigenetic puzzle

1982 • 1,194 citations

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

1991 • 1,157 citations

Cloning and expression of a rat D2 dopamine receptor cDNA

1988 • 1,125 citations

Positron Emission Tomography Reveals Elevated D ₂ Dopamine Receptors in Drug-Naive Schizophrenics

1986 • 935 citations

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

1981 • 910 citations

Dopamine receptors and the dopamine hypothesis of schizophrenia

1987 • 867 citations

The Dopamine Hypothesis of Schizophrenia: A Review*

1976 • 862 citations

The Roscommon Family Study

1993 • 712 citations

Localization of a susceptibility locus for schizophrenia on chromosome 5

1988 • 624 citations

Amphetamine Psychosis: A "Model" Schizophrenia Mediated by Catecholamines

1973 • 590 citations

INCREASED DOPAMINE-RECEPTOR SENSITIVITY IN SCHIZOPHRENIA

1978 • 513 citations

The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP.

1989 • 423 citations

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

1990 • 396 citations

Evidence against linkage of schizophrenia to markers on chromosome 5 in a northern Swedish pedigree

1988 • 394 citations

Use of cyclosporin a in establishing epstein-barr virus-transformed human lymphoblastoid cell lines

1984 • 355 citations

Testing for heterogeneity of recombination fraction values in Human Genetics

1963 • 303 citations

The Structured Interview for Schizotypy (SIS): A Preliminary Report

1989 • 291 citations

Genetic linkage and complex diseases, with special reference to psychiatric disorders

1990 • 283 citations

Allele frequency estimation from data on relatives.

1991 • 271 citations

Elevation of brain neuroleptic/dopamine receptors in schizophrenia

1980 • 220 citations

3H-spiperone binding sites in post-mortem brains from schizophrenic patients: Relationship to neuroleptic drug treatment, abnormal movements, and positive symptoms

1989 • 189 citations

Linkage analysis and family classification under heterogeneity

1983 • 177 citations

The Roscommon Family Study

1993 • 168 citations

Dinucleotide repeat polymorphisms at the D17S250 and D17S261 loci

1990 • 152 citations

The Antagonism of Amphetamine-Induced Symptomatology by a Neuroleptic

1974 • 149 citations

No linkage of chromosome 5q11-q13 markers to schizophrenia in Scottish families

1989 • 147 citations

Measuring the inflation of the lod score due to its maximization over model parameter values in human linkage analysis

1990 • 137 citations

A family history study of schizophrenia-related personality disorders

1984 • 132 citations

Refutation of the general single-locus model for the etiology of schizophrenia.

1982 • 131 citations

No Linkage Between D2 Dopamine Receptor Gene Region and Schizophrenia

1991 • 121 citations

Genetic Linkage: Interpreting Lod Scores

1992 • 108 citations

Exclusion of a schizophrenia susceptibility gene from the chromosome 5q11-q13 region: new data and a reanalysis of previous reports.

1990 • 105 citations

MECHANISM OF ACTION OF NEUROLEPTIC DRUGS

1978 • 103 citations

Segregation analysis of schizophrenia and related disorders.

1984 • 101 citations

Detecting linkage for genetically heterogeneous diseases and detecting heterogeneity with linkage data.

1986 • 85 citations

The detection of linkage and heterogeneity in nuclear families for complex disorders: one versus two marker loci.

1989 • 42 citations

Mixed-model segregation analysis of schizophrenia in the lindelius Swedish pedigrees

1990 • 41 citations

Distribution of lod scores under uncertain mode of inheritance.

1993 • 38 citations

STUDIEN UEBER VERERBUNG UND ENTSTEHUNG GEISTIGER STÖRUNGEN

1920 • 38 citations

Seven polymorphic loci mapping to human chromosomal region 11q22-qter

1988 • 33 citations

Dinucleotide repeat polymorphisms at the D11S419 and CD3D loci

1990 • 31 citations

Lack of Linkage to Chromosome 5q11-q13 Markers in Six Schizophrenia Pedigrees

1991 • 30 citations

Dinucleotide repeat polymorphism at the D4S174 locus

1990 • 29 citations

Report of a Workshop on Genetic Linkage Studies in Schizophrenia

1990 • 23 citations

A MspI polymorphism for the human porphobilinogen deaminase gene

1987 • 23 citations

Efficiency of lod scores for representing multiple locus linkage data

1985 • 16 citations

Genetic linkage analysis and homology relationships of genes located on human chromosome 11q

1991 • 15 citations

An anonymous human single copy genomic clone, D11S29 (L7) at 11q23, identifies a moderately frequent RFLP

1986 • 14 citations

Isolation and mapping of a polymorphic DNA sequence MCT128.1 on chromosome 11 [D11S285]

1988 • 13 citations

A polymorphic satellite sequence maps to the pericentric region of the bovine y chromosome

1989 • 8 citations

Linkage analysis of six schizophrenia pedigrees with 150 DNA markers

1991 • 4 citations

Linkage studies of schizophrenia with markers of chromosome-11q

1991 • 3 citations