Differential coupling of dopaminergic D2 receptors expressed in different cell types. Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in LtK- fibroblasts, hyperpolarization, and cytosolic-free Ca2+ concentration decrease in GH4C1 cells.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Cloning and expression of a rat D2 dopamine receptor cDNA

1988 • 1,125 citations

G Proteins: A Family of Signal Transducers

1986 • 975 citations

Studies of Inositol Phospholipid-Specific Phospholipase C

1989 • 914 citations

The GTP-binding protein, Go9 regulates neuronal calcium channels

1987 • 910 citations

GTP-binding proteins couple cardiac muscarinic receptors to a K channel

1985 • 868 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

1988 • 669 citations

GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels

1986 • 666 citations

G protein involvement in receptor-effector coupling.

1988 • 618 citations

The dopamine D2 receptor: two molecular forms generated by alternative splicing.

1989 • 596 citations

Dye Indicators of Membrane Potential

1979 • 566 citations

Cloning of the cDNA and gene for a human D2 dopamine receptor.

1989 • 488 citations

Molecular Properties of the Muscarinic Acetylcholine Receptor

1987 • 478 citations

Direct Activation of Mammalian Atrial Muscarinic Potassium Channels by GTP Regulatory Protein G _k

1987 • 441 citations

An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover

1987 • 398 citations

Oscillations of cytosolic Ca2+ in pituitary cells due to action potentials

1987 • 331 citations

Mechanisms of signal transduction at the dopamine D2 receptor

1989 • 312 citations

Effector Coupling Mechanisms of the Cloned 5-HT1A Receptor

1989 • 273 citations

Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas

1979 • 271 citations

Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell

1989 • 259 citations

Angiotensin II and dopamine modulate both cAMP and inositol phosphate productions in anterior pituitary cells. Involvement in prolactin secretion.

1986 • 245 citations

A guanine nucleotide-binding protein mediates the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line.

1986 • 243 citations

Selective coupling with K+ currents of muscarinic acetylcholine receptor subtypes in NG108-15 cells

1988 • 216 citations

Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin. Evidence for coupling of Ni to decreases in intracellular free calcium.

1985 • 190 citations

Dopamine inhibits cytosolic Ca2+ increases in rat lactotroph cells. Evidence of a dual mechanism of action.

1987 • 168 citations

The physiological role of calcium-dependent channels

1989 • 164 citations

Coupling of a cloned rat dopamine-D2 receptor to inhibition of adenylyl cyclase and prolactin secretion.

1990 • 149 citations

Free cytoplasmic Ca2+ and neurotransmitter release: studies on PC12 cells and synaptosomes exposed to alpha-latrotoxin.

1984 • 142 citations

Two different G-proteins mediate neuropeptide Y and bradykinin-stimulated phospholipid breakdown in cultured rat sensory neurons

1989 • 124 citations

Characterization of the cyclic AMP-independent actions of somatostatin in GH cells. I. An increase in potassium conductance is responsible for both the hyperpolarization and the decrease in intracellular free calcium produced by somatostatin.

1988 • 122 citations

Inhibition of inositol phosphate production is a late, Ca2+-dependent effect of D2 dopaminergic receptor activation in rat lactotroph cells.

1988 • 103 citations

Intracellular Recordings from Bovine Anterior Pituitary Cells: Modulation of Spontaneous Activity by Regulators of Prolactin Secretion

1986 • 85 citations

Somatostatin lowers the cytosolic free Ca2+ concentration in clonal rat pituitary cells (GH3 cells)

1984 • 81 citations

The Electrical Properties of Isolated Human Prolactin-Secreting Adenoma Cells and Their Modification by Dopamine*

1985 • 79 citations

Functional characterization of a rat dopamine D-2 receptor cDNA expressed in a mammalian cell line.

1989 • 77 citations

Single Cell Monitoring of Cytosolic Calcium Reveals Subtypes of Rat Lactotrophs with Distinct Responses to Dopamine and Thyrotropin-Releasing Hormone*

1987 • 67 citations

Dopamine does not attenuate phosphoinositide hydrolysis in rat anterior pituitary cells

1986 • 45 citations

Dopamine Receptor Stimulation Does Not Affect Phosphoinositide Hydrolysis in Slices of Rat Striatum

1988 • 44 citations

Is bacterial evolution random or selective?

1988 • 44 citations

Inhibitory Coupling of Hormone and Neurotransmitter Receptors to Adenylate Cyclase

1983 • 17 citations