The thalassemias: molecular mechanisms of human genetic disease.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Why genes in pieces?

1978 • 2,256 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Human fetal gγ- and Aγ-globin genes: Complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes

1980 • 947 citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

1982 • 937 citations

Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

1978 • 804 citations

Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1981 • 646 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Ubiquitous, interspersed repeated sequences in mammalian genomes.

1980 • 568 citations

The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions

1980 • 531 citations

The nucleotide sequence of the human β-globin gene

1980 • 502 citations

DNA sequence variants in the Gγ-, Aγ-, δ- and β-globin genes of man

1979 • 464 citations

Molecular cloning and characterization of the human β-like globin gene cluster

1980 • 452 citations

Conservation of the primary structure at the 3′ end of 18S rRNA from eucaryotic cells

1978 • 427 citations

A ubiquitous family of repeated DNA sequences in the human genome

1979 • 420 citations

Nonrandom association of polymorphic restriction sites in the β-globin gene cluster

1982 • 408 citations

Correlation of DNA exonic regions with protein structural units in haemoglobin

1981 • 394 citations

ANTENATAL DIAGNOSIS OF SICKLE-CELL ANÆMIA BY D.N.A. ANALYSIS OF AMNIOTIC-FLUID CELLS

1978 • 380 citations

A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing

1982 • 372 citations

The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene

1982 • 323 citations

Abnormal RNA processing due to the exon mutation of βE-globin gene

1982 • 309 citations

Haemoglobin Constant Spring—A Chain Termination Mutant ?

1971 • 305 citations

DNA sequences necessary for transcription of the rabbit β-globin gene in vivo

1982 • 298 citations

beta 0 thalassemia, a nonsense mutation in man.

1979 • 291 citations

Localization of the human insulin gene to the distal end of the short arm of chromosome 11.

1981 • 285 citations

Localization of the human α-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay

1977 • 282 citations

Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype.

1980 • 274 citations

Exons encode functional and structural units of chicken lysozyme.

1980 • 273 citations

Characterisation of deletions which affect the expression of fetal globin genes in man

1979 • 269 citations

Unstable β-globin mRNA in mRNA-deficient β0 thalassemia

1981 • 267 citations

Analysis of the β-δ-globin gene loci in normal and hb lepore DNA: Direct determination of gene linkage and intergene distance

1978 • 260 citations

The structure of a human α-globin pseudogene and its relationship to α-globin gene duplication

1980 • 259 citations

Triplicated alpha-globin loci in humans.

1980 • 241 citations

Base substitution in an intervening sequence of a beta+-thalassemic human globin gene.

1981 • 236 citations

β+ Thalassemia: Aberrant splicing results from a single point mutation in an intron

1981 • 235 citations

Structure and in Vitro Transcription of Human Globin Genes

1980 • 231 citations

α-Globin gene organisation in blacks precludes the severe form of α-thalassaemia

1979 • 229 citations

Gene deletion as the cause of α thalassaemia: Genetic lesion in homozygous α thalassaemia (hydrops fetalis)

1974 • 227 citations

Gene deletion as the cause of α thalassaemia: The severe form of α thalassaemia is caused by a haemoglobin gene deletion

1974 • 220 citations

Hereditary Persistence of Fetal Hemoglobin: A Study of 79 Affected Persons in 15 Negro Families in Baltimore

1963 • 215 citations

Polymorphism of DNA Sequence in the β-Globin Gene Region

1980 • 213 citations

Homology and concerted evolution at the α1 and α2 loci of human α-globin

1981 • 207 citations

Application of Endonuclease Mapping to the Analysis and Prenatal Diagnosis of Thalassemias Caused by Globin-Gene Deletion

1978 • 207 citations

A Sensitive New Prenatal Test for Sickle-Cell Anemia

1982 • 201 citations

BKV splice sequences based on analysis of preferred donor and acceptor sites

1979 • 198 citations

The primary structure of the human ε-globin gene

1980 • 195 citations

Identification of a Nondeletion Defect in α-Thalassemia

1977 • 194 citations

beta zero thalassemia in Sardinia is caused by a nonsense mutation.

1981 • 192 citations

γ-β-Thalassaemia studies showing that deletion of the γ- and δ-genes influences β-globin gene expression in man

1980 • 184 citations

The molecular basis of α-thalassemias: Frequent occurrence of dysfunctional α loci among non-Asians with Hb H disease

1979 • 183 citations

Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes.

1979 • 183 citations

The duplicated human alpha globin genes lie close together in cellular DNA.

1978 • 177 citations

Precise localization of human beta-globin gene complex on chromosome 11.

1979 • 175 citations

In Utero Diagnosis of Hemoglobinopathies

1974 • 172 citations

Improved Detection of the Sickle Mutation by DNA Analysis

1982 • 171 citations

THE PRESENT STATUS OF THE HETEROGENEITY OF FETAL HEMOGLOBIN IN β‐THALASSEMIA: AN ATTEMPT TO UNIFY SOME OBSERVATIONS IN THALASSEMIA AND RELATED CONDITIONS*

1974 • 167 citations

Prenatal Diagnosis of Hemoglobinopathies

1976 • 163 citations

The primary structures of two leghemoglobin genes from soybean

1982 • 162 citations

Deletion of α-globin genes in haemoglobin-H disease demonstrates multiple α-globin structural loci

1975 • 161 citations

Partial deletion of beta-globin gene DNA in certain patients with beta 0-thalassemia.

1979 • 159 citations

A novel α-globin gene arrangement in man

1980 • 159 citations

Physical mapping of the globin gene deletion in hereditary persistence of foetal haemoglobin (HPFH)

1980 • 157 citations

Hemoglobin Kenya, the product of fusion of γ and β polypeptide chains

1972 • 153 citations

Mutation in an intervening sequence splice junction in man.

1981 • 153 citations

Hemoglobin H Disease and Mental Retardation

1981 • 151 citations

RNA processing errors in patients with beta-thalassemia.

1982 • 150 citations

Direct identification of sickle cell anemia by blot hybridization.

1981 • 148 citations

Complete nucleotide sequence of the human δ-globin gene

1980 • 146 citations

Nucleotide sequence homology at 12 intron–exon junctions in the chick ovalbumin gene

1978 • 145 citations

Evolution of the Hemoglobin S and C Genes in World Populations

1980 • 144 citations

Prenatal Diagnosis of α-Thalassemia

1976 • 142 citations

Differentiation of the mRNA transcripts originating from the alpha 1- and alpha 2-globin loci in normals and alpha-thalassemics.

1981 • 141 citations

HÆMOGLOBIN-H DISEASE DUE TO A UNIQUE HÆMOGLOBIN VARIANT WITH AN ELONGATED α-CHAIN

1971 • 141 citations

Globin structural mutant α125Leu→Pro is a novel cause of α-thalassaemia

1982 • 141 citations

Cloning and complete nucleotide sequence of human 5'-alpha-globin gene.

1980 • 136 citations

RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.

1979 • 136 citations

Restriction endonuclease mapping of the human γ globin gene loci

1979 • 129 citations

Nonsense and frameshift mutations in beta 0-thalassemia detected in cloned beta-globin genes.

1981 • 129 citations

Gene deletions in alpha thalassemia prove that the 5' zeta locus is functional.

1980 • 124 citations

An intron nucleotide sequence variant in a cloned β⁺-thalassaemia globin gene

1981 • 124 citations

The duplicated human α-globin genes: Their relative expression as measured by RNA analysis

1981 • 123 citations

Model for antenatal diagnosis of β-thalassaemia and other monogenic disorders by molecular analysis of linked DNA polymorphisms

1980 • 121 citations

A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobin

1982 • 121 citations

Abnormal RNA splicing causes one form of α thalassemia

1982 • 120 citations

Quantitative Deficiency of Chain-Specific Globin Messenger Ribonucleic Acids in the Thalassemia Syndromes

1973 • 120 citations

Hemoglobin E: Distribution and population dynamics

1967 • 118 citations

Alternatives for splicing: Recognizing the ends of introns

1980 • 113 citations

mRNA-deficint β^°-thaladssemia results from a single nucleotide deletion

1982 • 111 citations

The insulin gene is located on chromosome 11 in humans

1980 • 109 citations

Decreased Globin Messenger RNA in Thalassemia Detected by Molecular Hybridization

1973 • 108 citations

The deletion in a type of δ0-β0-thalassaemia begins in an inverted AluI repeat

1982 • 107 citations

beta-Thalassemia in a Kurdish Jew. Single base changes in the T-A-T-A box.

1982 • 106 citations

The 3′ untranslated regions of the duplicated human α-globin genes are unexpectedly divergent

1980 • 106 citations

The relationship between coding sequences and function in haemoglobin

1980 • 106 citations

A nucleotide change at a splice junction in the human beta-globin gene is associated with beta 0-thalassemia.

1981 • 105 citations

Haemoglobin Icaria, a new chain-termination mutant which causes α thalassaemia

1974 • 104 citations

Changes in restricted human cellular DNA fragments containing globin gene sequences in thalassemias and related disorders

1978 • 104 citations

HÆMOGLOBIN TAK: A VARIANT WITH ADDITIONAL RESIDUES AT THE END OF THE β-CHAINS

1971 • 103 citations

Defective synthesis of HbE is due to reduced levels of βE mRNA

1980 • 101 citations

Beta thalassemia: Mutations which affect processing of the β-globin mRNA precursor

1980 • 101 citations

Estimation of genetic variation at the DNA level from restriction endonuclease data.

1981 • 100 citations

Characterization of globin domains: Heme binding to the central exon product

1980 • 100 citations

A New Genetic Basis for Hemoglobin-H Disease

1980 • 99 citations

ANTENATAL DIAGNOSIS OF SICKLE CELL ANAEMIA BY DIRECT ANALYSIS OF THE SICKLE MUTATION

1981 • 98 citations

δβ-Thalassemia is due to a gene deletion

1976 • 97 citations

Heterogeneity in the molecular basis of hereditary persistence of fetal haemoglobin

1980 • 97 citations

Hemoglobin Indianapolis (beta 112[G14] arginine). An unstable beta-chain variant producing the phenotype of severe beta-thalassemia.

1979 • 96 citations

PRENATAL DIAGNOSIS OF β-THALASSÆMIA AND SICKLE-CELL ANÆMIA

1977 • 91 citations

Assignment of human beta-, gamma-, and delta-globin genes to the short arm of chromosome 11 by chromosome sorting and DNA restriction enzyme analysis.

1979 • 91 citations

Abnormally spliced messenger RNA in erythroid cells from patients with β+ thalassemia and monkey cells expressing a cloned β+-thalassemic gene

1982 • 91 citations

Molecular comparison of delta beta-thalassemia and hereditary persistence of fetal hemoglobin DNAs: evidence of a regulatory area?

1982 • 91 citations

Estimating genetic divergence and genetic variability with restriction endonucleases.

1981 • 87 citations

Hemoglobin Koya Dora: high frequency of a chain termination mutant.

1975 • 87 citations

Successful Application of Prenatal Diagnosis in a Pregnancy at Risk for Homozygous β-Thalassemia

1975 • 87 citations

Absence of messenger RNA and gene DNA for β-globin chains in hereditary persistence of fetal hemoglobin

1976 • 86 citations

Structure and expression of a cloned β°thalassaemic globin gene

1981 • 85 citations

Major rearrangement in the human β-globin gene cluster

1981 • 82 citations

Interaction of heterocellular hereditary persistence of foetal haemoglobin with β thalassaemia and sickle cell anaemia

1976 • 81 citations

Abnormal or absent β mRNA in β0 Ferrara and gene deletion in δβ thalassaemia

1976 • 80 citations

Two types of triplicateda-globin loci in humans

1981 • 79 citations

Use of restriction endonucleases for mapping the allele for beta s-globin.

1982 • 78 citations

Partial deletion of the α-globin structural gene in human α-thalassaemia

1980 • 77 citations

Demonstration of non-functional beta-globin mRNA in homozygous beta (0) thalassemia.

1975 • 77 citations

Globin gene deletion in HPFH, δ°β° thalassaemia and Hb Lepore disease

1979 • 75 citations

Deletion of the β-globin structure gene in hereditary persistence of foetal haemoglobin

1975 • 75 citations

Absence of Messenger RNA for Beta Globin Chain in β°-Thalassaemia

1974 • 73 citations

The structure of the human β-globin gene in β-thalassaemia

1979 • 73 citations

Duplication followed by deletion accounts for the structure of an Indian deletion β^o-thalassemia gene

1982 • 72 citations

Physical mapping of the globin gene deletion in (δβ)° - thalassaemia

1979 • 71 citations

Hemoglobin Cranston, an unstable variant having an elongated beta chain due to nonhomologous crossover between two normal beta chain genes.

1975 • 71 citations

Hemoglobin Wayne: a frameshift mutation detected in human hemoglobin alpha chains.

1976 • 68 citations

Human globin gene analysis for a patient with beta-o/delta beta-thalassemia.

1975 • 68 citations

Prenatal diagnosis of beta-thalassemias by amniocentesis: linkage analysis using multiple polymorphic restriction endonuclease sites.

1980 • 68 citations

F-Cell Production in Sickle Cell Anemia: Regulation by Genes Linked to β-Hemoglobin Locus

1981 • 68 citations

Presence of gene for β globin in homozygous β0 thalassaemia

1976 • 66 citations

Processing of human beta-globin mRNA precursor to mRNA is defective in three patients with beta+-thalassemia.

1980 • 66 citations

Hemoglobin Suan-Dok (α₂^109(G16)LEU-^ARGβ₂). an Unstable Variant Associated with α-Thalassemia

1979 • 66 citations

Linkage Analysis of Nondeletion Hereditary Persistence of Fetal Hemoglobin

1982 • 65 citations

Antenatal diagnosis of thalassaemia major.

1978 • 64 citations

Cloning and direct examination of a structurally abnormal human beta 0-thalassemia globin gene.

1980 • 63 citations

Variability in the amount of β-globin mRNA in β0 thalassemia

1978 • 63 citations

Isolation and sequence analysis of a hybrid δ-globin pseudogene from the brown lemur

1982 • 63 citations

Authentic beta-globin mRNA sequences in homozygous betaO-thalassemia.

1977 • 63 citations

Deletion of the A gamma-globin gene in G gamma-delta beta-thalassemia.

1979 • 61 citations

Localisation of the Gγ-, Aγ-, δ- and β-globin genes on the short arm of human chromosome 11

1979 • 61 citations

Nucleotide sequence of the 3′ terminal third of rabbit α-globin messenger RNA: Comparison with human α-globin messenger RNA

1977 • 56 citations

The synthesis of human haemoglobin A2 during erythroid maturation

1972 • 56 citations

Characterisation of a new α thalassemia 1 defect due to a partial deletion of the α globin gene complex

1980 • 54 citations

O2 binding properties of the product of the central exon of β-globin gene

1981 • 54 citations

Suppression of the nonsense mutation in homozygous β0 thalassaemia

1979 • 53 citations

Molecular basis of hemoglobin-H disease in the Mediterranean population

1979 • 53 citations

Heterocellular Hereditary Persistence of Fetal Haemoglobin (Heterocellular HPFH) and its Interaction with β Thalassaemia

1977 • 51 citations

NEGRO α-THALASSÆMIA IS CAUSED BY DELETION OF A SINGLE α-GLOBIN GENE

1979 • 50 citations

Hemoglobin Grady: The First Example of a Variant with Elongated Chains Due to an Insertion of Residues

1974 • 49 citations

Prenatal Diagnosis of Homozygous α-Thalassemia

1979 • 49 citations

Heterogeneity of DNA deletion in gamma delta beta-thalassemia.

1981 • 47 citations

Unequal crossing-over: a common basis of single alpha-globin genes in Asians and American blacks with hemoglobin-H disease.

1980 • 47 citations

Restriction mapping of a new deletion responsible for^Gγ(δβ)° thalassaemia

1981 • 47 citations

Characterization of β-globin mRNA in the β0 thalassemias

1978 • 46 citations

Hereditary persistence of foetal haemoglobin with β-chain synthesis in cis position (Gγ-β+-HPFH) in a negro family

1976 • 46 citations

Nucleotide sequence of 3' untranslated portion of human alpha globin mRNA

1977 • 44 citations

A novel rearrangement of the human βlike globin gene cluster

1981 • 44 citations

Synthesis of Haemoglobin Lepore

1972 • 44 citations

Acquired Haemoglobin H Disease in Leukaemia: Pathophysiology and Molecular Basis

1978 • 43 citations

Relative stability of alpha- and beta-globin messenger RNAs in homozygous beta+ thalassemia.

1977 • 43 citations

Heterogeneity of DNA fragments associated with the sickle-globin gene.

1979 • 43 citations

A G gamma type of the hereditary persistence of fetal hemoglobin with beta chain production in cis.

1975 • 42 citations

The chemical heterogeneity of the fetal hemoglobin of black newborn babies and adults: a reevaluation

1981 • 42 citations

Absence of Hæmoglobin A2 in an Adult

1962 • 42 citations

The β-globin gene is on the short arm of human chromosome 11

1980 • 42 citations

Molecular analysis of the beta-thalassemia phenotype associated with inheritance of hemoglobin E (alpha 2 beta2(26)Glu leads to Lys).

1981 • 41 citations

In Utero Diagnosis of Hemoglobinopathies

1974 • 41 citations

Genetic and molecular diversity in nondeletion Hb H disease.

1981 • 41 citations

Human globin gene expression: Control of β, δ and δβ chain production

1978 • 41 citations

Hemoglobin Petah Tikva (alpha 110 ala replaced by asp): a new unstable variant with alpha-thalassemia-like expression

1981 • 38 citations

Haemoglobin Constant Spring Synthesis in Red Cell Precursors

1974 • 38 citations

Proportion of hemoglobin G Philadelphia (alpha 268 Asn leads to Lys beta 2) in heterozygotes is determined by alpha-globin gene deletions.

1980 • 37 citations

The alpha-globin gene adjacent to the gene for HbQ-alpha 74 Asp replaced by His is deleted, but not that adjacent to the gene for HbG- alpha 30 Glu replaced by Gln; three-fourths of the alpha-globin genes are deleted in HbQ-alpha-thalassemia

1979 • 37 citations

beta-Thalassemia present in cis to a new beta-chain structural variant, Hb Vicksburg [beta 75 (E19)Leu leads to 0].

1981 • 37 citations

Anomaly in the γ chain heterogeneity of the newborn

1977 • 36 citations

Three mouse models of human thalassemia.

1981 • 36 citations

Direct demonstration of β-globin mRNA in homozygous Ferrara β0-thalassaemia patients

1977 • 36 citations

Hemoglobin Lepore Trait: Globin Synthesis in Bone Marrow and Peripheral Blood

1972 • 34 citations

FETAL BLOOD DRAWING

1975 • 34 citations

Localization of the site of recombination in formation of the Lepore Boston globin gene.

1981 • 33 citations

Two cloned β thalassemia genes are associated with amber mutations at codon 39

1981 • 33 citations

THE MOLECULAR BASIS FOR THE HAEMOGLOBIN BART'S HYDROPS FETALIS SYNDROME IN CYPRUS

1981 • 32 citations

The British type of non‐deletion HPFH: characterization of developmental changes in vivo and erythroid growth in vitro

1982 • 32 citations

Deletions in the alpha-globin gene complex in alpha-thalassemic mice.

1981 • 32 citations

Five nucleotide changes in the large intervening sequence of a β globin gene in a β⁺thalassemia patient

1982 • 32 citations

Hemoglobin Lincoln Park: a betadelta fusion (anti-Lepore) variant with an amino acid deletion in the delta chain-derived segment.

1978 • 31 citations

Synthesis in vitro of Anti-Lepore Haemoglobin

1973 • 31 citations

Instability of beta E-messenger RNA during erythroid cell maturation in hemoglobin E homozygotes.

1982 • 31 citations

Linkage of alpha G-Philadelphia to alpha-thalassemia in African-Americans .

1980 • 31 citations

Nucleotide sequences of the 3'-terminal untranslated region of messenger RNA for human beta globin chain.

1975 • 31 citations

The Genetic Basis of Hb Q‐H Disease

1980 • 31 citations

Human globin ψB₂is not a globin-related sequence

1982 • 29 citations

A Ghanaian Adult, Homozygous for Hereditary Persistence of Foetal Haemoglobin and Heterozygous for Elliptocytosis

1970 • 29 citations

Transcriptional and Post‐transcriptional Defects in β⁰‐Thalassaemia

1977 • 28 citations

High genetic polymorphism of hemoglobin disorders in Laos

1979 • 28 citations

A molecular basis for hemoglobin-H disease in American blacks.

1979 • 28 citations

A new nonsense mutation as the molecular basis for β° thalassaemia

1982 • 25 citations

Homozygous Delta Thalassemia in Japan

1980 • 25 citations

Restriction endonuclease maps of the β-like globin gene cluster in the British and Greek forms of HPFH, and for one example of^Gγβ⁺HPFH

1982 • 25 citations

Homozygous Delta-Thalassemia First Discovered in Japanese Family With Hereditary Persistence of Fetal Hemoglobin

1971 • 24 citations

The gamma-delta-beta-globin gene region in G gamma-beta +-hereditary persistence of fetal hemoglobin

1982 • 23 citations

Greek (^Aγ) variant of hereditary persistence of fetal haemoglobin: globin gene organization and studies of expression of fetal haemoglobins in clonal erythroid cultures

1982 • 22 citations

G gamma beta + type of hereditary persistence of fetal haemoglobin in association with Hb C.

1979 • 21 citations

α-Globin gene deletions associated with Hb J Tongariki

1982 • 20 citations

alpha thalassemia in black populations.

1980 • 20 citations

Restriction endonuclease analysis of human globin genes in cellular DNA

1978 • 19 citations

Alpha-gene deletions in black newborn infants with Hb Bart's

1980 • 17 citations

The Human Alpha-Globin Gene. The Protein Products of the Duplicated Genes Are Identical

1980 • 15 citations

Posttranscriptional defects in beta-globin messenger RNA metabolism in beta-thalassemia: abnormal accumulation of beta-messenger RNA precursor sequences.

1981 • 15 citations

Defects in DNA and globin messenger RNA in homozygotes for hemoglobin Lepore.

1979 • 15 citations

Isolation and characterization of cloned DNA: the delta and beta globin genes in homozygous beta + thalassemia

1981 • 14 citations

Hemoglobin H Disease from Algeria: Genetic and Molecular Characterization

1981 • 13 citations

Alpha-thalassemia in blacks is due to gene deletion.

1979 • 13 citations

A COMPARISON BETWEEN EVOLUTIONARY SUBSTITUTIONS AND VARIANTS IN HUMAN HEMOGLOBINS *

1974 • 13 citations

A case of homozygous δ thalassemia not due to a deletion of the δ globin structural gene

1981 • 12 citations

Absence of beta mRNA in beta0-thalassemia in Kurdish Jews

1978 • 12 citations

Five Families with Homozygous δ‐Thalassaemia in Japan

1980 • 11 citations

Imbalanced globin chain synthesis in cultured erythroid progenitor cells from thalassemic bone marrow and peripheral blood

1981 • 11 citations

Interaction Between Genes for Delta Thalassemia and Hereditary Persistence of Foetal Hemoglobin

1965 • 11 citations

Globin Chain Synthesis in Haemoglobin New York (β 113 Valine→Glutamic acid

1980 • 11 citations

Thalassemia with Complete Absence of Hemoglobin A<sub>2</sub> in an Adult

1965 • 11 citations

The molecular basis of hemoglobin Grady.

1981 • 9 citations

Hb Grady and alpha thalassemia: a contribution to the problem of the number of Hb alpha structural loci in man.

1976 • 9 citations

Prenatal diagnosis of ?-thalassemia using selective hemolysis of maternal cells contaminating fetal blood sample

1978 • 8 citations

Heterogeneity in ?0 thalassemia from Algeria: Genetic, clinical and molecular studies

1980 • 7 citations

The effect of alpha-thalassemia on the expression of the beta- thalassemia/HPFH heterozygote in a black family

1981 • 7 citations

Hb P-Nilotic in association with beta0-thalassemia: cis-mutation of a hemoglobin betaA chain regulatory determinant?

1979 • 7 citations

<i>β</i>-Thalassemia in Sicily

1978 • 7 citations

Prenatal diagnosis of heterozygous beta-thalassemia.

1976 • 7 citations

Restriction enzyme analysis of the β-globin gene in DNA from β°-thalassaemic subjects from Ferrara

1979 • 6 citations

Abnormal Hemoglobins Caused by Deletions: A Review

1979 • 6 citations

Interaction Between Beta and Delta Thalassemia and Hemoglobin D

1966 • 5 citations

The varied arrangement of the alpha globin genes in alpha thalassemia and Hb H disease in American blacks.

1980 • 5 citations

Analysis of Globin Gene Structure in Patients with β Thalassemia by Restriction Endonuclease Mapping

1981 • 5 citations

Thalassemia in Southern India Interaction of Genes for β<sup>+</sup>-, β°-, and δ° β°-ThaIassemia

1980 • 4 citations

Homozygous deletional α⁺ thalassaemia associated with unequal expression of the two remaining α₁ genes (α₁^A and α₁^Q)

1982 • 4 citations

A New Thalassemic Syndrome: Homozygous Hemoglobin S Disease Delta Thalassemia

1966 • 4 citations

Absence of Functional � - Globin Messenger Rna in Kurdish Jews With �0-Thalassemia

2015 • 2 citations

The Organization of the γ-δ-β Gene Complex in Normal and Thalassemia Cells

1980 • 1 citations