The alpha-globin gene adjacent to the gene for HbQ-alpha 74 Asp replaced by His is deleted, but not that adjacent to the gene for HbG- alpha 30 Glu replaced by Gln; three-fourths of the alpha-globin genes are deleted in HbQ-alpha-thalassemia

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose-ethidium bromide electrophoresis

1973 • 1,616 citations

Insertion of synthetic copies of human globin genes into bacterial plasmids

1978 • 350 citations

Gene deletion as the cause of α thalassaemia: Genetic lesion in homozygous α thalassaemia (hydrops fetalis)

1974 • 227 citations

Gene deletion as the cause of α thalassaemia: The severe form of α thalassaemia is caused by a haemoglobin gene deletion

1974 • 220 citations

Application of Endonuclease Mapping to the Analysis and Prenatal Diagnosis of Thalassemias Caused by Globin-Gene Deletion

1978 • 207 citations

Identification of a Nondeletion Defect in α-Thalassemia

1977 • 194 citations

Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes.

1979 • 183 citations

The duplicated human alpha globin genes lie close together in cellular DNA.

1978 • 177 citations

Deletion of α-globin genes in haemoglobin-H disease demonstrates multiple α-globin structural loci

1975 • 161 citations

Book Review: Man's Hæmoglobins

1967 • 138 citations

Two Haemoglobins Q, α74 (EF3) and α75 (EF4) Aspartic Acid→Histidine

1970 • 114 citations

Differences between - and -Chain Mutants of Human Haemoglobin and between - and -Thalassaemia. Possible Duplication of the -Chain Gene

1968 • 113 citations

Multiple Alpha Chain Loci for Human Haemoglobins: Hb J-Buda and Hb G-Pest

1972 • 106 citations

Alpha-chain Thalassemia and Hydrops Fetalis in Malaya: Report of Five Cases

1962 • 94 citations

Homozygous Hb J Tongariki: Evidence for Only One Alpha Chain Structural Locus in Melanesians

1970 • 88 citations

Hemoglobin Koya Dora: high frequency of a chain termination mutant.

1975 • 87 citations

Studies on the heterogeneity of hemoglobin

1962 • 77 citations

A Chemical Abnormality in Hemoglobin G from Chinese Individuals

1962 • 72 citations

A Haemoglobinopathy Involving Haemoglobin H and a New (Q) Haemoglobin

1958 • 69 citations

Synthesis of DNA complementary to separated human alpha and beta globin messenger RNAs.

1975 • 61 citations

Studies on the Proportion and Synthesis of Haemoglobin G Philadelphia in Red Cells of Heterozygotes, a Homozygote, and a Heterozygote for both Haemoglobin G and α Thalassaemia

1976 • 55 citations

Hemoglobin G Taichung: α74 Asp → His

1970 • 53 citations

Haemoglobin J Tongariki is associated with α thalassaemia

1978 • 50 citations

Trimodality in the proportion of hemoglobin G Philadelphia in heterozygotes: evidence for heterogeneity in the number of human alpha chain loci.

1976 • 50 citations

Prenatal Diagnosis of Homozygous α-Thalassemia

1979 • 49 citations

Hemoglobin Mahidol: a new hemoglobin α-chain mutant

1970 • 46 citations

An Abnormal Hæmoglobin in a Chinese: Hæmoglobin G

1958 • 44 citations

A New Hæmoglobin Variant (the ‘Honolulu Type’) in a Chinese

1961 • 37 citations

The Interaction of α‐Thalassaemia and Haemoglobin G Philadelphia

1976 • 32 citations

Selective restriction endonuclease cleavage of human globin genes.

1978 • 22 citations

Further Cases of Hb Q-H Disease (Hb Q-α Thalassemia)

1966 • 21 citations

Splenectomy in Two Cases of Haemoglobin Q-H-Disease (Hb Q-α-Thalassaemia)

1963 • 20 citations

Restriction endonuclease analysis of human globin genes in cellular DNA

1978 • 19 citations

Demonstration of Two alpha-Globin Genes per Human Haploid Genome for Normals and Hb J Mexico

1977 • 16 citations

Simple method for the isolation and purification of hemoglobin components

1976 • 10 citations