Defects in DNA and globin messenger RNA in homozygotes for hemoglobin Lepore.

The rabbit β-globin gene contains a large insert in the coding sequence

1977 • 422 citations

THE FUSION OF TWO PEPTIDE CHAINS IN HEMOGLOBIN LEPORE AND ITS INTERPRETATION AS A GENETIC DELETION

1962 • 331 citations

Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.

1978 • 254 citations

The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor.

1978 • 242 citations

Gene deletion as the cause of α thalassaemia: Genetic lesion in homozygous α thalassaemia (hydrops fetalis)

1974 • 227 citations

Gel Electrophoresis of Avian Leukosis and Sarcoma Viral RNA in Formamide: Comparison with Other Viral and Cellular RNA Species

1973 • 223 citations

Gene deletion as the cause of α thalassaemia: The severe form of α thalassaemia is caused by a haemoglobin gene deletion

1974 • 220 citations

THE PRESENT STATUS OF THE HETEROGENEITY OF FETAL HEMOGLOBIN IN β‐THALASSEMIA: AN ATTEMPT TO UNIFY SOME OBSERVATIONS IN THALASSEMIA AND RELATED CONDITIONS*

1974 • 167 citations

Organization of human δ- and β-globin genes in cellular DNA and the presence of intragenic inserts

1978 • 141 citations

Synthesis of extensive, possibly complete, DNA copies of poliovirus RNA in high yields and at high specific activities.

1976 • 137 citations

Quantitative Deficiency of Chain-Specific Globin Messenger Ribonucleic Acids in the Thalassemia Syndromes

1973 • 120 citations

Decreased Globin Messenger RNA in Thalassemia Detected by Molecular Hybridization

1973 • 108 citations

Hybridization of iodine-125-labeled ribonucleic acid

1973 • 107 citations

Changes in restricted human cellular DNA fragments containing globin gene sequences in thalassemias and related disorders

1978 • 104 citations

δβ-Thalassemia is due to a gene deletion

1976 • 97 citations

Absence of messenger RNA and gene DNA for β-globin chains in hereditary persistence of fetal hemoglobin

1976 • 86 citations

Abnormal human hemoglobins X. A study of hemoglobin leporeBoston

1965 • 80 citations

Abnormal or absent β mRNA in β0 Ferrara and gene deletion in δβ thalassaemia

1976 • 80 citations

Demonstration of non-functional beta-globin mRNA in homozygous beta (0) thalassemia.

1975 • 77 citations

Deletion of the β-globin structure gene in hereditary persistence of foetal haemoglobin

1975 • 75 citations

Absence of Messenger RNA for Beta Globin Chain in β°-Thalassaemia

1974 • 73 citations

Thalassemia Syndromes

2015 • 69 citations

Presence of gene for β globin in homozygous β0 thalassaemia

1976 • 66 citations

Authentic beta-globin mRNA sequences in homozygous betaO-thalassemia.

1977 • 63 citations

Studies on Hemoglobin Biosynthesis: Asynchronous Synthesis of Hemoglobin A and Hemoglobin A2 by Erythrocyte Precursors *

1965 • 62 citations

Relative numbers of human globin genes assayed with purified alpha and beta complementary human DNA.

1975 • 59 citations

Changes in globin messenger RNA content during erythroid cell differentiation.

1975 • 56 citations

The synthesis of human haemoglobin A2 during erythroid maturation

1972 • 56 citations

A direct estimate of the number of human γ-globin genes

1976 • 53 citations

Synthesis of Haemoglobin Lepore

1972 • 44 citations

Polyadenylate Sequences and Biologic Activity of Human Globin Messenger Ribonucleic Acid

1974 • 42 citations

Direct demonstration of β-globin mRNA in homozygous Ferrara β0-thalassaemia patients

1977 • 36 citations

A Limited Number of Globin Genes in Human DNA

1974 • 28 citations

beta-O-thalassemia from Algeria: genetic and molecular characterization

1977 • 24 citations

Studies of Globin Chain Synthesis and Globin mRNA Content in a Patient Homozygous for Hemoglobin Lepore

1978 • 19 citations

Globin synthesis of intact cells and activity of isolated mRNA in -thalassaemia.

1973 • 17 citations

Preparative polyacrylamide gel electrophoretic purification of human alpha- and beta-globin messenger RNAs.

1977 • 15 citations

Absence of beta mRNA in beta0-thalassemia in Kurdish Jews

1978 • 12 citations

Quantitation of human gamma globin genes and gamma globin mRNA with purified gamma globin complementary DNA.

1976 • 12 citations

Quantitation of human globin chain synthesis by cellulose acetate electrophoresis

1978 • 9 citations

Die bakteriologische Fleischuntersuchung.

1943 • 3 citations