γ-β-Thalassaemia studies showing that deletion of the γ- and δ-genes influences β-globin gene expression in man

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Studies on Abnormal Hemoglobins

1951 • 987 citations

A physical map of the DNA regions flanking the rabbit β-globin gene

1977 • 654 citations

The arrangement of simian virus 40 sequences in the DNA of transformed cells

1976 • 522 citations

beta 0 thalassemia, a nonsense mutation in man.

1979 • 291 citations

Characterisation of deletions which affect the expression of fetal globin genes in man

1979 • 269 citations

A method for the recovery of DNA from agarose gels

1978 • 262 citations

Analysis of the β-δ-globin gene loci in normal and hb lepore DNA: Direct determination of gene linkage and intergene distance

1978 • 260 citations

Recent developments in the molecular genetics of human hemoglobin

1979 • 199 citations

Partial deletion of beta-globin gene DNA in certain patients with beta 0-thalassemia.

1979 • 159 citations

Restriction endonuclease mapping of the human γ globin gene loci

1979 • 129 citations

Microchromatography of hemoglobins. II. A rapid method for the determination of hemoglobin A2.

1974 • 127 citations

Structure of the human fetal globin gene locus

1979 • 113 citations

Gamma-Beta Thalassemia: A Cause of Hemolytic Disease of the Newborn

1972 • 79 citations

Globin gene deletion in HPFH, δ°β° thalassaemia and Hb Lepore disease

1979 • 75 citations

From Gene to Protein: Information Transfer in Normal and Abnormal Cells

1979 • 73 citations

The structure of the human β-globin gene in β-thalassaemia

1979 • 73 citations

Physical mapping of the globin gene deletion in (δβ)° - thalassaemia

1979 • 71 citations

Isolation and partial sequence of recombinant plasmids containing human α-, β- and γ-globin cDNA fragments

1978 • 67 citations

Structure of the human G gamma-A gamma-delta-beta-globin gene locus.

1979 • 53 citations

Biosynthetic Ratio of Labelled Globin Chains in Human Reticulocytes, Determined by Electrophoresis on Cellulose Acetate

1978 • 18 citations

EXPRESSION OF CLONED VIRAL AND CHROMOSOMAL PLASMID-LINKED DNA IN COGNATE HOST CELLS

1979 • 8 citations

THE STRUCTURE AND EXPRESSION OF NORMAL AND ABNORMAL GLOBIN GENES

1979 • 3 citations