Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Nucleotide sequence of the rightward operator of phage lambda.

1975 • 2,068 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

1980 • 1,285 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis

1975 • 1,135 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

The ovalbumin gene - sequence of putative control regions

1980 • 996 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dna

1979 • 678 citations

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

1981 • 657 citations

Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1981 • 646 citations

Isolation and partial characterization of the Drosophila alcohol dehydrogenase gene.

1980 • 570 citations

The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene

1980 • 556 citations

The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions

1980 • 531 citations

The nucleotide sequence of the human β-globin gene

1980 • 502 citations

Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.

1980 • 471 citations

Simian virus 40 tandem repeated sequences as an element of the early promoter.

1981 • 462 citations

Inhibition of intractable, nucleases with ribonucleoside-vanadyl complexes: isolation of messenger ribonucleic acid from resting lymphocytes

1979 • 461 citations

Mapping temperature-sensitive and host-range mutations of adenovirus type 5 by marker rescue

1978 • 408 citations

Heterogeneity and 5′-terminal structures of the late RNAs of simian virus 40

1978 • 372 citations

Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome

1979 • 355 citations

Insertion of synthetic copies of human globin genes into bacterial plasmids

1978 • 350 citations

Isolation of Mutants of an Animal Virus in Bacteria

1980 • 341 citations

SV40 gene expression is modulated by the cooperative binding of T antigen to DNA

1981 • 300 citations

Spacer DNA sequences upstream of the T-A-T-A-A-A-T-A sequence are essential for promotion of H2A histone gene transcription in vivo.

1980 • 287 citations

The SV40 early region TATA box is required for accurate in vitro initiation of transcription

1981 • 269 citations

Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen.

1980 • 254 citations

Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication.

1980 • 244 citations

Altering Genotype and Phenotype by DNA-Mediated Gene Transfer

1980 • 242 citations

Structure and in Vitro Transcription of Human Globin Genes

1980 • 231 citations

DNA sequences preceding the rabbit beta-globin gene are required for formation in mouse L cells of beta-globin RNA with the correct 5' terminus.

1981 • 231 citations

DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2.

1981 • 216 citations

Expression of early genes of origin-defective mutants of simian virus 40.

1980 • 205 citations

Specificity of the S1 nuclease from Aspergillus oryzae.

1975 • 201 citations

Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence.

1980 • 195 citations

Origin-defective Mutants of SV40

1980 • 193 citations

Rabbit β-globin mRNA production in mouse L cells transformed with cloned rabbit β-globin chromosomal DNA

1979 • 191 citations

AUG is the only recognisable signal sequence in the 5′ non-coding regions of eukaryotic mRNA

1978 • 172 citations

Identification of a promoter component involved in positioning the 5' termini of simian virus 40 early mRNAs.

1981 • 162 citations

SV40 DNA transfection of cells in suspension: analysis of the efficiency of transcription and translation of T-antigen

1981 • 161 citations

Localization of DNA sequences necessary for transcription of the rabbit β-globin gene in vitro

1981 • 158 citations

High-fidelity transcription of 5S DNA injected into Xenopus oocytes.

1977 • 146 citations

Cloning and complete nucleotide sequence of human 5'-alpha-globin gene.

1980 • 136 citations

Expression of the chromosomal mouse βmaj-globin gene cloned in SV40

1979 • 135 citations

Introduction and expression of a rabbit beta-globin gene in mouse fibroblasts.

1979 • 129 citations

Removal of RNase activity from DNase by affinity chromatography on agarose-coupled aminophenylphosphoryl-uridlne-2′(3′)-phosphate

1977 • 98 citations

Expression of simian virus 40-rat preproinsulin recombinants in monkey kidney cells: use of preproinsulin RNA processing signals.

1981 • 94 citations

Transcription of Xenopus tDNAFormula and Sea Urchin Histone DNA Injected into the Xenopus Oocyte Nucleus

1978 • 82 citations

The 3$prime; terminal sequences of human $alpha; and $beta; globin messenger RNAs: Comparison with rabbit globin messenger RNA

1976 • 61 citations

A mouse globin gene promoter is functional in SV40

1980 • 48 citations

EXPRESSION OF β-GLOBIN GENES MODIFIED BY RESTRUCTURING AND SITE-DIRECTED MUTAGENESIS

1981 • 11 citations

Deleted Work

1955 • 0 citations