Cloning and complete nucleotide sequence of human 5'-alpha-globin gene.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

REGULATORY SEQUENCES INVOLVED IN THE PROMOTION AND TERMINATION OF RNA TRANSCRIPTION

1979 • 2,730 citations

Why genes in pieces?

1978 • 2,256 citations

Nucleotide sequence of the rightward operator of phage lambda.

1975 • 2,068 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Isolation of High‐Molecular‐Weight DNA from Mammalian Cells

1973 • 1,723 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

The ovalbumin gene - sequence of putative control regions

1980 • 996 citations

Resolution of Multiple Ribonucleic Acid Species by Polyacrylamide Gel Electrophoresis^*

1967 • 866 citations

Nucleotide sequence of an RNA polymerase binding site at an early T7 promoter.

1975 • 597 citations

The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions

1980 • 531 citations

The nucleotide sequence of the human β-globin gene

1980 • 502 citations

The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites

1978 • 409 citations

Insertion of synthetic copies of human globin genes into bacterial plasmids

1978 • 350 citations

Cloning Human Fetal γ Globin and Mouse α-Type Globin DNA: Preparation and Screening of Shotgun Collections

1978 • 350 citations

The evolution and sequence comparison of two recently diverged mouse chromosomal β-globin genes

1979 • 337 citations

The complete sequence of a chromosomal mouse α-globin gene reveals elements conserved throughout vertebrate evolution

1979 • 317 citations

Localization of the human α-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay

1977 • 282 citations

Characterisation of deletions which affect the expression of fetal globin genes in man

1979 • 269 citations

Structure of cloned DNA complementary to rat prolactin messenger RNA.

1980 • 262 citations

Comparison of Total Sequence of a Cloned Rabbit β-Globin Gene and Its Flanking Regions with a Homologous Mouse Sequence

1979 • 256 citations

Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.

1977 • 229 citations

Nucleotide sequence of an RNA polymerase binding site from the DNA of bacteriophage fd.

1975 • 209 citations

Chromosomal localization of human β globin gene on human chromosome 11 in somatic cell hybrids

1978 • 189 citations

Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes.

1979 • 183 citations

The duplicated human alpha globin genes lie close together in cellular DNA.

1978 • 177 citations

Complete nucleotide sequence of the human δ-globin gene

1980 • 146 citations

Characterization of globin domains: Heme binding to the central exon product

1980 • 100 citations

Sequence of promoter for coat protein gene of bacteriophage fd

1976 • 96 citations

Improved derivative of a phage λ EK2 vector for cloning recombinant DNA

1976 • 85 citations

Processing of the mouse β-globin mRNA precursor: at least two cleavage-ligation reactions are necessary to excise the larger intervening sequence

1979 • 84 citations

Complete nucleotide sequence of the 5′ noncoding region of human α- and β-globin mRNA

1977 • 81 citations

Mutagenesis in vitro by DNA polymerase from an RNA tumour virus

1979 • 80 citations

Preparative fractionation of DNA restriction fragments by reversed phase column chromatography.

1976 • 71 citations

Nucleotide sequence analysis of viable deletion mutants lacking segments of the simian virus 40 genome coding for small t antigen

1979 • 64 citations

Nucleotide sequence of the coding portion of human alpha globin messenger RNA.

1980 • 64 citations

The 3$prime; terminal sequences of human $alpha; and $beta; globin messenger RNAs: Comparison with rabbit globin messenger RNA

1976 • 61 citations

Nucleotide sequence of 3' untranslated portion of human alpha globin mRNA

1977 • 44 citations