Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Sequence-specific recognition of double helical nucleic acids by proteins.

1976 • 1,123 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

Steroid Receptors: Elements for Modulation of Eukaryotic Transcription

1976 • 688 citations

Active chromatin

1982 • 549 citations

Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids

1981 • 489 citations

Temporal order of chromatin structural changes associated with activation of the major chicken vitellogenin gene

1983 • 366 citations

Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.

1981 • 341 citations

Most of the coding region of rat ACTHβ–LPH precursor gene lacks intervening sequences

1980 • 305 citations

Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus

1981 • 303 citations

The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements

1983 • 299 citations

Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action

1975 • 284 citations

Nucleotide sequences at host–proviral junctions for mouse mammary tumour virus

1981 • 261 citations

Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA.

1977 • 256 citations

Regulatory and coding potential of the mouse mammary tumor virus long terminal redundancy

1981 • 241 citations

Purification of the glucocorticoid receptor from rat liver cytosol.

1979 • 239 citations

Genetic Approaches to Steroid Hormone Action

1976 • 203 citations

Direct demonstration of glucocorticoid receptor phosphorylation by intact L-cells.

1983 • 200 citations

Characterization of the purified activated glucocorticoid receptor from rat liver cytosol.

1984 • 186 citations

Promoters: Structure and function

1983 • 186 citations

Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promoter region

1982 • 181 citations

Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.

1982 • 178 citations

Transposon-mediated site-specific recombination: Identification of three binding sites for resolvase at the res sites of γδ and Tn 3

1982 • 155 citations

Use of polylysine for adsorption of nuclei acids and enzymes to electron microscope specimen films.

1977 • 153 citations

Glucocorticoid receptors recognize DNA sequences in and around murine mammary tumour virus DNA.

1982 • 153 citations

Purified glucocorticoid receptor-hormone complex from rat liver cytosol binds specifically to cloned mouse mammary tumor virus long terminal repeats in vitro.

1982 • 147 citations

Protein-DNA Interactions at the Origin of Simian Virus 40 DNA Replication

1979 • 127 citations

Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells.

1979 • 120 citations

Mammary tumor virus DNA contains sequences required for its hormone-regulated transcription

1981 • 120 citations

Photoaffinity labeling of glucocorticoid receptors.

1981 • 117 citations

Glucocorticoid effect on the level of corticotropin messenger RNA activity in rat pituitary.

1977 • 108 citations

[56] RNA polymerase nascent product analysis

1980 • 104 citations

Affinity labeling of the rat liver glucocorticoid receptor with dexamethasone 21-mesylate. Identification of covalently labeled receptor by immunochemical methods.

1981 • 101 citations

Multiple specific binding sites for purified glucocorticoid receptors on mammary tumor virus DNA

1982 • 90 citations

Glucocorticoids and Chromosomal Position Modulate Murine Mammary Tumor Virus Transcription by Affecting Efficiency of Promoter Utilization

1983 • 71 citations

Isolation of glucocorticoid-unresponsive rat hepatoma cells by fluorescence-activated cell sorting

1980 • 63 citations

Activation of Transcription by the Cyclic AMP Receptor Protein

1984 • 57 citations

Hormonal regulation of the conformation of the ovalbumin gene in chick oviduct chromatin.

1982 • 55 citations

Oligomeric structure of a simian virus 40 T antigen in free form and bound to DNA

1981 • 53 citations

The Effect of Steroid Hormones on Gene Transcription

1984 • 43 citations

Glucocorticoids and chromosomal position modulate murine mammary tumor virus transcription by affecting efficiency of promoter utilization.

1983 • 42 citations

Integration and Activity of Mammary Tumor Virus Genes: Regulation by Hormone Receptors and Chromosomal Position

1981 • 37 citations

Estrogen induces tissue specific changes in the chromatin conformation of the vitellogenin genes in Xenopus

1981 • 31 citations

Nuclease sensitivity and DNA methylation in estrogen regulation of Xenopus laevis vitellogenin gene expression.

1983 • 27 citations