Polycistronic Animal Virus mRNAs

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

1988 • 1,884 citations

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

1988 • 1,325 citations

Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes

1981 • 1,265 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles

1983 • 1,256 citations

Capping of eucaryotic mRNAs

1976 • 1,141 citations

Selection of AUG initiation codons differs in plants and animals.

1987 • 1,053 citations

Die Molekularbiologie der Tumorviren

1977 • 951 citations

Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

1988 • 936 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Primary structure, gene organization and polypeptide expression of poliovirus RNA

1981 • 897 citations

Nucleotide sequence and organization of the adeno-associated virus 2 genome

1983 • 716 citations

Influences of mRNA secondary structure on initiation by eukaryotic ribosomes.

1986 • 684 citations

Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eukaryotic mRNA reduces translational efficiency

1985 • 645 citations

Signals for ribosomal frameshifting in the rous sarcoma virus gag-pol region

1988 • 617 citations

Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex.

1982 • 580 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.

1983 • 568 citations

Molecular cloning of poliovirus cDNA and determination of the complete nucleotide sequence of the viral genome.

1981 • 545 citations

Effects of Intercistronic Length on the Efficiency of Reinitiation by Eucaryotic Ribosomes

1987 • 540 citations

EUKARYOTIC PROTEIN SYNTHESIS

1985 • 538 citations

Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo

1984 • 520 citations

Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells.

1984 • 502 citations

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

1988 • 481 citations

Expression of the Rous Sarcoma Virus pol Gene by Ribosomal Frameshifting

1985 • 471 citations

VIRAL PROTEINASES

1988 • 448 citations

Role of RNase H in hybrid-arrested translation by antisense oligonucleotides.

1988 • 445 citations

THE PATHWAY OF EUKARYOTIC mRNA FORMATION

1983 • 429 citations

Complete nucleotide sequences of all three poliovirus serotype genomes

1984 • 421 citations

Bifunctional messenger RNAs in eukaryotes

1986 • 405 citations

ATP-dependent unwinding of messenger RNA structure by eukaryotic initiation factors.

1985 • 404 citations

Selection of initiation sites by eucaryotic ribosomes: effect of inserting AUG triplets upstream from the coding sequence for preproinsulin

1984 • 390 citations

Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene.

1985 • 382 citations

Murine leukemia virus protease is encoded by the gag-pol gene and is synthesized through suppression of an amber termination codon.

1985 • 334 citations

Measles virus P gene codes for two proteins

1985 • 333 citations

The 2.2 kb E1b mRNA of human Ad12 and Ad5 codes for two tumor antigens starting at different AUG triplets

1981 • 290 citations

Effects of intercistronic length on the efficiency of reinitiation by eucaryotic ribosomes.

1987 • 277 citations

Cap-independent translation of poliovirus mRNA is conferred by sequence elements within the 5' noncoding region.

1988 • 273 citations

The synthesis of Sendai virus polypeptides in infected cells

1976 • 271 citations

Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation of gag and pol

1987 • 258 citations

In vitro translation of poliovirus RNA: utilization of internal initiation sites in reticulocyte lysate

1984 • 239 citations

Novel transcription map for the B19 (human) pathogenic parvovirus

1987 • 238 citations

Initiation of translation at internal AUG codons in mammalian cells

1984 • 231 citations

Sendai virus contains overlapping genes expressed from a single mRNA

1983 • 231 citations

Termination-reinitiation occurs in the translation of mammalian cell mRNAs.

1986 • 213 citations

The ATP-dependent interaction of eukaryotic initiation factors with mRNA.

1987 • 209 citations

Two efficient ribosomal frameshifting events are required for synthesis of mouse mammary tumor virus gag-related polyproteins.

1987 • 208 citations

Migration of 40 S ribosomal subunits on messenger RNA in the presence of edeine.

1978 • 201 citations

Influence of mRNA secondary structure on binding and migration of 40S ribosomal subunits

1980 • 194 citations

The protein encoded by the human proto-oncogene c-myc.

1984 • 192 citations

Comparative sequence analysis of the 5′ noncoding region of the enteroviruses and rhinoviruses

1988 • 192 citations

IMPACT OF VIRUS INFECTION ON HOST CELL PROTEIN SYNTHESIS

1987 • 188 citations

Regulation of Protein Synthesis in Virus-Infected Animal Cells

1986 • 177 citations

Ribosomal initiation from an ACG codon in the Sendai virus P/C mRNA.

1988 • 175 citations

An RNA sequence of hundreds of nucleotides at the 5' end of poliovirus RNA is involved in allowing viral protein synthesis

1988 • 173 citations

Direct mapping of adeno-associated virus capsid proteins B and C: a possible ACG initiation codon.

1985 • 173 citations

Identification of the SV40 agnogene product: a DNA binding protein

1981 • 170 citations

Synthesis of adeno-associated virus structural proteins requires both alternative mRNA splicing and alternative initiations from a single transcript

1988 • 157 citations

Regulation of Translation by Poliovirus

1987 • 152 citations

Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting

1989 • 151 citations

Role of ATP in binding and migration of 40S ribosomal subunits

1980 • 149 citations

Inability of circular mRNA to attach to eukaryotic ribosomes

1979 • 143 citations

Proteins Encoded by the Human c-myc Oncogene: Differential Expression in Neoplastic Cells

1984 • 138 citations

Mechanism of mRNA Recognition by Eukaryotic Ribosomes During Initiation of Protein Synthesis

1981 • 134 citations

A previously unrecognized influenza B virus glycoprotein from a bicistronic mRNA that also encodes the viral neuraminidase.

1983 • 131 citations

Nonsense Mutations and tRNA Suppressors

1980 • 130 citations

Internal binding of eucaryotic ribosomes on poliovirus RNA: translation in HeLa cell extracts

1989 • 130 citations

Cap-Independent Translation of Poliovirus mRNA is Conferred by Sequence Elements within the 5′ Noncoding Region

1988 • 129 citations

Effect of upstream reading frames on translation efficiency in simian virus 40 recombinants.

1986 • 125 citations

Translational efficiency of polycistronic mRNAs and their utilization to express heterologous genes in mammalian cells.

1987 • 118 citations

Mutational analysis of upstream AUG codons of poliovirus RNA

1988 • 117 citations

Spliced adenovirus-associated virus RNA.

1979 • 115 citations

Reovirus hemagglutinin mRNA codes for two polypeptides in overlapping reading frames.

1985 • 113 citations

Characterization of adenovirus-associated virus-induced polypeptides in KB cells

1978 • 113 citations

Termination-Reinitiation Occurs in the Translation of Mammalian Cell mRNAs

1986 • 109 citations

Translation in Mammalian Cells of a Gene Linked to the Poliovirus 5′ Noncoding Region

1988 • 108 citations

Molecular cloning and sequence analysis of the human parainfluenza 3 virus gene encoding the matrix protein

1987 • 108 citations

Translational control of cytomegalovirus gene expression is mediated by upstream AUG codons

1988 • 104 citations

Translational frameshifting: Where will it stop?

1987 • 103 citations

Translation of poliovirus RNA in vitro: Detection of two different initiation sites

1975 • 96 citations

Identification of the initiation site of poliovirus polyprotein synthesis

1982 • 95 citations

Translational readthrough of an amber termination codon during synthesis of feline leukemia virus protease

1985 • 90 citations

Bunyavirus Nucleoprotein, N, and a Non-structural Protein, NSS, Are Coded by Overlapping Reading Frames in the S RNA

1983 • 90 citations

Translation initiation at an ACG triplet in mammalian cells.

1987 • 90 citations

Sequences of the S1 genes of the three serotypes of reovirus.

1985 • 89 citations

An inducible mammalian amber suppressor: Propagation of a poliovirus mutant

1987 • 88 citations

ACG, the initiator codon for a Sendai virus protein.

1988 • 87 citations

Natural UAG suppressor glutamine tRNA is elevated in mouse cells infected with Moloney murine leukemia virus.

1987 • 83 citations

Biochemical evidence supporting a mechanism for cap-independent and internal initiation of eukaryotic mRNA.

1988 • 83 citations

Bovine leukemia virus protease: purification, chemical analysis, and in vitro processing of gag precursor polyproteins

1986 • 82 citations

An internal 5'-noncoding region required for translation of poliovirus RNA in vitro

1988 • 81 citations

Internal initiation of translation on the vesicular stomatitis virus phosphoprotein mRNA yields a second protein

1986 • 78 citations

Coronavirus MHV-JHM mRNA 5 Has a Sequence Arrangement which Potentially Allows Translation of a Second, Downstream Open Reading Frame

1985 • 75 citations

Binding of Ribosomes to Linear and Circular Forms of the 5′‐Terminal Leader Fragment of Tobacco‐Mosaic‐Virus RNA

1981 • 75 citations

An amber suppressor tRNA gene derived by site-specific mutagenesis: cloning and function in mammalian cells.

1982 • 71 citations

Transcripts of the adeno-associated virus genome: mapping of the major RNAs

1980 • 69 citations

HTLV-II Transactivation Is Regulated by the Overlapping tax / rex Nonstructural Genes

1988 • 68 citations

Mutation of a termination codon affects src initiation.

1984 • 68 citations

Two glycoproteins are produced from the rotavirus neutralization gene

1986 • 68 citations

Effect of mutations and deletions in a bicistronic mRNA on the synthesis of influenza B virus NB and NA glycoproteins

1989 • 67 citations

Effect of Upstream Reading Frames on Translation Efficiency in Simian Virus 40 Recombinants

1986 • 66 citations

Identification of a new polypeptide coded by reovirus gene S1

1985 • 66 citations

Messenger RNA encoding the phosphoprotein (P) gene of human parainfluenza virus 3 is bicistronic

1986 • 62 citations

Evidence that AGAUA and CCAGA initiate translation in the same mRNA in region E3 of adenovirus

1986 • 61 citations

Translational regulation of SV40 early mRNA defines a new viral protein

1987 • 61 citations

Identification and mapping of two polypeptides encoded within the herpes simplex virus type 1 thymidine kinase gene sequences

1981 • 59 citations

Biosynthesis of reovirus-specified polypeptides: The reovirus s1 mRNA encodes two primary translation products

1985 • 58 citations

In Vitro synthesis of two polypeptides from a nonstructural gene of coronavirus mouse hepatitis virus strain A59

1987 • 58 citations

Preferential stimulation of rabbit α globin mRNA translation by a cap-binding protein complex

1984 • 57 citations

Molecular cloning and sequencing of the reovirus (serotype 3) S1 gene which encodes the viral ceil attachment protein σ1

1984 • 56 citations

Ribosomal initiation at alternate AUGs on the Sendai virus P/C mRNA

1986 • 53 citations

Translational regulation of B19 parvovirus capsid protein production by multiple upstream AUG triplets.

1988 • 53 citations

Detection of a murine coronavirus nonstructural protein encoded in a downstream open reading frame

1988 • 51 citations

Utilization of internal AUG codons for initiation of protein synthesis directed by mRNAs from normal and mutant genes encoding herpes simplex virus-specified thymidine kinase

1985 • 50 citations

The P protein and the nonstructural 38K and 29K proteins of newcastle disease virus are derived from the same open reading frame

1988 • 50 citations

Effects of cDNA hybridization on translation of encephalomyocarditis virus RNA

1987 • 49 citations

Nonsense mutations and tRNA suppressors

1979 • 48 citations

Discriminatory interaction of purified eukaryotic initiation factors 4F plus 4A with the 5' ends of reovirus messenger RNAs.

1988 • 47 citations

A transcript from the S segment of the Germiston bunyavirus is uncapped and codes for the nucleoprotein and a nonstructural protein

1984 • 42 citations

Both VP2 and VP3 are synthesized from each of the alternative spliced late 19S RNA species of simian virus 40

1988 • 42 citations

Role of the avian retrovirus mRNA leader in expression: evidence for novel translational control.

1986 • 40 citations

Mutation of a Termination Codon Affects src Initiation

1984 • 40 citations

Molecular cloning and sequence analysis of the human parainfluenza 3 virus mRNA encoding the P and C proteins

1986 • 39 citations

Biosynthesis of reovirus-specified polypeptides

1977 • 37 citations

Translation initiation potential of the 5' proximal AUGs of the polycistronic P/C mRNA of Sendai virus. A multipurpose vector for site-specific mutagenesis.

1988 • 36 citations

Retroviral gag gene amber codon suppression is caused by an intrinsic cis-acting component of the viral mRNA

1988 • 34 citations

Measurement of Suppressor Transfer RNA Activity

1983 • 32 citations

Mechanisms of synthesis of virion proteins from the functionally bigenic late mRNAs of simian virus 40

1988 • 31 citations

Higher order structures of the 5'-proximal region decrease the efficiency of translation of the porcine pro-opiomelanocortin mRNA.

1988 • 31 citations

Biosynthesis of reovirus-specified polypeptides

1986 • 30 citations

A major internal initiation site for the in vitro translation of the adenovirus DNA polymerase

1986 • 30 citations

Biosynthesis of reovirus-specified polypeptides The s1 mRNA synthesized in vivo is structurally and functionally indistinguishable from in vitro-synthesized s1 mRNA and encodes two polypeptides, σ1a and σ1bNS

1985 • 30 citations

In vitro synthesis of the nonstructural C protein of Sendai virus

1983 • 30 citations

Control of reovirus messenger RNA translation efficiency by the regions upstream of initiation codons

1989 • 29 citations

Translational modulation Invitro of a eukaryotic viral mRNA encoding overlapping genes: Ribosome scanning and potential roles of conformational changes in the PC mRNA of sendai virus

1985 • 26 citations

The S segment of the Germiston virus RNA genome can code for three proteins

1987 • 26 citations

Selective inhibition of formation of suppressor glutamine tRNA in moloney murine leukemia virus-infected NIH-3T3 cells by Avarol

1988 • 25 citations

Studies on the synthesis of the influenza B virus NB glycoprotein

1984 • 24 citations

Identification of an Additional Sendai Virus Non-structural Protein Encoded by the P/C mRNA

1987 • 24 citations

Biosynthesis of reovirus-specified polypeptides: Effect of point mutation of the sequences flanking the 5′-proximal AUG initiator codons of the reovirus S1 and S4 genes on the efficiency of mRNA translation

1988 • 24 citations

Expression of five proteins from the Sendai virus P/C mRNA in infected cells

1989 • 21 citations

Translational control of synthesis of simian virus 40 late proteins from polycistronic 19S late mRNA

1988 • 19 citations

The Number of Ribosomes on Simian Virus 40 Late 16S mRNA Is Determined in Part by the Nucleotide Sequence of Its Leader

1984 • 19 citations

Secondary structure and expression in vivo and in vitro of messenger RNAs into which upstream AUG codons have been inserted

1988 • 14 citations

The number of ribosomes on simian virus 40 late 16S mRNA is determined in part by the nucleotide sequence of its leader.

1984 • 4 citations