Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

Structure of Chromatin

1977 • 1,276 citations

NUCLEASE HYPERSENSITIVE SITES IN CHROMATIN

1988 • 1,233 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

DNA bending and its relation to nucleosome positioning

1985 • 702 citations

DNA topology and its biological effects

1991 • 612 citations

Correct integration of retroviral DNA in vitro

1987 • 459 citations

DNA structural variations in the E. coli tyrT promoter

1984 • 448 citations

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter

1990 • 440 citations

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

1990 • 411 citations

Retroviral DNA integration: Structure of an integration intermediate

1988 • 397 citations

Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein.

1989 • 392 citations

A nucleoprotein complex mediates the integration of retroviral DNA.

1989 • 381 citations

A repressor (MATα2 product) and its operator control expression of a set of cell type specific genes in yeast

1985 • 368 citations

Histone Function in Transcription

1990 • 354 citations

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro

1990 • 350 citations

Retroviral DNA Integration Directed by HIV Integration Protein in Vitro

1990 • 346 citations

Structural features of a phased nucleosome core particle.

1983 • 323 citations

Specific glucocorticoid receptor binding to DNA reconstituted in a nucleosome.

1988 • 316 citations

Structure refined to 2Å of a nicked DNA octanucleotide complex with DNase I

1988 • 293 citations

Structural specificities of five commonly used DNA nucleases

1984 • 286 citations

Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains.

1991 • 269 citations

Highly preferred targets for retrovirus integration

1988 • 262 citations

Integration of human immunodeficiency virus type 1 DNA in vitro.

1990 • 257 citations

Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites

1987 • 248 citations

Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin

1986 • 212 citations

Transcriptionally active genome regions are preferred targets for retrovirus integration

1990 • 210 citations

Nucleosomes are positioned with base pair precision adjacent to the alpha 2 operator in Saccharomyces cerevisiae.

1991 • 203 citations

Nuclease digestion of circular TRP1ARS1 chromatin reveals positioned nucleosomes separated by nuclease-sensitive regions

1984 • 196 citations

Human immunodeficiency virus integration in a cell-free system

1990 • 182 citations

Irresistible force meets immovable object: Transcription and the nucleosome

1991 • 175 citations

A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an α2 dimer

1992 • 170 citations

Retroviral integration into minichromosomes in vitro.

1992 • 166 citations

Core Particle, Fiber, and Transcriptionally Active Chromatin Structure

1986 • 159 citations

Flexibility of the yeast alpha 2 repressor enables it to occupy the ends of its operator, leaving the center free.

1988 • 150 citations

Insertion Mutagenesis of Embryonal Carcinoma Cells by Retroviruses

1985 • 132 citations

Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae

1992 • 127 citations

Local protein–DNA interactions may determine nucleosome positions on yeast plasmids

1985 • 125 citations

Retroviral integration sites in transgenic Mov mice frequently map in the vicinity of transcribed DNA regions

1990 • 113 citations

Three-dimensional structure of bovine pancreatic DNase I at 2.5 A resolution.

1984 • 110 citations

Cell cycle control of higher-order chromatin assembly around naked DNA in vitro.

1991 • 103 citations

Efficient autointegration of avian retrovirus DNA in vitro

1990 • 58 citations

2 Bending of DNA in Nucleoprotein Complexes

1990 • 25 citations

Activating chromatin

1991 • 18 citations

1 New Approaches to DNA in the Crystal and in Solution

1990 • 10 citations