Integration of Signaling Networks that Regulate Dictyostelium Differentiation

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

A molecular mechanism for the effect of lithium on development.

1996 • 2,270 citations

COMMUNICATION MODULES IN BACTERIAL SIGNALING PROTEINS

1992 • 1,449 citations

A two-component system that regulates an osmosensing MAP kinase cascade in yeast

1994 • 1,091 citations

Yeast HOG1 MAP Kinase Cascade Is Regulated by a Multistep Phosphorelay Mechanism in the SLN1–YPD1–SSK1 “Two-Component” Osmosensor

1996 • 876 citations

The MADS-Box Family of Transcription Factors

1995 • 780 citations

The MADS-Box Family of Transcription Factors

1995 • 645 citations

Osmotic Activation of the HOG MAPK Pathway via Ste11p MAPKKK: Scaffold Role of Pbs2p MAPKK

1997 • 569 citations

A Member of the Frizzled Protein Family Mediating Axis Induction by Wnt-5A

1997 • 493 citations

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

1995 • 492 citations

Tagging developmental genes in Dictyostelium by restriction enzyme-mediated integration of plasmid DNA.

1992 • 484 citations

A Chemoattractant Receptor Controls Development in Dictyostelium discoideum

1988 • 465 citations

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

1999 • 444 citations

Signal Transduction via the Multi-Step Phosphorelay: Not Necessarily a Road Less Traveled

1996 • 427 citations

A ubiquitin ligase complex essential for the NF-kappa B, Wnt/Wingless, and Hedgehog signaling pathways

1999 • 427 citations

wingless signaling acts through zeste-white 3, the drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate

1992 • 425 citations

Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development.

1996 • 405 citations

Adenosine 3′,5′-Monophosphate Waves in Dictyostelium discoideum : a Demonstration by Isotope Dilution—Fluorography

1981 • 393 citations

Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum

1987 • 371 citations

Dictyostelium discoideum : a Model System for Cell-Cell Interactions in Development

1989 • 342 citations

Induction and modulation of cell-type-specific gene expression in dictyostelium

1983 • 339 citations

Cell differentiation without morphogenesis in Dictyostelium discoideum

1976 • 311 citations

Structurally distinct and stage-specific adenylyl cyclase genes play different roles in dictyostelium development

1992 • 307 citations

Similarity of sli-1 , a Regulator of Vulval Development in C. elegans , to the Mammalian Proto-Oncogene c- cbl

1995 • 298 citations

Two-component signal transducers and MAPK cascades

1997 • 288 citations

Naturally Occurring Dominant Negative Variants of Stat5

1996 • 270 citations

MOLECULAR GENETICS OF SIGNAL TRANSDUCTION IN DICTYOSTELIUM

1996 • 261 citations

Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin

1998 • 258 citations

JAK/STAT signaling by cytokine receptors

1998 • 242 citations

Protein histidine kinases and signal tranduction in prokaryotes and eukaryotes

1994 • 233 citations

SH2 Signaling in a Lower Eukaryote: A STAT Protein That Regulates Stalk Cell Differentiation in Dictyostelium

1997 • 230 citations

Glycogen synthase kinase 3 regulates cell fate in dictyostelium

1995 • 221 citations

Interacting signalling pathways regulating prestalk cell differentiation and movement during the morphogenesis of Dictyostelium.

1993 • 219 citations

Direct induction of dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen

1987 • 215 citations

Three-dimensional scroll waves organize Dictyostelium slugs.

1992 • 209 citations

Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch

1993 • 203 citations

Tyrosine Phosphorylation of the c-cbl Proto-oncogene Protein Product and Association with Epidermal Growth Factor (EGF) Receptor upon EGF Stimulation

1995 • 202 citations

Optimization and in situ detection of Escherichia coli β-galactosidase gene expression in Dictyostelium discoideum

1989 • 200 citations

Ammonia determines the choice of morphogenetic pathways in Dictyostelium discoideum

1977 • 190 citations

A Secreted Factor and Cyclic AMP Jointly Regulate Cell-Type-Specific Gene Expression in Dictyostelium discoideum

1985 • 189 citations

Cell Sorting daring Pattern Formation in Dictyostelium

1981 • 189 citations

Alternative Developmental Pathways Determined by Environmental Conditions in the Cellular Slime Mold Dictyostelium discoideum

1969 • 189 citations

Fate and regulation of anterior-like cells in Dictyostelium slugs

1982 • 188 citations

Cell-Autonomous Determination of Cell-Type Choice in Dictyostelium Development by Cell-Cycle Phase

1987 • 187 citations

An analysis of culmination in Dictyostelium using prestalk and stalk-specific cell autonomous markers

1991 • 186 citations

Cloning and characterization of cbl-b: a SH3 binding protein with homology to the c-cbl proto-oncogene.

1995 • 185 citations

A new anatomy of the prestalk zone in Dictyostelium

1989 • 183 citations

Origins of the prestalk-prespore pattern in Dictyostelium development

1989 • 179 citations

Developmental signal transduction pathways uncovered by genetic suppressors

1996 • 173 citations

CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium.

1994 • 172 citations

Regulating protein degradation by ubiquitination

1997 • 169 citations

A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium.

1995 • 166 citations

Dependence of cell-type proportioning and sorting on cell cycle phase in Dictyostelium discoideum

1984 • 162 citations

Complete sequence and transcript regulation of a cell adhesion protein from aggregating Dictyostelium cells

1986 • 158 citations

A cAMP-phosphodiesterase controls PKA-dependent differentiation

1998 • 155 citations

Molecular genetic analysis of two G alpha protein subunits in Dictyostelium.

1991 • 153 citations

An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium

1998 • 150 citations

Integration of signaling information in controlling cell-fate decisions in Dictyostelium.

1995 • 149 citations

Culmination in dictyostelium is regulated by the cAMP-dependent protein kinase

1992 • 148 citations

Two distinct populations of prestalk cells within the tip of the migratory Dictyostelium slug with differing fates at culmination

1993 • 148 citations

Gene targeting of the aggregation stage cAMP receptor cAR1 in Dictyostelium.

1991 • 148 citations

Spiral and concentric waves organize multicellular Dictyostelium mounds

1995 • 146 citations

G protein-linked signaling pathways control the developmental program of dictyostelium

1994 • 145 citations

LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium.

1994 • 144 citations

The hybrid histidine kinase DokA is part of the osmotic response system of Dictyostelium.

1996 • 141 citations

The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium

1996 • 137 citations

Cloning and cDNA sequence of the regulatory subunit of cAMP-dependent protein kinase from Dictyostelium discoideum.

1987 • 136 citations

CAR2, a prestalk cAMP receptor required for normal tip formation and late development of Dictyostelium discoideum.

1993 • 136 citations

A spatial gradient of expression of a cAMP-regulated prespore cell-type-specific gene in Dictyostelium.

1990 • 132 citations

A secreted 80 × 103M r protein mediates sensing of cell density and the onset of development in Dictyostelium

1991 • 130 citations

Evidence for positional differentiation of prestalk cells and for a morphogenetic gradient in dictyostelium

1995 • 129 citations

Mutation of protein kinase A causes heterochronic development of Dictyostelium

1992 • 128 citations

A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium

1997 • 128 citations

Cyclic AMP Regulation of Early Gene Expression in Dictyostelium discoideum: Mediation via the Cell Surface Cyclic AMP Receptor

1987 • 127 citations

A secreted factor and cyclic AMP jointly regulate cell-type-specific gene expression in Dictyostelium discoideum.

1985 • 126 citations

Combinatorial control of cell differentiation by cAMP and DIF-1 during development of Dictyostelium discoideum

1990 • 126 citations

Activation of the prespore and spore cell pathway of Dictyostelium differentiation by cAMP-dependent protein kinase and evidence for its upstream regulation by ammonia.

1993 • 126 citations

Positively and negatively acting signals regulating stalk cell and anterior-like cell differentiation in dictyostelium

1991 • 123 citations

A new class of rapidly developing mutants in Dictyostelium discoideum: Implications for cyclic AMP metabolism and cell differentiation

1983 • 121 citations

Excitation, adaption, and deadaptation of the cAMP-mediated cGMP Response in dictyostelium discoideum

1983 • 121 citations

Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium.

1994 • 117 citations

The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein

1989 • 115 citations

A two-component histidine kinase gene that functions in Dictyostelium development.

1996 • 114 citations

Analysis of optical density wave propagation and cell movement in the cellular slime mould Dictyostelium discoideum

1991 • 113 citations

Cyclic 3', 5'-AMP relay dictyostelium discoideum. V. Adaptation of the cAMP signaling response during cAMP stimulation

1980 • 113 citations

A revision of the Dictyostelium discoideum cell cycle

1984 • 113 citations

Developmentally and spatially regulated activation of a Dictyostelium STAT protein by a serpentine receptor

1998 • 111 citations

Dictyostelium mutants lacking DIF, a putative morphogen

1983 • 110 citations

Signal emission and signal propagation during early aggregation in Dictyostelium discoideum

1976 • 108 citations

Role of PKA in the Timing of Developmental Events in Dictyostelium Cells

1998 • 108 citations

DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase.

1992 • 108 citations

PSF and CMF, autocrine factors that regulate gene expression during growth and early development ofDictyostelium

1995 • 108 citations

Developmental regulation of a stalk cell differentiation-inducing factor in Dictyostelium discoideum

1982 • 104 citations

Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family.

1991 • 103 citations

The G alpha subunit G alpha 4 couples to pterin receptors and identifies a signaling pathway that is essential for multicellular development in Dictyostelium.

1994 • 102 citations

Two cAMP receptors activate common signaling pathways in Dictyostelium.

1994 • 102 citations

Evidence that elevated intracellular cyclic AMP triggers spore maturation in Dictyostelium

1989 • 102 citations

A Dictyostelium prespore-specific gene is transcriptionally repressed by DIF in vitro

1988 • 101 citations

Multiple roles for cAMP-dependent protein kinase during Dictyostelium development

1992 • 99 citations

Cyclic AMP is an inhibitor of stalk cell differentiation in Dictyostelium discoideum

1988 • 99 citations

Seven Helix Chemoattractant Receptors Transiently Stimulate Mitogen-activated Protein Kinase in Dictyostelium

1996 • 99 citations

Signal Transduction Pathways Leading to Spore Differentiation inDictyostelium discoideum

1998 • 98 citations

Identification and targeted gene disruption of cAR3, a cAMP receptor subtype expressed during multicellular stages of Dictyostelium development.

1993 • 98 citations

SDF-2 Induction of Terminal Differentiation in Dictyostelium discoideum Is Mediated by the Membrane-Spanning Sensor Kinase DhkA

1999 • 96 citations

Molecular characterization of anterior-like cells in Dictyostelium discoideum

1985 • 96 citations

The cyclic nucleotide specificity of three cAMP receptors in Dictyostelium.

1992 • 94 citations

Two-phase regulatory pathway controls cAMP receptor-mediated expression of early genes in Dictyostelium.

1989 • 93 citations

A multidrug resistance transporter/serine protease gene is required for prestalk specialization in Dictyostelium.

1995 • 93 citations

Three-dimensional waves of excitation during Dictyostelium morphogenesis.

1993 • 92 citations

Signaling through chemoattractant receptors in Dictyostelium

1996 • 92 citations

An oligosaccharide-containing factor that induces cell differentiation in Dictyostelium discoideum.

1979 • 91 citations

STAT structure and function in signaling

1998 • 91 citations

Complications and implications of linear bacterial chromosomes

1996 • 90 citations

Adenylyl Cyclase G, an Osmosensor Controlling Germination of Dictyostelium Spores

1996 • 90 citations

Structure of discadenine, a spore germination inhibitor from the cellular slime mold,

1976 • 87 citations

The Histidine KinasedhkCRegulates the Choice between Migrating Slugs and Terminal Differentiation inDictyostelium discoideum

1998 • 87 citations

Interacting signaling pathways controlling multicellular development in Dictyostelium

1996 • 87 citations

Protein aspartate phosphatases control the output of two-component signal transduction systems

1996 • 86 citations

Analysis of cell movement during the culmination phase of Dictyostelium development

1996 • 86 citations

Patterns of cell movement within the Dictyostelium slug revealed by cell type-specific, surface labeling of living cells

1994 • 84 citations

The cAMP receptor CAR4 regulates axial patterning and cellular differentiation during late development of Dictyostelium.

1994 • 83 citations

Progression of an inductive signal activates sporulation in Dictyostelium discoideum

1994 • 83 citations

Chemotactic sorting to cAMP in the multicellular stages of Dictyostelium development.

1992 • 82 citations

Role of cAMP-Dependent Protein Kinase in Controlling Aggregation and Postaggregative Development inDictyostelium

1997 • 82 citations

Purification of stalk‐cell‐inducing morphogens from Dictyostelium discoideum

1983 • 82 citations

Enhancer Regions Responsible for Temporal and Cell-Type-Specific Expression of a Spore Coat Gene in Dictyostelium

1993 • 80 citations

Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis

1999 • 80 citations

wingless acts through the shaggy/zeste-white 3 kinase to direct dorsal-ventral axis formation in the Drosophila leg

1994 • 79 citations

CELL TYPE CONVERSION IN ISOLATED PRESTALK AND PRESPORE FRAGMENTS OF THE CELLULAR SLIME MOLD DICTYOSTELIUM DISCOIDEUM

1973 • 77 citations

Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: mediation via the cell surface cyclic AMP receptor.

1987 • 76 citations

The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways.

1996 • 75 citations

Induction of terminal differentiation of Dictyostelium by cAMP-dependent protein kinase and opposing effects of intracellular and extracellular cAMP on stalk cell differentiation

1993 • 75 citations

cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development

1993 • 75 citations

Overproduction of the regulatory subunit of the cAMP-dependent protein kinase blocks the differentiation of Dictyostelium discoideum.

1989 • 74 citations

NITROGEN METABOLISM OF THE SLIME MOLD DICTYOSTELIUM DISCOIDEUM DURING GROWTH AND MORPHOGENESIS

1954 • 74 citations

Cell Type Regulation in Response to Expression of ricin A in Dictyostelium

1993 • 74 citations

The initiation of basal disc formation in Dictyostelium discoideum is an early event in culmination

1996 • 74 citations

Evidence that the RdeA protein is a component of a multistep phosphorelay modulating rate of development in Dictyostelium

1998 • 73 citations

Cellular and subcellular distribution of a cAMP-regulated prestalk protein and prespore protein in Dictyostelium discoideum: a study on the ontogeny of prestalk and prespore cells.

1986 • 73 citations

Expression of cAMP-dependent protein kinase in prespore cells is sufficient to induce spore cell differentiation in Dictyostelium.

1994 • 72 citations

Dictyostelium myosin heavy chain kinase A regulates myosin localization during growth and development.

1996 • 72 citations

Genetic networks that regulate development in Dictyostelium cells

1996 • 70 citations

Coordinate regulation of the spore coat genes in Dictyostelium discoideum

1991 • 70 citations

Functional significance of a family of protein kinases encoded at the shaggy locus in Drosophila.

1993 • 70 citations

Glycogen synthase kinase-3 (GSK-3) is regulated during Dictyostelium development via the serpentine receptor cAR3

1999 • 69 citations

Two-component signal transduction systems in eukaryotic microorganisms

1998 • 69 citations

Mitochondrial DNA replication but no nuclear DNA replication during development of Dictyostelium.

1995 • 68 citations

A study of PstB cells during Dictyostelium migration and culmination reveals a unidirectional cell type conversion process

1992 • 67 citations

Serpentine cAMP receptors may act through a G protein-independent pathway to induce postaggregative development in dictyostelium

1995 • 64 citations

A role for cAMP-dependent protein kinase A in early Dictyostelium development.

1990 • 64 citations

The surface cyclic AMP receptors, cAR1, cAR2, and cAR3, promote Ca2+ influx in Dictyostelium discoideum by a G alpha 2-independent mechanism.

1993 • 64 citations

A Novel Adenylyl Cyclase Detected in Rapidly Developing Mutants of Dictyostelium

1998 • 64 citations

cAMP‐dependent protein kinase activity is essential for preaggregative gene expression in Dictyostelium

1995 • 63 citations

cAMP signal transduction pathways regulating development of Dictyostelium discoideum

1991 • 63 citations

Switching of Chemoattractant Receptors Programs Development and Morphogenesis inDictyostelium:Receptor Subtypes Activate Common Responses at Different Agonist Concentrations

1998 • 63 citations

Cell-Cycle-Dependent Sorting in the Development of Dictyostelium Cells

1994 • 62 citations

Inhibition by ammonia of intracellular cAMP accumulation in dictyostelium discoideum: Its significance for the regulation of morphogenesis

1979 • 62 citations

Functional analysis of Wingless reveals a link between intercellular ligand transport and dorsal-cell-specific signaling

1998 • 60 citations

Identification and Functional Analysis of a Developmentally Regulated Extracellular Signal-Regulated Kinase Gene in Dictyostelium discoideum

1994 • 59 citations

Identification of CRAC, a cytosolic regulator required for guanine nucleotide stimulation of adenylyl cyclase in Dictyostelium.

1994 • 59 citations

Multiple copies of a G-rich element upstream of a cAMP-inducible Dictyostelium gene are necessary but not sufficient for efficient gene expression

1988 • 59 citations

A repressor controls the timing and spatial localisation of stalk cell-specific gene expression in Dictyostelium

1993 • 58 citations

Two transmembrane signaling mechanisms control expression of the cAMP receptor gene CAR1 during Dictyostelium development.

1993 • 58 citations

A developmentally regulated trans-acting factor recognizes dissimilar G/C-rich elements controlling a class of cAMP-inducible Dictyostelium genes.

1990 • 57 citations

Amino acid substitutions in the Dictyostelium G alpha subunit G alpha 2 produce dominant negative phenotypes and inhibit the activation of adenylyl cyclase, guanylyl cyclase, and phospholipase C.

1992 • 57 citations

Cell cycle phase in Dictyostelium discoideum is correlated with the expression of cyclic AMP production, detection, and degradation

1988 • 57 citations

The Hybrid Histidine KinasedhkBRegulates Spore Germination inDictyostelium discoideum

1998 • 56 citations

The ‘prespore-like cells’ of Dictyostelium have ceased to express a prespore gene: analysis using short-lived β-galactosidases as reporters

1994 • 55 citations

A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation

1998 • 54 citations

Dual role of cAMP duringDictyostelium development

1995 • 54 citations

Probing an adhesion mutant of Dictyostelium discoideum with cDNA clones and monoclonal antibodies indicates a specific defect in the contact site A glycoprotein

1985 • 53 citations

A New Method for Inducing Synchronous Growth of Dictyostelium discoideum Cells Using Temperature Shifts

1986 • 53 citations

The Dictyostelium Mitogen-activated Protein Kinase ERK2 Is Regulated by Ras and cAMP-dependent Protein Kinase (PKA) and Mediates PKA Function

1997 • 53 citations

Isolation of two genes encoding putative protein kinases regulated during Dictyostelium discoideum development

1991 • 51 citations

Spatial and temporal regulation of a foreign gene by a prestalk-specific promoter in transformed Dictyostelium discoideum.

1986 • 50 citations

Production and activity of spore differentiation factors (SDFs) in Dictyostelium

1998 • 50 citations

Developmental and spatial regulation of a Dictyostelium prespore gene: cis-acting elements and a cAMP-induced, developmentally regulated DNA binding activity

1991 • 50 citations

DIF-1 induces its own breakdown in Dictyostelium.

1992 • 49 citations

A new spore differentiation factor (SDF) secreted by Dictyostelium cells is phosphorylated by the cAMP dependent protein kinase

1997 • 48 citations

Mutations causing rapid development of Dictyostelium discoideum

1977 • 48 citations

Autonomous and nonautonomous regulation of axis formation by antagonistic signaling via 7-span cAMP receptors and GSK3 in Dictyostelium

1997 • 47 citations

Identification of the Cell Fate Gene Stalky in Dictyostelium

1996 • 47 citations

An 80-bp cis-acting regulatory region controls cAMP and development regulation of a prestalk gene in Dictyostelium.

1988 • 46 citations

THE EFFECT OF SALTS AND ORGANIC SOLUTES ON THE MIGRATION TIME OF THE SLIME MOLD DICTYOSTELIUM DISCOIDEUM

1952 • 46 citations

A trans-acting factor required for cAMP-induced gene expression in Dictyostelium is regulated developmentally and induced by cAMP.

1989 • 45 citations

The Role of the Cyclic Nucleotide Phosphodiesterase of Dictyostelium discoideum during Growth, Aggregation, and Morphogenesis: Overexpression and Localization Studies with the Separate Promoters of the pde

1993 • 45 citations

Regulation of cellular differentiation during dictyostelium morphogenesis

1991 • 43 citations

Dictyostelium Myosin II Is Regulated during Chemotaxis by a Novel Protein Kinase C

1996 • 43 citations

Multiple effects of differentiation-inducing factor on prespore differentiation and cyclic-AMP signal transduction in Dictyostelium

1986 • 43 citations

Dictyostelium discoideum: Cell-type proportioning, cell-differentiation preference, cell fate, and the behavior of anterior-like cells in Hs1/Hs2 and G+/G− mixtures

1986 • 42 citations

Immuno-localization and separation of multiple prestalk cell types in Dictyostelium

1992 • 41 citations

Identification and functional analysis of a developmentally regulated extracellular signal-regulated kinase gene in Dictyostelium discoideum.

1994 • 41 citations

The homeobox-containing gene Wariai regulates anterior-posterior patterning and cell-type homeostasis in Dictyostelium

1998 • 41 citations

Extracellular cAMP can restore development in Dictyostelium cells lacking one, but not two subtypes of early cAMP receptors (cARs). Evidence for involvement of cAR1 in aggregative gene expression

1994 • 41 citations

The role of cyclic gmp in regulating myosin during chemotaxis of Dictyostelium: evidence from a mutant lacking the normal cyclic gmp response to cyclic amp

1993 • 41 citations

Dual role of cAMP and involvement of both G-proteins and ras in regulation of ERK2 in Dictyostelium discoideum.

1996 • 40 citations

The cAMP Receptor Subtype cAR2 Is Restricted to a Subset of Prestalk Cells duringDictyosteliumDevelopment and Displays Unexpected DIF-1 Responsiveness

1996 • 40 citations

The cell density factor CMF regulates the chemoattractant receptor cAR1 in Dictyostelium.

1996 • 39 citations

Evidence that a combined activator-repressor protein regulates Dictyostelium stalk cell differentiation.

1996 • 39 citations

A Serum Response Factor homolog is required for spore differentiation in Dictyostelium

1998 • 38 citations

The precocious appearance and activation of an adenylate cyclase in a rapid developing mutant of Dictyostelium discoideum

1980 • 38 citations

A localized differentiation-inducing-factor sink in the front of the Dictyostelium slug.

1993 • 36 citations

Temperature-sensitive Gbeta mutants discriminate between G protein-dependent and -independent signaling mediated by serpentine receptors

1998 • 36 citations

Cyclic nucleotide phosphodiesterase of Dictyostelium discoideum and its glycoprotein inhibitor: Structure and expression of their genes

1991 • 36 citations

A G-rich sequence element common to Dictyostelium genes which differ radically in their patterns of expression

1992 • 36 citations

An unusual catalytic subunit for the cAMP-dependent protein kinase of Dictyostelium discoideum

1993 • 36 citations

Regulation by protein-tyrosine phosphatase PTP2 is distinct from that by PTP1 during Dictyostelium growth and development.

1994 • 35 citations

Multiple Roles of the Novel Protein Tyrosine Phosphatase PTP3 during Dictyostelium Growth and Development

1996 • 35 citations

A GBF-binding site and a novel AT element define the minimal sequences sufficient to direct prespore-specific expression in Dictyostelium discoideum.

1994 • 35 citations

A novel Myb homolog initiates Dictyostelium development by induction of adenylyl cyclase expression

1998 • 35 citations

cAMP-induced desensitization of surface cAMP receptors in Dictyostelium: different second messengers mediate receptor phosphorylation, loss of ligand binding, degradation of receptor, and reduction of receptor mRNA levels.

1992 • 35 citations

Morphogenesis in Dictyostelium: new twists to a not-so-old tale

1995 • 34 citations

lagC-Null andgbf-Null Cells Define Key Steps in the Morphogenesis ofDictyosteliumMounds

1998 • 34 citations

Protein kinase A is a positive regulator of spore coat gene transcription in Dictyostelium

1995 • 34 citations

Lithium respecifiescyclic ‐AMP‐lnduced cell‐type specific gene expression in Dictyostelium

1988 • 34 citations

Chemoattractant-mediated increases in cGMP induce changes in Dictyostelium myosin II heavy chain-specific protein kinase C activities.

1996 • 33 citations

The cyclic nucleotide phosphodiesterases of Dictyostelim discoideum: Molecular genetics and biochemistry

1992 • 32 citations

Pattern Formation in a Cell‐Cycle Dependent Manner during the Development of Dictyostelium discoideum

1993 • 31 citations

A Novel Component Involved in Ubiquitination Is Required for Development of Dictyostelium discoideum

1998 • 30 citations

Regulatory role of the Gα1 subunit in controlling cellular morphogenesis in Dictyostelium

1994 • 29 citations

Characterization of anterior-like cells in Dictyostelium as analyzed by their movement

1986 • 29 citations

The Regulation of Dictyostelium Development by Transmembrane Signalling

1995 • 29 citations

Cell Sorting within the Prespore Zone of Dictyostelium discoideum

1993 • 28 citations

Differential Distribution of cAMP Receptors cAR2 and cAR3 duringDictyosteliumDevelopment

1996 • 28 citations

Spalten, a protein containing Gα-protein-like and PP2C domains, is essential for cell-type differentiation in Dictyostelium

1998 • 28 citations

Symmetry Breaking inDictyosteliumMorphogenesis: Evidence That a Combination of Cell Cycle Stage and Positional Information Dictates Cell Fate

1997 • 27 citations

Regulation of myosin regulatory light chain phosphorylation via cyclic GMP during chemotaxis of Dictyostelium

1994 • 26 citations

PARASEXUAL GENETIC ANALYSIS OF CELL PROPORTIONING MUTANTS OF DICTYOSTELIUM DISCOIDEUM

1981 • 26 citations

Social senses: G-protein-coupled receptor signaling pathways in Dictyostelium discoideum

1996 • 25 citations

Functional Promiscuity of Gene Regulation by Serpentine Receptors in Dictyostelium discoideum

1998 • 25 citations

A Ubiquitin-Conjugating Enzyme Is Essential for Developmental Transitions inDictyostelium

1997 • 23 citations

Diffusible signal molecules controlling cell differentiation and patterning in Dictyostelium

1991 • 23 citations

Ammonia hypersensitivity of slugger mutants of D. discoideum

1994 • 21 citations

cAMP-Dependent Protein Kinase Is Required for the Expression of a Gene Specifically Expressed inDictyosteliumPrestalk Cells

1996 • 21 citations

Protein degradation: De-ubiquitinate to decide your fate

1996 • 21 citations

Cyclic nucleotide specificity of the activator and catalytic sites of a cGMP‐stimulated cGMP phosphodiesterase from Dictyostelium discoideum

1985 • 20 citations

rZIP, a RING-leucine zipper protein that regulates cell fate determination during Dictyostelium development

1997 • 18 citations

Regulation of the Dictyostelium cAMP-induced, prestalk-specific DdrasD gene: identification of cis-acting elements

1992 • 17 citations

Control of cell-type specific gene expression in Dictyostelium by the general transcription factor GBF

1997 • 17 citations

Delta, Notch, and shaggy: Elements of a Lateral Signaling Pathway in Drosophila

1992 • 13 citations

Non-autonomous regulation of a graded, PKA-mediated transcriptional activation signal for cell patterning

1998 • 11 citations

Sequence-specific protein interaction with a transcriptional enhancer involved in the autoregulated expression of cAMP receptor 1 in Dictyostelium

1998 • 8 citations

Extracellular signals and intracellular transduction pathways regulating Dictyostelium development

1989 • 7 citations

Adaptation of Dictyostelium Discoideum Cells to Chemotactic Signals

1987 • 5 citations

Genetic Analysis of a Gene Regulating the Timing of Developmental Events in Dictyostelium discoideum

1983 • 5 citations

Bibliography on Dictyostelium

1982 • 1 citations