Extracellular signals and intracellular transduction pathways regulating Dictyostelium development

A Chemoattractant Receptor Controls Development in Dictyostelium discoideum

1988 • 465 citations

Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain

1988 • 326 citations

Gene replacement in Dictyostelium: generation of myosin null mutants.

1989 • 299 citations

Regulation and function of Gα protein subunits in Dictyostelium

1989 • 227 citations

A new anatomy of the prestalk zone in Dictyostelium

1989 • 183 citations

Signal transduction in Dictyostelium fgd A mutants with a defective interaction between surface cAMP receptors and a GTP-binding regulatory protein [published erratum appears in J Cell Biol 1988 Dec;107(6 Pt 1):following 2463]

1988 • 124 citations

Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium.

1989 • 110 citations

Structural characterization of Dictyostelium discoideum prespore-specific gene D19 and of its product, cell surface glycoprotein PsA.

1988 • 109 citations

Evidence that elevated intracellular cyclic AMP triggers spore maturation in Dictyostelium

1989 • 102 citations

A Dictyostelium prespore-specific gene is transcriptionally repressed by DIF in vitro

1988 • 101 citations

Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum

1988 • 99 citations

Cyclic AMP is an inhibitor of stalk cell differentiation in Dictyostelium discoideum

1988 • 99 citations

Differentiation-inducing factor from the slime mould Dictyostelium discoideum and its analogues. Synthesis, structure and biological activity

1988 • 79 citations

Growing and developing Dictyostelium cells express different ras genes.

1989 • 78 citations

Overproduction of the regulatory subunit of the cAMP-dependent protein kinase blocks the differentiation of Dictyostelium discoideum.

1989 • 74 citations

Developmental consequences of the lack of myosin heavy chain in Dictyostelium discoideum

1988 • 71 citations

Cyclic AMP–phosphodiesterase induces dedifferentiation of prespore cells in Dictyostelium discoideum slugs: evidence that cyclic AMP is the morphogenetic signal for prespore differentiation

1988 • 69 citations

Hygromycin resistance as a selectable marker in Dictyostelium discoideum.

1989 • 65 citations

Multiple copies of a G-rich element upstream of a cAMP-inducible Dictyostelium gene are necessary but not sufficient for efficient gene expression

1988 • 59 citations

cAMP regulation of early gene expression in signal transduction mutants of Dictyostelium

1988 • 59 citations

Ammonia depletion and DIF trigger stalk cell differentiation in intact Dictyostelium discoideum slugs

1989 • 55 citations

Two DIF-inducible, prestalk-specific mRNAs of Dictyostelium encode extracellular matrix proteins of the slug

1988 • 54 citations

Regulatory properties of magnesium-dependent guanylate cyclase in Dictyostelium discoideum membranes

1989 • 53 citations

Signal transduction, chemotaxis, and cell aggregation in Dictyostelium discoideum cells without myosin heavy chain

1988 • 51 citations

Plasma membrane proton pump inhibition and stalk cell differentiation in Dictyostelium discoideum

1988 • 51 citations

Disruption of Dictyostelium discoideum morphogenesis by overproduction of cAMP phosphodiesterase.

1988 • 48 citations

Induction by acid load of the maturation of prestalk cells in Dictyostelium discoideum

1988 • 47 citations

An 80-bp cis-acting regulatory region controls cAMP and development regulation of a prestalk gene in Dictyostelium.

1988 • 46 citations

A trans-acting factor required for cAMP-induced gene expression in Dictyostelium is regulated developmentally and induced by cAMP.

1989 • 45 citations

Mutant RAS gene induces elevated levels of inositol tris-and hexakisphosphates in Dictyostelium

1988 • 41 citations

Localization of chemoattractant receptors on Dictyostelium discoideum cells during aggregation and down-regulation

1988 • 35 citations

An unusual protein kinase phosphorylates the chemotactic receptor of Dictyostelium discoideum.

1988 • 28 citations

Rescue of a Dictyostelium discoideum mutant defective in cyclic nucleotide phosphodiesterase

1989 • 27 citations

Agonist‐stimulated high‐affinity GTPase in Dictyostelium membranes

1988 • 25 citations

Stalk cell formation in monolayers from isolated prestalk and prespore cells of Dictyostelium discoideum: evidence for two populations of prestalk cells

1988 • 25 citations

Pertussis toxin inhibits cAMP surface receptor‐stimulated binding of [³⁵S]GTPγS to Dictyostelium discoideum membranes

1988 • 23 citations

Immunological detection of G-protein α-subunits in Dictyostelium discoideum

1988 • 18 citations

Studies on the accumulation of the differentiation-inducing factor (DIF) in high-cell-density monolayers of Dictyostelium discoideum

1989 • 16 citations

Complementation of aDictyoslelium discoideumthymidylate synthase mutation with the mouse gene provides a new selectable marker for transformation

1989 • 14 citations

Interaction between the chemotactic cAMP receptor and a detergent-insoluble membrane residue of Dictyostelium discoideum. Modulation by guanine nucleotides.

1988 • 10 citations

Endocytosis and inositol hexakisphosphate levels inras transformants ofDictyostelium discoideum amoebae

1989 • 7 citations