Overproduction of the regulatory subunit of the cAMP-dependent protein kinase blocks the differentiation of Dictyostelium discoideum.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polycrylamide to nitrocellulose

1984 • 2,553 citations

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

Growth of myxamoebae of the cellular slime mould Dictyostelium discoideum in axenic culture

1970 • 1,142 citations

Cyclic AMP and the induction of eukaryotic gene transcription.

1988 • 1,041 citations

DYNAMICS OF ANTIGENIC MEMBRANE SITES RELATING TO CELL AGGREGATION IN DICTYOSTELIUM DISCOIDEUM

1973 • 389 citations

Regulatory Mechanisms in the Control of Protein Kinase

1982 • 357 citations

Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells

1975 • 320 citations

DNA-Mediated Transformation in Dictyostelium discoideum: Regulated Expression of an Actin Gene Fusion

1984 • 277 citations

Developmental changes in messenger RNAs and protein synthesis in Dictyostelium discoideum

1977 • 267 citations

Cyclic-AMP-Controlled Oscillations in Suspended Dictyostelium Cells: Their Relation to Morphogenetic Cell Interactions

1974 • 261 citations

Chemotactic signals induce cell differentiation in Dictyostelium discoideum.

1975 • 248 citations

Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit.

1987 • 248 citations

CYCLIC AMP AND OTHER SIGNALS CONTROLLING CELL DEVELOPMENT AND DIFFERENTIATION IN DICTYOSTELIUM

1987 • 240 citations

Developmental Regulation of Dictyostelium discoideum Actin Gene Fusions Carried on Low-Copy and High-Copy Transformation Vectors

1986 • 221 citations

Molecular basis of transmembrane signal transduction in Dictyostelium discoideum

1987 • 186 citations

The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements

1988 • 186 citations

Induction of post-aggregative differentiation in Dictyostelium discoideum by cAMP

1985 • 183 citations

Recombinant Fragment of Protein Kinase Inhibitor Blocks Cyclic AMP-Dependent Gene Transcription

1987 • 139 citations

Interaction of cAMP with the cell-surface receptor induces cell-type-specific mRNA accumulation in Dictyostelium discoideum.

1986 • 139 citations

Cloning and cDNA sequence of the regulatory subunit of cAMP-dependent protein kinase from Dictyostelium discoideum.

1987 • 136 citations

Cyclic 3',5'-AMP relay in Dictyostelium discoideum III. The relationship of cAMP synthesis and secretion during the cAMP signaling response.

1980 • 111 citations

Cyclic AMP Regulation of Eukaryotic Gene Transcription by Two Discrete Molecular Mechanisms

1985 • 103 citations

Pharmacological characterization of cyclic AMP receptors mediating gene regulation in Dictyostelium discoideum.

1986 • 98 citations

Postaggregative differentiation induction by cyclic AMP in Dictyostelium: Intracellular transduction pathway and requirement for additional stimuli

1986 • 96 citations

DNA sequences required for expression of a Dictyostelium actin gene.

1986 • 94 citations

cAMP induction of prespore and prestalk gene expression in Dictyostelium is mediated by the cell-surface cAMP receptor.

1986 • 86 citations

Two vectors which facilitate gene manipulation and a simplified transformation procedure for Dictyostelium discoideum

1987 • 86 citations

A developmentally regulated cysteine proteinase in Dictyostelium discoideum.

1985 • 72 citations

Cyclic AMP levels and turnover during development of the cellular slime mold Dictyostelium discoideum

1978 • 70 citations

Genetics of early Dictyostelium discoideum development

1988 • 64 citations

A cytosolic cyclic AMP-dependent protein kinase in Dictyostelium discoideum. II. Developmental regulation.

1984 • 62 citations

A cytosolic cyclic AMP-dependent protein kinase in Dictyostelium discoideum. I. Properties.

1984 • 61 citations

cAMP regulation of early gene expression in signal transduction mutants of Dictyostelium

1988 • 59 citations

Direct evidence that the protein kinase catalytic subunit mediates the effects of cAMP on tyrosine aminotransferase synthesis.

1983 • 49 citations

Vesicle formation in Dictyostelium discoideum cells during oscillations of cAMP synthesis and release

1977 • 41 citations

Cell differentiation in the absence of intracellular cyclic AMP pulses in Dictyostelium discoideum

1981 • 30 citations

Dictyostelium discoideum mutant Synag 7 with altered g-protein–adenylate cyclase interaction

1988 • 26 citations

Detection and developmental regulation of the mRNA for the regulatory subunit of the cAMP-dependent protein kinase of D. discoideum by cell-free translation.

1986 • 26 citations

The regulatory subunit of cAMP-dependent protein kinase from Dictyostelium discoideum: cellular localization and developmental regulation analyzed by immunoblotting

1985 • 22 citations

Pharmacological Characterization of Cyclic AMP Receptors Mediating Gene Regulation in Dictyostelium discoideum

1986 • 17 citations