Diffusible signal molecules controlling cell differentiation and patterning in Dictyostelium

Disruption of the Dictyostelium Myosin Heavy Chain Gene by Homologous Recombination

1987 • 984 citations

Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans

1980 • 567 citations

The acrasin activity of adenosine-3',5'-cyclic phosphate.

1967 • 494 citations

A Chemoattractant Receptor Controls Development in Dictyostelium discoideum

1988 • 465 citations

Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum

1987 • 371 citations

Induction and modulation of cell-type-specific gene expression in dictyostelium

1983 • 339 citations

Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells

1975 • 320 citations

Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila

1990 • 316 citations

Cell differentiation without morphogenesis in Dictyostelium discoideum

1976 • 311 citations

Regulation of dictyostelium discoideum mRNAs specific for prespore or prestalk cells

1983 • 252 citations

Chemotactic signals induce cell differentiation in Dictyostelium discoideum.

1975 • 248 citations

CYCLIC AMP AND OTHER SIGNALS CONTROLLING CELL DEVELOPMENT AND DIFFERENTIATION IN DICTYOSTELIUM

1987 • 240 citations

Direct induction of dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen

1987 • 215 citations

Intracellular pH and the control of cell differentiation in Dictyostelium discoideum

1983 • 214 citations

Ammonia determines the choice of morphogenetic pathways in Dictyostelium discoideum

1977 • 190 citations

Cell Sorting daring Pattern Formation in Dictyostelium

1981 • 189 citations

Fate and regulation of anterior-like cells in Dictyostelium slugs

1982 • 188 citations

Cell-Autonomous Determination of Cell-Type Choice in Dictyostelium Development by Cell-Cycle Phase

1987 • 187 citations

A new anatomy of the prestalk zone in Dictyostelium

1989 • 183 citations

A possible morphogen controlling differentiation in Dictyostelium

1983 • 180 citations

Origins of the prestalk-prespore pattern in Dictyostelium development

1989 • 179 citations

A DESCRIPTIVE STUDY OF THE DEVELOPMENT OF THE SLIME MOLD DICTYOSTELIUM DISCOIDEUM

1944 • 158 citations

Origin of cells giving rise to mesoderm and endoderm in chick embryo

1990 • 146 citations

G protein linked signal transduction pathways in development: Dictyostelium as an experimental system

1989 • 144 citations

A Theory of the Control of Differentiation in the Cellular Slime Molds

1957 • 126 citations

Combinatorial control of cell differentiation by cAMP and DIF-1 during development of Dictyostelium discoideum

1990 • 126 citations

Interactions between adenosine and oscillatory cAMP signaling regulate size and pattern in Dictyostelium

1986 • 123 citations

Requirement for cell differentiation in Dictyostelium discoideum

1978 • 118 citations

Dictyostelium mutants lacking DIF, a putative morphogen

1983 • 110 citations

The role of cyclic nucleotides and cell agglomeration in postaggregative enzyme synthesis in Dictyostelium discoideum

1978 • 109 citations

Developmental regulation of a stalk cell differentiation-inducing factor in Dictyostelium discoideum

1982 • 104 citations

A Dictyostelium prespore-specific gene is transcriptionally repressed by DIF in vitro

1988 • 101 citations

A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis.

1989 • 100 citations

Independent regulation of the extracellular cyclic AMP phosphodiesterase-inhibitor system and membrane differentiation by exogenous cyclic AMP in Dictyostelium discoideum

1978 • 99 citations

Cyclic AMP Phosphodiesterase and its Inhibitor in Slime Mould Development

1972 • 94 citations

Nature and distribution of the morphogen DIF in the Dictyostelium slug

1987 • 93 citations

Purification of stalk‐cell‐inducing morphogens from Dictyostelium discoideum

1983 • 82 citations

Ultrastructural Development of Stalk-producing Cells in Dictyostelium discoideum, a Cellular Slime Mould

1972 • 76 citations

Inositol 1,4,5-trisphosphate induces cyclic GMP formation in Dictyosteliumdiscoideum

1985 • 74 citations

Morphogen hunting in Dictyostelium

1989 • 71 citations

Cyclic AMP levels and turnover during development of the cellular slime mold Dictyostelium discoideum

1978 • 70 citations

Cyclic AMP–phosphodiesterase induces dedifferentiation of prespore cells in Dictyostelium discoideum slugs: evidence that cyclic AMP is the morphogenetic signal for prespore differentiation

1988 • 69 citations

A specific DIF binding protein in Dictyostelium.

1990 • 63 citations

The effect of cyclic AMP on morphogenesis and enzyme accumulation in Dictyostelium discoideum

1972 • 63 citations

Control of phototactic migration in Dictyostelium discoideum

1973 • 63 citations

Identification of inositol hexaphosphate in 31P-NMR spectra of Dictyostelium discoideum amoebae. Relevance to intracellular pH determination

1987 • 61 citations

The induction of stalk cell differentiation in submerged monolayers of Dictyostelium discoideum

1984 • 61 citations

The ultrastructure of cells and cellulose membranes in Acrasiae

1959 • 57 citations

Ammonia depletion and DIF trigger stalk cell differentiation in intact Dictyostelium discoideum slugs

1989 • 55 citations

Analysis of proportion regulation in slugs of Dictyostelium discoideum using a monoclonal antibody and a FACS-IV

1983 • 50 citations

Disruption of Dictyostelium discoideum morphogenesis by overproduction of cAMP phosphodiesterase.

1988 • 48 citations

Induction by acid load of the maturation of prestalk cells in Dictyostelium discoideum

1988 • 47 citations

Patterns of cell differentiation revealed by l-[3H]fucose incorporation in Dictyostelium

1978 • 45 citations

Selective induction of stalk-cell-specific proteins in Dictyostelium

1985 • 42 citations

ATP, trehalose, glucose and ammonium ion localization in the two cell types of Dictyostelium discoideum

1978 • 40 citations

Cytoplasmic acidification facilitates but does not mediate DIF-induced prestalk gene expression in Dictyostelium discoideum

1990 • 37 citations

Differentiation of Dictyostelium discoideum in monolayer cultures and its modification by ionic conditions

1984 • 37 citations

Disruption of multicellular organization in the cellular slime molds by cyclic amp

1977 • 29 citations

Correlations between tip dominance, prestalk/prespore pattern, and CAMP-relay efficiency in slugs of Dictyostelium discoideum

1985 • 28 citations

Localization and levels of cyclic AMP during development of Dictyostelium discoideum

1984 • 28 citations

Signals controlling cell differentiation and pattern formation in Dictyostelium

1988 • 23 citations

The cyclic nucleotide phosphodiesterase of Dictyostelium discoideum: The structure of the gene and its regulation and role in development

1988 • 16 citations

The presence and location of sporopollenin in fruiting bodies of the cellular slime moulds

1984 • 11 citations

Position-Dependent regulation of the prestalk-prespore pattern inDictyostelium slugs

1990 • 7 citations