Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium.

Basic local alignment search tool

1990 • 87,358 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Basic Local Alignment Search Tool

1990 • 12,947 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

TRANSCRIPTION FACTORS: Structural Families and Principles of DNA Recognition

1992 • 1,411 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: Results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes

1980 • 1,256 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles

1983 • 1,256 citations

Codon catalog usage is a genome strategy modulated for gene expressivity

1981 • 951 citations

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase.

1992 • 453 citations

opa: A novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster

1985 • 404 citations

Different activation domains stimulate transcription from remote (‘enhancer’) and proximal (‘promoter’) positions.

1992 • 359 citations

Induction and modulation of cell-type-specific gene expression in dictyostelium

1983 • 339 citations

Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells

1975 • 320 citations

Structurally distinct and stage-specific adenylyl cyclase genes play different roles in dictyostelium development

1992 • 307 citations

Developmental regulation of a dictyostelium gene encoding a protein homologous to mammalian ras protein

1984 • 267 citations

Chapter 4 Molecular Biology in Dictyostelium: Tools and Applications

1987 • 223 citations

Developmental Regulation of Dictyostelium discoideum Actin Gene Fusions Carried on Low-Copy and High-Copy Transformation Vectors

1986 • 221 citations

Direct induction of dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen

1987 • 215 citations

A Secreted Factor and Cyclic AMP Jointly Regulate Cell-Type-Specific Gene Expression in Dictyostelium discoideum

1985 • 189 citations

An analysis of culmination in Dictyostelium using prestalk and stalk-specific cell autonomous markers

1991 • 186 citations

Induction of post-aggregative differentiation in Dictyostelium discoideum by cAMP

1985 • 183 citations

Molecular complementation of a genetic marker in Dictyostelium using a genomic DNA library.

1989 • 171 citations

Two distinct classes of prestalk-enriched mRNA sequences inDictyostelium discoideum

1987 • 169 citations

Two distinct populations of prestalk cells within the tip of the migratory Dictyostelium slug with differing fates at culmination

1993 • 148 citations

Gene targeting of the aggregation stage cAMP receptor cAR1 in Dictyostelium.

1991 • 148 citations

Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells.

1990 • 146 citations

Attractant-induced changes and oscillations of the extracellular Ca++ concentration in suspensions of differentiating Dictyostelium cells.

1984 • 143 citations

Analysis of G alpha 4, a G-protein subunit required for multicellular development in Dictyostelium.

1992 • 141 citations

Interaction of cAMP with the cell-surface receptor induces cell-type-specific mRNA accumulation in Dictyostelium discoideum.

1986 • 139 citations

CAR2, a prestalk cAMP receptor required for normal tip formation and late development of Dictyostelium discoideum.

1993 • 136 citations

A spatial gradient of expression of a cAMP-regulated prespore cell-type-specific gene in Dictyostelium.

1990 • 132 citations

A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium

1991 • 129 citations

Cyclic AMP Regulation of Early Gene Expression in Dictyostelium discoideum: Mediation via the Cell Surface Cyclic AMP Receptor

1987 • 127 citations

Combinatorial control of cell differentiation by cAMP and DIF-1 during development of Dictyostelium discoideum

1990 • 126 citations

Positively and negatively acting signals regulating stalk cell and anterior-like cell differentiation in dictyostelium

1991 • 123 citations

[2] Purification of sequence-specific binding proteins by DNA affinity chromatography

1991 • 120 citations

Characterization of two highly diverged but developmentally co-regulated cysteine proteinase genes inDictyostelium discoideum

1985 • 106 citations

Identification and targeted gene disruption of cAR3, a cAMP receptor subtype expressed during multicellular stages of Dictyostelium development.

1993 • 98 citations

Pharmacological characterization of cyclic AMP receptors mediating gene regulation in Dictyostelium discoideum.

1986 • 98 citations

Postaggregative differentiation induction by cyclic AMP in Dictyostelium: Intracellular transduction pathway and requirement for additional stimuli

1986 • 96 citations

cAMP and cell sorting control the spatial expression of a developmentally essential cell-type-specific ras gene in Dictyostelium.

1991 • 90 citations

cAMP induction of prespore and prestalk gene expression in Dictyostelium is mediated by the cell-surface cAMP receptor.

1986 • 86 citations

Identification of a DNA sequence element required for efficient expression of a developmentally regulated and cAMP-inducible gene of Dictyostelium discoideum

1987 • 80 citations

Enhancer Regions Responsible for Temporal and Cell-Type-Specific Expression of a Spore Coat Gene in Dictyostelium

1993 • 80 citations

cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development

1993 • 75 citations

Identification of the sequences controlling cyclic AMP regulation and cell-type-specific expression of a prestalk-specific gene in Dictyostelium discoideum.

1987 • 74 citations

Cellular and subcellular distribution of a cAMP-regulated prestalk protein and prespore protein in Dictyostelium discoideum: a study on the ontogeny of prestalk and prespore cells.

1986 • 73 citations

Coordinate regulation of the spore coat genes in Dictyostelium discoideum

1991 • 70 citations

cAMP signal transduction pathways regulating development of Dictyostelium discoideum

1991 • 63 citations

Multiple copies of a G-rich element upstream of a cAMP-inducible Dictyostelium gene are necessary but not sufficient for efficient gene expression

1988 • 59 citations

[25] Analysis of histone subtypes and their modified forms by polyacrylamide gel electrophoresis

1989 • 59 citations

A developmentally regulated trans-acting factor recognizes dissimilar G/C-rich elements controlling a class of cAMP-inducible Dictyostelium genes.

1990 • 57 citations

Isolation of two genes encoding putative protein kinases regulated during Dictyostelium discoideum development

1991 • 51 citations

Developmental and spatial regulation of a Dictyostelium prespore gene: cis-acting elements and a cAMP-induced, developmentally regulated DNA binding activity

1991 • 50 citations

An 80-bp cis-acting regulatory region controls cAMP and development regulation of a prestalk gene in Dictyostelium.

1988 • 46 citations

A trans-acting factor required for cAMP-induced gene expression in Dictyostelium is regulated developmentally and induced by cAMP.

1989 • 45 citations

Nucleotide sequences of Dictyostelium discoideum developmentally regulated cDNAs rich in (AAC) imply proteins that contain clusters of asparagine, glutamine, or threonine

1989 • 44 citations

Regulation of cellular differentiation during dictyostelium morphogenesis

1991 • 43 citations

Physical mapping of genes to specific chromosomes in Dictyostelium discoideum

1992 • 40 citations

Ca+ + antagonists distinguish different requirements for cAMP-mediated gene expression in the cellular slime mold, Dictyostelium discoideum

1989 • 37 citations

A G-rich sequence element common to Dictyostelium genes which differ radically in their patterns of expression

1992 • 36 citations

Microsequence Analysis of Proteins Purified by Gel Electrophoresis

1991 • 29 citations

Characterization of a novel Dictyostelium discoideum prespore-specific gene, PspB, reveals conserved regulatory sequences

1994 • 29 citations

Analysis of the Maturation Process of Prestalk Cells in Dictyostelium discoideum

1993 • 27 citations

Identification of a signal transduction response sequence element necessary for induction of a Dictyostelium discoideum gene by extracellular cyclic AMP.

1989 • 25 citations

A Pharmacologically Distinct Cyclic AMP Receptor Is Responsible for the Regulation of gp80 Expression in Dictyostelium discoideum

1990 • 22 citations

A Ca²⁺‐dependent signal transduction system participates in coupling expression of some cAMP‐dependent prespore genes to the cell surface receptor

1988 • 22 citations

Cloning, structural analysis, and expression of the glycogen phosphorylase-2 gene in Dictyostelium.

1992 • 18 citations

Regulation of the Dictyostelium cAMP-induced, prestalk-specific DdrasD gene: identification of cis-acting elements

1992 • 17 citations

A Molecular Analysis of G Proteins and Control of Early Gene Expression by the Cell-surface cAMP Receptor in Dictyostelium

1988 • 16 citations

A negative transcriptional control region of a developmentally-regulated genè co-localizes with the origin of replication of an endogenous plasmid in Dictyostelium

1992 • 9 citations

Signal transduction pathways involved in the expression of the uridine diphosphoglucose pyrophosphorylase gene of Dictyostelium discoideum

1991 • 5 citations