Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

1997 • 2,205 citations

Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1

1999 • 1,392 citations

Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination

1999 • 956 citations

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

1994 • 766 citations

Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.

1992 • 667 citations

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

2000 • 641 citations

Jagged: A mammalian ligand that activates notch1

1995 • 617 citations

An Activated Form of Notch Influences the Choice between CD4 and CD8 T Cell Lineages

1996 • 488 citations

Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta

1995 • 458 citations

The Notch Ligand Jagged-1 Represents a Novel Growth Factor of Human Hematopoietic Stem Cells

2000 • 432 citations

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice

1998 • 409 citations

Notch Activity Influences the αβ versus γδ T Cell Lineage Decision

1997 • 399 citations

Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo

1997 • 380 citations

Development of human T and natural killer cells

1995 • 379 citations

Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway

1996 • 372 citations

The Notch Ligand, Jagged-1, Influences the Development of Primitive Hematopoietic Precursor Cells

1998 • 328 citations

Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation

1998 • 328 citations

Notch1 Signaling Promotes the Maturation of CD4 and CD8 SP Thymocytes

2000 • 317 citations

Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts

1999 • 304 citations

Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development

2001 • 300 citations

The Human Homolog of Rat Jagged1Expressed by Marrow Stroma Inhibits Differentiation of 32D Cells through Interaction with Notch1

1998 • 282 citations

Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

1997 • 279 citations

Notch as a Mediator of Cell Fate Determination in Hematopoiesis: Evidence and Speculation

1999 • 265 citations

Notch Inhibition of E47 Supports the Existence of a Novel Signaling Pathway

1998 • 261 citations

Jagged2: A Serrate-like Gene Expressed during Rat Embryogenesis

1996 • 243 citations

Notch1-Induced Delay of Human Hematopoietic Progenitor Cell Differentiation Is Associated With Altered Cell Cycle Kinetics

1999 • 236 citations

Isolation and Functional Analysis of a cDNA for Human Jagged2, a Gene Encoding a Ligand for the Notch1 Receptor

1997 • 192 citations

Separation of Notch1 Promoted Lineage Commitment and Expansion/Transformation in Developing T Cells

2001 • 182 citations

Human Ligands of the Notch Receptor

1999 • 182 citations

Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells

2001 • 169 citations

Stromal Expression of Jagged 1 Promotes Colony Formation by Fetal Hematopoietic Progenitor Cells

1998 • 150 citations

Cell Cycle Arrest and Apoptosis Induced by Notch1 in B Cells

2000 • 146 citations

Notch and the Immune System

1999 • 141 citations

A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells

2000 • 137 citations

Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1

2000 • 134 citations

Targeting of U2AF65 to Sites of Active Splicing in the Nucleus

1997 • 124 citations

Notch signalling via RBP-J promotes myeloid differentiation

2000 • 122 citations

The Notch/Jagged Pathway Inhibits Proliferation of Human Hematopoietic Progenitors In Vitro

1999 • 120 citations

Long-term culture system for selective growth of human B-cell progenitors.

1995 • 82 citations

Stepwise specification of lymphocyte developmental lineages

2000 • 81 citations

Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact

2000 • 80 citations

Genetic Modification of Human B-Cell Development: B-Cell Development Is Inhibited by the Dominant Negative Helix Loop Helix Factor Id3

1999 • 77 citations

Fetal liver contains committed NK progenitors, but is not a site for development of CD34+ cells into T cells.

1997 • 76 citations

Enrichment of an Antigen-Specific T Cell Response by Retrovirally Transduced Human Dendritic Cells

1999 • 71 citations

Microenvironmental influences on human B‐cell development

2000 • 56 citations

Distinct Mechanisms Contribute to Generate and Change the CD4:CD8 Cell Ratio During Thymus Development: A Role for the Notch Ligand, Jagged1

2001 • 46 citations

Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells

2001 • 34 citations

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients.

2001 • 22 citations