Integration of Notch 1 and Calcineurin/NFAT Signaling Pathways in Keratinocyte Growth and Differentiation Control

Network biology: understanding the cell's functional organization

2004 • 7,596 citations

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

CNS stem cells express a new class of intermediate filament protein

1990 • 3,138 citations

NFAT Signaling

2002 • 1,316 citations

A Comprehensive Guide for the Accurate Classification of Murine Hair Follicles in Distinct Hair Cycle Stages

2001 • 1,246 citations

HES and HERP families: Multiple effectors of the notch signaling pathway

2003 • 1,207 citations

Cyclosporine induces cancer progression by a cell-autonomous mechanism

1999 • 1,119 citations

Notch1 functions as a tumor suppressor in mouse skin

2003 • 957 citations

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

2001 • 849 citations

Risk of Malignancies in Psoriasis Patients Treated with Cyclosporine: a 5 y Cohort Study

2003 • 374 citations

Nestin expression in hair follicle sheath progenitor cells

2003 • 348 citations

Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

1995 • 338 citations

Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling

2003 • 311 citations

γ-Secretase Functions through Notch Signaling to Maintain Skin Appendages but Is Not Required for Their Patterning or Initial Morphogenesis

2004 • 305 citations

Cathepsin L deficiency as molecular defect offurless:hyperproliferation of keratinocytes and pertubation of hair follicle cycling

2000 • 302 citations

Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling

2003 • 270 citations

Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation

2002 • 259 citations

Calcineurin as a Multifunctional Regulator

2002 • 224 citations

Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis

2000 • 216 citations

Calcineurin B1 Is Essential for Positive but Not Negative Selection during Thymocyte Development

2004 • 216 citations

Ca2+-dependent Gene Expression Mediated by MEF2 Transcription Factors

2000 • 196 citations

High Commitment of Embryonic Keratinocytes to Terminal Differentiation through a Notch1-caspase 3 Regulatory Mechanism

2004 • 182 citations

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

1999 • 179 citations

The Role of Modulatory Calcineurin-Interacting Proteins in Calcineurin Signaling

2003 • 176 citations

Desmoglein 3 anchors telogen hair in the follicle

1998 • 157 citations

Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21 ^WAF1/CIP1 expression in keratinocyte differentiation

2001 • 156 citations

Altered Skeletal Muscle Phenotypes in Calcineurin Aα and Aβ Gene-Targeted Mice

2003 • 156 citations

Localization of Calcineurin/NFAT in Human Skin and Psoriasis and Inhibition of Calcineurin/NFAT Activation in Human Keratinocytes by Cyclosporin A

2002 • 149 citations

Notch/RBP-J Signaling Regulates Epidermis/Hair Fate Determination of Hair Follicular Stem Cells

2003 • 145 citations

Dual Roles for the Notch Target Gene Hes-1 in the Differentiation of 3T3-L1 Preadipocytes

2004 • 141 citations

Involvement of the Sp3 Transcription Factor in Induction of p21 in Keratinocyte Differentiation

1997 • 134 citations

Collagen VI deficiency affects the organization of fibronectin in the extracellular matrix of cultured fibroblasts

2001 • 128 citations

Soluble Jagged 1 Represses the Function of Its Transmembrane Form to Induce the Formation of the Src-dependent Chord-like Phenotype

2001 • 120 citations

Signal Transduction Pathways Controlling the Switch Between Keratinocyte Growth and Differentiation

1999 • 106 citations

Cyclosporin A-induced hair growth in mice is associated with inhibition of calcineurin-dependent activation of NFAT in follicular keratinocytes

2003 • 63 citations

Repression of Activator Protein-1-mediated Transcriptional Activation by the Notch-1 Intracellular Domain

2002 • 47 citations

In utero activation of K5.CrePR1 induces gene deletion

2002 • 36 citations

Syndecan-4 Regulates ATF-2 Transcriptional Activity in a Rac1-dependent Manner

2004 • 31 citations

Characterization and expression of murine PRELP

2001 • 17 citations