Ca2+-dependent Gene Expression Mediated by MEF2 Transcription Factors

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

1998 • 2,570 citations

CREB Phosphorylation and Dephosphorylation: A Ca2+- and Stimulus Duration–Dependent Switch for Hippocampal Gene Expression

1996 • 1,109 citations

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type

1998 • 998 citations

JNK is involved in signal integration during costimulation of T lymphocytes

1994 • 929 citations

The Ets family of transcription factors

1993 • 848 citations

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

1995 • 817 citations

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

1997 • 770 citations

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity.

1994 • 718 citations

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene

1988 • 661 citations

SIGNAL TRANSMISSION BETWEEN THE PLASMA MEMBRANE AND NUCLEUS OF T LYMPHOCYTES

1994 • 634 citations

NF-AT components define a family of transcription factors targeted in T-cell activation

1994 • 573 citations

A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily.

1988 • 532 citations

Nuclear factor of activated T cells contains Fos and Jun

1992 • 495 citations

Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors.

1992 • 491 citations

The serum response element

1992 • 458 citations

Human SRF-related proteins: DNA-binding properties and potential regulatory targets.

1991 • 446 citations

Regulation of the MEF2 Family of Transcription Factors by p38

1999 • 429 citations

CBP: A Signal-Regulated Transcriptional Coactivator Controlled by Nuclear Calcium and CaM Kinase IV

1998 • 420 citations

Journey to the surface of the cell: Fos regulation and the SRE.

1995 • 376 citations

Molecular Mechanisms of Myogenic Coactivation by p300: Direct Interaction with the Activation Domain of MyoD and with the MADS Box of MEF2C

1997 • 363 citations

The PH084 Gene of Saccharomyces cerevisiae Encodes an Inorganic Phosphate Transporter

1991 • 350 citations

Regulation of Muscle Differentiation by the MEF2 Family of MADS Box Transcription Factors

1995 • 348 citations

A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone

1987 • 347 citations

Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis

1997 • 315 citations

A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

1995 • 305 citations

Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors.

1993 • 267 citations

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors.

1993 • 234 citations

MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex.

1993 • 234 citations

A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage

1993 • 224 citations

Activation of the Myogenic Lineage by MEF2A, a Factor that Induces and Cooperates with MyoD

1994 • 223 citations

A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing.

1994 • 218 citations

Regulation of the Nur77 Orphan Steroid Receptor in Activation-Induced Apoptosis

1995 • 216 citations

Nuclear Factor of Activated T Cells (NFAT)-dependent Transactivation Regulated by the Coactivators p300/CREB-binding Protein (CBP)

1998 • 193 citations

Regulatory Role of MEF2D in Serum Induction of the c-jun Promoter

1995 • 176 citations

NFATc3, a Lymphoid-specific NFATc Family Member That Is Calcium-regulated and Exhibits Distinct DNA Binding Specificity

1995 • 168 citations

The NGFI-B gene, a transcriptionally inducible member of the steroid receptor gene superfamily: genomic structure and expression in rat brain after seizure induction.

1989 • 167 citations

Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells.

1996 • 161 citations

Roles of calmodulin-dependent protein kinases and phosphatase in calcium-dependent transcription of immediate early genes.

1994 • 141 citations

Cyclosporin A-sensitive induction of the Epstein-Barr virus lytic switch is mediated via a novel pathway involving a MEF2 family member

1997 • 140 citations

The NGFI-B protein, an inducible member of the thyroid/steroid receptor family, is rapidly modified posttranslationally.

1990 • 139 citations

Cloning and characterization of molecular isoforms of the catalytic subunit of calcineurin using nonisotopic methods.

1990 • 130 citations

lnterleukin-2 transcriptional block by multifunctional Ca2+/ calmodulin kinase

1994 • 115 citations

A Unique Phosphorylation-dependent Mechanism for the Activation of Ca2+/Calmodulin-dependent Protein Kinase Type IV/GR

1996 • 112 citations

Expression of a Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, in human T lymphocytes. Regulation of kinase activity by T cell receptor signaling.

1993 • 93 citations

Cloning and analysis of two new isoforms of multifunctional Ca2+/calmodulin-dependent protein kinase. Expression in multiple human tissues.

1993 • 92 citations

Cooperative Transcriptional Activation by the Neurogenic Basic Helix-Loop-Helix Protein MASH1 and Members of the Myocyte Enhancer Factor-2 (MEF2) Family

1996 • 77 citations

Activation protein 1-dependent transcriptional activation of interleukin 2 gene by Ca2+/calmodulin kinase type IV/Gr.

1996 • 60 citations

Characterization of the ZI domains in the Epstein-Barr virus BZLF1 gene promoter: role in phorbol ester induction

1996 • 54 citations

Signaling from G Protein-coupled Receptors to the c-jun Promoter Involves the MEF2 Transcription Factor

1997 • 53 citations

T Cell Priming Enhances IL-4 Gene Expression by Increasing Nuclear Factor of Activated T Cells

1999 • 50 citations

Functional and Physical Interactions between Mammalian Achaete-Scute Homolog 1 and Myocyte Enhancer Factor 2A

1996 • 45 citations

The Epstein-Barr virus-induced Ca2+/calmodulin-dependent kinase type IV/Gr promotes a Ca(2+)-dependent switch from latency to viral replication

1997 • 35 citations

Cyclosporin A and FK506 Block Induction of the Epstein-Barr Virus Lyric Cycle by Anti-Immunoglobulin

1995 • 26 citations