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Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21 WAF1/CIP1 expression in keratinocyte differentiation

Data up to Jan 2025

Published2001
Citations156
References42

Total Citations Per Year

Abstract

References (42)

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism.

1995 • 938 citations

Regulation of the Calmodulin-stimulated Protein Phosphatase, Calcineurin

1998 • 892 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

The Mechanism of Action of Cyclosporin A and FK506

1996 • 664 citations

IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1

1999 • 651 citations

NF-AT components define a family of transcription factors targeted in T-cell activation

1994 • 573 citations

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation.

1994 • 531 citations

Identification of a major keratinocyte cell envelope protein, loricrin

1990 • 420 citations

Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

1995 • 338 citations

The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

1996 • 323 citations

Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1.

1993 • 310 citations

Cell Cycle-Regulated Association of E2F1 and Sp1 Is Related to Their Functional Interaction

1996 • 268 citations

Tyrosine Phosphorylation and Src Family Kinases Control Keratinocyte Cell–Cell Adhesion

1998 • 254 citations

Calcineurin Activity Is Required for the Initiation of Skeletal Muscle Differentiation

2000 • 231 citations

Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis

2000 • 216 citations

Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression.

1995 • 212 citations

c-Jun Transactivates the Promoter of the Human p21 Gene by Acting as a Superactivator of the Ubiquitous Transcription Factor Sp1

1999 • 191 citations

Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies.

1984 • 186 citations

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

1999 • 179 citations

NFATc3, a Lymphoid-specific NFATc Family Member That Is Calcium-regulated and Exhibits Distinct DNA Binding Specificity

1995 • 168 citations

Functional Interference of Sp1 and NF-κB through the Same DNA Binding Site

1998 • 160 citations

Calcium-induced assembly of adherens junctions in keratinocytes.

1987 • 159 citations

Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor.

1999 • 148 citations

Involvement of the Sp3 Transcription Factor in Induction of p21 in Keratinocyte Differentiation

1997 • 134 citations

Distinct Subdomains of Human TAFII130 Are Required for Interactions with Glutamine-Rich Transcriptional Activators

1998 • 131 citations

fyn tyrosine kinase is involved in keratinocyte differentiation control.

1995 • 113 citations

Signal Transduction Pathways Controlling the Switch Between Keratinocyte Growth and Differentiation

1999 • 106 citations

The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation

1994 • 105 citations

The gene for mouse epidermal filaggrin precursor. Its partial characterization, expression, and sequence of a repeating filaggrin unit.

1987 • 97 citations

The Proximal Promoter of the Mouse Loricrin Gene Contains a Functional AP-1 Element and Directs Keratinocyte-specific but Not Differentiation-specific Expression

1995 • 92 citations

FK-506 and cyclosporin A : immunosuppressive mechanism of action and beyond

1992 • 81 citations

Stimulation of Hair Growth by Topical Application of FK506, a Potent Immunosuppressive Agent

1994 • 56 citations

Cyclosporin A stimulates hair growth in nude mice.

1987 • 54 citations

Suspension-Induced Murine Keratinocyte Differentiation Is Mediated by Calcium

1996 • 49 citations

Extracellular calcium‐dependent regulation of transmembrane calcium fluxes in murine keratinocytes

1991 • 36 citations

[Cyclosporin A in the therapy of inflammatory dermatoses].

1992 • 26 citations

13 Cascade activation of the calmodulin kinase family

1997 • 13 citations

Signalling mechanisms and the role of calcineurin in erythropoiesis

1999 • 10 citations

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Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21 WAF1/CIP1 expression in… (2001) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer