Cyclosporine induces cancer progression by a cell-autonomous mechanism

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Cyclosporine

1989 • 1,340 citations

Cellular tumorigenicity in nude mice: Correlation with cell growth in semi-solid medium

1974 • 814 citations

TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice

1996 • 619 citations

Established cell line of urinary bladder carcinoma (T24) containing tumour‐specific antigen

1973 • 514 citations

Renal Transplantation

1994 • 428 citations

A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance.

1990 • 409 citations

Risk of neoplasia in renal transplant patients

1995 • 399 citations

Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential.

1990 • 398 citations

Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer progression.

1993 • 356 citations

Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification.

1989 • 307 citations

CANCERS FOLLOWING CYCLOSPORINS THERAPY

1987 • 255 citations

Accelerated growth rates of recurrent hepatocellular carcinoma after liver transplantation

1991 • 251 citations

Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction.

1991 • 206 citations

Establishment of a cloned line of Lewis lung carcinoma cells adapted to cell culture

1980 • 205 citations

Transforming growth factor β stimulates mamary adenocarcinoma cell invasion and metastasis potential

1990 • 164 citations

Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1.

1992 • 155 citations

A Murine Renal Cell Carcinoma

1973 • 149 citations

Cytokine-induced pseudopodial protrusion is coupled to tumour cell migration

1987 • 147 citations

CYCLOSPORINE STIMULATES EXPRESSION OF TRANSFORMING GROWTH FACTOR-β IN RENAL CELLS POSSIBLE MECHANISM OF CYCLOSPORINES ANTIPROLIFERATIVE EFFECTS

1995 • 131 citations

REGULATION OF NEW DNA SYNTHESIS IN MAMMALIAN CELLS BY CYCLOSPORINE

1994 • 130 citations

Chronic exposure of cultured transformed mouse epidermal cells to transforming growth factor-beta 1 induces an epithelial-mesenchymal transdifferentiation and a spindle tumoral phenotype.

1995 • 105 citations

Effects of Transforming Growth Factor-beta on Human Pulmonary Adenocarcinoma Cell Adhesion, Motility, and Invasion In Vitro

1992 • 73 citations

Homozygous scid/scid;beige/beige mice have low levels of spontaneous or neonatal T cell-induced B cell generation.

1993 • 72 citations

Intrinsic connective tissue abnormalities in the heart muscle of cardiomyopathic Syrian hamsters.

1987 • 32 citations

Cyclosporine stimulates hepatocyte proliferation and accelerates development of hepatocellular carcinomas in rats

1993 • 31 citations

Quantitative Study of Liver Metastases From Colon Cancer in Rats After Treatment With Cyclosporine A<xref ref-type="fn" rid="FN1">2</xref>

1986 • 28 citations

Effects of Cyclosporin A on Progressive and Regressive Tumors Induced by Two Cancer Lines Derived from a Single Colon Carcinoma Chemically Induced in the Rat

1989 • 27 citations

Cyclosporin A enhances locoregional metastasis of the CC531 rat colon tumour

1997 • 27 citations

Coupling of cytoskeleton functions for fibroblast locomotion.

1985 • 19 citations

Immunostimulatory Therapy With Anti-CD3 Monoclonal Antibodies and Recombinant Interleukin-2: Heightened In Vivo Expression of mRNA Encoding Cytotoxic Attack Molecules and Immunoregulatory Cytokines and Regression of Murine Renal Cell Carcinoma

1997 • 7 citations

Deleted Work

1955 • 0 citations