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β-adrenergic antagonists attenuate withdrawal anxiety in cocaine-and morphine-dependent rats

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Methylenedioxymethamphetamine (MDMA, ‘Ecstasy’): a stressor on the immune system

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Diurnal Activity and Pulsatility of the Hypothalamus-Pituitary-Adrenal System in Male Depressed Patients and Healthy Controls

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Effects of repeated psychostimulant administration on the prodynorphin system activity and kappa opioid receptor density in the rat brain

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Dopamine D2L receptor knockout mice display deficits in positive and negative reinforcing properties of morphine and in avoidance learning

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Anterior pituitary, adrenal, and gonadal hormones during cocaine withdrawal

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Effects of Withdrawal from an Escalating Dose Schedule of d-Amphetamine on Sexual Behavior in the Male Rat

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Chronic Fluoxetine Treatment Partly Attenuates the Long-Term Anxiety and Depressive Symptoms Induced by MDMA (‘Ecstasy’) in Rats

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The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal

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Animal models of craving for ethanol

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Phosphatidylinositol 3-Kinase, Protein Kinase C, and MEK1/2 Kinase Regulation of Dopamine Transporters (DAT) Require N-terminal DAT Phosphoacceptor Sites

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Overview of antidepressants currently used to treat anxiety disorders.

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Depression and Stimulant Dependence

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Bromocriptine reverses the elevation in intracranial self-stimulation thresholds observed in a rat model of cocaine withdrawal.

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Withdrawal from IV cocaine "binges" in rats: ultrasonic distress calls and startle

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Role of Adenosine A2 Receptors in Brain Stimulation Reward under Baseline Conditions and during Cocaine Withdrawal in Rats

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Cocaine-induced reduction of brain neuropeptide Y synthesis dependent on medial prefrontal cortex.

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Problems with currently available antidepressants.

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Amphetamine derivatives induce locomotor hyperactivity by acting as indirect serotonin agonists

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Bromocriptine‐Desipramine Protocol in Treatment of Cocaine Addiction

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Chronic mild stress has no effect on responding by rats for sucrose under a progressive ratio schedule

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Hyperprolactinemia, distress, and hostility

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A Comparison of Self-Reported Symptoms and DSM-III-R Criteria for Cocaine Withdrawal

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Extracellular serotonin is decreased in the nucleus accumbens during withdrawal from cocaine self-administration

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Regional Differences in the Effects of Amphetamine Withdrawal on Dopamine Dynamics in the Striatum Analysis of Circadian Patterns Using Automated On-Line Microdialysis

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The topographical features of EEGs in patients with affective disorders

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Withdrawal from Chronic Phencyclidine Treatment Induces Long-Lasting Depression in Brain Reward Function

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Awakening properties of modafinil without paradoxical sleep rebound: comparative study with amphetamine in the rat

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CRF and urocortin decreased brain stimulation reward in the rat: reversal by a CRF receptor antagonist

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Changes in serotonin and norepinephrine uptake sites after chronic cocaine: pre- vs. post-withdrawal effects

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Paradoxical effects of chronic corticosterone on forced swim behaviours in aged male and female rats

2001 • 68 citations

Cocaine withdrawal produces behavioral disruptions in rats

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Bromocriptine Therapy in Cocaine Withdrawal

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Polygraphic sleep measures differentiate alcoholics and stimulant abusers during short-term abstinence

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Withdrawal from morphine or amphetamine: different effects on dopamine in the ventral-medial striatum studied with microdialysis

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Bromocriptine and amantadine in cocaine detoxification

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Persistent reduction of immediate early gene mRNA in rat forebrain following single or multiple doses of cocaine

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Subjective Experience and Dopamine D₂ Receptor Occupancy in Patients Treated with Antipsychotics: Clinical Implications

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Repeated Administration of Amphetamine or Cocaine Does Not Alter AMPA Receptor Subunit Expression in the Rat Midbrain,

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The effects of lisuride on mood and sleep during acute withdrawal in stimulant abusers: A preliminary report

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Elevated hypothalamic/midbrain serotonin (monoamine) transporter availability in depressive drug-naive children and adolescents

2000 • 62 citations

Typology of common psychiatric syndromes

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Expression of dopamine transporter and vesicular monoamine transporter 2 mRNAs in rat midbrain after repeated amphetamine administration

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Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment

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Strategies for studying the neurochemical substrates of drug reinforcement in rodents

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Nicotine-induced decreases in VTA electrical self-stimulation thresholds: blockade by haloperidol and mecamylamine but not scopolamine or ondansetron

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A comparison of the effects of clonidine and CNQX infusion into the locus coeruleus and the amygdala on naloxone-precipitated opiate withdrawal in the rat

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Dopamine Partial Agonist Reverses Amphetamine Withdrawal in Rats

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Serotonin, Carbohydrates, and Atypical Depression

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Regulation of NMDA Receptor Subunits and Nitric Oxide Synthase Expression During Cocaine Withdrawal

2000 • 59 citations

Double-blind comparison of amantadine and bromocriptine for ambulatory withdrawal from cocaine dependence

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Exposure to Repeated, Intermittent d-amphetamine Induces Sensitization of HPA Axis to a Subsequent Stressor

2002 • 58 citations

Anxiogenic properties of cocaine withdrawal

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Brain transcription factor gene expression, neurotransmitter levels, and novelty response behaviors: Alterations during rat amphetamine withdrawal and following chronic injection stress

1995 • 58 citations

Increased CRH mRNA levels in the rat amygdala during short-term withdrawal from chronic ‘binge’ cocaine

2003 • 57 citations

High levels of estradiol impair spatial performance in the Morris water maze and increase ‘depressive-like’ behaviors in the female meadow vole

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Venlafaxine Treatment of Cocaine Abusers with Depressive Disorders

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Clozapine and Haloperidol Reinstate Latent Inhibition Following its Disruption during Amphetamine Withdrawal

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Carbohydrate Craving

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Abnormalities of presynaptic protein CDCrel‐1 in striatum of rats reared in social isolation: relevance to neural connectivity in schizophrenia

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Effects of cocaine on conflict behavior in the rat

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Disruption of Th1/Th2 cytokine balance by cocaine is mediated by corticosterone

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Neuroendocrine-Related Effects of Long-Term, ‘Binge’ Cocaine Administration: Diminished Individual Differences in Stress-Induced Corticosterone Response

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Extinction Training Regulates Tyrosine Hydroxylase during Withdrawal from Cocaine Self-Administration

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Neurochemical correlates of relapse to d-amphetamine self-administration by rats induced by stimulation of the ventral subiculum

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Increased successive negative contrast in rats withdrawn from an escalating-dose schedule of d-amphetamine

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Dextroamphetamine as a treatment for depression and low energy in AIDS patients: A pilot study

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Alterations in hypothalamic–pituitary–adrenal axis activity and in levels of proopiomelanocortin and corticotropin-releasing hormone-receptor 1 mRNAs in the pituitary and hypothalamus of the rat during chronic ‘binge’ cocaine and withdrawal

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AMPHETAMINE WITHDRAWAL: DEPRESSION AND M.H.P.G. EXCRETION

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Effects of abused drugs on thresholds and breaking points of intracranial self-stimulation in rats

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Neuroadaptive Changes in NMDAR1 Gene Expression after Extinction of Cocaine Self‐Administration

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Pindolol binding to 5-HT 1A receptors in the human brain confirmed with positron emission tomography

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Treatment of Heroin (Diamorphine) Addiction

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Assessment of tyrosine hydroxylase immunoreactive innervation in five subregions of the nucleus accumbens shell in rats treated with repeated cocaine

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Latent inhibition, but not prepulse inhibition, is reduced during withdrawal from an escalating dosage schedule of amphetamine.

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Decreased Striatal Dopamine D₁Receptor- Stimulated Adenylyl Cyclase Activity in Human Methamphetamine Users

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Cocaine differentially regulates activator protein-1 mRNA levels and DNA-binding complexes in the rat striatum and cerebellum.

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Cocaine and the AP‐1 Transcription Factor Complex

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Evidence for alterations in presynaptic serotonergic function during withdrawal from chronic cocaine in rats

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Impaired DRL 30 performance during amphetamine withdrawal

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Latent inhibition, but not prepulse inhibition, is reduced during withdrawal from an escalating dosage schedule of amphetamine.

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The influence of stress on psychopharmacological responses to nicotine

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Bromocriptine in depression

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Reaction time during cocaine versus alcohol withdrawal: Longitudinal measures of visual and auditory suppression

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Lack of persistent changes in the dopaminergic system of rats withdrawn from methamphetamine self-administration

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Simultaneous analyses of the neurochemical and behavioral effects of the norepinephrine reuptake inhibitor reboxetine in a rat model of antidepressant action

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Phenomenology and treatment of agitation.

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Effects of withdrawal from chronic amphetamine intoxication on exploratory and stereotyped behaviors in the rat

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Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests

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Chronic corticosterone enhances the rewarding effect of hypothalamic self-stimulation in rats

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The elevation of plasma β-endorphin levels in major depression

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Lisuride Reduces Psychomotor Retardation during Withdrawal from Chronic Intravenous Amphetamine Self-Administration in Rats

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Neurophysiological signs of cocaine dependence: Increased electroencephalogram beta during withdrawal

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Dopamine transporters are dephosphorylated in striatal homogenates and in vitro by protein phosphatase 1

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Pergolide mesylate treatment of cocaine withdrawal.

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Dopaminergic sensitivity and cocaine abuse: Response to apomorphine

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Opposite effects of stress on dopamine release in the limbic system of drug-naive and chronically amphetamine-treated rats

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Reduction of zif268 messenger RNA expression during prolonged withdrawal following “binge” cocaine self-administration in rats

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Repeated cocaine administration differentially affects NMDA receptor subunit (NR1, NR2A‐C) mRNAs in rat brain

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The acquisition, retention and reversal of spatial learning in the morris water maze task following withdrawal from an escalating dosage schedule of amphetamine in wistar rats

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Endocrine, immune, and neurochemical changes in rats during withdrawal from chronic amphetamine intoxication.

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Pharmacology of amineptine, an antidepressant agent acting on the dopaminergic system

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Methylenedioxymethamphetamine Suppresses Production of the Proinflammatory Cytokine Tumor Necrosis Factor-α Independent of a β-Adrenoceptor-Mediated Increase in Interleukin-10

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The serotonin/noradrenaline-link in brain

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Animal models in cognitive behavioural pharmacology: an overview

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Double-Blind Comparison of Bromocriptine and Placebo in Cocaine Withdrawal

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Clozapine treatment attenuated somatic and affective signs of nicotine and amphetamine withdrawal in subsets of rats exhibiting hyposensitivity to the initial effects of clozapine

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Evidence for alterations in α2-adrenergic receptor sensitivity in rats exposed to repeated cocaine administration

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The influence of prolonged amphetamine treatment and amphetamine withdrawal on brain biogenic amine content and behaviour in the rat

1971 • 34 citations

Adaptive changes in the proenkephalin and D2 dopamine receptor mRNA expression after chronic cocaine in the nucleus accumbens and striatum of the rat

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Amphetamine Withdrawal: II. A Placebo-Controlled, Randomised, Double-Blind Study of Amineptine Treatment

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Desipramine Facilitation of Cocaine Abstinence in an Adolescent

1992 • 33 citations

Effects of cocaine administration on receptor binding and subunits mRNA of GABAA-benzodiazepine receptor complexes

2000 • 32 citations

The consequences of different "lapses" on relapse to heroin seeking in rats.

2002 • 32 citations

Stress-Induced Suppression of the Immune System after Withdrawal from Chronic Cocaine

2003 • 32 citations

Noradrenaline and 5-hydroxytryptamine metabolism in six areas of rat brain during post-amphethamine depression

1974 • 31 citations

Cocaine treatment- and withdrawal-induced alterations in the expression and serine phosphorylation of the NR1 NMDA receptor subunit

2002 • 31 citations

Impact of nicotine withdrawal on novelty reward and related behaviors.

2003 • 31 citations

Behavioral depression during cocaine withdrawal is associated with decreased spontaneous activity of ventral tegmental area dopamine neurons.

2003 • 31 citations

Lasting effects of repeated cocaine administration on acoustic and fear-potentiated startle in rats

1999 • 30 citations

Behavioural consequences of cocaine withdrawal in rats

1994 • 29 citations

The up-regulation of the striatal dopamine transporter?s activity by cAMP is PKA-, CaMK II- and phosphatase-dependent

2004 • 29 citations

Interactions of amineptine with the neuronal dopamine uptake system: Neurochemicalin vitro andin vivo studies

1987 • 29 citations

Measurement of reinforcement in depression: A pilot study

1985 • 29 citations

Cocaine Treatment Causes Early and Long-Lasting Changes in Muscarinic and Dopaminergic Receptors

2004 • 28 citations

Effects of chronic mild stress on motivation for sucrose: mixed messages

1997 • 28 citations

Chronic cocaine treatment induces dysregulation in the circadian pattern of rats’ feeding behavior

2000 • 27 citations

Amphetamine withdrawal modulates FosB expression in mesolimbic dopaminergic target nuclei: effects of different schedules of administration

2003 • 27 citations

Dopaminergic regulation of cholecystokinin mRNA content in rat striatum

1992 • 27 citations

Long‐term changes in connexin32 gap junction protein and mRNA expression following cocaine self‐administration in rats

1999 • 27 citations

The consequences of different "lapses" on relapse to heroin seeking in rats.

2002 • 26 citations

The combination of phentermine and fenfluramine reduced cocaine withdrawal symptoms in an open trial

2000 • 26 citations

Chronic cocaine exposure potentiates prolactin and head shake responses to 5-HT2 receptor stimulation in rats

1996 • 26 citations

Immune cell activity during the initial stages of withdrawal from chronic exposure to cocaine or morphine

2003 • 26 citations

Effect of chronic amphetamine administration on the behaviour of rats in the open field apparatus: reversal of post-withdrawal depression by two antidepressants

1978 • 25 citations

Increases in the Density of Parvalbumin-immunoreactive Neurons in Anterior Cingulate Cortex of Amphetamine-withdrawn Rats: Evidence for Corticotropin-releasing Factor in Sustained Elevation

2004 • 25 citations

Long-term influence of d-amphetamine on mesolimbic brain-stimulation reward: Comparison to chronic haloperidol and naloxone effects

1992 • 25 citations

Tolerance to the anhedonic effects of lipopolysaccharide is associated with changes in syntaxin immunoreactivity in the nucleus accumbens

2003 • 24 citations

Effects of 8-OH-DPAT and WAY-100635 on performance on a time-constrained progressive-ratio schedule

2003 • 24 citations

Dopaminergic gene expression during amphetamine withdrawal

1993 • 24 citations

Repeated electroconvulsive shock attenuates the depressive-like effects of d-amphetamine withdrawal on brain reward function in rats

2001 • 24 citations

Amphetamine administration does not alter protein levels of the GLT-1 and EAAC1 glutamate transporter subtypes in rat midbrain, nucleus accumbens, striatum, or prefrontal cortex

2001 • 23 citations

The effects of cocaine on dietary self-selection in female rats

1993 • 23 citations

Time-dependent alterations in corticotropin-releasing factor-like immunoreactivity in different brain regions after acute cocaine administration to rats

1997 • 23 citations

Effects of ritanserin and chlordiazepoxide on sleep-wakefulness alterations in rats following chronic cocaine treatment

1992 • 22 citations

Behavioral assessment of high-dose amphetamine withdrawal: Importance of training and testing conditions

1994 • 22 citations

Altered sensitivity of dopamine autoreceptors in rat accumbens 1 and 7 days after intermittent or continuous cocaine withdrawal

2000 • 21 citations

1990-1991 Survey of Pharmacotherapies Used in the Treatment of Cocaine Abuse

1993 • 21 citations

Cocaine-seeking behavior after extended cocaine-free periods in rats: role of conditioned stimuli

2002 • 21 citations

Involvement of Acetylcholine in the Nucleus Accumbens in Cocaine Reinforcement

1999 • 21 citations

The progressive changes of neuronal activities of the nigral dopaminergic neurons upon withdrawal from continuous infusion of cocaine

1992 • 21 citations

Contrasting effects of repeated treatment vs. withdrawal of methamphetamine on tyrosine hydroxylase messenger RNA levels in the ventral tegmental area and substantia nigra zona compacta of the rat brain

1996 • 20 citations

Physiological and Subjective Effects of Acute Cocaine Withdrawal (Crash) in Rats

1997 • 20 citations

Diminished reaction to a novel stimulus during amphetamine withdrawal in rats

1976 • 20 citations

Desipramine in the treatment of hypersomnolence following abrupt cessation of cocaine use

1983 • 20 citations

Effects of chronic cocaine exposure on corticotropin-releasing hormone binding protein in the central nucleus of the amygdala and bed nucleus of the stria terminalis

2004 • 20 citations

Time-dependent changes in the sensitivity of dopamine neurons to low doses of apomorphine following amphetamine infusion

1989 • 19 citations

Medial prefrontal cortical injections of c-fos antisense oligonucleotides transiently lower c-Fos protein and mimic amphetamine withdrawal behaviours

1997 • 19 citations

Lack of altered startle responding in rats following termination of self-administered or noncontingently infused cocaine

1994 • 19 citations

Characterizing withdrawal in rats following repeated drug administration using an amphetamine-vehicle-haloperidol drug discrimination

1999 • 18 citations

A Placebo-Controlled Trial of L-DOPA/Carbidopa in Early Cocaine Abstinence

1993 • 18 citations

Bromocriptine for Cocaine Dependence

1997 • 18 citations

Treatment of affective illness in the elderly with drugs and electroconvulsive therapy.

1989 • 16 citations

Changes in brain γ-aminobutyric acid concentrations following acute and chronic amphetamine administration and during post amphetamine depression

1978 • 16 citations

Prepulse inhibition of the acoustic startle response in cocaine-withdrawn rats

2001 • 16 citations

Short-Term Cocaine Treatment Causes Neuroadaptive Changes in Gα_q and Gα₁₁ Proteins in Rats Undergoing Withdrawal

2004 • 16 citations

Increased sensitivity to the locomotor depressant effect of a dopamine receptor antagonist during cocaine withdrawal in the rat

1999 • 15 citations

Therapeutic Effect of Lisuride Maleate on Post-stroke Depression.

1994 • 15 citations

Ritanserin overcomes exploratory inhibition induced by cocaine withdrawal

1992 • 15 citations

Changes in behavioral sensitivity to SKF-38393 and quinpirole following withdrawal from continuous cocaine administration in rats

1996 • 14 citations

The effect of repeated administration of methamphetamine on dopamine uptake sites in rat striatum

1994 • 14 citations

Inhibition of dopamine efflux in the rat nucleus accumbens during abstinence after free access to d-amphetamine

2002 • 14 citations

Phenomenology and neurobiology of cocaine withdrawal: Are they related?

1995 • 14 citations

Cocaine regulates TRH-related peptides in rat brain

2002 • 14 citations

Alterations of calmodulin and its mRNA in rat brain after acute and chronic administration of methamphetamine

1997 • 14 citations

Different Effects of Phenelzine Treatment on EEG Topography in Waking and Sleep in Depressed Patients

2002 • 13 citations

Amineptine in the treatment of amphetamine withdrawal: a placebo-controlled, randomised, double-blind study.

1997 • 13 citations

Models of antidepressant action.

1999 • 13 citations

Different times of withdrawal from cocaine administration cause changes in muscarinic and dopaminergic receptors in rat premotor cortex

2001 • 12 citations

Withdrawal from continuous cocaine administration: time dependent changes in accumbens 5-HT 3 receptor function and behavioral tolerance

1999 • 12 citations

A Rodent Model of Cocaine Abstinence Syndrome

2000 • 11 citations

Prolonged deficits in presynaptic serotonin function following withdrawal from chronic cocaine exposure as revealed by 5-HTP-induced head-twitch response in mice

1997 • 11 citations

Cocaine‐induced Changes in Extracellular Levels of Striatal Dopamine Measured Concurrently by Microdialysis with HPLC‐EC and Chronoamperometry

1992 • 10 citations

Effects of amisulpride on consummatory negative contrast

2002 • 10 citations

Time course of the effect of amphetamine on eating is biphasic.

1989 • 10 citations

Time course of the effect of amphetamine on eating is biphasic.

1989 • 9 citations

Proceedings: Methylamphetamine withdrawal as a model for the depressive state: antagonism of post-amphetamine depression by imipramine.

1975 • 9 citations

Effects in animal models of depression of lisuride alone and upon co-administration with antidepressants.

1989 • 8 citations

Post-amphetamine depression of self-stimulation behavior in rats: Prophylactic effects of lithium

1981 • 8 citations

Depressive stupor following amphetamine withdrawal.

1993 • 7 citations

Gluconeogenic Activity in Response to Chronic Administration of Amphetamine Sulphate and Drug Withdrawal

1997 • 7 citations

A Historically Controlled Trial of Tyrosine for Cocaine Dependence

1996 • 5 citations

Apomorphine-induced Acute Withdrawal in Rats.

2018 • 2 citations

Animal model of depression: imipramine, bromocriptine and lisuride alleviate motor depression.

1986 • 1 citations

Deleted Work

1955 • 0 citations