Acquisition, maintenance and reinstatement of intravenous cocaine self-administration under a second-order schedule of reinforcement in rats: effects of conditioned cues and continuous access to cocaine

Statistical principles in experimental design.

1962 • 27,228 citations

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Abstinence Symptomatology and Psychiatric Diagnosis in Cocaine Abusers

1986 • 1,134 citations

Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants.

1984 • 1,060 citations

Cocaine Addiction: Psychology and Neurophysiology

1991 • 753 citations

The pharmacology of cocaine related to its abuse.

1989 • 685 citations

Dynamics of Drug Dependence

1973 • 608 citations

Animal models of drug craving

1993 • 560 citations

Postcocaine anhedonia. An animal model of cocaine withdrawal.

1991 • 505 citations

Classical Conditioning in Drug‐Dependent Humansa

1992 • 473 citations

Enhanced behavioural control by conditioned reinforcers following microinjections of d-amphetamine into the nucleus accumbens

1984 • 440 citations

Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys.

1989 • 389 citations

Attenuation of intravenous amphetamine reinforcement by central dopamine blockade in rats

1976 • 371 citations

Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement.

1996 • 301 citations

The biological, social and clinical bases of drug addiction: commentary and debate

1996 • 277 citations

Drug reinstatement of heroin-reinforced responding in the rat

1983 • 266 citations

Construct validity of a self-stimulation threshold paradigm: Effects of reward and performance manipulations

1992 • 254 citations

Classically Conditioned Responses in Opioid and Cocaine Dependence: A Role in Relapse?

1988 • 249 citations

A MATHEMATICAL INDEX OF PERFORMANCE ON FIXED‐INTERVAL SCHEDULES OF REINFORCEMENT

1960 • 247 citations

Conditioned cued recovery of responding following prolonged withdrawal from self-administered cocaine in rats: an animal model of relapse.

1996 • 223 citations

Comparable behavior maintained under fixed-ratio and second-order schedules of food presentation, cocaine injection or d-amphetamine injection in the squirrel monkey.

1973 • 213 citations

The acquisition of responding with conditioned reinforcement: Effects of pipradrol, methylphenidate, d-amphetamine, and nomifensine

1978 • 192 citations

Opponent Process Model and Psychostimulant Addiction

1997 • 191 citations

Effects of medial prefrontal or anterior cingulate cortex lesions on responding for cocaine under fixed-ratio and second-order schedules of reinforcement in rats

1997 • 188 citations

Dopamine, addiction and reward

1992 • 179 citations

Relative roles of ventral striatal D1 and D2 dopamine receptors in responding with conditioned reinforcement

1993 • 161 citations

Serotonergic modulation of the behavioral effects of cocaine in the squirrel monkey.

1995 • 135 citations

Studies of instrumental behavior with sexual reinforcement in male rats (Rattus norvegicus): I. Control by brief visual stimuli paired with a receptive female.

1987 • 116 citations

Self-administration of D1 receptor agonists by squirrel monkeys

1996 • 93 citations

Interaction of expectancy and the pharmacological effects ofd-amphetamine: subjective effects and self-administration

1996 • 86 citations

Behavior maintained under a second-order schedule by intramuscular injection of morphine or cocaine in rhesus monkeys.

1976 • 84 citations

Enhancement of drug-seeking behavior by environmental stimuli associated with cocaine or morphine injections

1979 • 76 citations

FIXED‐INTERVAL RESPONDING UNDER SECOND‐ORDER SCHEDULES OF FOOD PRESENTATION OR COCAINE INJECTION¹

1977 • 65 citations

Chlorpromazine effects on cocaine-reinforced responding in rhesus monkeys: reciprocal modification of rate-altering effects of the drugs.

1980 • 65 citations

Fixed-ratio responding under second-order schedules of food presentation or cocaine injection.

1981 • 64 citations

A COMPARISON OF RESPONDING MAINTAINED UNDER SECOND‐ORDER SCHEDULES OF INTRAMUSCULAR COCAINE INJECTION OR FOOD PRESENTATION IN SQUIRREL MONKEYS

1979 • 58 citations

Initiation, maintenance and extinction of cocaine self-administration with and without conditioned reward

1996 • 52 citations

Developing Treatments That Address Classical Conditioning

1993 • 49 citations

COCAINE AND FOOD AS REINFORCERS: EFFECTS OF REINFORCER MAGNITUDE AND RESPONSE REQUIREMENT UNDER SECOND‐ORDER FIXED‐RATIO AND PROGRESSIVE‐RATIO SCHEDULES

1991 • 47 citations

FIXED‐INTERVAL SCHEDULES OF INTRAVENOUS COCAINE PRESENTATION IN RATS¹

1973 • 46 citations

Second-order schedules: extended sequences of behavior controlled by brief environmental stimuli associated with drug self-administration.

1981 • 44 citations

ONLIBASIC, a System for Experimental Control

1980 • 29 citations

Behavior maintained under fixed-interval and second-order schedules of cocaine or pentobarbital in rhesus monkeys.

1982 • 27 citations

Fixed-interval schedules for drug self-administration in the rat

1989 • 27 citations

XXI. Interaction of physical dependence and classical and operant conditioning in the genesis of relapse.

1968 • 27 citations

Comparison of behavior maintained by intravenous cocaine and d-amphetamine in dogs.

1984 • 11 citations