Role for M₅ muscarinic acetylcholine receptors in cocaine addiction

Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues

1998 • 1,247 citations

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

1988 • 792 citations

Cocaine Addiction: Psychology and Neurophysiology

1991 • 753 citations

The neurobiology of drug addiction

1997 • 564 citations

Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats

1989 • 562 citations

Exploration of mice in a black and white test box: Validation as a model of anxiety

1989 • 535 citations

Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia.

1990 • 473 citations

Synapse formation between central neurons requires postsynaptic expression of the MEN1 tumor suppressor gene.

2001 • 469 citations

Differences in anxiety-related behaviours and in sensitivity to diazepam in inbred and outbred strains of mice

2000 • 407 citations

Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area

1995 • 371 citations

Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M ₄ muscarinic acetylcholine receptor knockout mice

1999 • 307 citations

Laterodorsal tegmental stimulation elicits dopamine efflux in the rat nucleus accumbens by activation of acetylcholine and glutamate receptors in the ventral tegmental area

2000 • 268 citations

Localization of m5 muscarinic receptor mRNA in rat brain examined by in situ hybridization histochemistry

1990 • 268 citations

Cholinergic dilation of cerebral blood vessels is abolished in M ₅ muscarinic acetylcholine receptor knockout mice

2001 • 264 citations

Brain corticotropin-releasing factor mediates ‘anxiety-like’ behavior induced by cocaine withdrawal in rats

1995 • 256 citations

Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and laterodorsal tegmental nucleus-lesioned rats

1996 • 211 citations

Cholinergic input to dopaminergic neurons in the substantia nigra: A double immunocytochemical study

1991 • 210 citations

Development of antisera selective for m4 and m5 muscarinic cholinergic receptors: distribution of m4 and m5 receptors in rat brain.

1993 • 208 citations

The tegmental pedunculopontine nucleus: a brain-stem output of the limbic system critical for the conditioned place preferences produced by morphine and amphetamine

1989 • 206 citations

Cocaine reinforcement and extracellular dopamine overflow in rat nucleus accumbens: an in vivo microdialysis study

1989 • 204 citations

Deletion of the M ₅ muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia

2002 • 190 citations

The actions of nicotine and cocaine in a mouse model of anxiety

1989 • 188 citations

Muscarine depolarizes rat substantia nigra zona compacta and ventral tegmental neurons in vitro through M1-like receptors.

1990 • 156 citations

M5 Muscarinic Receptors Are Required for Prolonged Accumbal Dopamine Release after Electrical Stimulation of the Pons in Mice

2002 • 148 citations

Reinforcing Effects of Nicotinic Compounds Intravenous Self-administration in Drug-Naive Mice

1998 • 73 citations

Brain-Stimulation Reward Thresholds Raised by an Antisense Oligonucleotide for the M5 Muscarinic Receptor Infused near Dopamine Cells

2000 • 73 citations

Effects of pedunculopontine tegmental nucleus lesions on morphine-induced conditioned place preference and analgesia in the formalin test

1993 • 69 citations

Potentiation of central reward by localised perfusion of acetylcholine and 5-hydroxytryptamine

1976 • 59 citations