Dopamine D2L receptor knockout mice display deficits in positive and negative reinforcing properties of morphine and in avoidance learning

A Neural Substrate of Prediction and Reward

1997 • 8,991 citations

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene

1996 • 1,652 citations

Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues

1998 • 1,247 citations

The Structure and Organization of Memory

1993 • 1,092 citations

Neurobiology of addiction

1996 • 1,082 citations

Neuroscience of Addiction

1998 • 1,030 citations

Alternative splicing directs the expression of two D2 dopamine receptor isoforms

1989 • 692 citations

Multiple D2 dopamine receptors produced by alternative RNA splicing

1989 • 642 citations

The dopamine D2 receptor: two molecular forms generated by alternative splicing.

1989 • 596 citations

The involvement of nucleus accumbens dopamine in appetitive and aversive motivation

1994 • 580 citations

PROCEDURAL LEARNING AND NEOSTYRIAL DYSFUNCTION IN MAN

1988 • 534 citations

Cocaine reward models: Conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice

1998 • 502 citations

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

1997 • 481 citations

Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

1997 • 435 citations

Dissociation of Pavlovian and instrumental incentive learning under dopamine antagonists.

2000 • 290 citations

Sensitization to the conditioned rewarding effects of cocaine: pharmacological and temporal characteristics.

1995 • 263 citations

Dissociation of Pavlovian and instrumental incentive learning under dopamine antagonists.

2000 • 244 citations

Effects of dopaminergic and glutamatergic receptor antagonists on the acquisition and expression of cocaine conditioning place preference

1995 • 239 citations

Addiction to Cocaine and Amphetamine

1996 • 234 citations

Dopamine D2 Long Receptor-Deficient Mice Display Alterations in Striatum-Dependent Functions

2000 • 192 citations

The D2 dopamine receptor isoforms signal through distinct Gi alpha proteins to inhibit adenylyl cyclase. A study with site-directed mutant Gi alpha proteins.

1994 • 191 citations

Effects of dopamine D(1-like) and D(2-like) agonists in rats that self-administer cocaine.

1999 • 147 citations

Substance abuse vulnerability and D2 receptor genes

1993 • 141 citations

Electrical stimulation of reward sites in the ventral tegmental area increases dopamine transmission in the nucleus accumbens of the rat

1993 • 130 citations

Dopaminergic substrates of cocaine-induced place conditioning

1986 • 116 citations

A Selective AMPA Antagonist, LY293558, Suppresses Morphine Withdrawal-Induced Activation of Locus Coeruleus Neurons and Behavioral Signs of Morphine Withdrawal

1996 • 115 citations

Neuroleptic-like distruption of the conditioned avoidance response requires destruction of both the mesolimbic and nigrostriatal dopamine systems

1984 • 110 citations

Involvement of the σ1 receptor in the cocaine-induced conditioned place preference

2000 • 106 citations

Reward and reinforcement produced by drinking sucrose: Two processes that may depend on different neurotransmitters

1995 • 102 citations

The NMDA antagonist dizocilpine (MK801) attenuates motivational as well as somatic aspects of naloxone precipitated opioid withdrawal

1992 • 87 citations

Post-training dopamine receptor agonists and antagonists affect memory storage in mice irrespective of their selectivity for D1 or D2 receptors

1991 • 82 citations

Continued Trends in the Conditioned Place Preference Literature from 1992 to 1996, Inclusive, with a Cross-Indexed Bibliography

1998 • 74 citations

Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats.

1999 • 73 citations

Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice

2002 • 71 citations

Naloxone-Precipitated Morphine Withdrawal Induced Place Aversions Effect of Naloxone at 24 Hours Postmorphine

1998 • 59 citations

Effects of dopamine D1 and D2 receptor antagonists on cocaine-induced place preference conditioning in preweanling rats

1995 • 55 citations

Differential expression of dopaminergic D2 receptor messenger RNAs during development

1991 • 46 citations

The Mouse Dopamine D2_A Receptor Gene: Sequence Homology with the Rat and Human Genes and Expression of Alternative Transcripts

1991 • 41 citations

Dopamine D2L receptor- and age-related reduction in offensive aggression

2001 • 40 citations

Role of Gustatory and Postingestive Actions of Sweeteners in the Generation of Positive Affect as Evaluated by Place Preference Conditioning

1997 • 39 citations

Long-term haloperidol administration enhances and short-term administration attenuates the behavioral effects of cocaine in a place conditioning procedure

1996 • 35 citations

The effects of dopamine and D2 receptor antagonists on pituitary hormone secretion are intact in mice lacking dopamine D2L receptor

2002 • 14 citations

Dopamine D2L Receptor Knockout Mouse Provides a Unique Model System for Studying the Functions of D2L and D2S

2002 • 4 citations

Regional brain patterns of dopamine, metabolites and D2 receptors in memory

1996 • 2 citations