Impact of nicotine withdrawal on novelty reward and related behaviors.

Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues

1998 • 1,247 citations

Conditioned place preference: what does it add to our preclinical understanding of drug reward?

2000 • 1,210 citations

Dramatic decreases in brain reward function during nicotine withdrawal

1998 • 676 citations

NOVELTY AND CURIOSITY AS DETERMINANTS OF EXPLORATORY BEHAVIOUR¹

1950 • 500 citations

The neuropharmacological basis of reward

1991 • 457 citations

The effects of nicotine on locomotor activity in non‐tolerant and tolerant rats

1983 • 457 citations

Conditioned place preference as a measure of drug reward.

1989 • 456 citations

Symptoms of Tobacco Withdrawal

1991 • 449 citations

Rodent model of nicotine abstinence syndrome

1992 • 326 citations

Nucleus accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal

1990 • 317 citations

Effect of nicotine on the tobacco withdrawal syndrome

1984 • 293 citations

The effect of bupropion on nicotine craving and withdrawal

2000 • 264 citations

Effects of dopaminergic and glutamatergic receptor antagonists on the acquisition and expression of cocaine conditioning place preference

1995 • 239 citations

Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects.

2000 • 213 citations

Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome

1998 • 201 citations

Nicotine enhances sustained attention in the rat under specific task conditions

1998 • 180 citations

The nicotinic antagonist mecamylamine precipitates nicotine abstinence syndrome in the rat

1994 • 168 citations

Fluoxetine Combined with a Serotonin-1A Receptor Antagonist Reversed Reward Deficits Observed during Nicotine and Amphetamine Withdrawal in Rats

2001 • 166 citations

Motivational effects of opioids: influence of D-1 versus D-2 receptor antagonists

1988 • 156 citations

Chronic nicotine and locomotor activity: influences of exposure dose and test dose

1987 • 145 citations

Chronic nicotine and withdrawal effects on radial-arm maze performance in rats

1990 • 133 citations

Effects of nicotine withdrawal on central dopaminergic systems

1996 • 108 citations

The Neuropharmacological Basis of Reward

1991 • 103 citations

Behavioral and Biochemical Manifestations of Mecamylamine-Precipitated Nicotine Withdrawal in the Rat Role of Nicotinic Receptors in the Ventral Tegmental Area

1999 • 102 citations

Conditioned increase in place preference by access to novel objects: antagonism by MK-801

1999 • 98 citations

Psychopharmacology of conditioned reward: evidence for a rewarding signal at D 1 -like dopamine receptors

1999 • 97 citations

Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats

2000 • 94 citations

Mecamylamine-precipitated nicotine-withdrawal aversion in rats

1996 • 92 citations

Novel-object place conditioning: behavioral and dopaminergic processes in expression of novelty reward

2002 • 92 citations

What is the nature of mecamylamine's antagonism of the central effects of nicotine?

1989 • 92 citations

Dopamine antagonism in a novel-object recognition and a novel-object place conditioning preparation with rats

1999 • 88 citations

Time-course of changes in the social interaction test of anxiety following acute and chronic administration of nicotine

1999 • 87 citations

Nicotine withdrawal: a behavioral assessment using schedule controlled responding, locomotor activity, and sensorimotor reactivity

1993 • 82 citations

Prospective study of factors influencing the development of craving associated with smoking cessation

1991 • 81 citations

Nicotine-conditioned locomotor activity in rats: dopaminergic and GABAergic influences on conditioned expression

2001 • 79 citations

Preference for familiar versus novel stimuli as a function of the familiarity of the environment.

1969 • 69 citations

Novelty Seeking and Reward: Implications for the Study of High-Risk Behaviors

2001 • 60 citations

The role of environmental familiarization in novel-object preference

2000 • 56 citations

Selectivec-fos induction and decreased dopamine release in the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome

2000 • 52 citations

Dopaminergic and cholinergic antagonism in a novel-object detection task with rats

2001 • 47 citations

Chronic treatments with cholinoceptor drugs influence spatial learning in rats

1993 • 38 citations

Nitric oxide mediates mecamylamine- and naloxone-precipitated nicotine withdrawal

1998 • 28 citations

Mecamylamine-precipitated nicotine-withdrawal aversion in Lewis and Fischer 344 inbred rat strains

1999 • 28 citations

Randomised controlled trial of ondansetron in smoking cessation

1996 • 24 citations

Effect of chronic nicotine on brain stimulation reward. II. An escalating dose regimen

1998 • 20 citations

Environmental Familiarization in Rats: Differential Effects of Acute and Chronic Nicotine

2001 • 13 citations

Nicotine enhances acquisition of a T-maze visual discrimination: assessment of individual differences

2000 • 7 citations