Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

Matrix Elasticity Directs Stem Cell Lineage Specification

2006 • 12,751 citations

Tensional homeostasis and the malignant phenotype

2005 • 3,655 citations

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

2009 • 3,650 citations

Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion

2005 • 3,543 citations

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

2007 • 3,082 citations

Taking Cell-Matrix Adhesions to the Third Dimension

2001 • 2,940 citations

Genes that mediate breast cancer metastasis to lung

2005 • 2,834 citations

Collective cell migration in morphogenesis, regeneration and cancer

2009 • 2,503 citations

Stromal fibroblasts in cancer initiation and progression

2004 • 2,230 citations

Modeling Tissue Morphogenesis and Cancer in 3D

2007 • 1,672 citations

Collagen reorganization at the tumor-stromal interface facilitates local invasion

2006 • 1,626 citations

Calculation of thermal noise in atomic force microscopy

1995 • 1,526 citations

Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice

2001 • 1,517 citations

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

2007 • 1,446 citations

The multiple faces of caveolae

2007 • 1,395 citations

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

2011 • 1,159 citations

Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities

2001 • 1,144 citations

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells

2001 • 854 citations

Adhesion-Dependent Cell Mechanosensitivity

2003 • 847 citations

Tensile forces govern germ-layer organization in zebrafish

2008 • 766 citations

A detergent-free method for purifying caveolae membrane from tissue culture cells.

1995 • 732 citations

One-dimensional topography underlies three-dimensional fibrillar cell migration

2009 • 701 citations

The myofibroblast: Paradigm for a mechanically active cell

2009 • 617 citations

Rho-mediated Contractility Exposes a Cryptic Site in Fibronectin and Induces Fibronectin Matrix Assembly

1998 • 589 citations

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

2008 • 468 citations

Integrin Dynamics and Matrix Assembly

2000 • 459 citations

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

2002 • 434 citations

Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization

2005 • 414 citations

Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis

2003 • 375 citations

Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases

2007 • 324 citations

Force activates smooth muscle α-actin promoter activity through the Rho signaling pathway

2007 • 313 citations

Caveolin-1 in tumor progression: the good, the bad and the ugly

2008 • 285 citations

An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers

2009 • 279 citations

Preparation of Extracellular Matrices Produced by Cultured and Primary Fibroblasts

2016 • 243 citations

Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice

2003 • 239 citations

Stroma-Derived Three-Dimensional Matrices Are Necessary and Sufficient to Promote Desmoplastic Differentiation of Normal Fibroblasts

2005 • 233 citations

Stromal Cell Expression of Caveolin-1 Predicts Outcome in Breast Cancer

2009 • 186 citations

Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1

2008 • 184 citations

Multiscale Modeling of Form and Function

2009 • 178 citations

Angiopoietin-1 Requires p190 RhoGAP to Protect against Vascular Leakage in Vivo

2007 • 172 citations

Stromagenesis During Tumorigenesis: Characterization of Tumor-associated Fibroblasts and Stroma-derived 3D Matrices

2009 • 111 citations

Breast cancer by proxy: can the microenvironment be both the cause and consequence?

2008 • 104 citations

Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts

2007 • 101 citations

Vascular Permeability and Pathological Angiogenesis in Caveolin-1-Null Mice

2009 • 91 citations

Caveolin-1 Loss of Function Accelerates Glucose Transporter 4 and Insulin Receptor Degradation in 3T3-L1 Adipocytes

2009 • 89 citations

Preparation of Extracellular Matrices Produced by Cultured and Primary Fibroblasts

2006 • 86 citations

Coordination of Rho and Rac GTPase Function via p190B RhoGAP

2008 • 84 citations

Stromal and Epithelial Caveolin-1 Both Confer a Protective Effect Against Mammary Hyperplasia and Tumorigenesis

2006 • 75 citations

The Absence of Caveolin-1 Increases Proliferation and Anchorage- Independent Growth by a Rac-Dependent, Erk-Independent Mechanism

2009 • 73 citations

Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: Implications for tumor progression and clinical outcome

2008 • 71 citations

Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner

2008 • 48 citations

Distance-dependent cellular palmitoylation of de-novo-designed sequences and their translocation to plasma membrane subdomains

2002 • 47 citations

Mice with cav-1 gene disruption have benign stromal lesions and compromised epithelial differentiation

2007 • 29 citations