Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

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Classification and Regression Trees.

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Classification and regression trees

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Tensional homeostasis and the malignant phenotype

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Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion

2005 • 3,543 citations

Tumour-cell invasion and migration: diversity and escape mechanisms

2003 • 3,069 citations

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

2006 • 2,597 citations

Breast Density and Parenchymal Patterns as Markers of Breast Cancer Risk: A Meta-analysis

2006 • 1,991 citations

The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies

2002 • 1,941 citations

Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation

2003 • 1,631 citations

Collagen reorganization at the tumor-stromal interface facilitates local invasion

2006 • 1,626 citations

Compensation mechanism in tumor cell migration

2003 • 1,360 citations

Collagen density promotes mammary tumor initiation and progression

2008 • 1,293 citations

Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms

2003 • 1,243 citations

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

2004 • 1,127 citations

Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

2003 • 1,049 citations

Direct Visualization of Macrophage-Assisted Tumor Cell Intravasation in Mammary Tumors

2007 • 1,011 citations

In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia

2007 • 915 citations

Stromal Effects on Mammary Gland Development and Breast Cancer

2002 • 902 citations

Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation

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Mammographic densities and breast cancer risk.

1998 • 804 citations

Interpreting Second-Harmonic Generation Images of Collagen I Fibrils

2004 • 794 citations

Cancer cells compress intratumour vessels

2004 • 781 citations

Macrophages Promote the Invasion of Breast Carcinoma Cells via a Colony-Stimulating Factor-1/Epidermal Growth Factor Paracrine Loop

2005 • 714 citations

Lumican Regulates Collagen Fibril Assembly: Skin Fragility and Corneal Opacity in the Absence of Lumican

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Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

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Heritability of Mammographic Density, a Risk Factor for Breast Cancer

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ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix

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Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

2008 • 468 citations

Pregnancy-associated breast cancer and metastasis

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Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling.

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Macrophages define the invasive microenvironment in breast cancer

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Polarization-Modulated Second Harmonic Generation in Collagen

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Tumor-associated macrophages in breast cancer.

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Tree-structured survival analysis.

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Alternatively Activated Macrophages and Collagen Remodeling Characterize the Postpartum Involuting Mammary Gland across Species

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Mammographic density is related to stroma and stromal proteoglycan expression

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Alterations of the extracellular matrix in ovarian cancer studied by Second Harmonic Generation imaging microscopy

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Transgenic Polyoma middle-T mice model premalignant mammary disease.

2001 • 250 citations

Remodeling of the Mammary Microenvironment after Lactation Promotes Breast Tumor Cell Metastasis

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Neutrophil gelatinase-associated lipocalin (NGAL) is a predictor of poor prognosis in human primary breast cancer

2007 • 215 citations

Invasion and metastasis

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Human breast carcinoma desmoplasia is PDGF initiated

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Multiphoton Microscopy of Endogenous Fluorescence Differentiates Normal, Precancerous, and Cancerous Squamous Epithelial Tissues

2005 • 207 citations

Multiphoton microscopy and fluorescence lifetime imaging microscopy (FLIM) to monitor metastasis and the tumor microenvironment

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Coordinated Regulation of Pathways for Enhanced Cell Motility and Chemotaxis Is Conserved in Rat and Mouse Mammary Tumors

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The complexities of breast cancer desmoplasia

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Image Correlation Spectroscopy of Multiphoton Images Correlates with Collagen Mechanical Properties

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Quantitative second-harmonic generation microscopy in collagen

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Endogenous Optical Biomarkers of Ovarian Cancer Evaluated with Multiphoton Microscopy

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Simultaneous imaging of GFP, CFP and collagen in tumors in vivousing multiphoton microscopy

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Histologic Grading of Breast Cancer: Linkage of Patient Outcome with Level of Pathologist Agreement

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Syndecan-1 in Breast Cancer Stroma Fibroblasts Regulates Extracellular Matrix Fiber Organization and Carcinoma Cell Motility

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Syndecan-1 expression by stromal fibroblasts promotes breast carcinoma growth in vivo and stimulates tumor angiogenesis

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Fluorescence Lifetime Imaging of Endogenous Fluorophores in Histopathology Sections Reveals Differences Between Normal and Tumor Epithelium in Carcinoma In Situ of the Breast

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Stroma in breast development and disease

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Quantitative Second Harmonic Generation Imaging of the Diseased State Osteogenesis Imperfecta: Experiment and Simulation

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Syndecan-1 and syndecan-4 are overexpressed in an estrogen receptor-negative, highly proliferative breast carcinoma subtype

2006 • 113 citations

Mammographic density, lobular involution, and risk of breast cancer

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Simultaneous two-photon spectral and lifetime fluorescence microscopy

2004 • 102 citations

Second-harmonic generation in collagen as a potential cancer diagnostic parameter

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Quantification of the second-order nonlinear susceptibility of collagen I using a laser scanning microscope

2007 • 86 citations

High Mammographic Breast Density Is Independent Predictor of Local But Not Distant Recurrence After Lumpectomy and Radiotherapy for Invasive Breast Cancer

2008 • 72 citations

Macrophages in Breast Cancer: Do Involution Macrophages Account for the Poor Prognosis of Pregnancy-Associated Breast Cancer?

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Juvenile syndecan-1 null mice are protected from carcinogen-induced tumor development

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Shining new light on 3D cell motility and the metastatic process

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Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix

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Stromal changes in invasive breast carcinoma: An ultrastructural study

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Quantitative analysis of structural disorder in intervertebral disks using second harmonic generation imaging: comparison with morphometric analysis

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Applications of Combined Spectral Lifetime Microscopy for Biology

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Wnt signaling induces differentiation of progenitor cells in organotypic keratinocyte cultures

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Computer-generated nuclear features compared with axillary lymph node status and tumor size as indicators of breast cancer survival

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