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Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

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Smoking a Single Cigarette Rapidly Reduces Combined Concentrations of Nitrate and Nitrite and Concentrations of Antioxidants in Plasma

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Noninvasive measures of oxidative stress status in humans

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Cigarette Smoke Induces an Unfolded Protein Response in the Human Lung

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The renal risks of smoking

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Proposed uniform nomenclature for mammalian ribosomal proteins

1979 • 200 citations

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50-S Ribosomal Proteins. Purification and Partial Characterization of Two Acidic Proteins, A1 and A2, Isolated from 50-S Ribosomes of Escherichia coli

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Metabolism of Polycyclic Aromatic Hydrocarbon Derivatives to Ultimate Carcinogens During Lipid Peroxidation

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Immunological screening method to detect specific translation products.

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Covalent DNA Damage in Tissues of Cigarette Smokers as Determined by 32P-Postlabeling Assay

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Cigarette smoke-induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis

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Inhibition of Carcinogenesis by minor Anutrient Constituents of the Diet

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The Tobacco Epidemic in the United States

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Cigarette smoke irreversibly modifies glutathione in airway epithelial cells

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Systemic effects of COPD

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Tobacco Control in the United States--Recent Progress And Opportunities

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Nicotine and pathological angiogenesis

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Analytical Studies on Tobacco-Specific N-Nitrosamines in Tobacco and Tobacco Smoke

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DNA strand breaks in human leukocytes induced by superoxide anion, hydrogen peroxide and tumor promoters are repaired slowly compared to breaks induced by ionizing radiation

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Simple Microassay of Protein with Membrane Filter

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Hypertension and Smoking Are Associated With Reduced Regional Left Ventricular Function in Asymptomatic Individuals

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4-Hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells

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Animal Models of Cigarette Smoke-Induced COPD*

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A National Institutes of Health Workshop report. Free radicals in promotion--a chemical pathology study section workshop.

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Cigarette smoking, emphysema, and damage to alpha 1-proteinase inhibitor

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The metal-mediated formation of hydroxyl radical by aqueous extracts of cigarette tar

1985 • 108 citations

Human Alveolar Epithelial Cell Injury Induced by Cigarette Smoke

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Impact of chronic cigarette smoking on body composition and fuel metabolism.

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Neutralizing Granulocyte/Macrophage Colony–Stimulating Factor Inhibits Cigarette Smoke–induced Lung Inflammation

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Cigarette smoke and the involvement of free radical reactions in chemical carcinogenesis.

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Cigarette tar causes single-strand breaks in DNA

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Ribosomal proteins. XXV. Immunological studies on Escherichia coli ribosomal proteins

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Streptozotocin-Induced Cytotoxicity, Oxidative Stress and Mitochondrial Dysfunction in Human Hepatoma HepG2 Cells

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Comparative 32P-analysis of cigarette smoke-induced DNA damage in human tissues and mouse skin.

1986 • 85 citations

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Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice

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Genetic Ablation of the Aryl Hydrocarbon Receptor Causes Cigarette Smoke-induced Mitochondrial Dysfunction and Apoptosis

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Prostaglandin synthase-mediated metabolism of carcinogens and a potential role for peroxyl radicals as reactive intermediates.

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Cardiac function in smokers and nonsmokers: The CARDIA study

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Oxidative stress in mouse plasma and lungs induced by cigarette smoke and lipopolysaccharide

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Even moderate cigarette smoking influences the pattern of circulating monocytes and the concentration of sICAM-1

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Does beta-carotene explain why reduced cancer risk is associated with vegetable and fruit intake?

1992 • 78 citations

Pulmonary Lipid Peroxidation in Cigarette Smokers and Lung Cancer Patients

1990 • 77 citations

Active Oxygen Species as Factors in Multistage Carcinogenesis

1991 • 76 citations

Detection of specific hybridoma clones by replica immunoadsorption of their secreted antibodies.

1979 • 75 citations

Prostaglandin H synthase-dependent epoxidation of aflatoxin B₁

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Effect of bitter melon (Momordica Charantia) fruit juice on the hepatic cytochrome P450-dependent monooxygenases and glutathione S-transferases in streptozotocin-induced diabetic rats

1996 • 70 citations

Roles of alcohol and tobacco exposure in the development of hepatocellular carcinoma

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The ESR Properties, DNA Nicking, and DNA Association of Aged Solutions of Catechol Versus Aqueous Extracts of Tar from Cigarette Smoke

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Smoke cardiomyopathy: disturbance of oxidative processes in myocardial mitochondria

1984 • 69 citations

Aqueous extracts of cigarette tar containing the tar free radical cause DNA nicks in mammalian cells.

1994 • 69 citations

Effect of cigarette smoking on nitric oxide, structural, and mechanical properties of mouse arteries

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Oxidation of (+)-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by mouse keratinocytes: evidence for peroxyl radical- and monoxygenase-dependent metabolism

1986 • 67 citations

Are mitochondria a spontaneous and permanent source of reactive oxygen species?

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Electron spin resonance study on the permeability of superoxide radicals in lipid bilayers and biological membranes

1992 • 65 citations

The Levels of Serum Vitamin C, Malonyldialdehyde and Erythrocyte Reduced Glutathione in Chronic Obstructive Pulmonary Disease and in Healthy Smokers

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Expression of SERCA isoform with faster Ca²⁺ transport properties improves postischemic cardiac function and Ca²⁺ handling and decreases myocardial infarction

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Bulky adducts detected by 32P-postlabeling in DNA modified by oxidative damage in vitro. Comparison with rat lung I-compounds

1991 • 62 citations

Systemic inflammation and systemic oxidative stress in patients with acute exacerbations of COPD

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Antibodies reacting with ribosomal ribonucleoprotein in connective tissue diseases

1979 • 57 citations

Evolutionary microdivergence of chick and rat liver ribosomal proteins.

1977 • 57 citations

Model adducts of benzo[a]pyrene and nucleosides formed from its radical cation and diol epoxide

1992 • 57 citations

Systemic Inflammation and Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease: State of the Art and Novel Insights in Regulation of Muscle Plasticity

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Long-term cigarette smoke exposure increases uncoupling protein expression but reduces energy intake

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The inactivation of α-1-proteinase inhibitor by gas-phase cigarette smoke: Protection by antioxidants and reducing species

1986 • 56 citations

Impact of chronic cigarette smoking on body composition and fuel metabolism

1995 • 56 citations

Smoking‐Related Morbidity and Mortality in the Cardiovascular Setting

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Comparison of the vascular effects of adenosine in isolated mouse heart and aorta

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DNA synthesis is blocked by cigarette tar-induced DNA single-strand breaks

1987 • 54 citations

Reaction of hematin with allylic fatty acid hydroperoxides: identification of products and implications for pathways of hydroperoxide-dependent epoxidation of 7,8-dihydroxy-7,8-dihydrobenzol[a]pyrene

1988 • 51 citations

Effects of smoking on systemic and intrarenal hemodynamics: influence on renal function.

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Reversible inhibition of mitochondrial complex IV activity in PBMC following acute smoking

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Oxygen radical-dependent epoxidation of (7S,8S)-dihydroxy-7,8-dihydrobenzo[a]pyrene in mouse skin in vivo. Stimulation by phorbol esters and inhibition by antiinflammatory steroids.

1992 • 49 citations

Biochemical Evidence of Atherosclerosis Progression Mediated by Increased Oxidative Stress in Apolipoprotein E–Deficient Spontaneously Hyperlipidemic Mice Exposed to Chronic Cigarette Smoke

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Short-Term Systemic Effects of Nose-Only Cigarette Smoke Exposure in Mice: Role of Oxidative Stress

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Alterations in Glutathione Redox Metabolism, Oxidative Stress, and Mitochondrial Function in the Left Ventricle of Elderly Zucker Diabetic Fatty Rat Heart

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Contribution of Myeloperoxidase to Smoking-dependent Vascular Inflammation

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Plasma copper and lipid peroxidation in cigarette smokers

1995 • 47 citations

Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine

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Effect of cigarette smoke on CYP1A1, CYP1A2 and CYP2B1/2 of nasal mucosae in F344 rats

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Formation of 8-methylguanine as a result of DNA alkylation by methyl radicals generated during horseradish peroxidase-catalyzed oxidation of methylhydrazine.

1990 • 46 citations

Smoking and Cardiovascular Disease

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Dietary supplementation with antioxidants. Is there a case for exceeding the recommended dietary allowance?

1987 • 44 citations

Chicken liver ribosomes: Characterization of cross-reaction and inhibition of some functions by antibodies prepared against Escherichia coli ribosomal proteins L7 and L12

1976 • 42 citations

The inhibitory effect of extracts of cigarette tar on electron transport of mitochondria and submitochondrial particles

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Mechanisms of cigarette smoke toxicity: the inactivation of human α-1-proteinase inhibitor by nitric oxide/isoprene mixtures in air

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Smoking as a modifier of the systolic blood pressure-induced risk of cardiovascular events and mortality: a population-based prospective study of middle-aged men

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Reduction in oral mucosa micronuclei frequency following alpha-tocopherol treatment of oral leukoplakia.

1994 • 40 citations

Biochemical and morphological effects of cigarette smoke condensate and its fractions on normal human bronchial epithelial cells in vitro.

1987 • 40 citations

Oxidative damage and antioxidant status in the lungs and bronchoalveolar lavage fluid of rats exposed chronically to cigarette smoke.

1995 • 40 citations

Constitutive and Inducible Cytochromes P450 in Rat Lung Mitochondria: Xenobiotic Induction, Relative Abundance, and Catalytic Properties

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Superoxide organic chemistry within the liposomal bilayer, part II: a correlation between location and chemistry

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Effect of cigarette smoke inhalation on antioxidant enzymes and lipid peroxidation in the rat

1988 • 38 citations

Peroxyl radical- and cytochrome P-450-dependent metabolic activation of (+)-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene in mouse skin in vitro and in vivo.

1989 • 38 citations

Cardiovascular responses to cigarette smoke exposure in restrained conscious rats.

1995 • 37 citations

Synthesis and structure determination of the adducts formed by electrochemical oxidation of the potent carcinogen dibenzo[a,l]pyrene in the presence of nucleosides

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Evaluation of the pulmonary effects of short-term nose-only cigarette smoke exposure in mice

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Formation of cigarette smoke-induced DNA adducts in the rat lung and nasal mucosa.

1989 • 35 citations

Damage to human .alpha.-1-proteinase inhibitor by aqueous cigarette tar extracts and the formation of methionine sulfoxide

1992 • 35 citations

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Formation of ribonucleotides in DNA modified by oxidative damage in vitro and in vivo. Characterization by 32P-postlabeling

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Improved electrophoretic and immunochemical techniques for the identification and characterization of mutant proteins, applied to ribosomal protein S8 in Escherichia coli mutants

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Cardiovascular Remodeling Induced by Passive Smoking

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DNA damage induced by cigarette smoke condensate in vitro as assayed by 32P-postlabeling. Comparison with cigarette smoke-associated DNA adduct profiles in vivo

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Cigarette smoke causes rapid lipid peroxidation of rat tracheal epithelium.

1993 • 30 citations

High-performance liquid chromatography with electrochemical detection for determination of the major malondialdehyde-guanine adduct

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Inhaled cigarette smoke induces the formation of DNA adducts in lungs of rats

1989 • 30 citations

Measurement of oxidative stress status in humans.

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Quantitative measurements of NO reaction kinetics with a Clark-type electrode

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Increased vascular contractility in isolated vessels from cigarette smoking rats is mediated by basal endothelin release

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Protective antioxidant mechanisms in rat and guinea pig tissues challenged by acute exposure to cigarette smoke

1992 • 29 citations

Smoking accelerates the progression of hypertension-induced myocardial hypertrophy to heart failure in spontaneously hypertensive rats☆

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Aqueous cigarette tar extracts damage human alpha-1-proteinase inhibitor

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Metabolism of 4‐hydroxynonenal by the rat heptoma cell line MH₁C₁

1988 • 26 citations

Left ventricular growth response to exercise and cigarette smoking: data from LARGE Heart

2006 • 26 citations

Phosphorus-32-postlabeling analysis of benzo[a]pyrene-DNA adducts formed in vitro and in vivo

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Cigarette Smoke Exposure Promotes Arterial Thrombosis and Vessel Remodeling after Vascular Injury in Apolipoprotein E-Deficient Mice

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Reductive alkylation of ribosomes as a probe to the topography of ribosomal proteins

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The effect of mainstream and sidestream cigarette smoke exposure on oxygen defense mechanisms of guinea pig erythrocytes

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Electrophysiological effects of O₂⁻· on the plasma membrane in vascular endothelial cells

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Adducts of 6-methylbenzo[a]pyrene and 6-fluorobenzo[a]pyrene formed by electrochemical oxidation in the presence of deoxyribonucleosides

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Cigarette exposure induces changes in maternal vascular function in a pregnant mouse model

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Potential Inhibitors of Tobacco Carcinogenesisa

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Antibodies to Ribosomes in Chronic Active Hepatitis

1979 • 11 citations

Combined exposure to cigarette smoke and hypercholesterolemia decreases vasorelaxation of the aorta

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Phosphorus-32-postlabeling analysis of the DNA adducts of 6-fluorobenzo[a]pyrene and 6-methylbenzo[a]pyrene formed in vitro

1993 • 9 citations

Modulation of xenobiotic metabolism and oxidative stress in chronic streptozotocin-induced diabetic rats fed with Momordica charantia fruit extract

2000 • 9 citations

Application of carbon fiber composite minielectrodes for measurement of kinetic constants of nitric oxide decay in solution

2010 • 8 citations