Metabolism of 4‐hydroxynonenal by the rat heptoma cell line MH₁C₁

Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

1980 • 1,094 citations

Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes

1982 • 614 citations

4‐Hydroxyalk‐2‐enals are substrates for glutathione transferase

1985 • 422 citations

Aldehydes in biological systems

1977 • 259 citations

Metabolism of the lipid peroxidation product 4-hydroxynonenal by isolated hepatocytes and by liver cytosolic fractions

1985 • 235 citations

Analysis of biological thiols: Quantitative determination of thiols at the picomole level based upon derivatization with monobromobimanes and separation by cation-exchange chromatography

1981 • 198 citations

Role of cardiac glutathione transferase and of the glutathione S-conjugate export system in biotransformation of 4-hydroxynonenal in the heart.

1986 • 187 citations

Studies on the mechanism of formation of 4-hydroxynonenal during microsomal lipid peroxidation

1986 • 173 citations

Rat glutathione transferase 8‐8, an enzyme efficiently detoxifying 4‐hydroxyalk‐2‐enals

1986 • 155 citations

ESTABLISHMENT OF A CLONAL STRAIN OF HEPATOMA CELLS WHICH SECRETE ALBUMIN

1969 • 137 citations

Biochemical Basis of Chemical Carcinogenesis

1985 • 132 citations

Quantitative determination of the lipid peroxidation product 4-hydroxynonenal by high-performance liquid chromatography

1985 • 123 citations

Cytotoxicity, thiol depletion and inhibition of O⁶-methylguanine-DNA methyltransferase by various aldehydes in cultured human bronchial fibroblasts

1985 • 122 citations

Growth-related lipid peroxidation in tumour microsomal membranes and mitochondria

1979 • 102 citations

Trans -4-Hydroxy-2-Hexenal: a Reactive Metabolite from the Macrocyclic Pyrrolizidine Alkaloid Senecionine

1985 • 85 citations

Expression of cytochromes P-450 in rat hepatoma cells. Analysis by monoclonal antibodies specific for cytochromes P-450 from rat liver induced by 3-methylcholanthrene or phenobarbital

1984 • 69 citations

Lipid peroxidation in hepatomas of different degrees of deviation

1983 • 40 citations

Further Experiments on Lipid Peroxidation in Transplanted and Experimental Hepatomas

1984 • 27 citations

Metabolism of the pyrrolizidine alkaloid metabolite trans-4-hydroxy-2-hexenal by mouse liver aldehyde dehydrogenases

1986 • 26 citations

NADPH-Dependent Lipid Peroxidation in Mitochondria from Livers of Young and Old Rats and from Rat Hepatoma D30

1977 • 25 citations

Hydroxylation and sulfation of bile acids in rat hepatoma cultures under the influence of a glucocorticoid

1979 • 23 citations

Induction of cytochrome P‐450 isozymes in rat hepatoma‐derived cell cultures

1984 • 19 citations

Induction of cytochrome(s) P₄₅₀‐dependent drug metabolism in cultured MH₁C₁ hepatoma cells

1984 • 12 citations