The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin

2016 • 7,054 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

The scanning model for translation: an update.

1989 • 3,525 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc

1991 • 1,650 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

Helix stabilization by Glu-...Lys+ salt bridges in short peptides of de novo design.

1987 • 930 citations

[12] Unidirectional digestion with exonuclease III in DNA sequence analysis

1987 • 898 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

RNA recognition: towards identifying determinants of specificity

1991 • 739 citations

RNA-binding proteins as developmental regulators.

1989 • 679 citations

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

1989 • 601 citations

Recognition of cap structure in splicing in vitro of mRNA precursors

1984 • 575 citations

How proteins enter the nucleus

1991 • 555 citations

THE FAMILY OF COLLAGEN GENES

1990 • 511 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

Poly(A) signals

1991 • 438 citations

α-Thalassaemia caused by a polyadenylation signal mutation

1983 • 407 citations

Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box

1989 • 303 citations

A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs.

1990 • 243 citations

Characterization of a Dimerization Motif in AP-2 and Its Function in Heterologous DNA-Binding Proteins

1991 • 234 citations

Four factors are required for 3'-end cleavage of pre-mRNAs.

1989 • 217 citations

Polyadenylation of mRNA precursors

1988 • 210 citations

3′ cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP

1988 • 205 citations

Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation

1988 • 195 citations

An ordered pathway of assembly of components required for polyadenylation site recognition and processing.

1989 • 194 citations

A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif

1988 • 187 citations

Poly(A) site efficiency reflects the stability of complex formation involving the downstream element.

1991 • 140 citations

Bioassay for trans-activation using purified human immunodeficiency virus tat-encoded protein: trans-activation requires mRNA synthesis.

1989 • 132 citations

Two proteins crosslinked to RNA containing the adenovirus L3 poly(A) site require the AAUAAA sequence for binding.

1988 • 111 citations

Molecular analyses of two poly(A) site-processing factors that determine the recognition and efficiency of cleavage of the pre-mRNA.

1991 • 111 citations

Analysis of RNA cleavage at the adenovirus-2 L3 polyadenylation site.

1986 • 94 citations

A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates.

1990 • 87 citations

A beginning to the biochemistry of polyadenylation

1988 • 84 citations

Stabilization of the long central helix of troponin C by intrahelical salt bridges between charged amino acid side chains.

1985 • 80 citations

Multiple forms of poly(A) polymerases purified from HeLa cells function in specific mRNA 3'-end formation.

1989 • 65 citations

Products of in vitro cleavage and polyadenylation of simian virus 40 late pre-mRNAs.

1987 • 64 citations

RNA synthesis in isolated nuclei

1982 • 59 citations

Molecular Analyses of Two Poly(A) Site-Processing Factors That Determine the Recognition and Efficiency of Cleavage of the Pre-mRNA

1991 • 48 citations

The enzyme that adds poly(A) to mRNAs is a classical poly(A) polymerase.

1990 • 42 citations

A Multicomponent Complex Is Required for the AAUAAA-Dependent Cross-Linking of a 64-Kilodalton Protein to Polyadenylation Substrates

1990 • 39 citations

Role of poly(A) polymerase in the cleavage and polyadenylation of mRNA precursor.

1989 • 36 citations

Products of In Vitro Cleavage and Polyadenylation of Simian Virus 40 Late Pre-mRNAs

1987 • 35 citations

[60] Hybrid selection of mRNA and hybrid arrest of translation

1987 • 28 citations

Multiple Forms of Poly(A) Polymerases Purified from HeLa Cells Function in Specific mRNA 3′-End Formation

1989 • 17 citations

Role of Poly(A) Polymerase in the Cleavage and Polyadenylation of mRNA Precursor

1989 • 15 citations